Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 140 time(s) and present in 105 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
USAUSA NMDP Filipino0.127250614See
TWNTaiwan Tao20.00.110050See
CHNChina Guangxi Region Maonan0.0830108See
MYSMalaysia Kedah Baling Kensiu0.080025See
CHNChina Sichuan HIV negative0.074034See
CHNChina South Han0.0710284See
SGPSingapore Javaneses0.071051See
CHNChina Canton Han0.0700264See
USAUSA Asian0.0660358See
SGPSingapore Chinese Han0.064094See
TWNTaiwan Minnan pop 112.70.0640102See
PHLPhilippines Ivatan12.00.060050See
CHNChina Guangzhou0.0600102See
USAUSA NMDP Vietnamese0.058443540See
VNMVietnam Hanoi Kinh pop 20.0560170See
CHNChina Southwest Dai0.0560124See
HKGHong Kong Chinese10.00.0540569See
IDNIndonesia Java Western10.60.0540236See
MYSMalaysia Champa10.30.052029See
MYSMalaysia Peninsular Chinese9.80.0516194See
HKGHong Kong Chinese BMDR0.04947595See
HKGHong Kong Chinese cord blood registry0.04903892See
TWNTaiwan Tzu Chi Morrow Donor Registry0.047246682See
SGPSingapore Chinese9.40.0470149See
SGPSingapore Riau Malay0.0450132See
TWNTaiwan Tzu Chi Cord Blood Bank0.0440710See
CHNChina Guangzhou Han0.0430106See
MYSMalaysia Jelebu Temuan0.042025See
SGPSingapore SGVP Malay MAS0.042089See
INDIndia Northeast UCBB8.10.0405296See
INDIndia West Bhil0.040050See
USAUSA NMDP Chinese0.040099672See
TWNTaiwan pop 20.0380364See
SGPSingapore SGVP Chinese CHS0.038096See
MYSMalaysia Peninsular Malay7.40.0379951See
MYSMalaysia Mandailing7.40.037027See
USAUSA Asian pop 20.03651772See
TWNTaiwan Hakka7.30.036055See
MYSMalaysia Kelantan7.10.036028See
SGPSingapore Thai0.0350100See
TWNTaiwan Han Chinese0.0330504See
CHNChina Marrow Donor Registry0.0320600See
CHNChina Yunnan Bulang0.0300116See
TWNTaiwan Siraya5.90.029051See
DEUGermany DKMS - China minority0.02691282See
TWNTaiwan pop 30.0260212See
CHNChina Yunnan Province Han0.0250101See
MYSMalaysia Kedah Kensiu4.80.024021See
CHNChina Hubei Han4.30.02173732See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0215233See
CHNChina Jiangsu Han0.02103238See
MYSMalaysia Perak Grik Jehai0.020025See
MYSMalaysia Patani4.00.020025See
CHNChina Jiangsu Province Han0.0192334See
CHNChina Beijing Shijiazhuang Tianjian Han0.0190618See
SGPSingapore SGVP. Indian INS0.019086See
TWNTaiwan Pazeh3.60.018055See
USAUSA NMDP Hawaiian or other Pacific Islander0.017411499See
INDIndia East UCBB3.30.01622403See
USAUSA NMDP Southeast Asian0.015127978See
USAUSA San Diego2.60.0130496See
INDIndia Mumbai Maratha0.012091See
KORSouth Korea pop 30.0110485See
TWNTaiwan Saisiat2.00.010051See
TWNTaiwan Puyuma2.00.010050See
USAUSA NMDP Korean0.009677584See
MYSMalaysia Peninsular Indian1.80.0092271See
KORSouth Korea pop 100.00804128See
CHNChina Beijing0.008067See
INDIndia West UCBB1.60.00795829See
INDIndia Tamil Nadu0.00772492See
INDIndia Central UCBB1.50.00734204See
INDIndia South UCBB1.50.007311446See
BRABrazil Mixed0.0070108See
CHNChina Yunnan Hani0.0070150See
USAUSA NMDP South Asian Indian0.0069185391See
LKASri Lanka Colombo1.10.0060714See
INDIndia North UCBB0.90.00435849See
JPNJapan pop 50.0040117See
USAUSA NMDP Japanese0.003324582See
JPNJapan pop 160.002818604See
USAUSA Caucasian pop 20.0020265See
JPNJapan pop 30.00201018See
MKDMacedonia pop 40.0020216See
NLDNetherlands Leiden0.00101305See
JPNJapan Central0.0010371See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA NMDP Caribean Indian0.001014339See
USAUSA NMDP Caribean Black0.000633328See
DEUGermany DKMS - Portugal minority0.00041176See
USAUSA NMDP Mexican or Chicano0.0003261235See
USAUSA NMDP North American Amerindian0.000335791See
USAUSA NMDP Hispanic South or Central American0.0002146714See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000270890See
DEUGermany DKMS - Turkey minority0.00024856See
USAUSA NMDP African0.000128557See
DEUGermany pop 80.000139689See
CZECzech Republic NMDR0.00015099See
USAUSA NMDP Caribean Hispanic0.0001115374See
USAUSA NMDP African American pop 20.0001416581See
DEUGermany DKMS - German donors0.00013456066See
USAUSA NMDP European Caucasian0.00001242890See
ISRIsrael USSR Jews0.000045681See
ISRIsrael YemenJews0.000015542See
ITAItaly North pop 30.00.000097See
ITAItaly pop 50.0000975See
INDIndia Khandesh Region Pawra0.000050See
NIRIreland Northern0.00.00001000See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
DEUGermany pop 60.00018862See
INDIndia West Coast Parsi0.000050See
CHNChina North Han0.0000105See
AUSAustralia Yuendumu Aborigine0.0000191See
AUSAustralia New South Wales Caucasian0.0000134See
BRABrazil Belo Horizonte Caucasian0.00.000095See
USAUSA African American pop 80.0000605See
USAUSA African American pop 40.00002411See
USAUSA Hispanic pop 20.00001999See
USAUSA North American Native0.0000187See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA European American pop 20.00001245See
USAUSA African American0.0000252See
USAUSA Hispanic0.0000234See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
POLPoland DKMS0.000020653See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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