Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 
   

C*12

 
Allele reported 136 time(s) and present in 130 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
INDIndia Kerala Paniya0.300010See
ENGEngland London Ashkenazi Jews0.2320500See
IRQIraq Erbil42.70.2229372See
SDNSudan Central Shaigiya Mixed38.80.217736See
PAKPakistan Burusho0.209092See
ALBAlbanian Kosovo0.2000120See
PAKPakistan Mixed Sindhi0.1750101See
MMRMyanmar Chin25.50.172755See
IRNIran pop 40.1674855See
SRBSerbia Vojvodina30.00.1670400See
INDIndia Kerala Adiya0.167021See
KURIraq Kurdistan Region28.20.1650209See
VENVenezuela Caracas Mestizo0.160050See
TTOTrinidad South Asian0.160087See
POLPoland Wroclaw28.00.1510123See
GRCGreece pop 70.145111250See
GRCGreece pop326.80.1444246See
ESPSpain Majorcans Jews0.1430103See
MMRMyanmar Kachin25.40.142963See
MKDMacedonia MBMDR - Macedonian25.50.14221283See
POLPoland Lower Silesia Region26.80.1420123See
ITAItaly Rome25.00.1400100See
MKDMacedonia pop 40.1390216See
SRBSerbia pop 325.80.13521992See
CHNChina Shandong Province Linqu County25.20.1351139See
ROMRomania pop 324.20.13401469See
RUSRussia Moscow0.13402650See
ROMRomania pop 20.13006936See
SVNSlovenia pop 323.90.1280130See
MKDMacedonia0.1276286See
MKDMacedonia MBMDR - Albanian22.70.1250128See
POLPoland pop 324.90.12462907See
RUSRussia Tatars0.1197355See
MMRMyanmar Bamar21.70.119647See
POLPoland North22.50.119680See
RUSRussia Northwest pop 322.00.1150100See
MMRMyanmar Rakhine20.80.114648See
ITAItaly East Sicily22.00.110050See
PRTAzores Terceira Island0.1090130See
ITAItaly North Pavia pop 30.1070685See
HRVCroatia pop 320.80.1042120See
SRBSerbia0.1040386See
PAKPakistan Kalash0.101069See
CMRCameroon Uldeme0.100035See
ALBAlbania pop 219.10.0987432See
MKDMacedonia MBMDR - Macedonian Muslims19.70.098776See
ARGArgentina Buenos Aires17.80.0950466See
PAKPakistan Mixed Pathan0.0950100See
ESPSpain Murcia18.00.0944173See
VENVenezuela Colonia Tovar0.093086See
ALBAlbania0.0930160See
ESPSpain Majorca0.0920407See
BRABrazil Parana Japanese16.00.0912192See
INDIndia Kerala Hindu Namboothiri0.088040See
ESPSpain Galicia and Murcia16.70.0873473See
PAKPakistan Brahui0.0860104See
CZECzech Republic0.0850106See
ESPSpain Minorca0.085094See
INDIndia Kerala Hindu Nair0.085041See
MMRMyanmar Shan13.00.083354See
TUNTunisia16.00.0830100See
AUTAustria Cord Bloods0.08251368See
FRAFrance Marseille15.70.08011000See
MNGMongolia Khalkha0.0800200See
ESPSpain Ibiza0.079088See
MMRMyanmar Mon14.10.078164See
VENVenezuela Zulia Maracaibo Mixed0.075020See
LKASri Lanka Colombo Sinhalese0.0740101See
BRABrazil Curitiba-Parana Mixed0.0737264See
FRAFrance Grenoble14.40.07311000See
FRAFrance Lyon13.90.07064813See
MNGMongolia Tsaatan0.0690144See
SDNSudan South Nuba13.00.067246See
MNGMongolia Oold0.0670104See
FRAFrance Bordeaux12.60.0639990See
MMRMyanmar Kayah12.70.063655See
JPNJapan Hyogo12.50.063032See
SAUSaudi Arabia pop 411.80.0629499See
FRAFrance Grenoble, Nantes and Rennes0.06206094See
MEXMexico Mestizo pop 40.0615269See
CMRCameroon Podokwo0.058043See
SDNSudan East Rashaida11.10.057127See
GBRUnited Kingdom Orkney0.056888See
ENGEngland North West Mixed pop 210.80.0567379See
ITAItaly North Pavia0.056081See
PRTPortugal North pop 20.05361801See
ARGArgentina La Plata11.00.0520100See
FRAFrance Rennes pop 410.40.05191000See
MEXMexico Mexico City Mestizo pop 30.0510256See
BELBelgium10.10.051099See
DEUGermany Essen9.80.0490174See
CUBCuba Mixed pop 20.0480189See
GBRUnited Kingdom Central0.0444135See
GBRUnited Kingdom East0.0429163See
INDIndia North Gujarat8.60.0429338See
ENGEngland Manchester8.30.04241640See
MYSMalaysia Negeri Sembilan Minangkabau0.040034See
MYSMalaysia Perak Rawa0.040023See
GBRUnited Kingdom North0.0390330See
SWESweden pop 47.60.0388966See
ENGEngland Newcastle7.30.03712739See
ENGEngland Liverpool7.00.03561343See
NORNorway Sami0.0350200See
THAThailand Northeast0.033066See
ENGEngland Lancaster6.50.0330545See
WALWales pop 26.50.033039979See
ENGEngland Sheffield6.40.03254755See
ENGEngland Leeds6.30.03205024See
NORNorway ethnic Norwegians6.20.03164510See
NLDNetherlands UMCU4.70.031264See
NORNorway pop 20.0310576See
VNMVietnam Hanoi0.030050See
KORSouth Korea pop 10.0290324See
INDIndia Kerala Kattunaikka0.029017See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.027094See
CMRCameroon Ewondo0.026038See
BRABrazil Pernambuco Mixed0.0250101See
CHNChina Wuhan5.00.0250121See
GBRUnited Kingdom South West0.0245163See
INDIndia Kerala Kanikkar0.023022See
MMRMyanmar Kayin4.50.022744See
INDIndia Kerala Hindu Ezhava0.021024See
TTOTrinidad African0.020067See
PERPeru Arequipa Mestizo4.10.0200168See
NGANigeria3.50.0174258See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.016096See
INDIndia Kerala Syrian Christian0.016031See
CMRCameroon Bamileke 20.014035See
USAUSA African American Bethesda2.10.0110187See
RUSRussia Sakhalin Island Nivkhi0.009053See
CHNChina North Han0.0000105See
INDIndia Kerala Hindu Pulaya0.000016See
INDIndia Kerala Malabar Muslim0.000034See
INDIndia Kerala Malapandaram0.000010See
INDIndia Kerala Kurichiya0.000010See
INDIndia Kerala Kuruma0.000015See

Frequency data at lower resolution for this allele can be found in links below


Allele  Number of Populations 

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.




Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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