Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 172 time(s) and present in 107 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
STPSao Tome Island Angolar0.063032See
USAUSA African American Bethesda7.90.0500187See
BFABurkina Faso Mossi0.038053See
CMRCameroon Beti0.0370174See
ZMBZambia Lusaka0.035044See
USAUSA NMDP Caribean Black0.033533328See
USAUSA African American0.0320252See
USAUSA African American pop 30.0310564See
TUNTunisia Ghannouch0.030082See
STPSao Tome Island Forro0.030066See
KENKenya Luo0.0300265See
USAUSA NMDP African0.029528557See
ZWEZimbabwe Harare Shona0.0290230See
UGAUganda Kampala pop 20.0290175See
TZATanzania Maasai4.80.0269336See
CMRCameroon Bamileke0.026077See
USAUSA NMDP African American pop 20.0253416581See
CRICosta Rica African -Caribbean (G)5.00.0250102See
KENKenya, Nyanza Province, Luo tribe5.00.0250100See
USAUSA African American pop 40.02412411See
JORJordan Amman0.0240146See
BRABrazil Rio de Janeiro Black0.022168See
CMRCameroon Yaounde0.022092See
BRABrazil Rio de Janeiro Parda0.0206170See
BRABrazil Barra Mansa Rio State Black0.020573See
BFABurkina Faso Fulani0.020049See
USAUSA African American pop 20.0200149See
CRICosta Rica Guanacaste Mestizo (G)3.60.0180110See
VENVenezuela Colonia Tovar0.017486See
BRABrazil Belo Horizonte Caucasian2.10.016095See
ISRIsrael Druze0.01555914See
SDNSudan Central Shaigiya Mixed2.70.013536See
KENKenya Nandi0.0130240See
UGAUganda Kampala0.0120161See
SDNSudan South Nuba2.20.011046See
TUNTunisia pop 30.0110104See
BFABurkina Faso Rimaibe0.011047See
CMRCameroon Bakola Pygmy2.00.010050See
BRABrazil Mixed0.0100108See
COLColombia North Wiwa El Encanto0.009652See
GHAGhana Ga-Adangbe1.50.0076131See
ZAFSouth African Black1.40.0070142See
ZAFSouth Africa Worcester1.00.0060159See
USAUSA NMDP Caribean Indian0.006014339See
BRABrazil Rio de Janeiro Caucasian0.0058521See
TUNTunisia Gabes0.005295See
USAUSA Spain Ancestry0.0050279See
AREUnited Arab Emirates Pop 10.0050570See
MEXMexico Guadalajara Mestizo pop 20.0050103See
USAUSA Hispanic0.0040234See
USAUSA Mexican American Mestizo0.0040553See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0040146See
CRICosta Rica Amerindians (G)0.80.0040125See
USAUSA NMDP Caribean Hispanic0.0040115374See
MEXMexico Mexico City Mestizo population0.0035143See
NICNicaragua Managua0.60.0030339See
USAUSA San Diego0.60.0030496See
SDNSudan Mixed0.50.0030200See
USAUSA Hispanic pop 20.00281999See
USAUSA NMDP Hispanic South or Central American0.0026146714See
ESPSpain, Canary Islands, Gran canaria island0.50.0023215See
ISRIsrael Arab pop 20.002212301See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
USAUSA NMDP American Indian South or Central America0.00205926See
MYSMalaysia Peninsular Indian0.40.0018271See
SAUSaudi Arabia pop 6 (G)0.001728927See
DEUGermany DKMS - Portugal minority0.00171176See
BRABrazil Barra Mansa Rio State Caucasian0.0012405See
USAUSA NMDP Mexican or Chicano0.0011261235See
ITAItaly pop 50.0010975See
USAUSA Eastern European0.0010558See
USAUSA NMDP North American Amerindian0.000935791See
COLColombia Bogotá Cord Blood0.10.00071463See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00051028See
DEUGermany DKMS - United Kingdom minority0.00051043See
ISRIsrael Georgia Jews0.00034471See
DEUGermany DKMS - Netherlands minority0.00041374See
DEUGermany DKMS - Turkey minority0.00034856See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00034335See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000270890See
USAUSA NMDP Hawaiian or other Pacific Islander0.000211499See
ISRIsrael Tunisia Jews0.00029070See
USAUSA NMDP European Caucasian0.00011242890See
DEUGermany pop 60.00018862See
DEUGermany DKMS - German donors0.00013456066See
USAUSA NMDP Southeast Asian0.000127978See
USAUSA NMDP Japanese0.000124582See
USAUSA NMDP Vietnamese0.000143540See
ISRIsrael USA Jews0.00016058See
USAUSA NMDP Filipino0.000050614See
ISRIsrael Iraq Jews0.000013270See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP South Asian Indian0.0000185391See
ISRIsrael Libya Jews0.00003739See
ISRIsrael Ashkenazi Jews pop 30.00004625See
ISRIsrael Morocco Jews0.000036718See
ISRIsrael Iran Jews0.00008153See
ISRIsrael YemenJews0.000015542See
USAUSA NMDP Korean0.000077584See
ISRIsrael USSR Jews0.000045681See
ITAItaly Sardinia pop30.0000100See
MLIMali Bandiagara0.0000138See
MEXMexico Mestizo0.00.000041See
KORSouth Korea pop 30.0000485See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
HKGHong Kong Chinese0.00.0000569See
INDIndia Mumbai Maratha0.000091See
NIRIreland Northern0.00.00001000See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
FRAFrance Corsica Island0.0000100See
DEUGermany pop 80.000039689See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina North Han0.0000105See
ESPSpain Majorca and Minorca0.000090See
ESPSpain Gipuzkoa Basque0.0000100See
ESPSpain Catalonia Girona0.000088See
ZAFSouth Africa Caucasians0.0000102See
USAUSA North American Native0.0000187See
USAUSA Asian0.0000358See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA Caucasian pop 20.0000265See
USAUSA Caucasian pop 40.00001070See
USAUSA Asian pop 20.00001772See
USAUSA Caucasian pop 30.000088See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
SCOScotland Orkney0.00.000099See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
PHLPhilippines Ivatan0.00.000050See
POLPoland DKMS0.000020653See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
NLDNetherlands Leiden0.00001305See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
VENVenezuela Caracas Mestizo0.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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