Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 246 time(s) and present in 221 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CMRCameroon Baka Pygmy0.250010See
CMRCameroon Sawa0.231013See
LKASri Lanka Colombo33.90.1880714See
INDIndia West Bhil0.180050See
MYSMalaysia Patani36.00.180025See
PAKPakistan Burusho0.179092See
MYSMalaysia Jelebu Temuan0.167025See
KORSouth Korea pop 30.1630485See
IDNIndonesia Java Western29.70.1620236See
KORSouth Korea pop 100.16094128See
GNBGuinea Bissau Papel0.160025See
USAUSA NMDP Korean0.152977584See
SGPSingapore SGVP Chinese CHS0.152096See
MYSMalaysia Kelantan28.60.143028See
INDIndia West Coast Parsi0.140050See
SGPSingapore SGVP. Indian INS0.137086See
SGPSingapore Thai0.1330100See
INDIndia Mumbai Maratha0.130091See
JPNJapan pop 50.1280117See
PAKPakistan Baloch0.127066See
MYSMalaysia Champa24.10.121029See
TWNTaiwan Tzu Chi Morrow Donor Registry0.120546682See
MYSMalaysia Sarawak Bau Bidayuh0.120025See
USAUSA NMDP Vietnamese0.118843540See
TWNTaiwan Han Chinese0.1180504See
USAUSA Asian0.1170358See
VNMVietnam Hanoi Kinh pop 20.1150170See
CHNChina South Han0.1150284See
TWNTaiwan pop 20.1140364See
CHNChina Jiangsu Han0.11183238See
TWNTaiwan pop 30.1090212See
SGPSingapore Riau Malay0.1090132See
HKGHong Kong Chinese BMDR0.10477595See
CHNChina Jiangsu Province Han0.1045334See
TWNTaiwan Tzu Chi Cord Blood Bank0.1040710See
USAUSA NMDP Chinese0.101199672See
SGPSingapore Chinese18.80.1010149See
CHNChina Southwest Dai0.1010124See
HKGHong Kong Chinese cord blood registry0.10103892See
HKGHong Kong Chinese18.90.1000569See
USAUSA NMDP South Asian Indian0.0992185391See
JPNJapan Central0.0970371See
USAUSA NMDP Southeast Asian0.094827978See
USAUSA Asian pop 20.09431772See
MLIMali Bandiagara0.0940138See
CHNChina Han HIV negative0.094072See
CHNChina Henan HIV negative0.094016See
SGPSingapore Chinese Han0.093094See
SGPSingapore Javaneses0.090051See
INDIndia North pop 20.087072See
INDIndia Tamil Nadu0.08672492See
GNBGuinea Bissau0.085065See
CHNChina Yunnan Province Han0.0840101See
GNBGuinea Bissau Balanta0.083048See
TWNTaiwan Minnan pop 116.70.0830102See
TWNTaiwan Hakka16.40.082055See
CHNChina Marrow Donor Registry0.0820600See
SENSenegal Niokholo Mandenka0.0810165See
PAKPakistan Brahui0.0800104See
MYSMalaysia Perak Grik Jehai0.080025See
DEUGermany DKMS - China minority0.07641282See
PAKPakistan Mixed Sindhi0.0760101See
JPNJapan pop 160.075118604See
CHNChina Hubei Han14.80.07423732See
PAKPakistan Mixed Pathan0.0710100See
RUSRussia Tuva pop 20.0710169See
SGPSingapore SGVP Malay MAS0.071089See
ZAFSouth Africa Natal Tamil0.070051See
PAKPakistan Karachi Parsi0.067091See
JPNJapan pop 30.06701018See
INDIndia Tamil Nadu Nadar0.066061See
GNBGuinea Bissau Bijago0.065023See
USAUSA NMDP Japanese0.064824582See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0640146See
INDIndia Andhra Pradesh Golla0.0630111See
CHNChina Beijing Shijiazhuang Tianjian Han0.0620618See
INDIndia New Delhi0.061071See
CUBCuba Mixed Race11.90.060042See
CHNChina Sichuan HIV negative0.059034See
USAUSA African American Bethesda11.90.0590187See
PAKPakistan Kalash0.058069See
USAUSA NMDP Caribean Black0.056733328See
IRNIran Baloch0.0560100See
CHNChina Guangzhou0.0540102See
USAUSA NMDP African0.052328557See
USAUSA NMDP African American pop 20.0518416581See
USAUSA NMDP Filipino0.051150614See
TWNTaiwan Thao10.00.050030See
TWNTaiwan Siraya9.80.049051See
AREUnited Arab Emirates Abu Dhabi0.048152See
GNBGuinea Bissau Fula0.048031See
STPSao Tome Island Angolar0.047032See
STPSao Tome Island Forro0.045066See
CHNChina Shanxi HIV negative0.045022See
CMRCameroon Bamileke0.045077See
USAUSA African American pop 40.04452411See
CHNChina Guangxi Region Maonan0.0420108See
MYSMalaysia Peninsular Malay7.80.0415951See
CHNChina Guangdong Province Meizhou Han0.0400100See
CPVCape Verde Southeastern Islands0.040062See
USAUSA African American0.0400252See
USAUSA African American pop 20.0400149See
MYSMalaysia Mandailing7.40.037027See
TWNTaiwan Pazeh7.30.036055See
CHNChina Yunnan Hani0.0330150See
UGAUganda Kampala0.0310161See
CHNChina Beijing0.030067See
BRABrazil Mixed0.0300108See
INDIndia Khandesh Region Pawra0.030050See
USAUSA San Diego5.50.0290496See
USAUSA NMDP Caribean Indian0.029014339See
MYSMalaysia Peninsular Chinese4.10.0284194See
CMRCameroon Yaounde0.028092See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0279233See
CHNChina Uyghur HIV negative0.026019See
SDNSudan Mixed5.00.0250200See
ZWEZimbabwe Harare Shona0.0240230See
CPVCape Verde Northwestern Islands0.024062See
USAUSA NMDP Hawaiian or other Pacific Islander0.023811499See
CMRCameroon Beti0.0230174See
USAUSA Caucasian Bethesda3.60.0220307See
USAUSA Hawaii Okinawa0.0190106See
TZATanzania Maasai3.60.0179336See
USAUSA Caucasian pop 30.017088See
USAUSA South Texas Hispanic0.0170194See
MYSMalaysia Peninsular Indian3.30.0166271See
BRABrazil Belo Horizonte Caucasian3.20.016095See
USAUSA NMDP Caribean Hispanic0.0149115374See
DEUGermany DKMS - Turkey minority0.01424856See
MARMorocco Atlantic Coast Chaouya0.014098See
MARMorocco Settat Chaouya2.80.014098See
UGAUganda Kampala pop 20.0140175See
SAUSaudi Arabia Guraiat and Hail2.80.0140213See
USAUSA Hispanic pop 20.01311999See
GRCGreece pop 60.0124242See
GRCGreece pop 82.40.012183See
MEXMexico Mestizo2.40.012041See
COLColombia Bogotá Cord Blood2.30.01131463See
PRTPortugal North0.011046See
USAUSA Hispanic0.0110234See
USAUSA NMDP Middle Eastern or North Coast of Africa0.010970890See
GEOGeorgia Tibilisi0.0100109See
ARMArmenia combined Regions0.0100100See
ISRIsrael Arab Druze0.0100101See
COLColombia North Wiwa El Encanto0.009652See
CHNChina Yunnan Bulang0.0090116See
KENKenya Luo0.0090265See
PRTAzores Central Islands0.009059See
RUSRussia Karelia0.00881075See
USAUSA NMDP Hispanic South or Central American0.0082146714See
USAUSA NMDP American Indian South or Central America0.00805926See
ECUEcuador Amerindians0.007963See
NLDNetherlands UMCU1.60.007864See
DEUGermany DKMS - Greece minority0.00771894See
NICNicaragua Managua1.50.0075339See
MEXMexico Mexico City Mestizo population0.0070143See
DEUGermany DKMS - Italy minority0.00691159See
DEUGermany DKMS - Romania minority0.00691234See
DEUGermany DKMS - Portugal minority0.00681176See
USAUSA Caucasian pop 40.00651070See
DEUGermany DKMS - Croatia minority0.00632057See
DEUGermany DKMS - France minority0.00611406See
ITAItaly pop 50.0060975See
IRLIreland South1.20.0060250See
USAUSA Caucasian pop 20.0060265See
ZAFSouth Africa Worcester1.00.0060159See
DEUGermany pop 80.005339689See
MKDMacedonia pop 40.0050216See
KENKenya, Nyanza Province, Luo tribe1.00.0050100See
ZAFSouth Africa Natal Zulu1.00.0050100See
USAUSA South Dakota Lakota Sioux0.0050302See
USAUSA North American Native0.0050187See
USAUSA NMDP Mexican or Chicano0.0049261235See
DEUGermany pop 60.00448862See
DEUGermany DKMS - Austria minority0.00441698See
CZECzech Republic NMDR0.00445099See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00441028See
MEXMexico Mexico City Mestizo pop 20.0043234See
POLPoland DKMS0.004220653See
USAUSA NMDP Alaska Native or Aleut0.00401376See
AUSAustralia New South Wales Caucasian0.0040134See
USAUSA NMDP North American Amerindian0.003935791See
DEUGermany DKMS - United Kingdom minority0.00381043See
DEUGermany DKMS - German donors0.00373456066See
DEUGermany DKMS - Netherlands minority0.00381374See
USAUSA NMDP European Caucasian0.00321242890See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.60.00314335See
USAUSA Eastern European0.0030558See
USAUSA San Antonio Caucasian0.0030222See
ENGEngland North West0.70.0030298See
NLDNetherlands Leiden0.00301305See
NIRIreland Northern0.50.00301000See
FRAFrance French Bone Marrow Donor Registry0.002642623See
MEXMexico Chiapas Lacandon Mayans0.0023218See
KENKenya Nandi0.0020240See
DEUGermany DKMS - Spain minority0.00201107See
ISRIsrael Bukhara Jews0.00042317See
ISRIsrael Ethiopia Jews0.00045928See
ISRIsrael YemenJews0.000415542See
ISRIsrael Iran Jews0.00048153See
ISRIsrael Ashkenazi Jews pop 30.00034625See
ISRIsrael Georgia Jews0.00024471See
ISRIsrael USSR Jews0.000245681See
ISRIsrael USA Jews0.00026058See
ISRIsrael Tunisia Jews0.00029070See
ISRIsrael Argentina Jews0.00014307See
ISRIsrael Poland Jews0.000113871See
ISRIsrael Druze0.00015914See
ISRIsrael Arab pop 20.000112301See
ISRIsrael Iraq Jews0.000113270See
ISRIsrael Morocco Jews0.000136718See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
JPNJapan Hokkaido Ainu0.000050See
MARMorocco Nador Metalsa pop 20.000073See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
AUSAustralia Yuendumu Aborigine0.0000191See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CHNChina North Han0.0000105See
ZMBZambia Lusaka0.000044See
USAUSA Philadelphia Caucasian0.00.0000141See
PHLPhilippines Ivatan0.00.000050See
PRTPortugal Center0.000050See
PRTPortugal South0.000049See
PRTAzores Oriental Islands0.000043See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See

See also higher resolution data of this allele

Allele  Number of Populations 
 A*33:03:01 45 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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