Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 
   

A*66:01

 
Allele reported 225 time(s) and present in 184 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
CMRCameroon Sawa0.077013See
KENKenya Luo0.0680265See
UGAUganda Kampala pop 20.0660175See
CMRCameroon Yaounde0.060092See
ESPSpain Andalusia Gipsy0.058099See
CMRCameroon Bakola Pygmy10.00.051350See
CMRCameroon Baka Pygmy0.050010See
KENKenya, Nyanza Province, Luo tribe10.00.0500100See
KENKenya Nandi0.0500240See
CMRCameroon Beti0.0460174See
CMRCameroon Bamileke0.045077See
TUNTunisia Ghannouch0.043082See
ZAFSouth Africa Worcester8.00.0410159See
INDIndia West Bhil0.040050See
ZWEZimbabwe Harare Shona0.0380230See
ISRIsrael Ethiopia Jews0.03245928See
STPSao Tome Island Angolar0.031032See
UGAUganda Kampala0.0280161See
SAUSaudi Arabia pop 53.80.0253158See
INDIndia Mumbai Maratha0.025091See
CPVCape Verde Northwestern Islands0.024062See
CZECzech Republic0.0240106See
CUBCuba Caucasian4.30.021070See
MARMorocco Nador Metalsa pop 20.021073See
CHESwitzerland Aargau-Solothurn0.02091838See
MTQMartinique0.0200100See
PRTPortugal Center0.020050See
INDIndia West Coast Parsi0.020050See
ZAFSouth Africa Natal Zulu4.00.0200100See
USAUSA African American0.0200252See
ISRIsrael Tunisia Jews0.01919070See
ISRIsrael Argentina Jews0.01784307See
ISRIsrael Libya Jews0.01773739See
KENKenya0.0170144See
TUNTunisia pop 30.0170104See
ISRIsrael USA Jews0.01696058See
ISRIsrael Druze0.01665914See
GNBGuinea Bissau Fula0.016031See
USAUSA NMDP African0.015628557See
ISRIsrael Poland Jews0.015213871See
BRABrazil Pernambuco Mixed0.0150101See
GNBGuinea Bissau0.015065See
USAUSA African American Bethesda3.00.0150187See
ISRIsrael Ashkenazi Jews pop 30.01494625See
USAUSA African American pop 40.01482411See
CHESwitzerland Geneva pop 20.01431267See
USAUSA NMDP African American pop 20.0141416581See
GEOGeorgia Tibilisi0.0140109See
MARMorocco Atlantic Coast Chaouya0.014098See
MARMorocco Settat Chaouya2.80.014098See
CHESwitzerland St Gallen0.01352113See
PRTPortugal Azores Terceira Island2.60.0132130See
USAUSA NMDP Caribean Black0.013133328See
USAUSA African American pop 30.0130564See
USAUSA Italy Ancestry0.0130273See
MEXMexico Mexico City Mestizo pop 20.0128234See
ISRIsrael YemenJews0.012615542See
CUBCuba Mulatto2.40.012042See
SAUSaudi Arabia Guraiat and Hail2.30.0120213See
PRTAzores Terceira Island0.0120130See
ZMBZambia Lusaka0.012044See
ISRIsrael USSR Jews0.011545681See
ITAItaly Bergamo2.00.0110101See
PRTMadeira0.0110185See
PAKPakistan Karachi Parsi0.011091See
ISRIsrael Kavkazi Jews0.01092840See
ISRIsrael Bukhara Jews0.01082317See
ISRIsrael Arab pop 20.010712301See
PRTPortugal South0.010049See
BRABrazil Mixed0.0100108See
ASMAmerican Samoa0.010051See
ZAFSouth African Mixed ancestry2.00.010050See
USAUSA NMDP Caribean Indian0.010014339See
CHESwitzerland Luzern0.00981553See
USAUSA NMDP Caribean Hispanic0.0097115374See
AREUnited Arab Emirates Abu Dhabi0.009652See
LBYLibya Cyrenaica0.0090118See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0090146See
USAUSA San Antonio Caucasian0.0090222See
CHESwitzerland Zurich0.00854875See
CZECzech Republic NMDR0.00825099See
CPVCape Verde Southeastern Islands0.008062See
CHESwitzerland Lugano0.00801169See
ITAItaly pop 50.0080975See
IRLIreland South1.60.0080250See
OMNOman1.70.0080118See
ZAFSouth Africa Black0.0080200See
USAUSA Caucasian pop 20.0080265See
SDNSudan Mixed1.50.0080200See
STPSao Tome Island Forro0.008066See
ECUEcuador Amerindians0.007963See
ISRIsrael Morocco Jews0.007936718See
CHESwitzerland Basel0.00791888See
GHAGhana Ga-Adangbe1.50.0076131See
NICNicaragua Managua1.50.0075339See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,1.40.00734335See
DEUGermany DKMS - Greece minority0.00711894See
POLPoland DKMS0.007120653See
USAUSA San Francisco Caucasian0.0070220See
USAUSA NMDP Hispanic South or Central American0.0064146714See
DEUGermany DKMS - Italy minority0.00651159See
DEUGermany DKMS - Turkey minority0.00644856See
GRCGreece pop 60.0062242See
USAUSA NMDP Middle Eastern or North Coast of Africa0.006170890See
USAUSA Eastern European0.0060558See
USAUSA Caucasian pop 30.006088See
DEUGermany DKMS - Austria minority0.00601698See
PAKPakistan Brahui0.0060104See
MEXMexico Veracruz Xalapa1.20.006084See
IRNIran Baloch0.0060100See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00581028See
DEUGermany DKMS - Spain minority0.00581107See
VENVenezuela Colonia Tovar0.005886See
DEUGermany DKMS - Romania minority0.00571234See
ISRIsrael Georgia Jews0.00564471See
USAUSA Hispanic pop 20.00551999See
TUNTunisia Gabes0.005295See
DEUGermany DKMS - Portugal minority0.00511176See
DEUGermany DKMS - France minority0.00501406See
ENGEngland North West1.00.0050298See
BRABrazil Belo Horizonte Caucasian1.10.005095See
ARMArmenia combined Regions0.0050100See
BELBelgium1.00.005099See
CHLChile Santiago Mixed1.00.005070See
INDIndia Delhi pop 21.10.005090See
MEXMexico Guadalajara Mestizo pop 20.0050103See
POLPoland0.0050200See
TUNTunisia1.00.0050100See
USAUSA Mexican American Mestizo0.0050553See
USAUSA NMDP Mexican or Chicano0.0049261235See
DEUGermany DKMS - United Kingdom minority0.00481043See
DEUGermany pop 60.00448862See
CHESwitzerland Bern0.00423545See
COLColombia Bogotá Cord Blood0.80.00411463See
CHESwitzerland Lausanne0.0041993See
USAUSA NMDP European Caucasian0.00411242890See
RUSRussia Karelia0.00411075See
USAUSA Hispanic0.0040234See
USAUSA NMDP American Indian South or Central America0.00405926See
USAUSA Philadelphia Caucasian0.70.0040141See
USAUSA Caucasian0.80.004061655See
FRAFrance Southeast0.80.0040130See
MNGMongolia Buryat0.0040141See
HRVCroatia pop 40.00384000See
DEUGermany DKMS - Croatia minority0.00372057See
USAUSA Caucasian pop 40.00371070See
DEUGermany DKMS - Netherlands minority0.00361374See
FRAFrance French Bone Marrow Donor Registry0.003442623See
CHESwitzerland Sion0.0032832See
USAUSA NMDP North American Amerindian0.003235791See
USAUSA NMDP Alaska Native or Aleut0.00301376See
USAUSA San Diego0.60.0030496See
RUSRussia Tuva pop 20.0030169See
HRVCroatia0.0030150See
MEXMexico Mexico City Tlalpan0.60.0030330See
NLDNetherlands Leiden0.00301305See
MKDMacedonia pop 40.0020216See
AUTAustria0.50.0020200See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
USAUSA Spain Ancestry0.0020279See
WALWales0.30.00201798See
CHNChina Jiangsu Province Han0.0018334See
ISRIsrael Iraq Jews0.001413270See
HKGHong Kong Chinese0.20.0010569See
NIRIreland Northern0.20.00101000See
USAUSA Asian0.0010358See
ROMRomania0.30.0010348See
USAUSA NMDP Hawaiian or other Pacific Islander0.000911499See
USAUSA NMDP Filipino0.000950614See
USAUSA NMDP Southeast Asian0.000627978See
HKGHong Kong Chinese cord blood registry0.00053892See
CHESwitzerland Graubunden0.0004759See
USAUSA NMDP South Asian Indian0.0003185391See
HKGHong Kong Chinese BMDR0.00037595See
DEUGermany DKMS - China minority0.00041282See
CHNChina Jiangsu Han0.00033238See
USAUSA NMDP Chinese0.000299672See
USAUSA Asian pop 20.00031772See
ISRIsrael Iran Jews0.00028153See
JPNJapan pop 160.000118604See
USAUSA NMDP Japanese0.000124582See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP Korean0.000077584See
USAUSA Alaska Yupik0.0000252See
USAUSA North American Native0.0000187See
USAUSA African American pop 20.0000149See
USAUSA Caucasian Bethesda0.00.0000307See
SGPSingapore Chinese0.00.0000149See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
VENVenezuela Caracas Mestizo0.000050See
ZAFSouth Africa Caucasians0.0000102See
GNBGuinea Bissau Papel0.000025See
INDIndia Khandesh Region Pawra0.000050See
PAKPakistan Baloch0.000066See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PHLPhilippines Ivatan0.00.000050See
PRTPortugal North0.000046See
MLIMali Bandiagara0.0000138See
MEXMexico Mestizo0.00.000041See
KORSouth Korea pop 30.0000485See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
BGRBulgaria0.000055See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
GNBGuinea Bissau Balanta0.000048See
GNBGuinea Bissau Bijago0.000023See
FRAFrance Rennes pop 30.0000200See

Frequency data at lower resolution for this allele can be found in links below


Allele  Number of Populations 

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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