Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 155 time(s) and present in 142 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
RUSRussia Nenet Mixed0.298055See
MMRMyanmar Chin49.10.281855See
MMRMyanmar Kayin43.20.238644See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.218094See
MMRMyanmar Shan35.20.203754See
MMRMyanmar Kachin34.90.198463See
MMRMyanmar Rakhine37.50.187548See
VNMVietnam Hanoi0.180050See
MMRMyanmar Kayah27.30.163655See
INDIndia North Gujarat20.00.1429338See
MMRMyanmar Bamar26.10.141346See
RUSRussia Sakhalin Island Nivkhi0.132053See
ESPSpain Ibiza0.123088See
MYSMalaysia Negeri Sembilan Minangkabau0.120034See
MMRMyanmar Mon20.30.117264See
CHNChina Shandong Province Linqu County21.60.1145139See
CMRCameroon Ewondo0.105038See
CMRCameroon Bamileke 20.100035See
MYSMalaysia Perak Rawa0.090023See
MEXMexico Mexico City Mestizo pop 30.0890256See
THAThailand Northeast0.086066See
BRABrazil Parana Japanese16.00.0859192See
MEXMexico Mestizo pop 40.0853269See
THAThailand Northeast pop 20.0790400See
PERPeru Arequipa Mestizo15.50.0790168See
ESPSpain Minorca0.077094See
ESPSpain Majorca and Minorca0.077090See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.073096See
ITAItaly Sardinia pop30.0700100See
PRTPortugal North pop 20.06781801See
ITAItaly North pop 313.30.067097See
CHNChina Wuhan13.30.0670121See
MKDMacedonia MBMDR - Macedonian Muslims13.20.065876See
GNQEquatorial Guinea Bioko Island Bubi0.0650100See
GBRUnited Kingdom South West0.0644163See
USAUSA African American Bethesda11.70.0640187See
SCOScotland Orkney12.50.063099See
PRTAzores Terceira Island0.0620130See
ITAItaly Bergamo11.90.0610101See
ESPSpain Galicia and Murcia11.60.0597473See
ESPSpain, Castilla y Leon, Northwest,11.40.05961743See
CUBCuba Mixed pop 20.0590189See
CMRCameroon Uldeme0.057035See
MEXMexico Tapachula, Chiapas Mestizo Population11.10.055672See
ESPSpain Catalonia Girona0.052088See
GBRUnited Kingdom Orkney0.051188See
ESPSpain Majorca0.0510407See
VENVenezuela Zulia Maracaibo Mixed0.050020See
ENGEngland Liverpool9.60.04921343See
GRCGreece pop39.40.0481246See
JPNJapan pop 20.0450916See
BRABrazil Pernambuco Mixed0.0450101See
ESPSpain Andalusia Romani0.045099See
ARGArgentina Buenos Aires9.00.0450466See
FRAFrance Marseille8.90.04471000See
GBRUnited Kingdom Central0.0444135See
FRAFrance Rennes pop 48.80.04401000See
ENGEngland North West Mixed pop 28.70.0435379See
ENGEngland Manchester8.50.04341640See
ITAItaly North Pavia pop 30.0433685See
FRAFrance Lyon8.60.04314813See
ENGEngland Newcastle8.30.04242739See
FRAFrance Grenoble, Nantes and Rennes0.04206094See
MNGMongolia Tsaatan0.0420144See
INDIndia Kerala Hindu Ezhava0.042024See
IRNIran pop 40.0419855See
SRBSerbia pop 38.20.04091992See
ESPSpain Murcia8.00.0408173See
MNGMongolia Khalkha0.0400200See
RUSRussia Northwest pop 38.00.0400100See
ITAItaly East Sicily8.00.040050See
MNGMongolia Oold0.0390104See
BFABurkina Faso Mossi0.038053See
BRABrazil Curitiba-Parana Mixed0.0380264See
NORNorway pop 20.0380576See
WALWales pop 27.40.038039979See
SDNSudan East Rashaida7.40.037727See
FRAFrance Bordeaux7.50.0375990See
ARGArgentina La Plata8.00.0370100See
FRAFrance Grenoble7.30.03661000See
ENGEngland Leeds6.80.03465024See
GRCGreece pop 70.033711250See
GBRUnited Kingdom North0.0330330See
ENGEngland Lancaster6.50.0330545See
INDIndia Kerala Kuruma0.033015See
ITAItaly North Pavia0.031081See
JPNJapan Hyogo6.30.031032See
SRBSerbia Vojvodina6.00.0310400See
GBRUnited Kingdom East0.0307163See
SDNSudan Khartoum0.030698See
ENGEngland Sheffield6.00.03044755See
TTOTrinidad African0.030067See
ITAItaly Rome6.00.0300100See
ROMRomania pop 20.03006936See
VENVenezuela Colonia Tovar0.029186See
INDIndia North pop 20.029072See
LKASri Lanka Colombo Sinhalese0.0290101See
RUSRussia Moscow0.02902650See
SDNSudan Central Shaigiya Mixed5.60.028436See
RUSRussia Tatars0.0253355See
ESPSpain Gipuzkoa Basque0.0250100See
NORNorway ethnic Norwegians4.60.02354510See
FRAFrance Corsica Island0.0210100See
POLPoland pop 34.10.02052907See
DZAAlgeria pop 24.00.0202106See
POLPoland Lower Silesia Region4.10.0200123See
BFABurkina Faso Fulani0.020049See
VENVenezuela Caracas Mestizo0.020050See
PAKPakistan Mixed Pathan0.0200100See
POLPoland Wroclaw4.00.0200123See
MKDMacedonia MBMDR - Macedonian4.00.01991283See
SWESweden pop 43.70.0192966See
KURIraq Kurdistan Region3.80.0190209See
ROMRomania pop 33.60.01801469See
HRVCroatia pop 33.30.0167120See
ITAItaly South Campania Region3.30.01661089See
INDIndia Kerala Syrian Christian0.016031See
PAKPakistan Mixed Sindhi0.0150101See
PAKPakistan Brahui0.0150104See
JPNJapan Aichi2.80.014050See
ESPSpain Majorcans Jews0.0140103See
INDIndia Kerala Hindu Namboothiri0.013040See
POLPoland North2.50.012580See
INDIndia Kerala Hindu Nair0.012041See
SVNSlovenia pop 32.30.0120130See
BFABurkina Faso Rimaibe0.011047See
MKDMacedonia pop 40.0110216See
TTOTrinidad South Asian0.010087See
RUSRussia Arkhangelsk Pomor0.010063See
RUSRussia Murmansk Saomi Mixed0.010070See
ALBAlbania pop 21.90.0096432See
IRQIraq Erbil1.20.0064372See
SAUSaudi Arabia pop 40.80.0041499See
MKDMacedonia MBMDR - Albanian0.80.0039128See
NORNorway Sami0.0000200See
CMRCameroon Podokwo0.000043See
CZECzech Republic0.0000106See
PAKPakistan Kalash0.000069See
CHNChina North Han0.0000105See
INDIndia Kerala Hindu Pulaya0.000016See
INDIndia Kerala Paniya0.000010See
INDIndia Kerala Malapandaram0.000010See
INDIndia Kerala Adiya0.000021See
INDIndia Kerala Kurichiya0.000010See
INDIndia Kerala Kanikkar0.000022See
INDIndia Kerala Kattunaikka0.000017See
INDIndia Kerala Malabar Muslim0.000034See

See also higher resolution data of this allele

Allele  Number of Populations 
 C*08:03 122 
 C*08:02 218 
 C*08:01 202 
 C*08:06 47 
 C*08:13 10 
 C*08:03:01 12 
 C*08:07 17 
 C*08:11 14 
 C*08:12 16 
 C*08:05 38 
 C*08:01:01 46 
 C*08:08 27 
 C*08:09 12 
 C*08:02:01 27 
 C*08:10 13 
 C*08:04 78 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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