HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.

DRB1*16

Allele reported 371 time(s) and present in 360 population(s).

Population		Phenotype Frequency (%)	Allele Frequency (in_decimals)		Sample Size	IMGT/HLA¹ Database	Distribution²	Haplotype³ Association	Notesª
	Brazil Guarani M bya		0.3710		93	See
	United Arab Emirates pop 2	33.0	0.1810		373	See
	Macedonia MBMDR - Macedonian Muslims	31.6	0.1711		76	See
	Pakistan Brahui		0.1700		104	See
	Colombia Northwest Tule		0.1550		29	See
	Mexico Oaxaca, Oaxaca city		0.1490		151	See
	Macedonia MBMDR - Macedonian	27.5	0.1469		1283	See
	Macedonia		0.1469		286	See
	Albanian Kosovo		0.1375		120	See
	Greece pop 7		0.1337		11250	See
	Pakistan Baloch		0.1320		66	See
	Greece pop 5		0.1310		500	See
	Brazil Kaingang		0.1250		235	See
	Albania		0.1240		160	See
	Albania pop 2	23.6	0.1215		432	See
	Italy Sardinia		0.1210		86	See
	Czech Republic Romani pop 2	21.7	0.1196		46	See
	Croatia pop 2		0.1180		100	See
	Macedonia MBMDR - Albanian	20.3	0.1094		128	See
	Serbia pop 3	20.4	0.1087		1992	See
	Romania pop 3	20.3	0.1072		1469	See
	Serbia		0.1050		386	See
	Romania pop 2		0.1000		6936	See
	Greece North		0.1000		500	See
	Croatia pop 3	20.0	0.1000		120	See
	Bosnia and Herzegovina pop 2	19.2	0.1000		120	See
	Mexico Veracruz, Coatzacoalcos		0.0982		55	See
	Bosnia and Herzegovina		0.0970		134	See
	Mexico Puebla Rural		0.0965		833	See
	Mexico Mexico City South		0.0962		52	See
	Mexico Oaxaca Rural		0.0945		485	See
	Mexico Guerrero state		0.0903		144	See
	Mexico Mexico City Metropolitan Area Rural		0.0888		150	See
	Iraq Arabs	17.4	0.0872		149	See
	Argentina Corrientes	14.8	0.0870		155	See
	Ukraine Khmelnytskyi		0.0870		138	See
	Mexico Puebla, Puebla city		0.0867		1994	See
	Serbia Vojvodina	15.5	0.0820		400	See
	Turkey Istanbul	15.6	0.0813		250	See
	Mexico Puebla Mestizo		0.0810		99	See
	Mexico Tlaxcala Rural		0.0795		830	See
	Belarus Gomel Region		0.0790		100	See
	Brazil Para Cord Blood Unit	13.3	0.0708		841	See
	Mexico Veracruz Rural		0.0702		539	See
	Turkey Ankara		0.0700		50	See
	Mexico San Luis Potosi Rural		0.0690		87	See
	Italy North Pavia pop 3		0.0683		685	See
	Italy North Pavia		0.0680		81	See
	Italy North Pavia pop 2	13.9	0.0680		2416	See
	Mexico Mexico City North		0.0677		751	See
	Belarus Brest Region		0.0670		105	See
	Mexico Queretaro, Queretaro city		0.0667		45	See
	Mexico Veracruz, Orizaba		0.0667		60	See
	Mexico Tlaxcala, Tlaxcala city		0.0663		181	See
	Brazil REDOME Amazonas		0.0656		24129	See
	Mexico Tamaulipas, Ciudad Victoria		0.0652		23	See
	Brazil REDOME Amapa		0.0647		17864	See
	Ecuador Amazonia Mixed Ancestry		0.0641		39	See
	Italy Lombardy	12.3	0.0640		674	See
	Brazil Para State	9.5	0.0627		5000	See
	Mexico Nuevo Leon Rural		0.0625		439	See
	Slovakia pop 2		0.0620		4234	See
	Spain Malaga Romani	12.0	0.0619		80	See
	Mexico Coahuila, Saltillo		0.0616		72	See
	Mexico Veracruz, Veracruz city		0.0610		171	See
	Brazil REDOME Para		0.0610		72637	See
	Argentina Kolla		0.0600		61	See
	Mexico Tamaulipas Rural		0.0595		125	See
	Ukraine Lvov		0.0590		102	See
	Armenia Shirak		0.0590		76	See
	Brazil REDOME Roraima		0.0585		4140	See
	Mexico Mexico City Center		0.0584		152	See
	Poland pop 3	11.6	0.0580		2907	See
	Mexico Colima Rural		0.0568		43	See
	Mexico Nayarit, Tepic		0.0567		97	See
	Mexico Tabasco, Villahermosa		0.0549		82	See
	Taiwan Chinese immigrants from South China		0.0540		172	See
	Slovakia		0.0540		146	See
	Mexico Mestizo pop 4		0.0539		269	See
	Mexico Veracruz, Xalapa		0.0535		187	See
	Russia South Ural Tatar	10.4	0.0520		135	See
	Mexico Durango, Durango city		0.0516		153	See
	Mexico Jalisco, Tlaquepaque		0.0513		39	See
	China Beijing and Guangzhou		0.0510		1592	See
	Mexico Jalisco, Zapopan		0.0506		168	See
	Mexico San Luis Potosi, San Luis Potosi city		0.0500		30	See
	Mexico Mexico City East		0.0500		79	See
	Brazil REDOME Maranhao		0.0500		10180	See
	Mexico mestizo pop 3		0.0497		201	See
	Mexico Chiapas Rural		0.0496		121	See
	Brazil REDOME Piaui		0.0488		46140	See
	Mexico Tapachula, Chiapas Mestizo Population	9.7	0.0486		72	See
	Brazil Piaui Mixed		0.0480		21943	See
	Brazil REDOME Acre		0.0477		859	See
	Brazil Curitiba-Parana Mixed		0.0475		264	See
	Mexico Aguascalientes state		0.0474		95	See
	Thailand pop 4		0.0470		16807	See
	Brazil North East Mixed		0.0470		205	See
	Italy pop 2		0.0470		53	See
	Switzerland Luzern		0.0469		1553	See
	Mexico Nayarit Rural		0.0469		64	See
	Italy pop 6	9.2	0.0462		184	See
	Mexico Mexico City Mestizo		0.0460		121	See
	Russia Moscow		0.0460		2650	See
	Ecuador Mixed Ancestry		0.0452		1173	See
	Russia Moscow Pop 2	8.8	0.0450		2000	See
	Italy pop 4	8.8	0.0450		4575	See
	Colombia Antioquia Paisa		0.0450		100	See
	Belarus Vitebsk Region		0.0450		70	See
	Italy South Campania Region	8.8	0.0450		1089	See
	China Guangdong Province	8.7	0.0444		403	See
	Ecuador Andes Mixed Ancestry		0.0443		824	See
	Brazil Mato Grosso do Sul		0.0440		203	See
	Argentina Cuyo Region	8.6	0.0440		420	See
	Mexico Jalisco, Guadalajara city		0.0440		1189	See
	Iran		0.0430		58	See
	Russia Samara Region		0.0430		2500	See
	Brazil REDOME Tocantins		0.0430		20692	See
	Mexico Campeche Rural		0.0426		47	See
	Brazil REDOME Mato Grosso do Sul		0.0425		95667	See
	Saudi Arabia pop 4	7.6	0.0421		499	See
	Ecuador Coast Mixed Ancestry		0.0420		238	See
	Mexico Chihuahua, Ciudad Juarez		0.0417		106	See
	Brazil REDOME Ceara		0.0413		101217	See
	Brazil Rio Grande do Sul Mixed		0.0410		324	See
	Brazil Sao Paulo Bauru Mixed		0.0410		3542	See
	Malaysia pop 2		0.0410		62	See
	Mexico Jalisco Rural		0.0410		585	See
	Mexico Colima, Colima city		0.0410		61	See
	Sudan Khartoum		0.0408		98	See
	Brazil REDOME Parana		0.0401		341639	See
	Brazil REDOME Espirito Santo		0.0401		88485	See
	Brazil Rio Grande do Sul Black		0.0400		248	See
	Vietnam Hanoi		0.0400		50	See
	Thailand pop 2		0.0400		124	See
	Mexico Baja California, Tijuana		0.0400		25	See
	Brazil REDOME Rondonia		0.0395		54396	See
	Brazil REDOME Sao Paulo		0.0391		800809	See
	Croatia Gorski Kotar Region		0.0390		63	See
	Taiwan Hakka pop 2		0.0390		714	See
	Taiwan Minnan pop 2		0.0390		7137	See
	Portugal Beja		0.0390		699	See
	Mexico Zacatecas Rural		0.0390		266	See
	Iran pop 4		0.0385		855	See
	Mexico Durango Rural		0.0382		326	See
	Mexico Nuevo Leon, Monterrey city		0.0376		226	See
	Brazil REDOME Mato Grosso		0.0375		34649	See
	Brazil REDOME Rio Grande do Sul		0.0372		241329	See
	Russia Northwest pop 2	7.2	0.0370		346	See
	Iran Royan Cord Blood Bank	7.3	0.0370		15600	See
	Malaysia pop 3		0.0370		1445	See
	Argentina Buenos Aires pop 2	7.2	0.0370		1216	See
	Brazil REDOME Santa Catarina		0.0365		106673	See
	Brazil REDOME Alagoas		0.0365		25349	See
	Brazil REDOME Paraiba		0.0364		43868	See
	Brazil Rio Grande do Norte Mestizo		0.0360		12973	See
	Russia Northwest	7.2	0.0360		1011	See
	Mexico Veracruz, Cordoba		0.0357		56	See
	Brazil REDOME Rio Grande do Norte		0.0356		46603	See
	Mexico Sonora, Hermosillo		0.0354		99	See
	Mexico Baja Californa, Mexicali		0.0350		100	See
	Brazil Rio Grande do Sul Caucasoid		0.0350		4428	See
	Brazil REDOME Federal District		0.0350		29549	See
	Iraq Erbil	7.0	0.0350		372	See
	Russia Northwest pop 3	7.0	0.0350		100	See
	France Southeast	6.9	0.0350		130	See
	Portugal Bragança		0.0350		301	See
	Portugal Faro		0.0350		1242	See
	Russia Smolensk		0.0350		156	See
	Brazil South East Cord Blood		0.0343		11409	See
	Mexico Sinaloa, Culiacán		0.0340		103	See
	Portugal Evora		0.0340		737	See
	Jamaica		0.0340		132	See
	South Africa Limpopo Venda		0.0340		117	See
	China Han	6.7	0.0340		314	See
	Russia South Ural Russian	6.8	0.0340		207	See
	Mexico Coahuila, Torreon		0.0338		396	See
	Mexico Guanajuato Rural		0.0337		162	See
	Mexico Chihuahua Chihuahua City		0.0336		119	See
	Mexico Morelos Rural		0.0333		30	See
	Czech Republic pop 3	6.7	0.0330		180	See
	Brazil Parana Caucasian	6.6	0.0330		2775	See
	Switzerland Lugano		0.0325		1169	See
	Russia Tatars		0.0323		355	See
	Mexico Guanajuato, Leon		0.0321		78	See
	Brazil Sao Paulo Mixed	6.3	0.0320		239	See
	Brazil REDOME Goias		0.0318		88574	See
	Mexico Tabasco Rural		0.0317		142	See
	Switzerland Sion		0.0316		832	See
	Myanmar Mon	6.3	0.0313		64	See
	Brazil REDOME Minas Gerais		0.0312		211275	See
	Brazil REDOME Rio de Janeiro		0.0311		139322	See
	Brazil REDOME Pernambuco		0.0310		92332	See
	Portugal Santarem		0.0310		3865	See
	Saudi Arabia pop 2		0.0310		383	See
	France Marseille	6.2	0.0307		1000	See
	Switzerland Lausanne		0.0305		993	See
	Brazil REDOME Sergipe		0.0305		7321	See
	Mexico Morelos, Cuernavaca		0.0305		82	See
	France Grenoble	6.0	0.0301		1000	See
	Switzerland Basel		0.0300		1888	See
	Switzerland Zurich		0.0300		4875	See
	Armenia Syunik		0.0300		117	See
	Brazil Minas Gerais State Mixed	5.8	0.0300		1000	See
	Brazil Parana Oriental	6.1	0.0300		33	See
	Mexico Zacatecas, Zacatecas city		0.0298		84	See
	France Lyon	5.8	0.0291		4813	See
	Azores		0.0290		1050	See
	Armenia living in Karabakh		0.0290		445	See
	Brazil REDOME Bahia		0.0287		47399	See
	Switzerland Aargau-Solothurn		0.0287		1838	See
	Mexico Michoacan Rural		0.0287		348	See
	Mexico Zacatecas, Fresnillo		0.0286		103	See
	France Bordeaux	5.7	0.0285		990	See
	Portugal Portalegre		0.0280		1254	See
	Russia Kostroma Region		0.0280		126	See
	Poland Lodz		0.0280		103	See
	France Rennes pop 4	5.6	0.0278		1000	See
	Portugal Setubal		0.0270		5268	See
	Portugal Leiria		0.0270		1847	See
	France Grenoble, Nantes and Rennes		0.0270		6094	See
	Brazil Parana Mixed race	5.4	0.0270		186	See
	USA Southeast African American	5.4	0.0270		112	See
	Turkey pop 2		0.0270		228	See
	Mexico Baja California, La Paz		0.0267		75	See
	Mexico Yucatan Rural		0.0261		132	See
	Portugal Center pop 2		0.0260		562	See
	Russia Arkhangelsk Pomor		0.0260		63	See
	Portugal Lisbon		0.0260		17420	See
	Iraq Kurdistan Region	5.3	0.0260		209	See
	China Shandong Province Linqu County	5.0	0.0253		139	See
	Portugal Braga		0.0250		1971	See
	Venezuela Zulia Maracaibo Mixed		0.0250		20	See
	Venezuela Zulia San Jose de Heras Mixed		0.0250		20	See
	Portugal Viana do Castelo		0.0250		706	See
	Switzerland Bern		0.0249		3545	See
	Mexico Hidalgo, Pachuca		0.0244		41	See
	Germany	4.8	0.0243		11407	See
	Portugal Coimbra		0.0240		5057	See
	Taiwan Chinese immigrants from Middle China		0.0240		211	See
	Portugal South pop 2		0.0240		1021	See
	Italy North pop 2	4.6	0.0240		2054	See
	Portugal Vila Real		0.0240		1167	See
	Portugal Porto		0.0240		7937	See
	China Shaanxi Province Han		0.0240		10000	See
	Russia South Ural Bashkir	4.8	0.0240		146	See
	Switzerland Geneva pop 2		0.0237		1267	See
	Taiwan Aborigine		0.0230		111	See
	Portugal Castelo Branco		0.0230		327	See
	Switzerland Graubunden		0.0229		759	See
	Mexico Guanajuato, Guanajuato city		0.0227		22	See
	Russia, South Ural, Chelyabinsk region, Nagaybaks	4.5	0.0220		112	See
	China Shandong Province	4.3	0.0220		7418	See
	Russia Mari		0.0220		202	See
	Brazil Parana Cafuzo	4.4	0.0220		319	See
	Italy Central		0.0220		380	See
	Switzerland St Gallen		0.0217		2113	See
	Spain, Castilla y Leon, Northwest,	4.0	0.0217		1743	See
	Armenia living in USA		0.0210		233	See
	Cuba Mixed pop 2		0.0210		189	See
	Mexico Chihuahua Rural		0.0209		236	See
	Mexico Quintana Roo, Cancun		0.0208		48	See
	Mexico Yucatan, Merida		0.0205		192	See
	Mexico Baja California Rural		0.0200		50	See
	Mexico Quintana Roo Rural		0.0200		50	See
	United Kingdom pop 2		0.0200		101	See
	Trinidad South Asian		0.0200		87	See
	Pakistan Mixed Pathan		0.0200		100	See
	Azores Terceira Island		0.0200		130	See
	Israel Jews pop 2	3.9	0.0200		23000	See
	Burkina Faso Mossi		0.0200		53	See
	Mexico Michoacan, Morelia		0.0199		150	See
	Russia North Ossetian	3.9	0.0197		127	See
	Spain Malaga	3.8	0.0191		160	See
	Russia Arkhangelsk		0.0190		81	See
	Portugal Guarda		0.0190		797	See
	Brazil Parana Afro Brazilian	3.9	0.0190		77	See
	Armenia Ghegharkunik		0.0190		242	See
	Armenia Yerevan		0.0190		445	See
	Portugal Viseu		0.0190		2915	See
	United Kingdom East		0.0189		163	See
	Mexico Chiapas, Tuxtla Gutierrez		0.0189		52	See
	Myanmar Shan	3.7	0.0185		54	See
	Mexico Sinaloa Mestizo		0.0180		56	See
	China Shanghai		0.0180		26266	See
	Mexico Sonora Rural		0.0178		197	See
	Spain Valencia	3.5	0.0176		577	See
	Mexico Sonora, Ciudad Obregón		0.0175		143	See
	Russia Vologda		0.0170		121	See
	Portugal Aveiro		0.0170		5933	See
	Pakistan Karachi Parsi		0.0170		91	See
	Georgia Kurds		0.0170		30	See
	Mexico Jalisco, Tlajomulco		0.0167		30	See
	Brazil South Ribeirao Preto		0.0160		184	See
	Portugal North pop 2		0.0155		1801	See
	England Lancaster	3.0	0.0151		545	See
	Brazil Southeast Campinas Mixed	3.0	0.0151		99	See
	Spain Northwest	3.0	0.0151		1818	See
	Spain North	3.0	0.0151		156	See
	China Jiangsu Province		0.0150		20248	See
	India Andhra Pradesh Sunni	0.8	0.0150		100	See
	Pakistan Mixed Sindhi		0.0150		101	See
	Sweden pop 4	2.9	0.0150		966	See
	United Kingdom Central		0.0150		135	See
	Armenia Lori		0.0150		102	See
	Mexico Mexico City West		0.0147		33	See
	Mexico Jalisco, Tonala		0.0143		35	See
	Mexico Coahuila Rural		0.0138		216	See
	Czech Republic Kurd	2.7	0.0135		74	See
	Spain Granada		0.0130		280	See
	Taiwan Chinese immigrants from North China		0.0130		152	See
	United Kingdom Orkney		0.0123		88	See
	Mexico Hidalgo Rural		0.0123		81	See
	England	2.4	0.0120		537	See
	Mexico Queretaro Rural		0.0116		43	See
	Mexico Veracruz, Poza Rica		0.0111		45	See
	Finland		0.0110		91	See
	Australia West Caucasian	2.1	0.0110		891	See
	South Korea pop 8		0.0110		7096	See
	Madeira pop 3		0.0110		538	See
	Mexico Sinaloa Rural		0.0109		183	See
	Myanmar Bamar	2.2	0.0109		46	See
	India North Gujarat	1.8	0.0105		338	See
	Myanmar Rakhine	2.1	0.0104		48	See
	Armenia living in Lebanon		0.0100		368	See
	Trinidad African		0.0100		67	See
	Bangladesh Dhaka Bangalee		0.0100		141	See
	Venezuela Valencia and Maracaibo Caracus Mixed		0.0100		96	See
	Philippines National Capital Region		0.0100		51	See
	Sri Lanka Colombo Sinhalese		0.0090		101	See
	Mexico Guadalajara Mestizo		0.0090		54	See
	Russia Nenet Mixed		0.0090		55	See
	Tanzania Dodoma Kongwa		0.0090		212	See
	Jordan		0.0080		15141	See
	Sweden pop 5		0.0080		1569	See
	Argentina La Plata	2.0	0.0080		100	See
	England Sheffield	1.6	0.0080		4755	See
	England Newcastle	1.6	0.0080		2739	See
	Ireland Wexford	1.5	0.0080		200	See
	India Bikaner Raikas	1.5	0.0080		143	See
	England North West Mixed pop 2	1.6	0.0079		379	See
	Sweden Stockholm	1.3	0.0070		1347	See
	England Manchester	1.2	0.0060		1640	See
	England Leeds	1.2	0.0060		5024	See
	Russia Murmansk Saomi Mixed		0.0060		70	See
	Wales pop 2	1.3	0.0060		39979	See
	Armenia living in Iran		0.0060		85	See
	India North pop 3		0.0051		587	See
	Wales	1.1	0.0050		1798	See
	India Uttar Pradesh		0.0050		202	See
	England Liverpool	0.9	0.0045		1343	See
	Norway ethnic Norwegians	0.8	0.0039		4510	See
	Ireland South pop 2		0.0032		17624	See
	United Kingdom South West		0.0031		163	See
	Ireland Donegal	0.5	0.0030		200	See
	Japan pop 10		0.0030		332	See
	France West Breton		0.0030		150	See
	Mozambique		0.0020		202	See
	United Kingdom North		0.0015		330	See
	Morocco pop 2		0.0000		110	See
	India Andhra Pradesh Brahmin	0.0	0.0000		98	See
	Burkina Faso Fulani		0.0000		49	See
	Burkina Faso Rimaibe		0.0000		47	See
	Spain Gipuzkoa Basque		0.0000		100	See
	Spain Catalonia Girona		0.0000		88	See
	Pakistan Kalash		0.0000		69	See
	Argentina Salta Wichi pop 2	0.0	0.0000		19	See
	Pakistan Burusho		0.0000		92	See
	India Bikaner Non-Raikas	0.0	0.0000		127	See
	Mexico Campeche, Campeche city		0.0000		34	See

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.