Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 278 time(s) and present in 242 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MKDMacedonia pop 10.1490158See
MKDMacedonia pop 30.1390172See
GRCGreece pop225.60.1370120See
GRCGreece pop 40.137098See
HRVCroatia Krk Island Dubasnica0.130023See
GRCGreece pop322.40.1190246See
GRCGreece pop 60.1157242See
GRCGreece pop 821.70.114583See
HRVCroatia Krk Island0.1130212See
ITAItaly Sardinia pop220.40.10501129See
MKDMacedonia pop 20.097080See
HRVCroatia pop 40.09414000See
DEUGermany DKMS - Greece minority0.09161894See
DEUGermany DKMS - Croatia minority0.09022057See
DEUGermany DKMS - Bosnia and Herzegovina minority0.08121028See
GRCGreece Crete0.0780135See
ISRIsrael Georgia Jews0.07074471See
GEOGeorgia Caucasus Tbilisi0.0672119See
DEUGermany DKMS - Romania minority0.06441234See
SAUSaudi Arabia11.80.060818See
TURTurkey pop 10.0600250See
ITAItaly Bergamo10.90.0540101See
ITAItaly North pop 310.30.052097See
POLPoland DKMS0.049820653See
ITAItaly pop 50.0490975See
BORBorneo Bandjarmasin0.047021See
ESPSpain Andalusia Romani0.046099See
IRNIran Baloch0.0450100See
GEOGeorgia Svaneti Region Svan0.044080See
DEUGermany DKMS - Turkey minority0.04344856See
IRNIran Kurd pop 20.042060See
IRNIran Saqqez-Baneh Kurds0.041760See
IRNIran Tabriz Azeris0.041297See
AREUnited Arab Emirates Abu Dhabi0.038552See
USAUSA Eastern European0.0380558See
DEUGermany DKMS - Italy minority0.03751159See
ARGArgentina Buenos Aires7.20.0360466See
HRVCroatia Krk Island Vrbnik0.036028See
CZECzech Republic NMDR0.03595099See
FRAFrance Southeast6.90.0350130See
ESPSpain Andalusia0.035099See
IRNIran Kurd0.0350100See
ITAItaly Rome6.00.0350100See
IRNIran Fars Parsi0.034073See
ISRIsrael Iraq Jews0.031813270See
PRTPortugal South0.031049See
DZAAlgeria pop 26.00.0304106See
TUNTunisia pop 20.0300111See
SAUSaudi Arabia pop 6 (G)0.029728927See
RUSRussia Karelia0.02911075See
ISRIsrael USSR Jews0.029145681See
USAUSA Caucasian Pittsburgh5.80.0290177See
COLColombia Barranquilla0.0290188See
SVNSlovenia pop 25.70.0289140See
USAUSA NMDP Middle Eastern or North Coast of Africa0.028270890See
ISRIsrael Kavkazi Jews0.02812840See
RUSRussia Northwest Slavic0.0280200See
MEXMexico Nahua/Aztec Santo Domingo Ocotitlan0.027473See
TUNTunisia Jerba Berber0.027055See
DEUGermany Essen5.20.0260174See
DEUGermany pop 80.026039689See
ISRIsrael Morocco Jews0.025936718See
CZECzech Republic pop 25.10.025899See
BRABrazil Paraná Caucasian5.10.0257641See
BRABrazil Mixed0.0250108See
DZAAlgeria Oran0.0250100See
POLPoland Wielkopolska Region0.025099See
DEUGermany DKMS - Portugal minority0.02471176See
DEUGermany DKMS - Austria minority0.02421698See
CZECzech Republic0.0240106See
USAUSA Caucasian Bethesda4.80.0240307See
CUBCuba Mixed0.023078See
FRAFrance French Bone Marrow Donor Registry0.022342623See
LBNLebanon pop 20.0220191See
DEUGermany pop 60.02168862See
DEUGermany DKMS - German donors0.02143456066See
IRNIran pop 20.0210120See
ITAItaly Central0.0210380See
BRABrazil South Caucasian0.020873See
BRABrazil Mato Grosso do Sul0.0200203See
ARMArmenia combined Regions0.0200100See
ISRIsrael Yemenite Jews0.020076See
ESPSpain Murcia0.0200173See
MARMorocco Souss Region0.020098See
PRTAzores Terceira Island0.0200130See
PRTPortugal Center0.020050See
DEUGermany DKMS - France minority0.01991406See
ISRIsrael Argentina Jews0.01964307See
CANCanada British Columbia Penutian0.019026See
PNGPapua New Guinea Lowland Roro0.019026See
USAUSA Caucasian pop 50.0190268See
TUNTunisia pop 30.0190104See
ISRIsrael YemenJews0.018815542See
USAUSA Philadelphia Caucasian2.80.0180141See
PNGPapua New Guinea Highland pop20.018028See
PRTAzores Central Islands0.018059See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,3.40.01724335See
PRTMadeira pop 20.0170173See
ISRIsrael Poland Jews0.016513871See
ISRIsrael Ashkenazi Jews pop 30.01624625See
ISRIsrael Moroccan Jews0.0160113See
ESPSpain Barcelona3.20.0160941See
USAUSA San Francisco Caucasian0.0160220See
ZAFSouth Africa Caucasians0.0160102See
STPSao Tome Island Angolar0.016032See
DEUGermany DKMS - Spain minority0.01581107See
ISRIsrael USA Jews0.01516058See
NICNicaragua Managua3.00.0150339See
ARGArgentina Rio Negro Mapuche0.015034See
IRNIran pop 30.0150100See
DEUGermany DKMS - Netherlands minority0.01491374See
CZECzech Republic Romani2.90.014634See
BOLBolivia Quechua0.014569See
USAUSA NMDP European Caucasian0.01431242890See
USAUSA NMDP Caribean Hispanic0.0142115374See
SCOScotland Orkney2.90.014099See
BRABrazil North East Mixed0.0140205See
ESPSpain Tenerife Island0.014083See
USAUSA San Antonio Caucasian0.0135222See
DEUGermany pop 32.70.0135111See
PRTPortugal Azores Terceira Island2.60.0132130See
PRTAzores Oriental Islands0.013043See
ISRIsrael Ashkenazi Jews0.013080See
CHNChina, Xinjiang Uyghur Autonomous Region Han2.50.012570See
BRABrazil Southeast Mixed Race2.40.012042See
RUSRussia Chuvash0.012082See
MNGMongolia Hoton0.012085See
ITAItaly North Pavia0.012081See
LBNLebanon Yuhmur0.012082See
MNGMongolia Tarialan Khoton0.012085See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.01203830See
DEUGermany DKMS - United Kingdom minority0.01201043See
CHLChile Santiago0.0111920See
ISRIsrael Ashkenazi Jews pop 20.0110132See
USAUSA NMDP Caribean Indian0.011014339See
RUSRussia Tuva pop 20.0110169See
NLDNetherlands Leiden0.01101305See
PRTPortugal North0.011046See
TUNTunisia Gabes0.010595See
USAUSA NMDP Hispanic South or Central American0.0105146714See
TUNTunisia Gabes Arab0.010096See
RUSRussia Transbaikal Territory Buryats2.00.0100150See
USAUSA Caucasian Houston2.00.0100194See
RUSRussia Tuva0.0100190See
MARMorocco Atlantic Coast Chaouya0.010098See
MARMorocco Settat Chaouya0.010098See
JORJordan Amman0.0100146See
FRAFrance West2.00.0100100See
FRAFrance Rennes0.0100200See
FRAFrance Rennes pop 30.0100200See
COLColombia North Wiwa El Encanto0.009652See
MEXMexico Mexico City Tlalpan1.80.0091330See
MEXMexico Highlands Mestizos1.90.0090160See
LBNLebanon Niha el Shouff0.009061See
USAUSA Mexican American Mestizo pop 30.0090116See
USAUSA NMDP American Indian South or Central America0.00905926See
USAUSA NMDP Alaska Native or Aleut0.00901376See
USAUSA San Diego1.60.0090496See
ISRIsrael Arab0.0090109See
USAUSA NMDP North American Amerindian0.008435791See
ISRIsrael Iran Jews0.00838153See
ENGEngland pop 61.70.0080177See
STPSao Tome Island Forro0.008066See
JPNJapan pop 61.60.0080129See
USAUSA Hispanic pop 20.00781999See
MEXMexico Tixcacaltuyub Maya0.007567See
USAUSA NMDP Mexican or Chicano0.0073261235See
USAUSA African American Bethesda1.40.0070187See
USAUSA Southern California Mestizo1.40.007073See
FINFinland pop20.0070150See
ISRIsrael Arab pop 20.006712301See
USAUSA Caucasian pop 40.00671070See
GAZGaza Palestinians0.0060165See
USAUSA Colorado Univ Cord Blood Bank African American0.0060261See
IRLIreland South1.20.0060250See
ISRIsrael Non Ashkenazi Jews0.006080See
CODCongo Kinshasa Bantu1.10.006090See
CAFCentral African Republic Aka Pygmy1.20.006093See
ISRIsrael Druze0.00575914See
ISRIsrael Iranian Jews0.0050101See
CHLChile Santiago Mixed1.00.005070See
CHNChina Xinjiang Province Uyghur0.005092See
BRABrazil Southeast Caucasian1.00.0050103See
CHNChina Beijing Shijiazhuang Tianjian Han0.0050618See
CHNChina Guangxi Region Maonan0.0050108See
USAUSA South Dakota Sioux0.0050101See
MARMorocco Nador Metalsa0.005099See
MEXMexico Guanajuato and Jalisco Mestizo1.00.0050101See
RUSRussia Bering Island Aleuts0.0048104See
COLColombia Bogotá Cord Blood0.80.00441463See
MEXMexico Mexico City Mestizo pop 20.0043234See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00401058See
ENGEngland Bedfordshire0.80.0040354See
INDIndia Lucknow0.80.0040123See
GTMGuatemala, Guatemala City Mixed Ancestry0.80.0039127See
MEXMexico Mexico City Mestizo population0.0035143See
RUSRussia Belgorod region0.70.0033153See
USAUSA African American pop 70.0030193See
SDNSudan Mixed0.50.0030200See
NZLNew Zealand Maori0.0030200See
BRABrazil Puyanawa0.70.0030150See
MYSMalaysia Peninsular Chinese0.50.0026194See
ISRIsrael Tunisia Jews0.00239070See
USAUSA South Texas Hispanic0.0020194See
USAUSA NMDP Southeast Asian0.002027978See
USAUSA NMDP African American pop 20.0020416581See
MYSMalaysia Peninsular Indian0.40.0018271See
USAUSA NMDP Caribean Black0.001833328See
USAUSA NMDP Hawaiian or other Pacific Islander0.001711499See
CHNChina Zhejiang Han pop 20.0012833See
USAUSA NMDP African0.001128557See
MYSMalaysia Peninsular Malay0.20.0011951See
DEUGermany DKMS - China minority0.00121282See
LKASri Lanka Colombo0.30.0010714See
USAUSA African American pop 40.00102411See
HKGHong Kong Chinese BMDR0.00077595See
HKGHong Kong Chinese cord blood registry0.00063892See
USAUSA NMDP South Asian Indian0.0006185391See
USAUSA NMDP Chinese0.000499672See
USAUSA NMDP Filipino0.000450614See
CHNChina Hubei Han0.10.00043732See
ISRIsrael Ethiopia Jews0.00035928See
CHNChina Jiangsu Han0.00033238See
INDIndia Tamil Nadu0.00032492See
USAUSA NMDP Japanese0.000324582See
USAUSA NMDP Vietnamese0.000343540See
USAUSA Asian pop 20.00031772See
ISRIsrael Libya Jews0.00013739See
USAUSA NMDP Korean0.000177584See
ISRIsrael Bukhara Jews0.00002317See
ISRIsrael Ethiopian Jews0.0000122See
ISRIsrael Libyan Jews0.0000119See
IRNIran Yazd Zoroastrian0.000065See
IRNIran Azeri0.0000100See
INDIndia Tamil Nadu Chennai0.00.0000137See
IDNIndonesia Java0.000058See
CHNChina Hong Kong and Singapore0.0000135See
CHNChina Beijing and Xian0.0000171See
CANCanada British Columbia Athabaskan0.000062See
BRABrazil Central Plateau Xavante0.000074See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BRABrazil Guarani Nandeva0.000086See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
ARGArgentina Gran Chaco Eastern Toba0.0000135See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
COLColombia Bogota and Medellin Mestizo0.000065See
CHNChina Urumqi Uyghur0.00.000057See
CHNChina Harbin Manchu0.0000172See
CHNChina Harbin Korean0.0000201See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
USAUSA Alaska Yupik0.0000252See
TWNTaiwan Aborigine pop 20.000048See
TUNTunisia Matmata Berber0.000081See
WSMSamoa West0.000022See
KORSouth Korea pop 20.00.0000207See
LBNLebanon Kafar Zubian0.000094See
JPNJapan Hyogo Osaka and Nagano0.0000195See
MNGMongolia Ulaanbaatar Khalkha0.000041See
MNGMongolia Khalkha pop 20.0000202See
PNGPapua New Guinea Trobriand Island0.000081See
PNGPapua New Guinea East New Britain Tolai0.000048See
PRYParaguay Lengua0.000017See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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