Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 26 time(s) and present in 26 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Hidalgo Mezquital Valley/ Otomi38.90.256972See
CRICosta Rica African -Caribbean (G)43.10.2350102See
CRICosta Rica Guanacaste Mestizo (G)36.50.2050110See
CRICosta Rica Central Valley Mestizo (G)33.00.1740221See
NICNicaragua Mestizo (G)27.00.1610155See
ESPSpain, Canary Islands, Gran canaria island26.00.1535215See
USAUSA Mexican American Mestizo0.1520553See
ZAFSouth African Black26.80.1409142See
CRICosta Rica Amerindians (G)27.80.1390125See
INDIndia Kerala Malayalam speaking24.40.1290356See
SAUSaudi Arabia pop 6 (G)0.121528927See
MARMorocco Atlantic Coast Chaouya0.121098See
MARMorocco Settat Chaouya24.20.121098See
USAUSA Arizona Gila River Pima0.12083000See
POLPoland BMR23.10.119623595See
INDIndia Karnataka Kannada Speaking22.40.1150174See
USAUSA San Francisco Caucasian0.1020220See
INDIndia Andhra Pradesh Telugu Speaking18.30.0995186See
ZAFSouth African Indian population16.00.090050See
ZAFSouth African Mixed ancestry18.00.090050See
ENGEngland Blood Donors of Mixed Ethnicity16.80.0857519See
VNMVietnam Kinh10.00.0495101See
HKGHong Kong Chinese HKBMDR HLA 11 loci7.70.04015266See
CHNChina Jingpo Minority1.90.0100105See
INDIndia New Delhi0.009071See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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