Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 418 time(s) and present in 411 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
TWNTaiwan Chinese immigrants from South China0.7200172See
BRABrazil Kaingang0.4960235See
MEXMexico San Luis Potosi Rural0.270187See
MEXMexico Jalisco, Tlaquepaque0.269239See
MEXMexico Mexico City South0.259652See
MEXMexico Mexico City West0.250033See
MEXMexico Tlaxcala, Tlaxcala city0.2265181See
CHLChile Huilliche0.225040See
NORNorway Sami0.2230200See
MEXMexico Hidalgo Rural0.222281See
MEXMexico Tlaxcala Rural0.2151830See
MEXMexico Mexico City North0.2118751See
MEXMexico Jalisco, Tlajomulco0.200030See
MEXMexico Puebla Rural0.1996833See
MEXMexico Morelos, Cuernavaca0.195182See
MEXMexico Coahuila Rural0.1950216See
SDNSudan South Nuba34.80.192546See
MEXMexico Puebla Mestizo0.192099See
PERPeru Arequipa Mestizo35.60.1880168See
MEXMexico Nuevo Leon, Monterrey city0.1858226See
MEXMexico Baja California Rural0.180050See
BFABurkina Faso Rimaibe0.180047See
MEXMexico Puebla, Puebla city0.17891994See
MEXMexico Nuevo Leon Rural0.1784439See
MEXMexico Mexico City East0.175079See
MEXMexico mestizo pop 30.1716201See
ARGArgentina Kolla0.170061See
MEXMexico Veracruz, Cordoba0.169656See
MEXMexico Aguascalientes state0.168495See
MEXMexico Veracruz, Veracruz city0.1657171See
MEXMexico Michoacan Rural0.1605348See
MEXMexico Coahuila, Torreon0.1600396See
MEXMexico Hidalgo, Pachuca0.158541See
MEXMexico Coahuila, Saltillo0.157572See
MEXMexico Chihuahua, Ciudad Juarez0.1574106See
MEXMexico Sonora, Hermosillo0.156699See
MEXMexico Zacatecas Rural0.1561266See
MEXMexico Veracruz, Poza Rica0.155645See
MEXMexico Veracruz, Xalapa0.1551187See
MEXMexico Guanajuato, Leon0.153878See
MEXMexico Mexico City Center0.1526152See
MEXMexico Zacatecas, Fresnillo0.1524103See
MEXMexico Guanajuato Rural0.1503162See
MEXMexico Oaxaca Rural0.1499485See
MEXMexico Zacatecas, Zacatecas city0.148884See
MEXMexico Veracruz Rural0.1479539See
MEXMexico Quintana Roo, Cancun0.145848See
CHLChile Easter Island0.143021See
MEXMexico Jalisco, Tonala0.142935See
ECUEcuador Amazonia Mixed Ancestry0.141039See
MEXMexico Baja California, Tijuana0.140025See
MEXMexico Oaxaca, Oaxaca city0.1391151See
MEXMexico Tamaulipas Rural0.1389125See
MEXMexico Michoacan, Morelia0.1358150See
INDIndia Tamil Nadu Dravidian0.1340156See
MEXMexico Veracruz, Orizaba0.133360See
MEXMexico San Luis Potosi, San Luis Potosi city0.133330See
MEXMexico Durango, Durango city0.1323153See
MEXMexico Jalisco, Guadalajara city0.13231189See
MEXMexico Chiapas Rural0.1322121See
ARGArgentina Salta Wichi pop 226.30.132019See
MEXMexico Mexico City Metropolitan Area Rural0.1316150See
BRABrazil Guarani M bya0.129093See
MEXMexico Guerrero state0.1285144See
JPNJapan pop 100.1270332See
MEXMexico Sonora Rural0.1269197See
MEXMexico Jalisco Rural0.1263585See
MEXMexico Chihuahua Chihuahua City0.1261119See
MEXMexico Jalisco, Zapopan0.1250168See
VENVenezuela Zulia Maracaibo Mixed0.125020See
MEXMexico Yucatan Rural0.1231132See
BFABurkina Faso Mossi0.120053See
MEXMexico Chihuahua Rural0.1172236See
MEXMexico Morelos Rural0.116730See
MEXMexico Queretaro Rural0.116343See
MEXMexico Baja Californa, Mexicali0.1150100See
COLColombia Antioquia Paisa0.1140100See
MEXMexico Guanajuato, Guanajuato city0.113622See
MEXMexico Nayarit, Tepic0.113497See
BRABrazil Para Cord Blood Unit21.40.1124841See
MEXMexico Mexico City Mestizo0.1120121See
BRABrazil REDOME Amazonas0.111824129See
MEXMexico Queretaro, Queretaro city0.111145See
INDIndia Northeast Mech0.111063See
JPNJapan pop 80.1100308See
MEXMexico Quintana Roo Rural0.110050See
BRABrazil REDOME Amapa0.109917864See
MEXMexico Tamaulipas, Ciudad Victoria0.108723See
MEXMexico Baja California, La Paz0.106775See
USAUSA OPTN Hispanic0.10301580See
MEXMexico Mestizo pop 40.1022269See
BRABrazil REDOME Para0.102072637See
MEXMexico Sonora, Ciudad Obregón0.1014143See
BFABurkina Faso Fulani0.100049See
MEXMexico Tabasco Rural0.0986142See
BRABrazil Rio Grande do Sul Black0.0980248See
TWNTaiwan Hakka pop 20.0980714See
KORSouth Korea pop 80.09807096See
BRABrazil Para State20.90.09775000See
MEXMexico Campeche Rural0.095747See
MEXMexico Nayarit Rural0.093864See
INDIndia Northeast Rajbanshi0.092098See
ARGArgentina Cuyo Region17.60.0920420See
CHNChina Han17.50.0917314See
TWNTaiwan Minnan pop 20.09107137See
VNMVietnam Hanoi0.090050See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.089096See
BRABrazil REDOME Roraima0.08894140See
MEXMexico Durango Rural0.0887326See
ECUEcuador Andes Mixed Ancestry0.0880824See
ECUEcuador Mixed Ancestry0.08781173See
SDNSudan Khartoum0.086798See
BRABrazil Curitiba-Parana Mixed0.0860264See
TWNTaiwan Chinese immigrants from Middle China0.0850211See
MEXMexico Tapachula, Chiapas Mestizo Population15.30.083372See
MEXMexico Guadalajara Mestizo0.083054See
GTMGuatemala, Guatemala City Mixed Ancestry15.80.0827127See
MEXMexico Sinaloa, Culiacán0.0825103See
MEXMexico Yucatan, Merida0.0821192See
CHNChina Shanghai0.081026266See
MEXMexico Tabasco, Villahermosa0.079382See
BRABrazil REDOME Maranhao0.078910180See
CHNChina Shandong Province Linqu County15.10.0785139See
CHNChina Beijing and Guangzhou0.07801592See
ARGArgentina Buenos Aires pop 214.80.07801216See
GHAGhana Accre Asutuare Akan0.0780429See
ARGArgentina Corrientes12.90.0770155See
INDIndia Northeast Lachung0.077058See
MEXMexico Sinaloa Rural0.0765183See
BRABrazil REDOME Piaui0.074046140See
USAUSA OPTN African American0.07401510See
CHNChina Jiangsu Province0.074020248See
RUSRussia Murmansk Saomi Mixed0.074070See
ECUEcuador Coast Mixed Ancestry0.0735238See
SDNSudan Central Shaigiya Mixed13.90.072136See
BRABrazil Piaui Mixed0.072021943See
MEXMexico Veracruz, Coatzacoalcos0.071455See
HRVCroatia Gorski Kotar Region0.071063See
MEXMexico Sinaloa Mestizo0.071056See
BRABrazil Rio Grande do Norte Mestizo0.070012973See
PAKPakistan Burusho0.070092See
BRABrazil Rio Grande do Sul Mixed0.0700324See
BRABrazil REDOME Rio Grande do Norte0.069546603See
BRABrazil REDOME Mato Grosso do Sul0.068795667See
BRABrazil REDOME Ceara0.0684101217See
BRABrazil REDOME Pernambuco0.067192332See
BRABrazil REDOME Paraiba0.067043868See
BRABrazil North East Mixed0.0670205See
BRABrazil Parana Mixed race13.40.0670186See
BRABrazil Mato Grosso do Sul0.0670203See
BRABrazil REDOME Acre0.0669859See
USAUSA OPTN Asian0.0660261See
BRABrazil REDOME Alagoas0.065925349See
BRABrazil REDOME Rondonia0.065854396See
BRABrazil REDOME Sergipe0.06587321See
BRABrazil REDOME Tocantins0.065420692See
ARGArgentina La Plata13.00.0650100See
BRABrazil REDOME Mato Grosso0.064434649See
BRABrazil Parana Cafuzo12.80.0640319See
BRABrazil REDOME Bahia0.063947399See
BRABrazil REDOME Parana0.0629341639See
BRABrazil REDOME Espirito Santo0.062888485See
BRABrazil REDOME Federal District0.061529549See
CHNChina Guangdong Province11.90.0613403See
BRABrazil South Ribeirao Preto0.0600184See
CHNChina Shandong Province11.60.06007418See
BRABrazil Rio Grande do Sul Caucasoid0.05904428See
BRABrazil REDOME Goias0.058488574See
BIHBosnia and Herzegovina pop 211.70.0583120See
CHNChina Shaanxi Province Han0.058010000See
USAUSA Southeast African American10.70.0580112See
BRABrazil REDOME Minas Gerais0.0577211275See
IRQIraq Arabs11.40.0571149See
PRTPortugal Viseu0.05702915See
BRABrazil REDOME Rio de Janeiro0.0565139322See
BRABrazil REDOME Rio Grande do Sul0.0562241329See
PRTPortugal Aveiro0.05605933See
BRABrazil REDOME Sao Paulo0.0558800809See
BRABrazil South East Cord Blood0.055511409See
RUSRussia Nenet Mixed0.055055See
BLRBelarus Vitebsk Region0.055070See
BRABrazil REDOME Santa Catarina0.0542106673See
RUSRussia Vologda0.0540121See
PRTPortugal Vila Real0.05401167See
SWESweden Stockholm10.40.05401347See
PRTPortugal Bragança0.0530301See
ESPSpain Majorca0.0520407See
BRABrazil Sao Paulo Mixed10.00.0520239See
PRTAzores Terceira Island0.0510130See
SWESweden pop 49.80.0502966See
VENVenezuela Zulia San Jose de Heras Mixed0.050020See
MEXMexico Colima, Colima city0.049261See
PHLPhilippines National Capital Region0.049051See
NORNorway pop 20.0490576See
PRTPortugal Leiria0.04801847See
BRABrazil Minas Gerais State Mixed9.50.04801000See
TWNTaiwan Chinese immigrants from North China0.0480152See
BRABrazil Parana Caucasian9.70.04802775See
MMRMyanmar Kachin9.50.047663See
PRTPortugal North pop 20.04721801See
BRABrazil Sao Paulo Bauru Mixed0.04703542See
SRBSerbia Vojvodina9.20.0460400See
PRTPortugal Guarda0.0460797See
MEXMexico Colima Rural0.045543See
RUSRussia Arkhangelsk Pomor0.045063See
PRTPortugal Porto0.04507937See
PRTPortugal Viana do Castelo0.0450706See
NORNorway ethnic Norwegians8.70.04444510See
MEXMexico Campeche, Campeche city0.044134See
SWESweden pop 50.04401569See
PRTPortugal Coimbra0.04405057See
PRTPortugal Braga0.04401971See
CHESwitzerland Sion0.0435832See
FRAFrance Bordeaux8.70.0433990See
RUSRussia South Ural Russian7.70.0430207See
CHESwitzerland Lausanne0.0421993See
THAThailand pop 40.042016807See
CUBCuba Mixed pop 20.0420189See
CHESwitzerland Luzern0.04101553See
GBRUnited Kingdom East0.0409163See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks8.00.0400112See
RUSRussia Kostroma Region0.0400126See
UKRUkraine Lvov0.0400102See
PRTPortugal Center pop 20.0400562See
FRAFrance South7.80.0397350See
CHESwitzerland Lugano0.03921169See
CHESwitzerland Geneva pop 20.03901267See
ESPSpain Northwest Lugo7.60.0387145See
CHESwitzerland Aargau-Solothurn0.03861838See
GBRUnited Kingdom North0.0382330See
ITAItaly pop 66.50.0380184See
PRTPortugal Santarem0.03803865See
ESPSpain Granada0.0380280See
FRAFrance Grenoble7.40.03781000See
SDNSudan East Rashaida7.40.037727See
MEXMexico Chiapas, Tuxtla Gutierrez0.037752See
GBRUnited Kingdom Central0.0376135See
FRAFrance Lyon7.50.03764813See
GBRUnited Kingdom Orkney0.036888See
ESPSpain Valencia7.10.0361577See
RUSRussia Arkhangelsk0.036081See
BLRBelarus Gomel Region0.0360100See
UKRUkraine Khmelnytskyi0.0360138See
PRTPortugal Lisbon0.036017420See
CHESwitzerland Zurich0.03604875See
TWNTaiwan Aborigine0.0360111See
ESPSpain Madrid7.00.0356504See
CHESwitzerland Bern0.03513545See
RUSRussia Northwest pop 37.00.0350100See
RUSRussia Moscow0.03502650See
PRTPortugal Castelo Branco0.0350327See
FRAFrance Grenoble, Nantes and Rennes0.03506094See
FRAFrance Southeast6.90.0350130See
RUSRussia Moscow Pop 27.00.03482000See
CHESwitzerland Basel0.03461888See
ENGEngland North West Mixed pop 26.90.0343379See
ITAItaly North Pavia pop 30.0342685See
PRTPortugal Setubal0.03405268See
PRTMadeira pop 30.0340538See
CODCongo Kinshasa expatriates living in Belgium6.80.034075See
AUSAustralia West Caucasian6.60.0340891See
PRTPortugal South pop 20.03401021See
CHESwitzerland St Gallen0.03352113See
RUSRussia Samara Region0.03302500See
POLPoland pop 36.60.03292907See
FRAFrance Rennes pop 46.50.03251000See
RUSRussia Tatars0.0323355See
ITAItaly North pop 26.30.03202054See
RUSRussia Smolensk0.0320156See
RUSRussia Northwest pop 26.10.0310346See
MARMorocco Souss Region0.031098See
USAUSA OPTN Caucasian0.03108525See
BRABrazil Southeast Campinas Mixed6.10.030999See
SVKSlovakia pop 20.03094234See
SRBSerbia pop 36.20.03091992See
RUSRussia South Ural Tatar5.90.0300135See
FRAFrance West Breton0.0300150See
BRABrazil Parana Oriental6.10.030033See
TURTurkey Ankara0.030050See
TTOTrinidad African0.030067See
RUSRussia Northwest6.10.03001011See
HRVCroatia pop 20.0290100See
MYSMalaysia pop 20.029062See
BLRBelarus Brest Region0.0290105See
PRTPortugal Beja0.0280699See
ITAItaly pop 20.028053See
CZECzech Republic pop 35.60.0280180See
ESPSpain, Castilla y Leon, Northwest,5.10.02741743See
CHESwitzerland Graubunden0.0272759See
RUSRussia South Ural Bashkir5.50.0270146See
PRTPortugal Faro0.02701242See
ITAItaly Lombardy5.50.0270674See
ESPSpain Northwest5.20.02631818See
BIHBosnia and Herzegovina0.0261134See
PRTPortugal Evora0.0260737See
BRABrazil Parana Afro Brazilian5.20.026077See
INDIndia Tamil Nadu Chennai5.10.0258137See
ITAItaly North Pavia pop 24.80.02502416See
GBRUnited Kingdom South West0.0249163See
FRAFrance Marseille4.90.02451000See
COLColombia Bogota and Medellin Mestizo0.024065See
IRNIran pop 40.0238855See
ENGEngland Leeds4.70.02375024See
RUSRussia North Ossetian4.70.0236127See
MKDMacedonia MBMDR - Albanian4.70.0234128See
ALBAlbania pop 24.40.0231432See
PRTPortugal Portalegre0.02301254See
ENGEngland Newcastle4.50.02272739See
ENGEngland Sheffield4.50.02274755See
ESPSpain Malaga4.40.0222160See
INDIndia sub-Himalayan West Bengal Kami4.40.0222158See
ESPSpain Minorca0.022094See
ITAItaly pop 44.40.02204575See
GRCGreece pop 50.0220500See
WALWales pop 24.40.022039979See
MKDMacedonia MBMDR - Macedonian4.40.02181283See
CZECzech Republic Kurd2.70.020374See
ENGEngland Liverpool4.00.02021343See
TURTurkey Istanbul4.00.0202250See
ROMRomania pop 20.02006936See
THAThailand pop 20.0200124See
PAKPakistan Mixed Sindhi0.0200101See
ITAItaly Central0.0200380See
ITAItaly South Campania Region3.90.01961089See
INDIndia North Gujarat3.90.0195338See
TZATanzania Dodoma Kongwa0.0190212See
POLPoland Lodz0.0190103See
ITAItaly North Pavia0.019081See
IRLIreland South pop 20.018817624See
ENGEngland Manchester3.60.01811640See
THAThailand Northeast0.018066See
ROMRomania pop 33.40.01781469See
KURIraq Kurdistan Region3.30.0170209See
ESPSpain Majorcans Jews0.0170103See
INDIndia Bikaner Non-Raikas3.40.0170127See
HRVCroatia pop 33.30.0167120See
INDIndia North pop 30.0162587See
IRQIraq Erbil3.20.0162372See
GRCGreece pop 70.016011250See
MYSMalaysia pop 30.01601445See
ESPSpain North3.00.0151156See
ENGEngland Lancaster3.00.0151545See
GBRUnited Kingdom pop 20.0150101See
PAKPakistan Mixed Pathan0.0150100See
GRCGreece North0.0150500See
ARMArmenia Lori0.0150102See
ARMArmenia Ghegharkunik0.0140242See
PAKPakistan Kalash0.014069See
ITAItaly Sardinia0.014086See
MARMorocco pop 20.0140110See
THAThailand Northeast pop 20.0140400See
ARMArmenia Shirak0.013076See
ARMArmenia living in USA0.0130233See
IRNIran Royan Cord Blood Bank2.70.013015600See
IRLIreland Donegal2.50.0130200See
ALBAlbanian Kosovo0.0125120See
ISRIsrael Jews pop 22.50.012023000See
ARMArmenia Yerevan0.0120445See
ARMArmenia living in Karabakh0.0110445See
GRCGreece Crete0.0110135See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.011094See
RUSRussia Mari0.0110202See
CZECzech Republic Romani pop 22.20.010946See
MMRMyanmar Rakhine2.10.010448See
INDIndia Northeast Rastogi0.0100196See
TTOTrinidad South Asian0.010087See
SAUSaudi Arabia pop 41.60.0093499See
MMRMyanmar Shan1.90.009354See
PAKPakistan Baloch0.009066See
SAUSaudi Arabia pop 20.0090383See
INDIndia Northeast Sunni0.0080188See
MMRMyanmar Mon1.60.007864See
ARMArmenia living in Lebanon0.0070368See
BGDBangladesh Dhaka Bangalee0.0070141See
MKDMacedonia MBMDR - Macedonian Muslims1.30.006676See
ESPSpain Malaga Romani1.30.006580See
PAKPakistan Karachi Parsi0.006091See
ITAItaly Sardinia pop21.10.00601129See
GABGabon Haut-Ogooue Dienga0.0060167See
MNGMongolia Tarialan Khoton0.006085See
AREUnited Arab Emirates pop 21.10.0060373See
ARMArmenia living in Iran0.006085See
INDIndia Northeast Shia0.0050190See
IRNIran Baloch0.0050100See
PAKPakistan Brahui0.0050104See
LKASri Lanka Colombo Sinhalese0.0050101See
INDIndia Andhra Pradesh Brahmin0.30.005098See
INDIndia Andhra Pradesh Sunni0.30.0050100See
ARMArmenia Syunik0.0040117See
INDIndia Bikaner Raikas0.70.0040143See
INDIndia Northeast Kayastha0.0030190See
IRLIreland Wexford0.50.0030200See
INDIndia Uttar Pradesh0.0030202See
INDIndia Northeast Vaish0.0030198See
TURTurkey pop 20.0020228See
MNGMongolia Ulaanbaatar Khalkha0.000041See
ESPSpain Ibiza0.000088See
ZAFSouth Africa Limpopo Venda0.0000117See
INDIndia Northeast Mathur0.0000155See
INDIndia New Delhi pop 20.0000102See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
MYSMalaysia Perak Rawa0.000023See

See also higher resolution data of this allele

Allele  Number of Populations 
 DRB1*08:04 240 
 DRB1*08:16 39 
 DRB1*08:24 23 
 DRB1*08:01:01 33 
 DRB1*08:09 101 
 DRB1*08:18 51 
 DRB1*08:02:01 63 
 DRB1*08:21 33 
 DRB1*08:11 76 
 DRB1*08:23 22 
 DRB1*08:26 12 
 DRB1*08:01 334 
 DRB1*08:13 48 
 DRB1*08:04:03 10 
 DRB1*08:20 34 
 DRB1*08:03 304 
 DRB1*08:19 47 
 DRB1*08:34 10 
 DRB1*08:06 116 
 DRB1*08:04:02 12 
 DRB1*08:15 38 
 DRB1*08:22 21 
 DRB1*08:27 11 
 DRB1*08:02 354 
 DRB1*08:04:01 57 
 DRB1*08:03:02 109 
 DRB1*08:10 85 
 DRB1*08:07 73 
 DRB1*08:08 56 
 DRB1*08:05 67 
 DRB1*08:12 51 
 DRB1*08:28 13 
 DRB1*08:17 43 
 DRB1*08:25 13 
 DRB1*08:14 42 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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