Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 50 time(s) and present in 46 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
BRABrazil Barra Mansa Rio State Black0.102773See
CPVCape Verde Southeastern Islands0.089062See
ZAFSouth African Black11.30.0563142See
ESPSpain, Canary Islands, Gran canaria island10.70.0534215See
USAUSA Spain Ancestry0.0480279See
LBYLibya Cyrenaica0.0470118See
BRABrazil Barra Mansa Rio State Caucasian0.0444405See
USAUSA African American pop 30.0430564See
BRABrazil Rio de Janeiro Parda0.0414170See
BRABrazil Rio de Janeiro Caucasian0.0413521See
CRICosta Rica Guanacaste Mestizo (G)7.30.0410110See
MARMorocco Nador Metalsa0.040099See
USAUSA Mexican American Mestizo0.0370553See
SAUSaudi Arabia pop 55.70.0348158See
USAUSA Italy Ancestry0.0330273See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.30.031316See
CUBCuba Mixed0.030078See
MEXMexico Hidalgo Mezquital Valley/ Otomi5.60.027872See
CRICosta Rica Central Valley Mestizo (G)5.40.0270221See
MEXMexico Zapotec NA-DHS_7 (G)5.30.026320See
MARMorocco Settat Chaouya0.026098See
MARMorocco Atlantic Coast Chaouya0.025098See
CHLChile Huilliche NA-DHS_14 (G)5.00.025020See
CHLChile Easter Island0.024021See
GNBGuinea Bissau0.023065See
NICNicaragua Mestizo (G)4.60.0230155See
BRABrazil Rio de Janeiro Black0.022168See
RUSRussia Bashkortostan, Tatars4.20.0208192See
CRICosta Rica African -Caribbean (G)4.00.0200102See
RUSRussia Belgorod region3.90.0196153See
USAUSA Caucasian3.90.019661655See
CPVCape Verde Northwestern Islands0.016062See
RUSRussia Nizhny Novgorod, Russians3.10.01561510See
RUSRussia Bashkortostan, Bashkirs2.50.0125120See
USAUSA San Francisco Caucasian0.0110220See
RUSRussian Federation Vologda Region0.80.0084119See
POLPoland BMR1.60.008223595See
NIRIreland Northern1.60.00801000See
ENGEngland North West1.30.0070298See
CHNChina Inner Mongolia Autonomous Region Northeast0.80.0050496See
USAUSA Arizona Gila River Pima0.00093000See
CHNChina Zhejiang Han0.00061734See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.00.00015266See
KORSouth Korea pop 30.0000485See
CHNChina Han Guandong Province0.0000208See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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