Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 160 time(s) and present in 107 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
IRNIran Yazd0.017956See
CHESwitzerland Aargau-Solothurn0.01211838See
GRCGreece pop 60.0118242See
DEUGermany DKMS - Romania minority0.01141234See
ZMBZambia Lusaka0.011044See
ZAFSouth Africa Caucasians0.0100102See
AREUnited Arab Emirates Abu Dhabi0.009652See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0090146See
PRTAzores Central Islands0.009059See
POLPoland DKMS0.008520653See
DEUGermany DKMS - Croatia minority0.00832057See
HRVCroatia pop 40.00814000See
CPVCape Verde Southeastern Islands0.008062See
DEUGermany DKMS - Greece minority0.00771894See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00731028See
BRABrazil Mixed0.0070108See
DEUGermany DKMS - Netherlands minority0.00691374See
CZECzech Republic NMDR0.00665099See
DEUGermany DKMS - Italy minority0.00651159See
DEUGermany pop 80.006239689See
GRCGreece pop 81.20.006083See
ITAItaly pop 50.0060975See
USAUSA Eastern European0.0060558See
DEUGermany DKMS - Austria minority0.00591698See
DEUGermany DKMS - Turkey minority0.00554856See
DEUGermany DKMS - Spain minority0.00541107See
DEUGermany DKMS - France minority0.00531406See
CHESwitzerland Bern0.00523545See
BRABrazil Belo Horizonte Caucasian1.10.005095See
CZECzech Republic0.0050106See
GEOGeorgia Tibilisi0.0050109See
SRBSerbia pop 21.00.0050102See
DEUGermany DKMS - German donors0.00503456066See
CHESwitzerland St Gallen0.00492113See
CHESwitzerland Geneva pop 20.00471267See
DEUGermany pop 60.00478862See
RUSRussia Karelia0.00421075See
USAUSA NMDP Middle Eastern or North Coast of Africa0.004170890See
NLDNetherlands Leiden0.00401305See
AUSAustralia New South Wales Caucasian0.0040134See
FRAFrance Southeast0.80.0040130See
USAUSA Philadelphia Caucasian0.70.0040141See
CHESwitzerland Basel0.00381888See
ISRIsrael Ashkenazi Jews pop 30.00364625See
CHESwitzerland Zurich0.00344875See
DEUGermany DKMS - Portugal minority0.00341176See
ISRIsrael Tunisia Jews0.00339070See
DEUGermany DKMS - United Kingdom minority0.00341043See
ISRIsrael Libya Jews0.00323739See
NICNicaragua Managua0.60.0030339See
USAUSA San Diego0.60.0030496See
USAUSA North American Native0.0030187See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.60.00294335See
USAUSA NMDP European Caucasian0.00291242890See
ISRIsrael Iraq Jews0.002513270See
ISRIsrael USSR Jews0.002545681See
ISRIsrael Morocco Jews0.002336718See
ENGEngland North West0.30.0020298See
CHESwitzerland Sion0.0020832See
USAUSA Hispanic0.0020234See
USAUSA Spain Ancestry0.0020279See
USAUSA Italy Ancestry0.0020273See
USAUSA Caucasian pop 40.00191070See
ISRIsrael Poland Jews0.001813871See
CHESwitzerland Luzern0.00171553See
USAUSA Hispanic pop 20.00181999See
USAUSA NMDP North American Amerindian0.001435791See
ISRIsrael Argentina Jews0.00144307See
COLColombia Bogotá Cord Blood0.30.00141463See
USAUSA NMDP Hispanic South or Central American0.0013146714See
USAUSA NMDP Mexican or Chicano0.0011261235See
ISRIsrael Kavkazi Jews0.00112840See
USAUSA NMDP American Indian South or Central America0.00105926See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA NMDP Caribean Indian0.001014339See
USAUSA Mexican American Mestizo0.0010553See
USAUSA African American pop 30.0010564See
NIRIreland Northern0.10.00101000See
USAUSA European American pop 20.00101245See
ISRIsrael YemenJews0.001015542See
ISRIsrael USA Jews0.00106058See
ISRIsrael Druze0.00095914See
USAUSA NMDP Caribean Hispanic0.0008115374See
ISRIsrael Arab pop 20.000612301See
USAUSA African American pop 40.00042411See
SAUSaudi Arabia pop 6 (G)0.000328927See
ISRIsrael Georgia Jews0.00034471See
USAUSA NMDP Caribean Black0.000333328See
DEUGermany DKMS - China minority0.00041282See
USAUSA NMDP African American pop 20.0003416581See
USAUSA NMDP Hawaiian or other Pacific Islander0.000311499See
USAUSA NMDP African0.000228557See
INDIndia West UCBB0.00.00025829See
USAUSA NMDP Southeast Asian0.000127978See
USAUSA NMDP Filipino0.000150614See
ISRIsrael Iran Jews0.00018153See
ISRIsrael Bukhara Jews0.00012317See
USAUSA NMDP Japanese0.000124582See
ISRIsrael Ethiopia Jews0.00015928See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Korean0.000077584See
USAUSA NMDP Vietnamese0.000043540See
SGPSingapore Chinese0.00.0000149See
PHLPhilippines Ivatan0.00.000050See
PRTAzores Oriental Islands0.000043See
USAUSA African American pop 80.0000605See
USAUSA Asian pop 20.00001772See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
MLIMali Bandiagara0.0000138See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
UGAUganda Kampala0.0000161See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
GNBGuinea Bissau0.000065See
HKGHong Kong Chinese0.00.0000569See
CPVCape Verde Northwestern Islands0.000062See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
AUSAustralia Yuendumu Aborigine0.0000191See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA Asian0.0000358See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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