Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 25 time(s) and present in 25 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
HKGHong Kong Chinese HKBMDR HLA 11 loci16.90.08815266See
VNMVietnam Kinh17.00.0842101See
ZAFSouth African Black12.70.0704142See
INDIndia Kerala Malayalam speaking10.40.0530356See
ZAFSouth African Indian population10.00.050050See
INDIndia Karnataka Kannada Speaking9.80.0490174See
INDIndia Andhra Pradesh Telugu Speaking8.60.0430186See
COLColombia Inga NA-DHS_11 (G)7.10.035716See
LBYLibya Cyrenaica0.0340118See
SAUSaudi Arabia pop 6 (G)0.033828927See
MEXMexico Zapotec NA-DHS_7 (G)5.90.029420See
SAUSaudi Arabia pop 55.10.0253158See
CHLChile Huilliche NA-DHS_14 (G)5.00.025020See
CRICosta Rica African -Caribbean (G)5.00.0250102See
CRICosta Rica Guanacaste Mestizo (G)4.60.0230110See
ZAFSouth African Mixed ancestry4.00.020050See
CHNChina Jingpo Minority2.90.0150105See
ESPSpain, Canary Islands, Gran canaria island2.80.0140215See
MEXMexico Hidalgo Mezquital Valley/ Otomi2.80.013972See
NICNicaragua Mestizo (G)2.60.0130155See
USAUSA San Francisco Caucasian0.0110220See
CRICosta Rica Central Valley Mestizo (G)1.80.0090221See
ENGEngland Blood Donors of Mixed Ethnicity1.70.0087519See
POLPoland BMR1.40.007023595See
USAUSA Arizona Gila River Pima0.00023000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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