Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 30 time(s) and present in 30 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia Kerala Malayalam speaking9.60.0520356See
INDIndia Karnataka Kannada Speaking5.20.0260174See
ENGEngland Blood Donors of Mixed Ethnicity5.00.0250519See
BOLBolivia/Chile Aymara NA-DHS_13 (G)5.00.025020See
GRCGreece Athens4.90.02441888See
INDIndia Andhra Pradesh Telugu Speaking4.30.0242186See
BRABrazil Barra Mansa Rio State Black0.020573See
USAUSA Italy Ancestry0.0200273See
ZAFSouth African Indian population4.00.020050See
CRICosta Rica Guanacaste Mestizo (G)2.80.0140110See
BRABrazil Rio de Janeiro Caucasian0.0115521See
POLPoland BMR2.20.011323595See
RUSRussia Bashkortostan, Tatars2.10.0104192See
SAUSaudi Arabia pop 6 (G)0.009728927See
ESPSpain, Canary Islands, Gran canaria island1.90.0093215See
USAUSA San Francisco Caucasian0.0090220See
RUSRussia Nizhny Novgorod, Russians1.80.00891510See
BRABrazil Rio de Janeiro Parda0.0088170See
BRABrazil Barra Mansa Rio State Caucasian0.0086405See
CRICosta Rica Central Valley Mestizo (G)1.40.0070221See
NICNicaragua Mestizo (G)1.40.0070155See
USAUSA Mexican American Mestizo0.0070553See
RUSRussia Belgorod region1.30.0065153See
USAUSA African American pop 30.0060564See
USAUSA Spain Ancestry0.0050279See
CRICosta Rica Amerindians (G)0.80.0040125See
SAUSaudi Arabia pop 50.60.0032158See
CHNChina Zhejiang Han0.00061734See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.10.00055266See
USAUSA Arizona Gila River Pima0.00023000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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