Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 46 time(s) and present in 46 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
USAUSA Arizona Gila River Pima0.25063000See
TWNTaiwan Puyuma46.00.250050See
RUSRussia Tundra Nentsi NA-DHS_1 (G)40.00.200016See
CHNChina Jingpo Minority31.70.1730105See
TWNTaiwan Tao30.00.160050See
CHNChina Yunnan Province Lisu0.1510111See
HKGHong Kong Chinese HKBMDR HLA 11 loci24.50.13125266See
VNMVietnam Kinh24.00.1287101See
MEXMexico Hidalgo Mezquital Valley/ Otomi23.60.125072See
CHNChina Qinghai Province Hui0.1050110See
CHNChina Yunnan Province Nu0.1020107See
CHNChina North Han0.0900105See
TWNTaiwan Paiwan15.70.088051See
CHNChina Guangdong Province Meizhou Han0.0810100See
CHNChina Zhejiang Han0.07931734See
CHNChina Inner Mongolia Region0.0780102See
BOLBolivia/Peru Quechua NA-DHS_12 (G)14.30.071421See
TWNTaiwan Rukai14.00.070050See
CHNChina Tibet Region Tibetan0.0630158See
BOLBolivia/Chile Aymara NA-DHS_13 (G)10.00.050020See
USAUSA Mexican American Mestizo0.0430553See
ZAFSouth African Mixed ancestry6.00.040050See
COLColombia Inga NA-DHS_11 (G)6.70.033316See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
ZAFSouth African Indian population4.00.020050See
NICNicaragua Mestizo (G)3.80.0190155See
INDIndia Karnataka Kannada Speaking3.40.0170174See
RUSRussia Bashkortostan, Tatars3.10.0156192See
INDIndia Kerala Malayalam speaking2.30.0130356See
INDIndia Andhra Pradesh Telugu Speaking2.20.0108186See
CRICosta Rica Guanacaste Mestizo (G)1.80.0090110See
RUSRussia Bashkortostan, Bashkirs1.70.0083120See
CRICosta Rica Amerindians (G)1.60.0080125See
USAUSA Spain Ancestry0.0070279See
BRABrazil Rio de Janeiro Parda0.0046170See
BRABrazil Rio de Janeiro Caucasian0.0043521See
RUSRussian Federation Vologda Region0.80.0042119See
SAUSaudi Arabia pop 6 (G)0.004128927See
RUSRussia Nizhny Novgorod, Russians0.80.00401510See
ZAFSouth African Black0.70.0035142See
RUSRussia Belgorod region0.70.0033153See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
ENGEngland Blood Donors of Mixed Ethnicity0.20.0010519See
USAUSA African American pop 30.0010564See
POLPoland BMR0.10.000323595See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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