Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 50 time(s) and present in 48 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia Andhra Pradesh Golla0.0870111See
ZAFSouth African Indian population16.00.080050See
INDIndia Andhra Pradesh Telugu Speaking8.60.0430186See
INDIndia Kerala Malayalam speaking7.30.0380356See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
CRICosta Rica Central Valley Mestizo (G)5.40.0270221See
RUSRussia Bashkortostan, Tatars4.70.0234192See
ENGEngland Blood Donors of Mixed Ethnicity4.10.0212519See
CANCanada Chipewyan NA-DHS_2 (G)4.00.020025See
ZAFSouth Africa Natal Tamil0.020051See
SGPSingapore Javaneses0.020051See
ENGEngland North West3.70.0180298See
RUSRussia Bashkortostan, Bashkirs3.30.0167120See
ESPSpain, Canary Islands, Gran canaria island3.30.0163215See
USAUSA Italy Ancestry0.0160273See
GRCGreece Athens2.90.01431888See
RUSRussia Nizhny Novgorod, Russians2.30.01131510See
POLPoland BMR2.20.011223595See
SAUSaudi Arabia pop 6 (G)0.011128927See
USAUSA San Francisco Caucasian0.0110220See
INDIndia Karnataka Kannada Speaking2.30.0110174See
CRICosta Rica African -Caribbean (G)2.00.0100102See
CHNChina Jingpo Minority1.90.0100105See
ZAFSouth African Mixed ancestry2.00.010050See
RUSRussia Belgorod region2.00.0098153See
GEOGeorgia Tibilisi0.0090109See
BRABrazil Rio de Janeiro Parda0.0088170See
BRABrazil Barra Mansa Rio State Caucasian0.0086405See
BRABrazil Rio de Janeiro Caucasian0.0086521See
CHNChina Zhejiang Han0.00811734See
INDIndia New Delhi0.008071See
BRABrazil Rio de Janeiro Black0.007568See
BRABrazil Mixed0.0070108See
MEXMexico Hidalgo Mezquital Valley/ Otomi1.40.006972See
BRABrazil Barra Mansa Rio State Black0.006873See
SGPSingapore Chinese Han0.006094See
USAUSA Arizona Pima0.0060100See
USAUSA Spain Ancestry0.0050279See
CRICosta Rica Guanacaste Mestizo (G)1.00.0050110See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0050146See
VNMVietnam Kinh1.00.0050101See
HKGHong Kong Chinese HKBMDR HLA 11 loci1.00.00485266See
RUSRussian Federation Vologda Region0.80.0042119See
CRICosta Rica Amerindians (G)0.80.0040125See
USAUSA Mexican American Mestizo0.0040553See
NICNicaragua Mestizo (G)0.60.0030155See
IDNIndonesia Sundanese and Javanese0.0030201See
USAUSA Arizona Gila River Pima0.00033000See
IDNIndonesia Java pop 20.000036See
MARMorocco Settat Chaouya0.00.000098See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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