Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 51 time(s) and present in 50 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ENGEngland Blood Donors of Mixed Ethnicity37.40.2062519See
ZAFSouth Africa Caucasians0.2000102See
USAUSA San Francisco Caucasian0.1600220See
INDIndia Karnataka Kannada Speaking30.50.1580174See
INDIndia Andhra Pradesh Telugu Speaking28.50.1479186See
USAUSA Eastern European0.1420558See
POLPoland BMR25.60.137223595See
MARMorocco Nador Metalsa pop 20.137073See
ZAFSouth African Indian population24.00.130050See
MARMorocco Atlantic Coast Chaouya0.128098See
MARMorocco Settat Chaouya25.60.128098See
ZAFSouth African Mixed ancestry24.00.120050See
BRABrazil Barra Mansa Rio State Caucasian0.1173405See
MNGMongolia Buryat0.1140141See
RUSRussian Federation Vologda Region20.20.1050119See
ESPSpain, Canary Islands, Gran canaria island20.00.1047215See
BRABrazil Rio de Janeiro Caucasian0.0988521See
RUSRussia Belgorod region19.00.0948153See
GRCGreece Athens18.70.09331888See
INDIndia Kerala Malayalam speaking16.30.0857356See
BRABrazil Barra Mansa Rio State Black0.082273See
BRABrazil Rio de Janeiro Parda0.0794170See
CRICosta Rica Central Valley Mestizo (G)15.30.0790221See
SAUSaudi Arabia pop 6 (G)0.071228927See
CHNChina North Han0.0710105See
MEXMexico Guadalajara Mestizo pop 20.0680103See
MEXMexico Hidalgo Mezquital Valley/ Otomi8.30.055672See
BRABrazil Rio de Janeiro Black0.051568See
CPVCape Verde Northwestern Islands0.048062See
CPVCape Verde Southeastern Islands0.048062See
GNBGuinea Bissau0.046065See
CRICosta Rica Guanacaste Mestizo (G)9.20.0460110See
CRICosta Rica African -Caribbean (G)8.80.0440102See
USAUSA African American pop 30.0440564See
NICNicaragua Mestizo (G)5.80.0290155See
ZAFSouth African Black5.60.0282142See
CRICosta Rica Amerindians (G)4.80.0240125See
CHNChina Tibet Region Tibetan0.0220158See
IRNIran Baloch0.0170100See
CHNChina Zhejiang Han0.01531734See
VNMVietnam Kinh3.00.0149101See
CHNChina Jingpo Minority2.90.0145105See
HKGHong Kong Chinese HKBMDR HLA 11 loci2.00.01035266See
RUSRussia Bashkortostan, Bashkirs0.80.0083120See
RUSRussia Nizhny Novgorod, Russians1.00.00501510See
JPNJapan Okinawa Ryukyuan0.0040143See
RUSRussia Bashkortostan, Tatars0.50.0026192See
USAUSA Arizona Gila River Pima0.00093000See
KORSouth Korea pop 30.0000485See

See also higher resolution data of this allele

Allele  Number of Populations 
 A*01:01:01:01 21 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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