Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 30 time(s) and present in 30 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Hidalgo Mezquital Valley/ Otomi12.50.069472See
CRICosta Rica Central Valley Mestizo (G)7.30.0390221See
RUSRussia Bashkortostan, Tatars7.30.0365192See
USAUSA San Francisco Caucasian0.0300220See
RUSRussian Federation Vologda Region5.90.0294119See
NICNicaragua Mestizo (G)5.20.0290155See
RUSRussia Nizhny Novgorod, Russians5.70.02881510See
RUSRussia Belgorod region4.60.0229153See
POLPoland BMR4.40.022323595See
BRABrazil Rio de Janeiro Black0.022168See
BRABrazil Rio de Janeiro Caucasian0.0211521See
BRABrazil Barra Mansa Rio State Caucasian0.0210405See
BRABrazil Barra Mansa Rio State Black0.020573See
INDIndia Kerala Malayalam speaking3.40.0170356See
LBYLibya Cyrenaica0.0170118See
RUSRussia Bashkortostan, Bashkirs3.30.0167120See
INDIndia Andhra Pradesh Telugu Speaking3.20.0161186See
CHNChina Zhejiang Han0.01561734See
ZAFSouth African Black2.80.0141142See
CHNChina Han Guandong Province0.0140208See
ESPSpain, Canary Islands, Gran canaria island2.80.0140215See
BRABrazil Rio de Janeiro Parda0.0118170See
INDIndia Karnataka Kannada Speaking2.30.0110174See
TWNTaiwan Minnan and Hakka0.0110190See
HKGHong Kong Chinese HKBMDR HLA 11 loci1.80.00905266See
CRICosta Rica Guanacaste Mestizo (G)1.80.0090110See
CHNChina Inner Mongolia Autonomous Region Northeast1.80.0090496See
CRICosta Rica Amerindians (G)1.60.0080125See
SAUSaudi Arabia pop 50.60.0032158See
USAUSA Arizona Gila River Pima0.00263000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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