Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 
   

DRB1*16:02

 
Allele reported 364 time(s) and present in 304 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
COLColombia North Eastern Plains Sikuani0.389027See
BRABrazil Guarani M bya0.371093See
BRABrazil Guarani Kaiowa0.3390155See
COLColombia West Waunana0.333030See
COLColombia West Embera0.325020See
MEXMexico Oaxaca Mixe0.309055See
BRABrazil Central Plateau Xavante0.303074See
BRABrazil Guarani Nandeva0.296086See
PNGPapua New Guinea Lowland Wosera0.288079See
MYSMalaysia Sarawak Bau Bidayuh0.280025See
BRABrazil Terena47.50.271060See
MYSMalaysia Sarawak Bidayuh0.250050See
BRABrazil Ticuna0.245050See
COLColombia Jaidukama0.231039See
PNGPapua New Guinea Dorogori0.220059See
PNGPapua New Guinea Lowland Roro0.212026See
MYSMalaysia Jelebu Temuan0.208025See
CRICosta Rica and Panama Mestizo0.200056See
VNMVietnam HoaBinh Muong0.199083See
PNGPapua New Guinea Wonie0.196051See
USAUSA New Mexico Zuni0.190051See
MEXMexico Oaxaca Zapotec0.188090See
MEXMexico Oaxaca Mixtec0.1840103See
MEXMexico Mazatecan0.183089See
MEXMexico Mixtec0.180097See
ARGArgentina Chiriguano33.90.179054See
COLWayu from Guajira Peninsula (Colombia)0.177148See
ARGArgentina Mapuche0.163048See
PNGPapua New Guinea South Gidra0.1620192See
ARGArgentina Rio Negro Mapuche0.161034See
MYSMalaysia Pahang Semai29.00.158038See
CHNChina Southwest Dai0.1530124See
PNGPapua New Guinea Madang0.146065See
COLColombia Guajira Peninsula Wayuu0.143088See
THAThailand North Dai Lue0.141096See
PNGPapua New Guinea Ume0.133090See
PNGPapua New Guinea Iamega0.133079See
PNGPapua New Guinea Wuroi0.132034See
CHNChina Guangxi Region Maonan0.1300108See
BRABrazil Kaingang0.1250235See
MYSMalaysia Sarawak Iban0.118051See
USAUSA Arizona Pima pop20.118018See
USAUSA South Dakota Sioux0.1150101See
USAUSA New Mexico Canoncito Navajo0.113042See
PNGPapua New Guinea Rual0.110050See
PNGPapua New Guinea Wipim0.109055See
PNGPapua New Guinea Kapal0.108065See
PNGPapua New Guinea Podare0.105043See
PNGPapua New Guinea Kuru0.098046See
USAUSA Arizona Gila River Amerindian0.0920492See
PNGPapua New Guinea Abam0.087063See
MYSMalaysia Peninsular Chinese16.00.0851194See
MEXMexico Huasteca Region Teenek0.083055See
VENVenezuela Sierra de Perija Yucpa0.080073See
MYSMalaysia Patani16.00.080025See
ECUEcuador Cayapa0.0790183See
COLColombia East Amazon Region Nukak0.075020See
COLColombia West Cauca0.075020See
THAThailand Northeast pop 20.0750400See
BRABrazil East Amazon0.073041See
BORBorneo Bandjarmasin0.071021See
RUSRussia Siberia Chukotka Peninsula Eskimo0.070080See
BOLBolivia Aymara0.0690102See
MEXMexico Guanajuato and Jalisco Mestizo13.90.0690101See
PNGPapua New Guinea East New Britain Rabaul0.067060See
THAThailand Kamphaeng Phet0.067097See
THAThailand Northeast0.065066See
MEXMexico Mexico City Mestizo pop 20.0641234See
CHLChile Mapuches0.0630104See
CHNChina Hong Kong and Singapore0.0630135See
IRNIran Fars Parsi0.062073See
CZECzech Republic Gypsy11.80.060834See
IRNIran Baloch0.0600100See
PRYParaguay Lengua0.059017See
MYSMalaysia0.058074See
TWNTaiwan pop10.0580539See
TWNTaiwan Tzu Chi Cord Blood Bank0.0570710See
PERPeru Quechua0.057044See
MEXMexico Highlands Mestizos11.30.0560160See
HKGHong Kong Chinese cord blood registry0.05513892See
CHNChina Wuhan10.70.0540121See
HKGHong Kong Chinese BMDR0.05377595See
CHNChina Canton Han0.0530264See
MYSMalaysia Champa10.30.052029See
IDNIndonesia Moluccan Islands0.050024See
TWNTaiwan Han Chinese0.0480504See
MEXMexico Mayan pop 20.0460163See
STPSao Tome Island Forro0.045066See
CHNChina pop18.70.0450103See
THAThailand0.0450142See
USAUSA NMDP Chinese0.043599672See
PNGPapua New Guinea East New Britain Tolai0.043048See
USAUSA Mexican American Mestizo pop 30.0430116See
PNGPapua New Guinea Trobriand Island0.043081See
THAThailand Bangkok pop 30.0430187See
COLColombia Bogotá8.40.04271463See
USAUSA African American Bethesda8.40.0420187See
GRCGreece6.00.041048See
IDNIndonesia Nusa Tenggara Islands0.041049See
IRNIran Azeri0.0400100See
MYSMalaysia Peninsular Malay7.40.0379951See
RUSRussia Siberia Eskimo0.037070See
MYSMalaysia Kelantan7.10.036028See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.035057See
IRNIran Kurd0.0350100See
CHNChina Urumqi Han0.034059See
BRABrazil North East Mixed0.0330205See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.03101058See
JPNJapan Hyogo6.30.031032See
MEXMexico Mazahua0.030065See
PERPeru Lamas City Lama0.030083See
IDNIndonesia Java Western5.90.0300236See
USAUSA NMDP North American Amerindian0.029135791See
MKDMacedonia pop 10.0290158See
BRABrazil Southeast Caucasian5.80.0290103See
PNGPapua New Guinea Highland0.029094See
SGPSingapore Riau Malay0.0280132See
CHLChile Santiago0.0275920See
DEUGermany DKMS - China minority0.02741282See
GTMGuatemala Mayan0.0260132See
CHNChina Harbin Manchu0.0260172See
CHLChile Santiago Mixed5.00.025370See
COLColombia Northwest Choco0.025020See
RUSRussia Siberia Chukchi0.025071See
BRABrazil Mato Grosso do Sul0.0250203See
USAUSA NMDP Mexican or Chicano0.0247261235See
GRCGreece pop 84.80.024183See
BRABrazil Southeast Mulatto4.80.024042See
TWNTaiwan pop 20.0240364See
CHNChina Beijing Shijiazhuang Tianjian Han0.0240618See
USAUSA NMDP Vietnamese0.023543540See
CHNChina Beijing and Xian0.0230171See
ARGArgentina Gran Chaco Eastern Toba0.0230135See
USAUSA NMDP Hispanic South or Central American0.0220146714See
CHNChina Yunnan Bulang0.0220116See
ARGArgentina Chubut Tehuelche0.022023See
LBNLebanon Kafar Zubian0.022094See
COLColombia North Chimila Amerindians0.021247See
ISRIsrael Libyan Jews0.0210119See
USAUSA Hispanic pop 20.02101999See
BRABrazil South Caucasian0.020873See
USAUSA Southern California Mestizo4.10.020773See
GRCGreece pop 60.0207242See
RUSRussia Siberia Chukotka Peninsula Chukchi0.020059See
USAUSA Colorado Univ Cord Blood Bank Asian0.0200100See
CHNChina Harbin Manchu pop 20.020050See
USAUSA Asian pop 20.01951772See
PNGPapua New Guinea Woigi0.019026See
MYSMalaysia Mandailing3.70.019027See
USAUSA NMDP Southeast Asian0.018927978See
GRCGreece pop33.70.0186246See
BRABrazil (BrasilCord)0.01818874See
PNGPapua New Guinea Highland pop20.018028See
VNMVietnam Hanoi Kinh pop 20.0180170See
CHNChina Yunnan Province Naxi0.0170118See
COLColombia Amazon Region Coreguaje0.017030See
IDNIndonesia Java0.017058See
JPNJapan Hyogo Osaka and Nagano0.0170195See
GHAGhana Accre Asutuare Akan0.0170429See
CHNChina Jiangsu Han0.01623238See
GRCGreece pop23.30.0160120See
CHNChina Yunnan Province Han pop 20.0160129See
USAUSA African American pop 40.01542411See
USAUSA NMDP Caribean Black0.015033328See
KORSouth Korea pop 10.0150324See
USAUSA South Texas Hispanic0.0150194See
MKDMacedonia pop 30.0150172See
CHNChina Yunnan Province Han0.0150101See
CUBCuba Mixed0.015078See
ISRIsrael Tunisia Jews0.01469070See
JPNJapan Hokkaido Wajin2.80.014171See
KORSouth Korea pop 42.80.0141211See
RUSRussia Siberia Negidal0.014035See
USAUSA NMDP African American0.0138416581See
USAUSA NMDP African0.013228557See
DEUGermany DKMS - Greece minority0.01321894See
GNQEquatorial Guinea Bioko Island Bubi0.0130100See
KORSouth Korea pop 110.0130149See
RUSRussia Northwest Slavic0.0130200See
CHNChina Yunnan Hani0.0130150See
GEOGeorgia Svaneti Region Svan0.013080See
CHNChina Jiangsu Province Han0.0122334See
MKDMacedonia pop 20.012080See
USAUSA Colorado Univ Cord Blood Bank African American0.0120261See
AUSAustralia Kimberly Aborigine0.012041See
MEXMexico Nuevo Leon Mestizo2.50.012040See
COLColombia San Basilio de Palenque0.012042See
JPNJapan pop 62.30.0115129See
INDIndia North2.30.011585See
ISRIsrael Kavkazi Jews0.01122840See
ISRIsrael Druze0.01115914See
KORSouth Korea pop 100.01114128See
JPNJapan Aichi2.20.011050See
INDIndia Delhi0.0110112See
RUSRussia Tuva pop30.011044See
HRVCroatia pop 40.01014000See
ISRIsrael Iranian Jews0.0100101See
TUNTunisia pop 30.0100104See
TWNTaiwan Aborigine pop 20.010048See
ESPSpain Andalusia Gipsy0.010099See
USAUSA African American pop 70.0100193See
BRABrazil Mixed0.0100108See
DZAAlgeria Oran0.0100100See
MNGMongolia Khalkha pop 20.0100202See
MTQMartinique0.0100100See
ITAItaly North pop 32.10.010097See
PRTPortugal Center0.010050See
MYSMalaysia Sabah Dusun0.010048See
ARMArmenia combined Regions0.0100100See
AUSAustralia Cape York Peninsula Aborigine0.0100103See
VNMVietnam Hanoi Kinh0.0100103See
USAUSA NMDP Korean0.009977584See
USAUSA NMDP Caribean Hispanic0.0096115374See
ISRIsrael Libya Jews0.00963739See
FJIFiji Viti Levu Island0.009057See
JPNJapan pop 160.009018604See
JPNJapan Central0.0090371See
KORSouth Korea pop 60.0090800See
PRTAzores Central Islands0.009059See
ZWEZimbabwe Harare Shona0.0090230See
USAUSA NMDP Filipino0.008650614See
NCLNew Caledonia0.008065See
COLColombia Bogota and Medellin Mestizo0.008065See
IRNIran Yazd Zoroastrian0.008065See
ISRIsrael Ashkenazi Jews pop 20.0080132See
SDNSudan Mixed1.50.0080200See
NLDNetherlands UMCU1.60.007864See
ARGArgentina Buenos Aires1.40.0070466See
BOLBolivia Quechua0.007080See
SVNSlovenia pop 21.40.0070140See
CHNChina Harbin Korean0.0070201See
LKASri Lanka Colombo1.40.0070714See
DEUGermany DKMS - Turkey minority0.00704856See
USAUSA San Diego1.40.0070496See
USAUSA NMDP South Asian Indian0.0067185391See
USAUSA NMDP Japanese0.006724582See
DEUGermany DKMS - Croatia minority0.00662057See
USAUSA NMDP Middle Eastern or North Coast of Africa0.006670890See
JPNJapan pop 170.00653078See
ARGArgentina Rosario Toba1.20.006086See
ISRIsrael Non Ashkenazi Jews0.006080See
CODCongo Kinshasa Bantu1.10.006090See
JPNJapan pop 20.0060916See
JPNJapan Kyoto and Osaka0.0060165See
KORSouth Korea pop 30.0060485See
NICNicaragua Managua1.20.0060339See
TUNTunisia Ghannouch0.006082See
DEUGermany DKMS - Portugal minority0.00551176See
DEUGermany DKMS - Romania minority0.00531234See
ITAItaly pop 50.0050975See
DZAAlgeria0.005097See
USAUSA Philippines0.0050105See
JPNJapan pop 30.00501018See
JPNJapan pop 41.00.0050525See
BELBelgium1.00.005099See
MNGMongolia Khalkha0.0050200See
TUNTunisia1.00.0050100See
CHNChina Xinjiang Province Uyghur0.005092See
SVNSlovenia1.00.0050100See
ESPSpain Barcelona1.00.0050941See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00491028See
DEUGermany DKMS - Italy minority0.00481159See
JPNJapan South0.80.0040125See
DEUGermany DKMS - Spain minority0.00361107See
ZAFSouth Africa Worcester1.00.0030159See
NZLNew Zealand Maori0.0030200See
ZAFSouth Africa Black0.0030200See
USAUSA Caucasian Bethesda0.60.0030307See
GABGabon Haut-Ogooue Dienga0.0030167See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00303830See
ISRIsrael YemenJews0.002715542See
INDIndia Tamil Nadu0.00252492See
DEUGermany pop 80.002439689See
DEUGermany DKMS - Austria minority0.00241698See
RUSRussia Karelia0.00241075See
CZECzech Republic NMDR0.00235099See
USAUSA San Francisco Caucasian0.0020220See
USAUSA Eastern European0.0020558See
AUTAustria0.50.0020200See
RWARwanda0.0020280See
SAUSaudi Arabia Guraiat and Hail0.50.0020213See
IRLIreland South0.40.0020250See
RWARwanda Kigali Hutu and Tutsi0.0020281See
DEUGermany DKMS - Netherlands minority0.00181374See
DEUGermany pop 60.00178862See
ISRIsrael Arab0.001612301See
ISRIsrael Argentina Jews0.00154307See
USAUSA NMDP European Caucasian0.00151242890See
POLPoland DKMS0.001320653See
ISRIsrael Ashkenazi Jews0.00114625See
ISRIsrael USA Jews0.00116058See
ITAItaly Central0.0010380See
NLDNetherlands0.20.0010447See
ISRIsrael Poland Jews0.000913871See
ISRIsrael USSR Jews0.000945681See
ISRIsrael Iran Jews0.00098153See
DEUGermany DKMS - France minority0.00071406See
ISRIsrael Georgia Jews0.00064471See
ISRIsrael Morocco Jews0.000436718See
DEUGermany DKMS - United Kingdom minority0.00051043See
ISRIsrael Iraq Jews0.000213270See
ISRIsrael Ethiopia Jews0.00015928See
ISRIsrael Bukhara Jews0.00002317See
ISRIsrael Ethiopian Jews0.0000122See
ISRIsrael Yemenite Jews0.000076See
ISRIsrael Arab0.0000109See
WSMSamoa West0.000022See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Irkutsk Tofalar0.000043See
RUSRussia Siberia Kushun Buryat0.000025See
RUSRussia Siberia Khanty Mansi0.000068See
RUSRussia Siberia Ulchi0.000073See
RUSRussia Siberia Khabarovsk Evenki0.000025See
USAUSA Philadelphia Caucasian0.00.0000141See
STPSao Tome Island Angolar0.000032See
USAUSA Caucasian pop 40.00001070See
PHLPhilippines0.000034See
PRTAzores Oriental Islands0.000043See
CHNChina Urumqi Kazak0.000042See
CHNChina Urumqi Uyghur0.00.000057See
DNKDenmark0.000055See
MNGMongolia Hoton0.000085See
LBNLebanon Niha el Shouff0.000061See
LBNLebanon Yuhmur0.000082See
IDNIndonesia Singaporean0.000050See
WSMSamoa0.000029See
PNGPapua New Guinea Lowland0.000047See
JPNJapan Nagano0.00.000057See
ISRIsrael Moroccan Jews0.0000113See
PRYParaguay Aché0.000087See
JPNJapan0.000050See
DZAAlgeria pop 20.00.0000106See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
CZECzech Republic pop 20.00.000099See
GRCGreece pop 40.000098See
JPNJapan pop 110.00.000062See
INDIndia Tamil Nadu Chennai0.00.0000137See
FRAFrance Rennes pop 30.0000200See
ARGArgentina Salta Wichi0.000024See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
NLDNetherlands Leiden0.00001305See
ZAFSouth Africa Caucasians0.0000102See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
PRTPortugal North0.000046See
PRTPortugal South0.000049See
ESPSpain Murcia0.0000173See
ITAItaly Bergamo0.00.0000101See
USAUSA San Antonio Caucasian0.0000222See
ITAItaly Rome0.00.0000100See
KORSouth Korea pop 20.00.0000207See
FRAFrance West0.00.0000100See
USAUSA Caucasian Houston0.00.0000194See
USAUSA Caucasian Pittsburgh0.00.0000177See
CAFCentral African Republic Aka Pygmy0.00.000093See
MNGMongolia Oold0.0000104See
MNGMongolia Tsaatan0.0000144See
CZECzech Republic0.0000106See
RUSRussia Siberia Sulamai Ket0.000022See
RUSRussia Siberia Polygus Evenk0.000035See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See

Frequency data at lower resolution for this allele can be found in links below


Allele  Number of Populations 

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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