Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 23 time(s) and present in 22 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CRICosta Rica Amerindians (G)57.80.3580125See
USAUSA Spain Ancestry0.1080279See
NICNicaragua Mestizo (G)20.80.1070155See
CRICosta Rica Central Valley Mestizo (G)16.30.0930221See
MEXMexico Hidalgo Mezquital Valley/ Otomi15.30.083372See
USAUSA Arizona Gila River Pima0.07643000See
CRICosta Rica Guanacaste Mestizo (G)13.60.0680110See
USAUSA Mexican American Mestizo0.0670553See
CHNChina Tibet Region Tibetan0.0570158See
CHNChina Yunnan Province Lisu0.0360111See
ESPSpain, Canary Islands, Gran canaria island3.70.0209215See
ZAFSouth African Mixed ancestry4.00.020050See
USAUSA Eastern European0.0200558See
POLPoland BMR3.50.017723595See
ENGEngland Blood Donors of Mixed Ethnicity2.70.0135519See
USAUSA San Francisco Caucasian0.0090220See
USAUSA Italy Ancestry0.0070273See
INDIndia Kerala Malayalam speaking1.40.0070356See
SAUSaudi Arabia pop 51.30.0063158See
USAUSA African American pop 30.0050564See
IDNIndonesia Sundanese and Javanese0.0030201See
INDIndia Andhra Pradesh Telugu Speaking0.50.0027186See
IDNIndonesia Java pop 20.000036See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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