Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 234 time(s) and present in 197 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SWESweden Northern Sami0.2000154See
USAUSA Alaska Yupik0.1150252See
SWESweden Southern Sami0.1050130See
USAUSA NMDP Alaska Native or Aleut0.08901376See
USAUSA North American Native0.0860187See
USAUSA Arizona Pima0.0790100See
USAUSA South Dakota Lakota Sioux0.0740302See
USAUSA Arizona Gila River Amerindian0.0620492See
USAUSA NMDP North American Amerindian0.054535791See
RUSRussia Karelia0.04821075See
POLPoland DKMS0.046820653See
AUSAustralia New South Wales Caucasian0.0450134See
USAUSA Caucasian Bethesda8.60.0430307See
IRLIreland South8.40.0420250See
ENGEngland North West8.10.0420298See
CHESwitzerland St Gallen0.04182113See
ZAFSouth Africa Caucasians0.0410102See
USAUSA European American pop 20.04101245See
INDIndia Tamil Nadu Nadar0.041061See
DEUGermany DKMS - Croatia minority0.04082057See
INDIndia Khandesh Region Pawra0.040050See
USAUSA NMDP American Indian South or Central America0.04005926See
HRVCroatia pop 40.03984000See
USAUSA Caucasian pop 40.03911070See
USAUSA NMDP European Caucasian0.03731242890See
USAUSA New Mexico Canoncito Navajo0.037042See
DEUGermany pop 60.03718862See
DEUGermany DKMS - German donors0.03663456066See
DEUGermany DKMS - Netherlands minority0.03571374See
CHESwitzerland Lausanne0.0356993See
DEUGermany DKMS - France minority0.03521406See
CZECzech Republic NMDR0.03465099See
DEUGermany DKMS - United Kingdom minority0.03451043See
DEUGermany pop 80.034039689See
DEUGermany DKMS - Bosnia and Herzegovina minority0.03411028See
SRBSerbia pop 26.90.0340102See
USAUSA San Francisco Caucasian0.0340220See
CHESwitzerland Graubunden0.0340759See
CHESwitzerland Bern0.03343545See
PRTPortugal North0.033046See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,6.50.03294335See
CHESwitzerland Sion0.0321832See
NLDNetherlands UMCU6.30.031264See
DEUGermany DKMS - Austria minority0.03091698See
CHLChile Mapuche0.030866See
DEUGermany DKMS - Romania minority0.03041234See
NLDNetherlands Leiden0.02901305See
NIRIreland Northern5.50.02901000See
RUSRussia Bering Island Aleuts0.0288104See
FRAFrance French Bone Marrow Donor Registry0.028742623See
CZECzech Republic0.0280106See
PRTAzores Terceira Island0.0270130See
PRTAzores Oriental Islands0.026043See
USAUSA San Diego4.80.0260496See
USAUSA Hispanic0.0260234See
CHESwitzerland Luzern0.02581553See
KORSouth Korea pop 30.0250485See
USAUSA NMDP Korean0.024977584See
KORSouth Korea pop 100.02484128See
GRCGreece pop 84.80.024183See
CPVCape Verde Northwestern Islands0.024062See
NZLNew Zealand Polynesians with Full Ancestry4.80.024021See
FRAFrance Southeast4.60.0230130See
USAUSA Caucasian pop 20.0230265See
DEUGermany DKMS - Spain minority0.02271107See
USAUSA NMDP Mexican or Chicano0.0222261235See
ZAFSouth Africa Worcester4.00.0220159See
DEUGermany DKMS - Portugal minority0.02131176See
PRTPortugal South0.020049See
ESPSpain Andalusia Romani0.020099See
NZLNew Zealand Polynesians with Admixed History3.70.019027See
ITAItaly North Pavia0.019081See
CHESwitzerland Basel0.01891888See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0180146See
PRTAzores Central Islands0.018059See
DEUGermany DKMS - Greece minority0.01801894See
USAUSA NMDP Caribean Hispanic0.0172115374See
INDIndia East UCBB3.40.01712403See
GEOGeorgia Tibilisi Kurd0.017031See
CHESwitzerland Zurich0.01694875See
USAUSA Hispanic pop 20.01681999See
CHESwitzerland Aargau-Solothurn0.01611838See
USAUSA NMDP Hispanic South or Central American0.0160146714See
USAUSA NMDP Caribean Indian0.016014339See
CPVCape Verde Southeastern Islands0.016062See
BRABrazil Belo Horizonte Caucasian3.20.016095See
ITAItaly pop 50.0160975See
MEXMexico Oaxaca Jamiltepec Mixtec0.016096See
MEXMexico Mixtec0.016097See
DEUGermany DKMS - Italy minority0.01601159See
INDIndia Central UCBB3.00.01524204See
CHLChile Santiago Mixed3.00.015170See
USAUSA San Antonio Caucasian0.0151222See
CHNChina Yunnan Province Han0.0150101See
CHNChina Sichuan HIV negative0.015034See
INDIndia New Delhi0.015071See
MEXMexico Sonora Seri0.015034See
USAUSA NMDP Middle Eastern or North Coast of Africa0.014870890See
DEUGermany DKMS - Turkey minority0.01444856See
GRCGreece pop 60.0142242See
CUBCuba Caucasian2.90.014070See
USAUSA Asian0.0140358See
USAUSA South Texas Hispanic0.0130194See
UGAUganda Kampala0.0120161See
USAUSA African American0.0120252See
CUBCuba Mixed Race2.40.012042See
CHNChina Jiangsu Han0.01203238See
MEXMexico Mestizo2.40.012041See
INDIndia North UCBB2.40.01195849See
ISRIsrael Morocco Jews0.011536718See
INDIndia West UCBB2.30.01135829See
INDIndia Delhi pop 22.20.011090See
COLColombia Bogotá Cord Blood2.10.01061463See
PRTPortugal Center0.010050See
ZAFSouth Africa Natal Tamil0.010051See
MEXMexico Oaxaca Mixtec0.0100103See
NICNicaragua Managua1.80.0090339See
USAUSA African American pop 30.0090564See
PRTPortugal Azores Terceira Island1.80.0088130See
USAUSA NMDP African American pop 20.0084416581See
USAUSA Asian pop 20.00851772See
USAUSA NMDP South Asian Indian0.0083185391See
RUSRussia Tuva pop 20.0080169See
STPSao Tome Island Forro0.008066See
CHNChina Beijing0.008067See
SDNSudan Mixed1.50.0080200See
USAUSA NMDP Hawaiian or other Pacific Islander0.007611499See
DEUGermany DKMS - China minority0.00741282See
CHESwitzerland Lugano0.00721169See
USAUSA NMDP Southeast Asian0.007127978See
USAUSA Philadelphia Caucasian1.50.0070141See
INDIndia Northeast UCBB1.40.0068296See
USAUSA NMDP Caribean Black0.006733328See
USAUSA African American pop 40.00662411See
MEXMexico Mexico City Mestizo pop 20.0064234See
ISRIsrael USSR Jews0.006445681See
CHNChina Marrow Donor Registry0.0060600See
CMRCameroon Bamileke0.006077See
USAUSA African American pop 80.0060605See
USAUSA NMDP African0.005928557See
INDIndia South UCBB1.20.005811446See
ISRIsrael Kavkazi Jews0.00512840See
SAUSaudi Arabia Guraiat and Hail1.00.0050213See
PERPeru Titikaka Lake Uros0.0050105See
PERPeru Titikaka Lake Uro0.0050105See
NZLNew Zealand Maori with Admixed History1.00.0050105See
GEOGeorgia Tibilisi0.0050109See
ARMArmenia combined Regions0.0050100See
AUSAustralia Cape York Peninsula Aborigine0.0050103See
CHNChina Southwest Dai0.0050124See
CHNChina Guangzhou0.0050102See
CHNChina Qinghai Province Hui0.0050110See
CHNChina Beijing Shijiazhuang Tianjian Han0.0050618See
USAUSA African American Bethesda1.10.0050187See
LKASri Lanka Colombo1.00.0050714See
CHNChina Hubei Han0.80.00423732See
AREUnited Arab Emirates Pop 10.0040570See
INDIndia Tamil Nadu0.00402492See
CHNChina Jiangsu Province Han0.0036334See
ISRIsrael Arab pop 20.003612301See
USAUSA NMDP Chinese0.003599672See
CHESwitzerland Geneva pop 20.00331267See
USAUSA NMDP Filipino0.003250614See
TWNTaiwan Han Chinese0.0030504See
CHNChina Tibet Region Tibetan0.0030158See
CMRCameroon Beti0.0030174See
ISRIsrael Ashkenazi Jews pop 30.00244625See
USAUSA NMDP Vietnamese0.002443540See
USAUSA NMDP Japanese0.002324582See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0021233See
KENKenya Luo0.0020265See
ISRIsrael Poland Jews0.001913871See
MYSMalaysia Peninsular Indian0.40.0018271See
ISRIsrael USA Jews0.00176058See
TWNTaiwan Tzu Chi Morrow Donor Registry0.001546682See
ISRIsrael Georgia Jews0.00154471See
ISRIsrael YemenJews0.001315542See
JPNJapan pop 30.00101018See
JPNJapan Central0.0010371See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
ISRIsrael Iraq Jews0.000613270See
JPNJapan pop 160.000618604See
ISRIsrael Argentina Jews0.00054307See
ISRIsrael Iran Jews0.00058153See
ISRIsrael Tunisia Jews0.00029070See
ISRIsrael Ethiopia Jews0.00025928See
ISRIsrael Druze0.00025914See
ISRIsrael Libya Jews0.00013739See
KENKenya Nandi0.0000240See
MLIMali Bandiagara0.0000138See
MEXMexico Oaxaca Zapotec0.000090See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
STPSao Tome Island Angolar0.000032See
PHLPhilippines Ivatan0.00.000050See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CMRCameroon Bakola Pygmy0.00.000050See
AUSAustralia Yuendumu Aborigine0.0000191See
CHNChina Inner Mongolia Region0.0000102See
CHNChina North Han0.0000105See
INDIndia Mumbai Maratha0.000091See
INDIndia West Coast Parsi0.000050See
GNBGuinea Bissau0.000065See
HKGHong Kong Chinese0.00.0000569See
INDIndia West Bhil0.000050See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
ZMBZambia Lusaka0.000044See

See also higher resolution data of this allele

Allele  Number of Populations 
 B*27:05:02 44 
 B*27:05:03 10 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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