Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 129 time(s) and present in 90 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael Ethiopia Jews0.06645928See
CRICosta Rica Cabecar NA-DHS_9 (G)5.30.026319See
ZMBZambia Lusaka0.023044See
SENSenegal Niokholo Mandenka0.0160165See
KENKenya, Nyanza Province, Luo tribe3.00.0150100See
USAUSA African American0.0140252See
GHAGhana Ga-Adangbe2.30.0115131See
MLIMali Bandiagara0.0110138See
USAUSA African American Bethesda2.10.0110187See
UGAUganda Kampala pop 20.0110175See
TZATanzania Maasai2.10.0105336See
ZAFSouth Africa Natal Zulu2.00.0100100See
CMRCameroon Bakola Pygmy2.00.010050See
ZAFSouth Africa Worcester2.00.0090159See
USAUSA African American pop 80.0090605See
SDNSudan Mixed1.00.0080200See
GNBGuinea Bissau0.008065See
ZWEZimbabwe Harare Shona0.0070230See
CHESwitzerland Graubunden0.0069759See
USAUSA NMDP African0.006128557See
KENKenya Luo0.0060265See
SRBSerbia pop 21.00.0050102See
BRABrazil Belo Horizonte Caucasian1.10.005095See
USAUSA NMDP Caribean Black0.004333328See
USAUSA African American pop 40.00422411See
USAUSA Spain Ancestry0.0040279See
KENKenya Nandi0.0040240See
USAUSA NMDP African American pop 20.0038416581See
SAUSaudi Arabia pop 6 (G)0.003128927See
USAUSA San Antonio Caucasian0.0030222See
MEXMexico Mexico City Tlalpan0.60.0030330See
ISRIsrael Arab pop 20.002412301See
USAUSA San Francisco Caucasian0.0020220See
USAUSA NMDP Caribean Indian0.002014339See
ISRIsrael YemenJews0.001515542See
CHESwitzerland Zurich0.00134875See
USAUSA NMDP Caribean Hispanic0.0012115374See
USAUSA African American pop 30.0010564See
NIRIreland Northern0.10.00101000See
DEUGermany DKMS - Croatia minority0.00102057See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
ITAItaly pop 50.0010975See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.20.00104335See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00101028See
DEUGermany DKMS - Spain minority0.00091107See
DEUGermany DKMS - United Kingdom minority0.00101043See
USAUSA Caucasian pop 40.00091070See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000870890See
DEUGermany DKMS - Portugal minority0.00091176See
DEUGermany DKMS - Romania minority0.00081234See
CHESwitzerland Bern0.00073545See
COLColombia Bogotá Cord Blood0.10.00071463See
USAUSA NMDP Hispanic South or Central American0.0007146714See
HRVCroatia pop 40.00064000See
ISRIsrael Kavkazi Jews0.00052840See
ISRIsrael Georgia Jews0.00044471See
USAUSA NMDP Mexican or Chicano0.0004261235See
DEUGermany DKMS - Italy minority0.00041159See
DEUGermany DKMS - France minority0.00041406See
DEUGermany DKMS - Netherlands minority0.00041374See
DEUGermany DKMS - Austria minority0.00031698See
DEUGermany pop 80.000339689See
USAUSA NMDP European Caucasian0.00031242890See
DEUGermany DKMS - German donors0.00023456066See
USAUSA NMDP Southeast Asian0.000227978See
USAUSA Hispanic pop 20.00031999See
DEUGermany DKMS - Greece minority0.00031894See
ISRIsrael Ashkenazi Jews pop 30.00024625See
USAUSA NMDP North American Amerindian0.000235791See
ISRIsrael USSR Jews0.000145681See
ISRIsrael Poland Jews0.000113871See
DEUGermany DKMS - Turkey minority0.00014856See
DEUGermany pop 60.00028862See
CZECzech Republic NMDR0.00015099See
ISRIsrael Libya Jews0.00013739See
KORSouth Korea pop 100.00014128See
ISRIsrael Morocco Jews0.000136718See
USAUSA NMDP Hawaiian or other Pacific Islander0.000111499See
ISRIsrael Argentina Jews0.00014307See
ISRIsrael Tunisia Jews0.00019070See
ISRIsrael Iraq Jews0.000013270See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Japanese0.000024582See
ISRIsrael Druze0.00005914See
ISRIsrael USA Jews0.00006058See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP Korean0.000077584See
USAUSA NMDP Filipino0.000050614See
USAUSA Caucasian pop 20.0000265See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
USAUSA European American pop 20.00001245See
UGAUganda Kampala0.0000161See
USAUSA Asian pop 20.00001772See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA Hispanic0.0000234See
USAUSA North American Native0.0000187See
USAUSA Asian0.0000358See
HKGHong Kong Chinese0.00.0000569See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
CPVCape Verde Northwestern Islands0.000062See
CPVCape Verde Southeastern Islands0.000062See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
KORSouth Korea pop 30.0000485See
CHESwitzerland Aargau-Solothurn0.00001838See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Caucasians0.0000102See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
NLDNetherlands Leiden0.00001305See
POLPoland DKMS0.000120653See
MEXMexico Mestizo0.00.000041See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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