Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 84 time(s) and present in 64 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia Tamil Nadu Nadar0.156061See
CANCanada Chipewyan NA-DHS_2 (G)28.00.140025See
MARMorocco Nador Metalsa pop 20.095073See
USAUSA Arizona Gila River Pima0.09123000See
BGRBulgaria Romani0.091013See
CANCanada Cree NA-DHS_3 (G)16.70.083318See
POLPoland BMR14.80.076323595See
CANCanada Ojibwa NA-DHS_4 (G)13.30.066716See
RUSRussia Nizhny Novgorod, Russians13.00.06661510See
RUSRussia Belgorod region11.80.0621153See
USAUSA South Dakota Lakota Sioux0.0590302See
RUSRussian Federation Vologda Region10.10.0504119See
MARMorocco Settat Chaouya10.00.050098See
MARMorocco Atlantic Coast Chaouya0.050098See
AUSAustralia New South Wales Caucasian0.0500134See
BRABrazil Barra Mansa Rio State Caucasian0.0488405See
BRABrazil Rio de Janeiro Parda0.0463170See
USAUSA San Francisco Caucasian0.0460220See
BRABrazil Rio de Janeiro Caucasian0.0444521See
ENGEngland Blood Donors of Mixed Ethnicity8.60.0424519See
ZAFSouth African Mixed ancestry6.00.040050See
ESPSpain, Canary Islands, Gran canaria island7.00.0372215See
USAUSA New Mexico Canoncito Navajo0.037042See
COLColombia Wayuu NA-DHS_15 (G)7.10.035715See
ENGEngland North West7.00.0350298See
MEXMexico Chihuahua Tarahumara0.034044See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.70.033316See
BRABrazil Rio de Janeiro Black0.031268See
FRAFrance Southeast6.20.0310130See
COLColombia Arhuaco NA-DHS_16 (G)5.90.029417See
BRABrazil Barra Mansa Rio State Black0.028673See
USAUSA Mexican American Mestizo0.0270553See
USAUSA Italy Ancestry0.0270273See
ENGEngland London Ashkenazi Jews0.0250500See
MKDMacedonia pop 40.0250216See
ZAFSouth African Black4.90.0247142See
BOLBolivia/Peru Quechua NA-DHS_12 (G)4.80.023821See
SAUSaudi Arabia pop 54.40.0222158See
LBNLebanon Mixed0.021097See
BRABrazil Mixed0.0190108See
SAUSaudi Arabia pop 6 (G)0.017228927See
USAUSA African American pop 30.0170564See
CRICosta Rica Amerindians (G)3.20.0160125See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0160146See
NICNicaragua Mestizo (G)3.20.0160155See
CRICosta Rica African -Caribbean (G)3.00.0150102See
CHNChina Beijing0.015067See
CRICosta Rica Central Valley Mestizo (G)2.80.0140221See
RUSRussia Bashkortostan, Bashkirs2.50.0125120See
MEXMexico Oaxaca Mixtec0.0100103See
RUSRussia Tuva pop 20.0090169See
CRICosta Rica Guanacaste Mestizo (G)1.80.0090110See
INDIndia Karnataka Kannada Speaking1.10.0060174See
CHNChina Zhejiang Han0.00581734See
INDIndia Andhra Pradesh Telugu Speaking1.10.0054186See
IRNIran Baloch0.0050100See
CHNChina Qinghai Province Hui0.0050110See
CHNChina Guangzhou0.0050102See
USAUSA Spain Ancestry0.0040279See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.70.00345266See
INDIndia Kerala Malayalam speaking0.60.0030356See
RUSRussia Bashkortostan, Tatars0.50.0026192See
MEXMexico Oaxaca Zapotec0.000090See
PHLPhilippines Ivatan0.00.000050See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
KORSouth Korea pop 30.0000485See
CHNChina North Han0.0000105See
AUSAustralia Yuendumu Aborigine0.0000191See

See also higher resolution data of this allele

Allele  Number of Populations 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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