Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 32 time(s) and present in 32 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ZAFSouth African Black32.40.1690142See
SAUSaudi Arabia pop 6 (G)0.166728927See
INDIndia Andhra Pradesh Telugu Speaking29.60.1505186See
ZAFSouth African Indian population28.00.140050See
ZAFSouth African Mixed ancestry22.00.120050See
POLPoland BMR22.40.118123595See
BRABrazil Barra Mansa Rio State Black0.107173See
BRABrazil Rio de Janeiro Parda0.1065170See
INDIndia Karnataka Kannada Speaking21.30.1060174See
RUSRussia Belgorod region19.00.1013153See
INDIndia Kerala Malayalam speaking19.40.1010356See
ENGEngland Blood Donors of Mixed Ethnicity18.60.1002519See
ESPSpain, Canary Islands, Gran canaria island17.70.0954215See
CRICosta Rica Central Valley Mestizo (G)17.70.0910221See
CRICosta Rica African -Caribbean (G)16.60.0830102See
BRABrazil Rio de Janeiro Caucasian0.0817521See
BRABrazil Rio de Janeiro Black0.072968See
RUSRussian Federation Vologda Region14.30.0714119See
BRABrazil Barra Mansa Rio State Caucasian0.0664405See
CHNChina Zhejiang Han0.06521734See
USAUSA San Francisco Caucasian0.0560220See
CRICosta Rica Guanacaste Mestizo (G)10.00.0500110See
NICNicaragua Mestizo (G)8.40.0420155See
CRICosta Rica Amerindians (G)5.80.0290125See
HKGHong Kong Chinese HKBMDR HLA 11 loci5.30.02695266See
VNMVietnam Kinh4.00.0198101See
CHNChina Jingpo Minority1.90.0100105See
RUSRussia Bashkortostan, Bashkirs0.80.0083120See
MEXMexico Hidalgo Mezquital Valley/ Otomi1.40.006972See
RUSRussia Nizhny Novgorod, Russians1.30.00661510See
RUSRussia Bashkortostan, Tatars0.50.0026192See
USAUSA Arizona Gila River Pima0.00103000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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