Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 
   

DRB1*04:08

 
Allele reported 262 time(s) and present in 182 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
CZECzech Republic Gypsy11.80.060834See
RUSRussia Siberia Lower Yenisey Ket0.060017See
RUSRussia Siberia Khabarovsk Evenki0.060025See
USAUSA South Dakota Sioux0.0360101See
USAUSA Mexican American Mestizo pop 30.0300116See
MEXMexico Mazahua0.030065See
CHNChina Beijing and Xian0.0290171See
CHNChina Urumqi Uyghur5.30.026057See
CHNChina Urumqi Kazak0.024042See
PERPeru Quechua0.023044See
SWESweden Northern Sami0.0210154See
SVNSlovenia4.00.0202100See
FINFinland pop20.0200150See
CANCanada British Columbia Penutian0.019026See
ISRIsrael Ashkenazi Jews pop 20.0190132See
MEXMexico Oaxaca Zapotec0.017090See
INDIndia Northeast Lachung0.017058See
RUSRussia Transbaikal Territory Buryats3.00.0170150See
MNGMongolia Khalkha pop 20.0150202See
ITAItaly Rome3.00.0150100See
ESPSpain Northwest Lugo2.80.0141145See
SCOScotland Orkney2.90.014099See
USAUSA Hawaii0.013039See
MNGMongolia Ulaanbaatar Khalkha0.012041See
BRABrazil Southeast Mulatto2.40.012042See
RUSRussia Tuva pop30.011044See
FINFinland0.011091See
USAUSA South Dakota Lakota Sioux0.0100302See
TWNTaiwan Aborigine pop 20.010048See
FRAFrance Rennes pop 30.0100200See
MTQMartinique0.0100100See
USAUSA Caucasian Houston2.00.0100194See
ARMArmenia combined Regions0.0100100See
ARGArgentina Buenos Aires1.90.0100466See
PRTPortugal Center0.010050See
USAUSA San Francisco Caucasian0.0090220See
NLDNetherlands1.80.0090447See
MEXMexico Huasteca Region Teenek0.009055See
NCLNew Caledonia0.008065See
JAMJamaica0.0080132See
JPNJapan pop 111.60.008062See
POLPoland0.0080200See
CHNChina Urumqi Han0.008059See
SAUSaudi Arabia Guraiat and Hail1.50.0080213See
IRLIreland South1.60.0080250See
NLDNetherlands UMCU1.60.007864See
ISRIsrael Ashkenazi Jews pop 30.00734625See
DEUGermany DKMS - Austria minority0.00711698See
RUSRussia Karelia0.00701075See
CUBCuba Mixed0.007078See
CHNChina Beijing Shijiazhuang Tianjian Han0.0070618See
SVNSlovenia pop 21.40.0070140See
IRNIran Fars Parsi0.007073See
BOLBolivia Quechua0.007080See
USAUSA Caucasian1.40.007061655See
GTMGuatemala Mayan0.0070132See
BRABrazil South Caucasian0.006973See
DEUGermany DKMS - Portugal minority0.00641176See
POLPoland DKMS0.006020653See
LKASri Lanka Colombo1.10.0060714See
MEXMexico Veracruz1.20.006084See
MNGMongolia Tarialan Khoton0.006085See
MNGMongolia Hoton0.006085See
PERPeru Lamas City Lama0.006083See
LBNLebanon Yuhmur0.006082See
ESPSpain North Cantabria0.006083See
VNMVietnam HoaBinh Muong0.006083See
USAUSA Colorado Univ Cord Blood Bank African American0.0060261See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00603830See
ETHEthiopia Oromo0.006083See
MKDMacedonia pop 20.006080See
USAUSA Caucasian pop 40.00581070See
CZECzech Republic NMDR0.00545099See
DEUGermany pop 60.00548862See
DEUGermany pop 80.005139689See
DEUGermany DKMS - Spain minority0.00521107See
DEUGermany DKMS - France minority0.00501406See
ENGEngland North West1.00.0050298See
CZECzech Republic pop 21.00.005099See
GRCGreece pop 40.005098See
USAUSA Italy Ancestry0.0050273See
ZAFSouth Africa Caucasians0.0050102See
ITAItaly North pop 31.10.005097See
ITAItaly Bergamo1.00.0050101See
ETHEthiopia Amhara0.005098See
CZECzech Republic0.0050106See
MNGMongolia Khalkha0.0050200See
USAUSA Colorado Univ Cord Blood Bank Asian0.0050100See
VNMVietnam Hanoi Kinh0.0050103See
CHNChina Lijiang Naxi0.0050100See
ESPSpain North Cabuerniga0.005095See
ESPSpain Pas Valley0.005088See
RUSRussia Tuva0.0050190See
FRAFrance West1.00.0050100See
INDIndia Tamil Nadu0.00462492See
ISRIsrael Ethiopia Jews0.00445928See
PRTPortugal Azores Terceira Island0.90.0044130See
CHLChile Santiago0.0042920See
COLColombia Bogotá Cord Blood0.80.00411463See
USAUSA Spain Ancestry0.0040279See
NLDNetherlands Leiden0.00401305See
ESPSpain Barcelona0.90.0040941See
BRABrazil North East Mixed0.0040205See
CHNChina Wuhan0.80.0040121See
FRAFrance Southeast0.80.0040130See
PRTAzores Terceira Island0.0040130See
TURTurkey pop 10.0040250See
USAUSA NMDP European Caucasian0.00391242890See
USAUSA Hispanic pop 20.00351999See
DEUGermany DKMS - United Kingdom minority0.00341043See
HRVCroatia pop 40.00314000See
FRAFrance South0.0030350See
ECUEcuador Cayapa0.0030183See
DEUGermany Essen0.60.0030174See
MKDMacedonia pop 10.0030158See
USAUSA Caucasian Bethesda0.60.0030307See
RUSRussia Tuva pop 20.0030169See
PRTMadeira0.0030185See
KORSouth Korea pop 110.0030149See
GAZGaza Palestinians0.0030165See
DEUGermany DKMS - Turkey minority0.00284856See
USAUSA NMDP North American Amerindian0.002535791See
ISRIsrael Poland Jews0.002413871See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00241028See
BRABrazil Paraná Caucasian0.50.0023641See
USAUSA San Antonio Caucasian0.0023222See
USAUSA NMDP South Asian Indian0.0023185391See
ISRIsrael Arab pop 20.002112301See
DEUGermany DKMS - Netherlands minority0.00221374See
DEUGermany DKMS - Greece minority0.00211894See
MEXMexico Mexico City Mestizo pop 20.0021234See
BRABrazil Mato Grosso do Sul0.0020203See
NIRIreland Northern0.30.00201000See
CHNChina Jiangsu Han0.00203238See
USAUSA Alaska Yupik0.0020252See
ESPSpain Granada0.0020280See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00201058See
ITAItaly pop 50.0020975See
USAUSA NMDP American Indian South or Central America0.00205926See
USAUSA Eastern European0.0020558See
ISRIsrael USA Jews0.00206058See
DEUGermany DKMS - China minority0.00201282See
ISRIsrael USSR Jews0.001845681See
CHNChina Jiangsu Province Han0.0018334See
USAUSA NMDP Middle Eastern or North Coast of Africa0.001870890See
DEUGermany DKMS - Croatia minority0.00172057See
DEUGermany DKMS - Romania minority0.00161234See
USAUSA NMDP Southeast Asian0.001627978See
USAUSA NMDP Hispanic South or Central American0.0016146714See
USAUSA Asian pop 20.00141772See
DEUGermany DKMS - Italy minority0.00131159See
USAUSA NMDP Caribean Hispanic0.0011115374See
KORSouth Korea pop 100.00114128See
USAUSA NMDP Mexican or Chicano0.0011261235See
KORSouth Korea pop 60.0010800See
CHNChina Marrow Donor Registry0.0010600See
KORSouth Korea pop 30.0010485See
ITAItaly pop 40.20.00104575See
USAUSA Mexican American Mestizo0.0010553See
ITAItaly Sardinia pop20.20.00101129See
USAUSA NMDP Vietnamese0.001043540See
ISRIsrael Argentina Jews0.00084307See
ISRIsrael Iran Jews0.00088153See
USAUSA NMDP African American pop 20.0006416581See
USAUSA African American pop 40.00062411See
ISRIsrael Georgia Jews0.00064471See
ISRIsrael Bukhara Jews0.00042317See
USAUSA NMDP Korean0.000477584See
USAUSA NMDP Caribean Black0.000433328See
ISRIsrael Kavkazi Jews0.00042840See
ISRIsrael Druze0.00035914See
USAUSA NMDP Chinese0.000399672See
USAUSA NMDP African0.000328557See
USAUSA NMDP Hawaiian or other Pacific Islander0.000211499See
USAUSA NMDP Filipino0.000250614See
ISRIsrael Iraq Jews0.000113270See
ISRIsrael Tunisia Jews0.00019070See
ISRIsrael Morocco Jews0.000136718See
HKGHong Kong Chinese BMDR0.00017595See
USAUSA NMDP Japanese0.000124582See
ISRIsrael YemenJews0.000015542See
POLPoland (G)0.00.000023595See
INDIndia Northeast Mech0.000063See
INDIndia Northeast Rajbanshi0.000098See
DEUGermany pop 30.00.0000111See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
PRYParaguay Lengua0.000017See
IRNIran Yazd Zoroastrian0.000065See
RUSRussia Siberia Dudinka Nganasan0.000024See
USAUSA Philadelphia Caucasian0.00.0000141See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Irkutsk Tofalar0.000043See
RUSRussia Siberia Kushun Buryat0.000025See
RUSRussia Siberia Khanty Mansi0.000068See
RUSRussia Siberia Ulchi0.000073See
RUSRussia Siberia Negidal0.000035See
PNGPapua New Guinea East New Britain Tolai0.000048See
WSMSamoa West0.000022See
BORBorneo Bandjarmasin0.000021See
PNGPapua New Guinea Highland pop20.000028See
ISRIsrael Libyan Jews0.0000119See
ISRIsrael Iranian Jews0.0000101See
ISRIsrael Ethiopian Jews0.0000122See
ISRIsrael Yemenite Jews0.000076See
ISRIsrael Arab0.0000109See
JPNJapan Hyogo Osaka and Nagano0.0000195See
TUNTunisia Jerba Berber0.000055See
CHNChina Harbin Manchu0.0000172See
CHNChina Harbin Korean0.0000201See
DNKDenmark0.000055See
LBNLebanon Kafar Zubian0.000094See
LBNLebanon Niha el Shouff0.000061See
MYSMalaysia0.000074See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
IDNIndonesia Singaporean0.000050See
WSMSamoa0.000029See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
PHLPhilippines0.000034See
MEXMexico Highlands Mestizos0.00.0000160See
MEXMexico Nuevo Leon Mestizo0.00.000040See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
MNGMongolia Oold0.0000104See
MNGMongolia Tsaatan0.0000144See
USAUSA South Texas Hispanic0.0000194See
KORSouth Korea pop 20.00.0000207See
PRTPortugal North0.000046See
PRTPortugal South0.000049See
CANCanada British Columbia Athabaskan0.000062See
MEXMexico Oaxaca Mixtec0.0000103See
ESPSpain Murcia0.0000173See
BRABrazil Guarani Nandeva0.000086See
BGRBulgaria0.000055See
CHNChina Xinjiang Province Uyghur0.000092See
COLColombia Bogota and Medellin Mestizo0.000065See
CHNChina Hong Kong and Singapore0.0000135See
FJIFiji Viti Levu Island0.000057See
BRABrazil East Amazon0.000041See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PRYParaguay Aché0.000087See
DZAAlgeria pop 20.00.0000106See
ISRIsrael Moroccan Jews0.0000113See
INDIndia Northeast Kayastha0.0000190See
INDIndia Northeast Mathur0.0000155See
INDIndia Northeast Rastogi0.0000196See
INDIndia Northeast Vaish0.0000198See
INDIndia Northeast Shia0.0000190See
INDIndia Northeast Sunni0.0000188See
BRABrazil Southeast Caucasian0.00.0000103See
USAUSA Caucasian Pittsburgh0.00.0000177See
CAFCentral African Republic Aka Pygmy0.00.000093See
CODCongo Kinshasa Bantu0.00.000090See
USAUSA African American Bethesda0.00.0000187See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See

Frequency data at lower resolution for this allele can be found in links below


Allele  Number of Populations 

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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