Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 30 time(s) and present in 30 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ENGEngland Blood Donors of Mixed Ethnicity21.40.1098519See
USAUSA San Francisco Caucasian0.0690220See
RUSRussia Belgorod region11.80.0621153See
BRABrazil Rio de Janeiro Black0.059768See
ZAFSouth Africa Caucasians0.0560102See
CRICosta Rica Central Valley Mestizo (G)10.80.0540221See
BRABrazil Rio de Janeiro Caucasian0.0537521See
ESPSpain, Canary Islands, Gran canaria island10.70.0535215See
POLPoland BMR9.20.046623595See
BRABrazil Barra Mansa Rio State Caucasian0.0407405See
BRABrazil Rio de Janeiro Parda0.0324170See
CRICosta Rica Guanacaste Mestizo (G)6.40.0320110See
GRCGreece Athens6.40.03181888See
RUSRussian Federation Vologda Region5.90.0294119See
NICNicaragua Mestizo (G)5.20.0260155See
MEXMexico Hidalgo Mezquital Valley/ Otomi4.20.020872See
RUSRussia Bashkortostan, Bashkirs3.30.0167120See
SAUSaudi Arabia pop 6 (G)0.011328927See
ZAFSouth African Indian population2.00.010050See
CRICosta Rica African -Caribbean (G)2.00.0100102See
CRICosta Rica Amerindians (G)1.60.0080125See
BRABrazil Barra Mansa Rio State Black0.006873See
INDIndia Kerala Malayalam speaking1.10.0060356See
INDIndia Andhra Pradesh Telugu Speaking1.10.0054186See
RUSRussia Bashkortostan, Tatars1.00.0052192See
CHNChina Zhejiang Han0.00371734See
ZAFSouth African Black0.70.0035142See
INDIndia Karnataka Kannada Speaking0.60.0030174See
RUSRussia Nizhny Novgorod, Russians0.50.00271510See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.30.00155266See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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