Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 153 time(s) and present in 99 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
GEOGeorgia Tibilisi0.0230109See
INDIndia New Delhi0.023071See
SGPSingapore Chinese Han0.023094See
SENSenegal Niokholo Mandenka0.0160165See
CHESwitzerland Sion0.0145832See
MEXMexico Mestizo2.40.012041See
SGPSingapore SGVP Chinese CHS0.011096See
INDIndia West Coast Parsi0.010050See
IRNIran Saqqez-Baneh Kurds0.008360See
IRNIran Kurd pop 20.008060See
SGPSingapore SGVP Malay MAS0.006089See
IRNIran Tabriz Azeris0.005297See
INDIndia Andhra Pradesh Golla0.0050111See
ISRIsrael Arab Druze0.0050101See
CHNChina North Han0.0050105See
ARMArmenia combined Regions0.0050100See
CHLChile Santiago Mixed1.00.005070See
TWNTaiwan Minnan pop 11.00.0050102See
DEUGermany DKMS - Turkey minority0.00454856See
DEUGermany DKMS - Greece minority0.00401894See
CHESwitzerland Lausanne0.0033993See
CHESwitzerland Basel0.00311888See
SGPSingapore Chinese0.70.0030149See
INDIndia North UCBB0.60.00285849See
TWNTaiwan Tzu Chi Morrow Donor Registry0.002646682See
ISRIsrael Morocco Jews0.002636718See
INDIndia Tamil Nadu0.00252492See
GRCGreece pop 60.0024242See
CHESwitzerland Zurich0.00214875See
DEUGermany DKMS - Italy minority0.00221159See
SAUSaudi Arabia Guraiat and Hail0.50.0020213See
TWNTaiwan Tzu Chi Cord Blood Bank0.0020710See
INDIndia East UCBB0.40.00192403See
USAUSA NMDP Middle Eastern or North Coast of Africa0.001770890See
INDIndia Northeast UCBB0.30.0017296See
ISRIsrael Druze0.00165914See
INDIndia Central UCBB0.30.00164204See
ISRIsrael Arab pop 20.001512301See
USAUSA NMDP South Asian Indian0.0014185391See
USAUSA NMDP Southeast Asian0.001427978See
DEUGermany DKMS - Spain minority0.00141107See
DEUGermany DKMS - Romania minority0.00131234See
DEUGermany DKMS - France minority0.00111406See
DEUGermany DKMS - Netherlands minority0.00111374See
DEUGermany pop 80.001039689See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
ITAItaly pop 50.0010975See
HKGHong Kong Chinese0.20.0010569See
USAUSA Hispanic pop 20.00101999See
TWNTaiwan pop 20.0010364See
AREUnited Arab Emirates Pop 10.0010570See
USAUSA African American pop 80.0010605See
TWNTaiwan Han Chinese0.0010504See
USAUSA NMDP American Indian South or Central America0.00105926See
USAUSA NMDP Alaska Native or Aleut0.00101376See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.20.00104335See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00101028See
DEUGermany pop 60.00098862See
ISRIsrael Georgia Jews0.00094471See
INDIndia West UCBB0.20.00095829See
USAUSA NMDP Hispanic South or Central American0.0009146714See
USAUSA Asian pop 20.00091772See
USAUSA NMDP Chinese0.000899672See
DEUGermany DKMS - German donors0.00073456066See
DEUGermany DKMS - Croatia minority0.00072057See
COLColombia Bogotá Cord Blood0.10.00071463See
USAUSA NMDP Mexican or Chicano0.0006261235See
DEUGermany DKMS - Austria minority0.00061698See
USAUSA NMDP Caribean Hispanic0.0005115374See
SAUSaudi Arabia pop 6 (G)0.000528927See
HKGHong Kong Chinese cord blood registry0.00053892See
HRVCroatia pop 40.00054000See
POLPoland DKMS0.000620653See
USAUSA NMDP European Caucasian0.00051242890See
HKGHong Kong Chinese BMDR0.00057595See
DEUGermany DKMS - United Kingdom minority0.00051043See
ISRIsrael Tunisia Jews0.00049070See
INDIndia South UCBB0.10.000411446See
DEUGermany DKMS - China minority0.00041282See
CHNChina Hubei Han0.10.00033732See
USAUSA NMDP North American Amerindian0.000335791See
USAUSA NMDP Filipino0.000250614See
CZECzech Republic NMDR0.00025099See
ISRIsrael Kavkazi Jews0.00022840See
ISRIsrael USSR Jews0.000245681See
ISRIsrael Iran Jews0.00018153See
USAUSA NMDP Japanese0.000124582See
ISRIsrael Argentina Jews0.00014307See
ISRIsrael Ashkenazi Jews pop 30.00014625See
ISRIsrael YemenJews0.000115542See
USAUSA NMDP Vietnamese0.000143540See
USAUSA NMDP Hawaiian or other Pacific Islander0.000111499See
ISRIsrael Ethiopia Jews0.00015928See
USAUSA NMDP Caribean Black0.000133328See
USAUSA NMDP African0.000128557See
USAUSA NMDP African American pop 20.0001416581See
ISRIsrael Poland Jews0.000013871See
USAUSA NMDP Korean0.000077584See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American pop 40.00002411See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA European American pop 20.00001245See
PHLPhilippines Ivatan0.00.000050See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
ZAFSouth Africa Natal Zulu0.00.0000100See
SGPSingapore SGVP. Indian INS0.000086See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
NIRIreland Northern0.00.00001000See
KORSouth Korea pop 30.0000485See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
NLDNetherlands Leiden0.00001305See
CHNChina Tibet Region Tibetan0.0000158See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CHNChina Inner Mongolia Region0.0000102See
CHNChina Qinghai Province Hui0.0000110See
BRABrazil Belo Horizonte Caucasian0.00.000095See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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