Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 30 time(s) and present in 30 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia Karnataka Kannada Speaking17.20.0890174See
GRCGreece Athens13.80.06891888See
INDIndia Andhra Pradesh Telugu Speaking11.80.0645186See
ZAFSouth African Indian population10.00.050050See
INDIndia Kerala Malayalam speaking8.40.0440356See
RUSRussia Belgorod region7.20.0359153See
POLPoland BMR6.40.032323595See
BRABrazil Barra Mansa Rio State Caucasian0.0321405See
ZAFSouth African Mixed ancestry6.00.030050See
RUSRussia Bashkortostan, Tatars5.20.0260192See
RUSRussian Federation Vologda Region5.00.0252119See
BRABrazil Rio de Janeiro Black0.022468See
RUSRussia Nizhny Novgorod, Russians4.20.02221510See
SAUSaudi Arabia pop 6 (G)0.021228927See
LBYLibya Cyrenaica0.0210118See
CRICosta Rica Central Valley Mestizo (G)3.60.0180221See
BRABrazil Rio de Janeiro Caucasian0.0173521See
RUSRussia Bashkortostan, Bashkirs3.30.0167120See
SAUSaudi Arabia pop 52.50.0158158See
BRABrazil Barra Mansa Rio State Black0.013773See
NICNicaragua Mestizo (G)2.60.0130155See
BRABrazil Rio de Janeiro Parda0.0118170See
HKGHong Kong Chinese HKBMDR HLA 11 loci1.90.00945266See
ESPSpain, Canary Islands, Gran canaria island1.40.0093215See
USAUSA San Francisco Caucasian0.0090220See
CRICosta Rica Guanacaste Mestizo (G)1.00.0050110See
VNMVietnam Kinh1.00.0050101See
ENGEngland Blood Donors of Mixed Ethnicity1.00.0048519See
CHNChina Zhejiang Han0.00401734See
USAUSA Arizona Gila River Pima0.00033000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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