Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 46 time(s) and present in 45 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
USAUSA Hawaii Okinawa0.1300106See
VENVenezuela Perja Mountain Bari0.114055See
ZAFSouth Africa Caucasians0.0870102See
MEXMexico Hidalgo Mezquital Valley/ Otomi15.30.076472See
RUSRussian Federation Vologda Region13.40.0714119See
ENGEngland Blood Donors of Mixed Ethnicity13.50.0684519See
GEOGeorgia Tibilisi0.0600109See
USAUSA San Francisco Caucasian0.0600220See
POLPoland BMR10.50.053523595See
CHNChina Zhejiang Han0.04501734See
BGRBulgaria Romani0.045013See
CHNChina South Han0.0440284See
BRABrazil Barra Mansa Rio State Black0.041173See
CHNChina Jingpo Minority7.80.0390105See
CRICosta Rica Central Valley Mestizo (G)7.80.0390221See
CRICosta Rica Amerindians (G)7.40.0370125See
USAUSA Mexican American Mestizo0.0350553See
ESPSpain, Canary Islands, Gran canaria island6.50.0326215See
BRABrazil Rio de Janeiro Caucasian0.0326521See
CRICosta Rica Guanacaste Mestizo (G)6.40.0320110See
SGPSingapore Javaneses0.031051See
BRABrazil Barra Mansa Rio State Caucasian0.0309405See
ZAFSouth African Mixed ancestry6.00.030050See
BRABrazil Rio de Janeiro Black0.029968See
SGPSingapore Chinese Han0.029094See
HKGHong Kong Chinese HKBMDR HLA 11 loci4.70.02425266See
NICNicaragua Mestizo (G)4.60.0230155See
RUSRussia Belgorod region4.60.0229153See
BRABrazil Mixed0.0220108See
BRABrazil Rio de Janeiro Parda0.0176170See
SGPSingapore Riau Malay0.0150132See
RUSRussia Nizhny Novgorod, Russians2.60.01291510See
GRCGreece Athens2.40.01221888See
USAUSA New Mexico Canoncito Navajo0.012042See
USAUSA Arizona Pima0.0110100See
ZAFSouth African Black2.10.0106142See
SGPSingapore Thai0.0100100See
VNMVietnam Kinh2.00.0099101See
INDIndia Andhra Pradesh Telugu Speaking1.60.0081186See
INDIndia New Delhi0.008071See
RUSRussia Bashkortostan, Tatars1.00.0052192See
CRICosta Rica African -Caribbean (G)1.00.0050102See
SAUSaudi Arabia pop 6 (G)0.003828927See
USAUSA Arizona Gila River Pima0.00203000See
MARMorocco Settat Chaouya0.00.000098See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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