Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 310 time(s) and present in 214 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
VENVenezuela Zulia San Jose de Heras Mixed0.125020See
GHAGhana Accre Asutuare Akan0.1240429See
ZAFSouth Africa Tswana17.10.085041See
SDNSudan South Nuba15.20.079146See
CMRCameroon Uldeme0.071035See
CMRCameroon Podokwo0.070043See
USAUSA OPTN African American0.06001510See
TTOTrinidad African0.060067See
CMRCameroon Bamileke 20.057035See
TZATanzania Dodoma Kongwa0.0480212See
BRABrazil Rio Grande do Sul Black0.0440248See
CUBCuba Mixed pop 20.0400189See
MEXMexico Veracruz, Coatzacoalcos0.035755See
BRABrazil REDOME Bahia0.030747399See
MEXMexico Jalisco, Tonala0.028635See
SDNSudan Central Shaigiya Mixed5.60.028436See
BRABrazil Minas Gerais State Mixed4.80.02501000See
BRABrazil South Ribeirao Preto0.0250184See
BRABrazil REDOME Acre0.0250859See
BRABrazil Belem Mixed5.00.0250100See
GAZGaza Palestinians0.0240165See
MEXMexico Chihuahua, Ciudad Juarez0.0231106See
MEXMexico Guanajuato, Guanajuato city0.022722See
BRABrazil REDOME Sergipe0.02167321See
GBRUnited Kingdom North0.0215330See
BRABrazil REDOME Tocantins0.021220692See
BRABrazil REDOME Pernambuco0.021292332See
BRABrazil Para Cord Blood Unit4.20.0208841See
MEXMexico Nayarit, Tepic0.020697See
BRABrazil Piaui Mixed0.020021943See
MYSMalaysia Perak Rawa0.020023See
BRABrazil Pernambuco Mixed0.0200101See
BRABrazil REDOME Piaui0.018946140See
BRABrazil REDOME Espirito Santo0.018888485See
BRABrazil REDOME Maranhao0.018710180See
BRABrazil REDOME Rio de Janeiro0.0184139322See
BRABrazil REDOME Mato Grosso0.018334649See
BRABrazil REDOME Minas Gerais0.0180211275See
BRABrazil REDOME Paraiba0.017943868See
MEXMexico Veracruz, Cordoba0.017956See
BRABrazil South East Cord Blood0.017211409See
BRABrazil REDOME Alagoas0.017125349See
BRABrazil REDOME Rondonia0.017054396See
BRABrazil REDOME Roraima0.01684140See
MEXMexico Chihuahua Chihuahua City0.0168119See
MEXMexico Morelos Rural0.016730See
BRABrazil REDOME Goias0.016388574See
BRABrazil REDOME Mato Grosso do Sul0.016095667See
COLColombia Barranquilla0.0160188See
BRABrazil Parana Mixed race3.20.0160186See
BRABrazil Rio Grande do Norte Mestizo0.016012973See
GTMGuatemala, Guatemala City Mixed Ancestry3.20.0157127See
BRABrazil REDOME Ceara0.0156101217See
BRABrazil REDOME Federal District0.015329549See
BRABrazil REDOME Rio Grande do Norte0.015346603See
SDNSudan Khartoum0.015398See
MEXMexico Sonora Rural0.0152197See
PAKPakistan Baloch0.015066See
MEXMexico Tabasco Rural0.0141142See
PAKPakistan Brahui0.0140104See
BRABrazil REDOME Para0.013872637See
BRABrazil REDOME Sao Paulo0.0136800809See
CMRCameroon Ewondo0.013038See
SAUSaudi Arabia pop 20.0130383See
BRABrazil Para State1.30.01305000See
BRABrazil REDOME Amazonas0.012924129See
MEXMexico Morelos, Cuernavaca0.012282See
BRABrazil REDOME Amapa0.012017864See
BRABrazil Sao Paulo Bauru Mixed0.01203542See
MEXMexico Zacatecas, Zacatecas city0.011984See
VENVenezuela Colonia Tovar0.011686See
MEXMexico Coahuila, Torreon0.0113396See
MEXMexico Zacatecas Rural0.0112266See
MEXMexico Chihuahua Rural0.0105236See
MEXMexico Quintana Roo, Cancun0.010448See
MEXMexico Nuevo Leon Rural0.0102439See
BRABrazil Paraná Caucasian2.00.0101641See
IRQIraq Arabs2.00.0101149See
ITAItaly East Sicily2.00.010050See
SAUSaudi Arabia pop 41.80.0100499See
PAKPakistan Mixed Pathan0.0100100See
MEXMexico Michoacan, Morelia0.0099150See
MEXMexico Durango, Durango city0.0097153See
BRABrazil REDOME Parana0.0090341639See
SENSenegal Dakar1.80.0090112See
MARMorocco Casablanca0.0090100See
MARMorocco pop 20.0090110See
MEXMexico Veracruz, Veracruz city0.0087171See
ECUEcuador Coast Mixed Ancestry0.0084238See
MEXMexico Veracruz, Orizaba0.008360See
MEXMexico Veracruz Rural0.0083539See
MEXMexico Oaxaca Rural0.0082485See
AREUnited Arab Emirates pop 21.60.0080373See
USAUSA OPTN Hispanic0.00801580See
PRTAzores Terceira Island0.0080130See
RUSRussia Nenet Mixed0.008055See
MEXMexico Nayarit Rural0.007864See
BOLBolivia Quechua0.007269See
MEXMexico Michoacan Rural0.0072348See
BRABrazil Rio Grande do Sul Mixed0.0070324See
CUBCuba Mixed0.007078See
CZECzech Republic Kurd1.40.006874See
MEXMexico Coahuila, Saltillo0.006872See
MEXMexico Jalisco, Guadalajara city0.00671189See
CHESwitzerland Geneva pop 20.00671267See
BRABrazil Curitiba-Parana Mixed0.0062264See
BRABrazil Parana Afro Brazilian1.30.006077See
PAKPakistan Karachi Parsi0.006091See
BRABrazil Parana Cafuzo1.20.0060319See
ESPSpain Majorca0.0060407See
MEXMexico Mestizo pop 40.0056269See
RUSRussia Northwest pop 31.00.0050100See
MEXMexico Puebla Mestizo0.005099See
ARGArgentina Cuyo Region0.90.0050420See
ITAItaly Rome1.00.0050100See
BRABrazil Sao Paulo Mixed0.10.0050239See
PAKPakistan Mixed Sindhi0.0050101See
CHNChina Yunnan Province Han pop 20.0050129See
BRABrazil REDOME Rio Grande do Sul0.0049241329See
MEXMexico Zacatecas, Fresnillo0.0048103See
MEXMexico Coahuila Rural0.0046216See
MEXMexico Tlaxcala Rural0.0042830See
MEXMexico Tamaulipas Rural0.0040125See
ENGEngland North West Mixed pop 20.80.0040379See
ISRIsrael Moroccan Jews0.0040113See
BRABrazil Parana Caucasian0.80.00402775See
FRAFrance Southeast0.80.0040130See
ESPSpain Murcia0.0040173See
MEXMexico Mexico City Mestizo0.0040121See
ITAItaly North Pavia pop 30.0039685See
BRABrazil REDOME Santa Catarina0.0039106673See
ECUEcuador Amazonia Mixed Ancestry0.003839See
ECUEcuador Mixed Ancestry0.00381173See
GBRUnited Kingdom Central0.0038135See
MEXMexico Guerrero state0.0035144See
MEXMexico Jalisco Rural0.0034585See
MEXMexico Puebla, Puebla city0.00331994See
MEXMexico Oaxaca, Oaxaca city0.0033151See
MEXMexico Guanajuato Rural0.0031162See
BRABrazil Rio Grande do Sul Caucasoid0.00304428See
PRTMadeira pop 20.0030173See
PRTPortugal Bragança0.0030301See
PRTPortugal Leiria0.00301847See
ARGArgentina Buenos Aires0.60.0030466See
PERPeru Arequipa Mestizo0.70.0030168See
MEXMexico Veracruz, Xalapa0.0027187See
MEXMexico Sinaloa Rural0.0027183See
MEXMexico Yucatan, Merida0.0026192See
BRABrazil Parana Japanese1.00.0026192See
FRAFrance Bordeaux0.50.0026990See
ECUEcuador Andes Mixed Ancestry0.0024824See
IRNIran pop 40.0023855See
ITAItaly South Campania Region0.40.00201089See
ARGArgentina Buenos Aires pop 24.40.00201216See
PRTPortugal Beja0.0020699See
ITAItaly North Pavia pop 20.40.00202416See
PRTMadeira pop 30.0020538See
PRTPortugal Santarem0.00203865See
PRTPortugal Setubal0.00205268See
SWESweden pop 40.30.0016966See
MEXMexico Durango Rural0.0015326See
PRTPortugal North pop 20.00151801See
INDIndia North Gujarat0.30.0015338See
ROMRomania pop 30.30.00141469See
MEXMexico Mexico City North0.0013751See
CHLChile Santiago0.0011920See
ITAItaly Lombardy0.30.0010674See
FRAFrance Marseille0.20.00101000See
FRAFrance Rennes pop 40.20.00101000See
RUSRussia Moscow Pop 20.20.00102000See
FRAFrance Lyon0.20.00104813See
WALWales pop 20.10.001039979See
RUSRussia Northwest pop 20.10.0010346See
PRTPortugal Viana do Castelo0.0010706See
PRTPortugal Vila Real0.00101167See
PRTPortugal Viseu0.00102915See
IRNIran Royan Cord Blood Bank0.30.001015600See
NORNorway pop 20.0010576See
PRTPortugal Aveiro0.00105933See
PRTPortugal Braga0.00101971See
PRTPortugal Lisbon0.001017420See
PRTPortugal Porto0.00107937See
PRTPortugal Coimbra0.00105057See
PRTPortugal Evora0.0010737See
PRTPortugal Faro0.00101242See
PRTPortugal Guarda0.0010797See
CHNChina Shandong Province0.10.00107418See
MYSMalaysia pop 30.00101445See
USAUSA OPTN Caucasian0.00108525See
ISRIsrael Jews pop 20.20.001023000See
PRTPortugal Center pop 20.0010562See
AUSAustralia West Caucasian0.20.0010891See
ESPSpain, Castilla y Leon, Northwest,0.10.00071743See
MEXMexico Puebla Rural0.0006833See
RUSRussia Northwest0.10.00051011See
ENGEngland Newcastle0.10.00052739See
FRAFrance Grenoble0.10.00051000See
SVKSlovakia pop 20.00044234See
NORNorway ethnic Norwegians0.10.00034510See
POLPoland pop 30.00.00022907See
GRCGreece pop 70.000211250See
IRLIreland South pop 20.000217624See
CHNChina Shanghai0.000126266See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.000094See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
CHNChina Yunnan Province Naxi0.0000118See
CHNChina Jiangsu Province0.000020248See
USAUSA OPTN Asian0.0000261See
PRTPortugal Portalegre0.00001254See
PRTPortugal Castelo Branco0.0000327See
FRAFrance Rennes pop 30.0000200See
MEXMexico Sinaloa Mestizo0.000056See
NORNorway Sami0.0000200See
BIHBosnia and Herzegovina0.0000134See
CHNChina Shaanxi Province Han0.000010000See
THAThailand pop 40.000016807See
RUSRussia South Ural Russian0.00.0000207See
RUSRussia South Ural Bashkir0.00.0000146See
RUSRussia South Ural Tatar0.00.0000135See
ARGArgentina Corrientes0.00.0000155See
HRVCroatia pop 20.0000100See
ENGEngland Leeds0.00.00005024See
MYSMalaysia pop 20.000062See
PRTPortugal South pop 20.00001021See
BRABrazil Parana Oriental0.00.000033See
CHNChina North Han0.0000105See
ISRIsrael Ashkenazi Jews pop 20.0000132See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
MEXMexico Nahuas0.000072See
MEXMexico Huasteca Region Teenek0.000055See
MEXMexico Mayan Pop 30.000066See
TURTurkey pop 50.0000142See
MKDMacedonia pop 40.0000216See
KORSouth Korea pop 10.0000324See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
ESPSpain Minorca0.000094See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
PRTPortugal North0.000046See
ARGArgentina La Plata0.00.0000100See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
VENVenezuela Caracas Mestizo0.000050See
TTOTrinidad South Asian0.000087See
GRCGreece North0.0000500See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
GBRUnited Kingdom Orkney0.000088See
GBRUnited Kingdom East0.0000163See
GBRUnited Kingdom South West0.0000163See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Mexico City West0.000033See
MEXMexico Mexico City East0.000079See
MEXMexico Mexico City Center0.0000152See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Colima Rural0.000043See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Baja California Rural0.000050See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Queretaro Rural0.000043See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See

See also higher resolution data of this allele

Allele  Number of Populations 
 B*42:01 171 
 B*42:01:01 16 
 B*42:02 129 
 B*42:04 13 
 B*42:05 17 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional