Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 30 time(s) and present in 27 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia Andhra Pradesh Telugu Speaking18.30.0968186See
ZAFSouth African Indian population12.00.070050See
INDIndia Kerala Malayalam speaking6.50.0320356See
CHNChina Zhejiang Han0.03091734See
HKGHong Kong Chinese HKBMDR HLA 11 loci6.10.03095266See
RUSRussian Federation Vologda Region5.00.0294119See
INDIndia Karnataka Kannada Speaking5.70.0290174See
NICNicaragua Mestizo (G)4.60.0230155See
RUSRussia Belgorod region4.60.0229153See
RUSRussia Nizhny Novgorod, Russians4.20.02121510See
USAUSA San Francisco Caucasian0.0210220See
ZAFSouth African Mixed ancestry4.00.020050See
RUSRussia Bashkortostan, Tatars3.10.0156192See
VNMVietnam Kinh3.00.0149101See
POLPoland BMR2.90.014523595See
BRABrazil Rio de Janeiro Caucasian0.0143521See
BRABrazil Barra Mansa Rio State Caucasian0.0122405See
ENGEngland Blood Donors of Mixed Ethnicity2.20.0106519See
ESPSpain, Canary Islands, Gran canaria island1.90.0093215See
CRICosta Rica Guanacaste Mestizo (G)1.80.0090110See
MARMorocco Settat Chaouya1.40.007098See
CRICosta Rica Central Valley Mestizo (G)1.40.0070221See
MARMorocco Atlantic Coast Chaouya0.007098See
SAUSaudi Arabia pop 51.30.0063158See
CRICosta Rica African -Caribbean (G)1.00.0050102See
BRABrazil Rio de Janeiro Parda0.0046170See
USAUSA Arizona Gila River Pima0.00173000See
CHNChina North Han0.0000105See
MARMorocco Nador Metalsa pop 20.000073See
KORSouth Korea pop 30.0000485See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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