Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 397 time(s) and present in 370 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CMRCameroon Bamileke 20.186035See
ESPSpain Pas Valley0.141088See
ESPSpain Gipuzkoa Basque0.1300100See
ZAFSouth Africa Natal Zulu24.00.1250100See
ZAFSouth Africa Tswana24.40.122041See
NORNorway pop 20.1060576See
MEXMexico Queretaro Rural0.104743See
BFABurkina Faso Fulani0.102049See
MEXMexico Veracruz, Orizaba0.100060See
ESPSpain Catalonia Girona0.098088See
ESPSpain Ibiza0.098088See
TUNTunisia Ghannouch0.091082See
MEXMexico Veracruz, Coatzacoalcos0.089355See
SAUSaudi Arabia16.70.087318See
PRTMadeira pop 20.0870173See
MEXMexico Jalisco, Tonala0.085735See
CMRCameroon Bakola Pygmy16.00.083450See
MEXMexico Quintana Roo, Cancun0.083348See
ESPSpain Murcia0.0830173See
ESPSpain Sevilla15.50.0827278See
ESPSpain Minorca0.082094See
ESPSpain Arratia Valley Basque0.080083See
VNMVietnam Hanoi0.080050See
ARGArgentina Corrientes14.20.0770155See
ESPSpain North Cabuerniga0.077095See
GBRUnited Kingdom Orkney0.074388See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.073096See
CUBCuba Mixed pop 20.0720189See
MEXMexico Chihuahua Chihuahua City0.0714119See
FRAFrance Bordeaux14.00.0698990See
PRTPortugal Viana do Castelo0.0690706See
ESPSpain Andalusia0.069099See
BRABrazil Parana Cafuzo13.20.0660319See
ESPSpain Majorca0.0660407See
BRABrazil REDOME Acre0.0646859See
FRAFrance Lyon12.70.06424813See
ECUEcuador Amazonia Mixed Ancestry0.064139See
MEXMexico Jalisco, Tlaquepaque0.064139See
CUBCuba Mixed0.064078See
MEXMexico Mestizo pop 40.0632269See
MEXMexico Sinaloa, Culiacán0.0631103See
ESPSpain Majorca and Minorca0.063090See
ARGArgentina Buenos Aires11.80.0610466See
PRTPortugal Portalegre0.06101254See
CHLChile Santiago0.0603920See
COLColombia San Basilio de Palenque0.060042See
PRTPortugal Vila Real0.06001167See
FRAFrance Rennes pop 30.0600200See
SCOScotland Orkney11.00.060099See
ESPSpain North Cantabria0.060083See
FRAFrance Corsica Island0.0600100See
PRTPortugal Braga0.05901971See
PRTPortugal Faro0.05901242See
MEXMexico Guanajuato Rural0.0583162See
PRTMadeira pop 30.0580538See
PRTPortugal Santarem0.05703865See
PRTPortugal Setubal0.05705268See
BRABrazil Minas Gerais State Mixed11.30.05701000See
PRTPortugal Viseu0.05602915See
FRAFrance Marseille11.00.05561000See
FRAFrance Rennes pop 411.10.05551000See
GBRUnited Kingdom East0.0552163See
FRAFrance Southeast10.80.0550130See
BRABrazil Parana Mixed race10.70.0540186See
ENGEngland London Ashkenazi Jews0.0540500See
PRTPortugal Lisbon0.054017420See
PRTPortugal Porto0.05307937See
PRTPortugal Coimbra0.05305057See
PRTPortugal Bragança0.0530301See
BRABrazil Rio Grande do Norte Mestizo0.053012973See
GEOGeorgia Kurds0.053030See
MKDMacedonia MBMDR - Macedonian Muslims10.50.052676See
MEXMexico Zacatecas, Fresnillo0.0524103See
PRTPortugal North pop 20.05241801See
PRTPortugal Evora0.0520737See
PRTPortugal Beja0.0520699See
PRTPortugal Leiria0.05201847See
ENGEngland Liverpool10.10.05181343See
FRAFrance Grenoble, Nantes and Rennes0.05106094See
PRTPortugal Guarda0.0510797See
PRTPortugal Aveiro0.05105933See
MEXMexico Coahuila Rural0.0505216See
BRABrazil REDOME Rio Grande do Norte0.050446603See
BRABrazil REDOME Paraiba0.050243868See
MEXMexico Baja California Rural0.050050See
MEXMexico San Luis Potosi, San Luis Potosi city0.050030See
COLColombia Barranquilla0.0500188See
BRABrazil REDOME Goias0.049488574See
MEXMexico Colima, Colima city0.049261See
BRABrazil REDOME Federal District0.049129549See
BRABrazil Rio Grande do Sul Mixed0.0490324See
BRABrazil South Ribeirao Preto0.0490184See
TUNTunisia pop 30.0490104See
PRTPortugal Center pop 20.0490562See
BRABrazil REDOME Ceara0.0489101217See
BRABrazil REDOME Rio de Janeiro0.0487139322See
BRABrazil REDOME Minas Gerais0.0486211275See
FRAFrance Grenoble9.70.04841000See
BRABrazil REDOME Sergipe0.04817321See
MNGMongolia Tarialan Khoton0.048085See
MNGMongolia Hoton0.048085See
CUBCuba Mixed Race9.50.048042See
PRTPortugal South pop 20.04801021See
ENGEngland Manchester9.30.04761640See
BRABrazil REDOME Santa Catarina0.0476106673See
BRABrazil Paraná Caucasian9.20.0476641See
BRABrazil REDOME Tocantins0.047220692See
ENGEngland Newcastle9.20.04712739See
BRABrazil REDOME Alagoas0.046225349See
ENGEngland North West Mixed pop 29.20.0462379See
BRABrazil Rio Grande do Sul Black0.0460248See
BRABrazil Rio Grande do Sul Caucasoid0.04604428See
MEXMexico Durango Rural0.0459326See
BRABrazil REDOME Mato Grosso do Sul0.045595667See
MEXMexico Sinaloa Mestizo0.045056See
ARGArgentina Buenos Aires pop 28.60.04501216See
BRABrazil REDOME Rio Grande do Sul0.0448241329See
MEXMexico Veracruz, Cordoba0.044656See
BRABrazil REDOME Sao Paulo0.0444800809See
BRABrazil REDOME Pernambuco0.044192332See
IRLIreland South pop 20.044117624See
MEXMexico Campeche, Campeche city0.044134See
BRABrazil Piaui Mixed0.044021943See
BRABrazil REDOME Espirito Santo0.044088485See
ESPSpain Majorcans Jews0.0440103See
BRABrazil REDOME Mato Grosso0.043934649See
BRABrazil South East Cord Blood0.043911409See
BRABrazil REDOME Rondonia0.043854396See
BRABrazil REDOME Piaui0.043346140See
BRABrazil REDOME Maranhao0.043110180See
PRTPortugal Castelo Branco0.0430327See
WALWales pop 28.40.043039979See
PRTAzores Terceira Island0.0430130See
USAUSA OPTN Hispanic0.04301580See
ENGEngland Leeds8.40.04295024See
MEXMexico Campeche Rural0.042647See
SDNSudan Central Shaigiya Mixed8.30.042436See
MEXMexico Tabasco Rural0.0423142See
BRABrazil Sao Paulo Bauru Mixed0.04203542See
MEXMexico Chihuahua Rural0.0418236See
MEXMexico Guerrero state0.0417144See
BRABrazil REDOME Para0.041672637See
BRABrazil REDOME Parana0.0415341639See
ENGEngland Sheffield8.10.04134755See
GBRUnited Kingdom Central0.0412135See
MARMorocco pop 20.0410110See
ITAItaly pop 68.20.0408184See
MEXMexico Jalisco, Guadalajara city0.04061189See
BRABrazil REDOME Bahia0.040247399See
GBRUnited Kingdom pop 20.0400101See
BRABrazil Parana Caucasian8.00.04002775See
GRCGreece Crete0.0400135See
ITAItaly Rome8.00.0400100See
BRABrazil Sao Paulo Mixed0.80.0400239See
MEXMexico Coahuila, Torreon0.0400396See
MEXMexico Nuevo Leon, Monterrey city0.0398226See
ISRIsrael Jews pop 27.70.039023000See
USAUSA OPTN Caucasian0.03908525See
ARMArmenia Ghegharkunik0.0390242See
BRABrazil REDOME Roraima0.03824140See
ENGEngland Lancaster7.50.0382545See
INDIndia Jalpaiguri Toto7.50.038240See
BRABrazil REDOME Amazonas0.037724129See
BRABrazil REDOME Amapa0.037717864See
ARMArmenia Yerevan0.0370445See
ARGArgentina Cuyo Region7.20.0370420See
AUSAustralia West Caucasian7.30.0370891See
MEXMexico Tabasco, Villahermosa0.036682See
MEXMexico Michoacan, Morelia0.0364150See
GBRUnited Kingdom North0.0363330See
ISRIsrael Moroccan Jews0.0360113See
MEXMexico Jalisco, Zapopan0.0357168See
MEXMexico Baja Californa, Mexicali0.0350100See
MEXMexico Puebla Mestizo0.035099See
MEXMexico San Luis Potosi Rural0.034587See
CZECzech Republic Kurd6.80.033874See
ECUEcuador Coast Mixed Ancestry0.0336238See
MEXMexico Baja California, La Paz0.033375See
ITAItaly Lombardy6.40.0330674See
ITAItaly North Pavia pop 26.60.03302416See
ARMArmenia Shirak0.033076See
MEXMexico Sinaloa Rural0.0328183See
MEXMexico Mexico City Center0.0325152See
MEXMexico Chihuahua, Ciudad Juarez0.0324106See
SAUSaudi Arabia pop 46.40.0321499See
BRABrazil Parana Afro Brazilian6.50.032077See
COLColombia Wayu from Guajira Peninsula0.031348See
MEXMexico Mexico City Mestizo pop 30.0310256See
USAUSA OPTN African American0.03101510See
ITAItaly North Pavia0.031081See
MEXMexico Jalisco Rural0.0307585See
ARMArmenia Syunik0.0300117See
BRABrazil Pernambuco Mixed0.0300101See
MKDMacedonia pop 40.0300216See
TTOTrinidad African0.030067See
MYSMalaysia Negeri Sembilan Minangkabau0.030034See
IRQIraq Erbil5.60.0296372See
ITAItaly North Pavia pop 30.0290685See
ARMArmenia living in Iran0.029085See
ARGArgentina La Plata6.00.0290100See
CHNChina Yunnan Province Han pop 20.0290129See
GRCGreece pop35.70.0289246See
MEXMexico Chiapas Rural0.0289121See
ECUEcuador Mixed Ancestry0.02861173See
MEXMexico Chiapas, Tuxtla Gutierrez0.028352See
INDIndia North Gujarat5.60.0281338See
MEXMexico Zacatecas Rural0.0279266See
MEXMexico Coahuila, Saltillo0.027472See
MEXMexico Michoacan Rural0.0272348See
PERPeru Arequipa Mestizo5.40.0270168See
ITAItaly South Campania Region5.20.02631089See
ESPSpain Andalusia Romani0.026099See
ITAItaly Bergamo5.00.0260101See
NORNorway Sami0.0260200See
CMRCameroon Ewondo0.026038See
MEXMexico Durango, Durango city0.0258153See
MEXMexico Guanajuato, Leon0.025678See
MEXMexico Sonora, Hermosillo0.025399See
DZAAlgeria pop 25.00.0253106See
IRNIran pop 40.0252855See
MEXMexico Mexico City East0.025079See
IRNIran Royan Cord Blood Bank4.90.025015600See
MEXMexico Mexico City Mestizo0.0250121See
VENVenezuela Zulia Maracaibo Mixed0.025020See
MEXMexico Hidalgo, Pachuca0.024441See
MEXMexico Morelos, Cuernavaca0.024482See
ECUEcuador Andes Mixed Ancestry0.0243824See
GAZGaza Palestinians0.0240165See
KURIraq Kurdistan Region4.30.0240209See
MEXMexico Mestizo4.90.024041See
ISRIsrael Ashkenazi Jews pop 20.0240132See
INDIndia Kerala Hindu Nair0.024041See
MEXMexico Oaxaca Rural0.0236485See
MEXMexico Nayarit Rural0.023464See
MEXMexico Oaxaca, Oaxaca city0.0232151See
MEXMexico Veracruz Rural0.0231539See
SVNSlovenia pop 34.60.0230130See
GTMGuatemala Mayan0.0230132See
IRNIran pop 10.023064See
CMRCameroon Podokwo0.023043See
MEXMexico Guanajuato, Guanajuato city0.022722See
MEXMexico Queretaro, Queretaro city0.022245See
MEXMexico Tlaxcala, Tlaxcala city0.0221181See
ARMArmenia living in Karabakh0.0220445See
CZECzech Republic Romani pop 24.40.021746See
CHNChina Shandong Province Linqu County4.30.0217139See
NORNorway ethnic Norwegians4.10.02084510See
GRCGreece pop 70.020711250See
BRABrazil Curitiba-Parana Mixed0.0205264See
IRQIraq Arabs4.00.0201149See
MEXMexico Baja California, Tijuana0.020025See
ITAItaly East Sicily4.00.020050See
ARMArmenia Lori0.0200102See
GRCGreece North0.0200500See
VENVenezuela Caracas Mestizo0.020050See
DEUGermany Essen4.00.0200174See
ROMRomania pop 20.02006936See
MARMorocco Casablanca0.0200100See
MEXMexico Nuevo Leon Rural0.0193439See
SVKSlovakia pop 20.01864234See
MEXMexico Puebla, Puebla city0.01851994See
MEXMexico Hidalgo Rural0.018581See
MEXMexico Tlaxcala Rural0.0181830See
MEXMexico Puebla Rural0.0180833See
ARMArmenia living in Lebanon0.0180368See
MEXMexico Yucatan, Merida0.0179192See
MEXMexico Zacatecas, Zacatecas city0.017984See
SWESweden pop 43.50.0176966See
ARMArmenia living in USA0.0170233See
RUSRussia Moscow0.01702650See
ARGArgentina Rosario Toba3.50.017086See
RUSRussia Tatars0.0169355See
MEXMexico Morelos Rural0.016730See
ROMRomania pop 33.30.01671469See
BIHBosnia and Herzegovina pop 23.30.0167120See
MEXMexico Mexico City Metropolitan Area Rural0.0164150See
GHAGhana Accre Asutuare Akan0.0160429See
AREUnited Arab Emirates pop 23.20.0160373See
SAUSaudi Arabia pop 20.0160383See
THAThailand Northeast0.016066See
INDIndia sub-Himalayan West Bengal Kami3.20.0158158See
RUSRussia Moscow Pop 23.20.01582000See
MKDMacedonia MBMDR - Macedonian3.00.01561283See
MEXMexico Nayarit, Tepic0.015597See
GBRUnited Kingdom South West0.0153163See
MEXMexico Mexico City West0.015233See
ALBAlbania pop 23.00.0150432See
CHNChina Shaanxi Province Han0.015010000See
CHNChina Shandong Province2.90.01507418See
CHNChina Harbin Manchu0.0150172See
ITAItaly Sardinia pop30.0150100See
TURTurkey pop 20.0150228See
POLPoland pop 33.00.01482907See
MEXMexico Mexico City North0.0146751See
MEXMexico Sonora, Ciudad Obregón0.0140143See
BGDBangladesh Dhaka Bangalee0.0140141See
SWESweden Stockholm2.70.01401347See
MEXMexico Veracruz, Xalapa0.0134187See
THAThailand Northeast pop 20.0130400See
MEXMexico Sonora Rural0.0127197See
HRVCroatia pop 32.50.0125120See
ALBAlbanian Kosovo0.0125120See
RUSRussia Samara Region0.01202500See
MKDMacedonia pop 30.0120172See
SWESweden Uppsala2.40.0120300See
RUSRussia Nenet Mixed0.012055See
MEXMexico Tamaulipas Rural0.0119125See
MEXMexico Veracruz, Veracruz city0.0116171See
MEXMexico Colima Rural0.011443See
MEXMexico Yucatan Rural0.0112132See
TURTurkey pop 50.0110142See
BFABurkina Faso Rimaibe0.011047See
SDNSudan South Nuba2.20.011046See
RUSRussia Northwest pop 22.20.0110346See
RUSRussia South Ural Russian1.90.0100207See
RUSRussia Northwest pop 32.00.0100100See
CHNChina Harbin Korean0.0100201See
TWNTaiwan Chinese immigrants from North China0.0100152See
MNGMongolia Khalkha pop 20.0100202See
RUSRussia Arkhangelsk Pomor0.010063See
MNGMongolia Khalkha0.0100200See
MNGMongolia Oold0.0100104See
MEXMexico Quintana Roo Rural0.010050See
MEXMexico Mexico City South0.009652See
ARGArgentina Chiriguano1.90.009054See
TWNTaiwan Chinese immigrants from South China0.0090172See
CHNChina Yunnan Province Naxi0.0090118See
CHNChina Jiangsu Province0.009020248See
CHNChina Guangdong Province1.70.0085403See
USAUSA OPTN Asian0.0080261See
MYSMalaysia pop 30.00801445See
CHNChina Wuhan1.70.0080121See
INDIndia North pop 30.0080587See
SRBSerbia Vojvodina1.70.0080400See
MMRMyanmar Mon1.60.007864See
RUSRussia Northwest1.50.00751011See
BIHBosnia and Herzegovina0.0074134See
SRBSerbia pop 31.50.00731992See
BOLBolivia Quechua0.007269See
KORSouth Korea pop 80.00707096See
RUSRussia South Ural Tatar1.50.0070135See
TWNTaiwan Chinese immigrants from Middle China0.0070211See
CHNChina Shanghai0.007026266See
PERPeru Lamas City Lama0.006083See
THAThailand pop 40.006016807See
MEXMexico Aguascalientes state0.005395See
BRABrazil Parana Japanese1.00.0052192See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.005094See
HRVCroatia pop 20.0050100See
LKASri Lanka Colombo Sinhalese0.0050101See
PAKPakistan Burusho0.005092See
TWNTaiwan Minnan and Hakka0.0030190See
RUSRussia Transbaikal Territory Buryats1.00.0030150See
KORSouth Korea pop 10.0020324See
TWNTaiwan Minnan pop 20.00107137See
TWNTaiwan Aborigine0.0000111See
TWNTaiwan Hakka pop 20.0000714See
JPNJapan Hyogo Osaka and Nagano0.0000195See
MNGMongolia Ulaanbaatar Khalkha0.000041See
TTOTrinidad South Asian0.000087See
MEXMexico Huasteca Region Teenek0.000055See
ARGArgentina Salta Wichi pop 20.00.000019See
RUSRussia Murmansk Saomi Mixed0.000070See
PAKPakistan Mixed Sindhi0.0000101See
MNGMongolia Tsaatan0.0000144See
VENVenezuela Colonia Tovar0.000086See
MYSMalaysia pop 20.000062See
FRAFrance Reims0.0000102See
BRABrazil Parana Oriental0.00.000033See
CHNChina North Han0.0000105See
INDIndia Kerala Hindu Pulaya0.000016See
INDIndia Kerala Syrian Christian0.000031See
INDIndia Kerala Hindu Ezhava0.000024See
INDIndia Kerala Malabar Muslim0.000034See
INDIndia Kerala Hindu Namboothiri0.000040See
BFABurkina Faso Mossi0.000053See
CMRCameroon Uldeme0.000035See
RUSRussia South Ural Bashkir0.00.0000146See
MYSMalaysia Perak Rawa0.000023See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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