Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 44 time(s) and present in 40 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CANCanada Chipewyan NA-DHS_2 (G)28.00.140025See
USAUSA Arizona Gila River Pima0.08643000See
CANCanada Cree NA-DHS_3 (G)16.70.083318See
MEXMexico Chihuahua Tarahumara0.068044See
CANCanada Ojibwa NA-DHS_4 (G)13.30.066716See
RUSRussia Nizhny Novgorod, Russians8.30.04271510See
RUSRussia Bashkortostan, Tatars8.30.0417192See
POLPoland BMR7.70.039023595See
USAUSA Eastern European0.0390558See
INDIndia North pop 20.038072See
ENGEngland Blood Donors of Mixed Ethnicity7.30.0376519See
RUSRussia Bashkortostan, Bashkirs7.50.0375120See
RUSRussia Belgorod region6.50.0359153See
USAUSA San Francisco Caucasian0.0340220See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.30.031316See
ZAFSouth African Mixed ancestry6.00.030050See
COLColombia Arhuaco NA-DHS_16 (G)5.90.029417See
MEXMexico Guadalajara Mestizo pop 20.0290103See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
USAUSA Italy Ancestry0.0260273See
BRABrazil Rio de Janeiro Black0.022468See
USAUSA Mexican American Mestizo0.0220553See
RUSRussian Federation Vologda Region4.20.0210119See
MARMorocco Nador Metalsa pop 20.021073See
BRABrazil Barra Mansa Rio State Caucasian0.0198405See
GRCGreece Athens3.20.01591888See
BRABrazil Rio de Janeiro Caucasian0.0125521See
BRABrazil Rio de Janeiro Parda0.0118170See
NICNicaragua Mestizo (G)2.00.0100155See
ESPSpain, Canary Islands, Gran canaria island1.40.0069215See
CRICosta Rica Central Valley Mestizo (G)1.00.0050221See
IRNIran Baloch0.0050100See
SAUSaudi Arabia pop 6 (G)0.004828927See
CHNChina Zhejiang Han0.00461734See
FRAFrance Southeast0.80.0040130See
USAUSA Spain Ancestry0.0040279See
INDIndia Kerala Malayalam speaking0.60.0030356See
INDIndia Andhra Pradesh Telugu Speaking0.50.0027186See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.30.00135266See
MARMorocco Settat Chaouya0.00.000098See
KORSouth Korea pop 30.0000485See
CHNChina North Han0.0000105See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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