Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 148 time(s) and present in 101 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0230146See
ISRIsrael Kavkazi Jews0.02102840See
MEXMexico Sonora Seri0.015034See
AREUnited Arab Emirates Pop 10.0120570See
CMRCameroon Beti0.0110174See
ISRIsrael Iraq Jews0.009413270See
ISRIsrael Arab pop 20.009412301See
GEOGeorgia Tibilisi0.0090109See
RUSRussia Tuva pop 20.0080169See
SDNSudan Mixed1.50.0080200See
SAUSaudi Arabia pop 6 (G)0.007528927See
ISRIsrael Ethiopia Jews0.00665928See
RUSRussia Belgorod region1.30.0065153See
CMRCameroon Bamileke0.006077See
ISRIsrael Arab Druze0.0050101See
IRNIran Baloch0.0050100See
MNGMongolia Khalkha0.0050200See
CHESwitzerland Aargau-Solothurn0.00401838See
LBYLibya Cyrenaica0.0040118See
MEXMexico Mexico City Mestizo population0.0035143See
UGAUganda Kampala pop 20.0030175See
ITAItaly pop 50.0030975See
JORJordan Amman0.0030146See
DEUGermany DKMS - Italy minority0.00301159See
DEUGermany DKMS - Greece minority0.00291894See
USAUSA NMDP Middle Eastern or North Coast of Africa0.002870890See
ISRIsrael YemenJews0.002715542See
CHESwitzerland Luzern0.00251553See
ESPSpain, Canary Islands, Gran canaria island0.50.0023215See
ZWEZimbabwe Harare Shona0.0020230See
USAUSA Hispanic0.0020234See
USAUSA Mexican American Mestizo0.0020553See
KENKenya Nandi0.0020240See
KENKenya Luo0.0020265See
MKDMacedonia pop 40.0020216See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
ISRIsrael USSR Jews0.002045681See
ISRIsrael Argentina Jews0.00174307See
ISRIsrael Iran Jews0.00178153See
RUSRussia Karelia0.00141075See
BRABrazil Barra Mansa Rio State Caucasian0.0012405See
CHESwitzerland Zurich0.00124875See
USAUSA Hispanic pop 20.00131999See
ISRIsrael Poland Jews0.001113871See
DEUGermany DKMS - Turkey minority0.00114856See
USAUSA NMDP African0.001128557See
ISRIsrael Ashkenazi Jews pop 30.00114625See
ISRIsrael USA Jews0.00116058See
BRABrazil Rio de Janeiro Caucasian0.0010521See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
USAUSA NMDP Caribean Indian0.001014339See
ISRIsrael Druze0.00095914See
HRVCroatia pop 40.00094000See
DEUGermany DKMS - Austria minority0.00091698See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00101028See
USAUSA NMDP Caribean Hispanic0.0009115374See
DEUGermany DKMS - Romania minority0.00081234See
DEUGermany pop 80.000839689See
ISRIsrael Georgia Jews0.00084471See
ISRIsrael Tunisia Jews0.00089070See
USAUSA NMDP Hispanic South or Central American0.0007146714See
DEUGermany DKMS - France minority0.00071406See
DEUGermany DKMS - Netherlands minority0.00071374See
CZECzech Republic NMDR0.00075099See
COLColombia Bogotá Cord Blood0.10.00071463See
USAUSA NMDP Vietnamese0.000643540See
USAUSA NMDP Mexican or Chicano0.0006261235See
DEUGermany pop 60.00078862See
DEUGermany DKMS - German donors0.00063456066See
ISRIsrael Morocco Jews0.000536718See
MYSMalaysia Peninsular Malay0.10.0005951See
DEUGermany DKMS - Croatia minority0.00052057See
ENGEngland Manchester0.10.00051640See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00054335See
USAUSA NMDP Southeast Asian0.000527978See
ISRIsrael Libya Jews0.00043739See
DEUGermany DKMS - Portugal minority0.00041176See
POLPoland DKMS0.000520653See
USAUSA NMDP European Caucasian0.00041242890See
RUSRussia Nizhny Novgorod, Russians0.10.00031510See
DEUGermany DKMS - China minority0.00041282See
CHNChina Zhejiang Han0.00031734See
INDIndia West UCBB0.10.00035829See
USAUSA NMDP Caribean Black0.000233328See
USAUSA NMDP Filipino0.000250614See
POLPoland BMR0.00.000223595See
USAUSA NMDP South Asian Indian0.0002185391See
INDIndia Tamil Nadu0.00022492See
USAUSA Asian pop 20.00031772See
USAUSA NMDP African American pop 20.0002416581See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
CHNChina Hubei Han0.00.00013732See
USAUSA NMDP Hawaiian or other Pacific Islander0.000111499See
USAUSA NMDP North American Amerindian0.000135791See
USAUSA NMDP Chinese0.000199672See
HKGHong Kong Chinese BMDR0.00017595See
USAUSA NMDP Korean0.000077584See
USAUSA North American Native0.0000187See
USAUSA Asian0.0000358See
USAUSA European American pop 20.00001245See
USAUSA African American pop 80.0000605See
USAUSA African American pop 40.00002411See
USAUSA Philadelphia Caucasian0.00.0000141See
ZMBZambia Lusaka0.000044See
UGAUganda Kampala0.0000161See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
MEXMexico Mestizo0.00.000041See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
NLDNetherlands Leiden0.00001305See
HKGHong Kong Chinese0.00.0000569See
NIRIreland Northern0.00.00001000See
ITAItaly Bergamo0.00.0000101See
MLIMali Bandiagara0.0000138See
KORSouth Korea pop 30.0000485See
BFABurkina Faso Rimaibe0.000047See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina North Han0.0000105See
ENGEngland Sheffield0.00.00004755See
ENGEngland Leeds0.00.00005024See
FRAFrance Grenoble, Nantes and Rennes0.00006094See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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