Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 247 time(s) and present in 202 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
STPSao Tome Island Angolar0.244032See
CIVIvory Coast Adiopodoume Akan0.227044See
BFABurkina Faso Rimaibe0.223047See
BFABurkina Faso Mossi0.208053See
STPSao Tome Island Forro0.192066See
GHAGhana Accre Asutuare Akan0.1670429See
MLIMali Bandiagara0.1590138See
USAUSA African American Bethesda24.50.1330187See
ISRIsrael Iran Jews0.13288153See
USAUSA NMDP Caribean Black0.128133328See
USAUSA NMDP African0.121328557See
GHAGhana Ga-Adangbe22.90.1183131See
USAUSA NMDP African American pop 20.1178416581See
USAUSA African American pop 80.1170605See
CMRCameroon Sawa0.115013See
USAUSA African American pop 40.11252411See
CMRCameroon Yaounde0.109092See
CPVCape Verde Southeastern Islands0.107062See
CUBCuba Mixed Race21.40.107042See
UGAUganda Kampala pop 20.1060175See
USAUSA African American0.1060252See
ZMBZambia Lusaka0.102044See
CMRCameroon Baka Pygmy0.100010See
GNBGuinea Bissau0.100065See
KENKenya, Nyanza Province, Luo tribe19.00.1000100See
CMRCameroon Beti0.0980174See
ZWEZimbabwe Harare Shona0.0930230See
IRNIran Baloch0.0910100See
CPVCape Verde Northwestern Islands0.089062See
KENKenya Nandi0.0880240See
USAUSA New Mexico Canoncito Navajo0.085042See
CMRCameroon Bamileke0.084077See
TZATanzania Maasai14.70.0838336See
BFABurkina Faso Fulani0.082049See
ISRIsrael YemenJews0.071315542See
KENKenya Luo0.0680265See
CMRCameroon Bakola Pygmy12.00.061950See
SENSenegal Niokholo Mandenka0.0530165See
UGAUganda Kampala0.0500161See
SDNSudan Mixed9.50.0480200See
CHESwitzerland Geneva pop 20.04331267See
ISRIsrael Ethiopia Jews0.03775928See
GEOGeorgia Tibilisi Kurd0.034031See
BRABrazil Puyanawa6.70.0330150See
USAUSA NMDP Caribean Indian0.032014339See
USAUSA Hispanic0.0300234See
ISRIsrael Iraq Jews0.029713270See
MEXMexico Guadalajara Mestizo pop 20.0290103See
USAUSA NMDP Caribean Hispanic0.0287115374See
CHESwitzerland Zurich0.02574875See
IRNIran Saqqez-Baneh Kurds0.025060See
ISRIsrael Arab Druze0.0250101See
IRNIran Kurd pop 20.025060See
ZAFSouth Africa Worcester5.00.0250159See
CHESwitzerland Aargau-Solothurn0.02421838See
JORJordan Amman0.0240146See
MEXMexico Veracruz Xalapa4.80.023884See
CHESwitzerland St Gallen0.02362113See
ISRIsrael Druze0.02365914See
TUNTunisia pop 30.0230104See
RUSRussia Tuva pop 20.0220169See
BRABrazil Mixed0.0220108See
CUBCuba Caucasian4.30.021070See
ESPSpain Majorca and Minorca0.021090See
MARMorocco Atlantic Coast Chaouya0.021098See
MARMorocco Settat Chaouya4.20.021098See
ISRIsrael Arab pop 20.020712301See
SGPSingapore Javaneses0.020051See
CHESwitzerland Basel0.01971888See
USAUSA NMDP Hispanic South or Central American0.0195146714See
COLColombia Bogotá Cord Blood3.80.01951463See
INDIndia Mumbai Maratha0.019091See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0180146See
CHESwitzerland Lugano0.01801169See
BRABrazil Terena3.40.017060See
BRABrazil Belo Horizonte Caucasian3.20.016095See
FRAFrance Southeast3.10.0160130See
USAUSA Hispanic pop 20.01551999See
NICNicaragua Managua3.00.0151339See
CAFCentral African Republic Mbenzele Pygmy3.00.015136See
GTMGuatemala Mayan0.0150132See
SAUSaudi Arabia Guraiat and Hail2.90.0150213See
ZAFSouth Africa Natal Zulu3.00.0150100See
CHESwitzerland Bern0.01423545See
MARMorocco Nador Metalsa pop 20.014073See
DEUGermany DKMS - Portugal minority0.01331176See
GEOGeorgia Svaneti Region Svan0.013080See
USAUSA San Diego2.20.0130496See
PRTAzores Oriental Islands0.013043See
USAUSA South Texas Hispanic0.0130194See
MEXMexico Mexico City Mestizo pop 20.0128234See
USAUSA NMDP Mexican or Chicano0.0123261235See
DEUGermany DKMS - Spain minority0.01221107See
USAUSA NMDP Middle Eastern or North Coast of Africa0.012170890See
USAUSA North American Native0.0110187See
USAUSA NMDP American Indian South or Central America0.01105926See
PRTPortugal North0.011046See
ESPSpain Catalonia Girona0.011088See
MEXMexico Mexico City Tlalpan2.10.0106330See
TUNTunisia Gabes0.010595See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.00.01014335See
ISRIsrael Tunisia Jews0.01019070See
INDIndia Andhra Pradesh Golla0.0100111See
CHLChile Santiago Mixed2.00.010070See
CHNChina Yunnan Hani0.0100150See
PRTPortugal Center0.010050See
NCLNew Caledonia0.010065See
AREUnited Arab Emirates Abu Dhabi0.009652See
COLColombia North Wiwa El Encanto0.009652See
DEUGermany DKMS - Italy minority0.00951159See
FRAFrance French Bone Marrow Donor Registry0.009142623See
ISRIsrael Morocco Jews0.009036718See
PRTPortugal Azores Terceira Island1.80.0088130See
CHESwitzerland Sion0.0082832See
CHESwitzerland Graubunden0.0081759See
IRNIran Gorgan0.008064See
PRTAzores Terceira Island0.0080130See
USAUSA European American pop 20.00801245See
ISRIsrael Bukhara Jews0.00802317See
USAUSA NMDP North American Amerindian0.007335791See
USAUSA Philadelphia Caucasian1.50.0070141See
MEXMexico Oaxaca Zapotec0.007090See
ITAItaly pop 50.0070975See
HRVCroatia pop 40.00684000See
DEUGermany DKMS - France minority0.00681406See
CHESwitzerland Luzern0.00631553See
DEUGermany DKMS - Turkey minority0.00614856See
ITAItaly Bergamo1.00.0060101See
SGPSingapore SGVP Malay MAS0.006089See
TUNTunisia Ghannouch0.006082See
DEUGermany DKMS - Croatia minority0.00562057See
DEUGermany DKMS - Netherlands minority0.00551374See
CHESwitzerland Lausanne0.0052993See
IRNIran Tabriz Azeris0.005297See
INDIndia Delhi pop 21.10.005090See
FRAFrance Corsica Island0.0050100See
ITAItaly Sardinia pop30.0050100See
CHNChina Guangzhou Han0.0050106See
CHNChina Guangdong Province Meizhou Han0.0050100See
ESPSpain Andalusia Romani0.005099See
USAUSA San Francisco Caucasian0.0050220See
USAUSA South Dakota Lakota Sioux0.0050302See
MEXMexico Chiapas Lacandon Mayans0.0046218See
ISRIsrael Kavkazi Jews0.00442840See
USAUSA NMDP Hawaiian or other Pacific Islander0.004011499See
USAUSA Caucasian pop 20.0040265See
USAUSA Caucasian Bethesda0.80.0040307See
MEXMexico Mexico City Mestizo population0.0035143See
DEUGermany pop 60.00358862See
DEUGermany DKMS - Austria minority0.00351698See
ISRIsrael USA Jews0.00356058See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00341028See
DEUGermany DKMS - Greece minority0.00341894See
USAUSA NMDP European Caucasian0.00341242890See
DEUGermany DKMS - United Kingdom minority0.00341043See
DEUGermany pop 80.003339689See
DEUGermany DKMS - German donors0.00323456066See
USAUSA San Antonio Caucasian0.0030222See
ISRIsrael Argentina Jews0.00294307See
USAUSA Caucasian pop 40.00281070See
CHNChina Jiangsu Province Han0.0023334See
ISRIsrael Poland Jews0.002213871See
CZECzech Republic NMDR0.00215099See
ISRIsrael Ashkenazi Jews pop 30.00214625See
IRLIreland South0.40.0020250See
USAUSA Eastern European0.0020558See
USAUSA NMDP Alaska Native or Aleut0.00201376See
USAUSA Alaska Yupik0.0020252See
NIRIreland Northern0.40.00201000See
NLDNetherlands Leiden0.00201305See
POLPoland DKMS0.001620653See
ISRIsrael USSR Jews0.001645681See
USAUSA NMDP Southeast Asian0.001427978See
ISRIsrael Libya Jews0.00133739See
USAUSA NMDP South Asian Indian0.0013185391See
LKASri Lanka Colombo0.30.0010714See
ISRIsrael Georgia Jews0.00094471See
USAUSA NMDP Filipino0.000850614See
USAUSA Asian pop 20.00091772See
INDIndia Tamil Nadu0.00062492See
DEUGermany DKMS - Romania minority0.00041234See
HKGHong Kong Chinese cord blood registry0.00043892See
USAUSA NMDP Japanese0.000324582See
USAUSA NMDP Chinese0.000399672See
DEUGermany DKMS - China minority0.00041282See
HKGHong Kong Chinese BMDR0.00037595See
USAUSA NMDP Vietnamese0.000243540See
USAUSA NMDP Korean0.000177584See
JPNJapan pop 160.000118604See
MEXMexico Mestizo0.00.000041See
MEXMexico Oaxaca Mixtec0.0000103See
KORSouth Korea pop 30.0000485See
INDIndia West Coast Parsi0.000050See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
HKGHong Kong Chinese0.00.0000569See
CZECzech Republic0.0000106See
ESPSpain Gipuzkoa Basque0.0000100See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
AUSAustralia Yuendumu Aborigine0.0000191See
AUSAustralia New South Wales Caucasian0.0000134See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
USAUSA Asian0.0000358See
ZAFSouth Africa Caucasians0.0000102See
SGPSingapore SGVP Chinese CHS0.000096See
SGPSingapore SGVP. Indian INS0.000086See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
PHLPhilippines Ivatan0.00.000050See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Wanigela Keapara0.000066See
SCOScotland Orkney0.00.000099See
SGPSingapore Chinese0.00.0000149See
PRTAzores Central Islands0.000059See
PRTPortugal South0.000049See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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