Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 238 time(s) and present in 139 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.070057See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.060032See
FJIFiji Viti Levu Island0.053057See
COLColombia Northwest Tule0.052029See
CHNChina Lijiang Naxi0.0430100See
CANCanada British Columbia Athabaskan0.040062See
RUSRussia Sakhalin Island Nivkhi0.038053See
USAUSA Alaska Yupik0.0360252See
CHNChina Guizhou Province Miao0.036085See
JPNJapan Hokkaido Wajin7.00.035671See
PNGPapua New Guinea Highland pop20.035028See
CHNChina Yunnan Province Naxi0.0340118See
PNGPapua New Guinea Highland0.029094See
JPNJapan Nagano5.30.026857See
AUSAustralia Cape York Peninsula Aborigine0.0250103See
JPNJapan Kyoto and Osaka0.0240165See
NICNicaragua Managua4.80.0240339See
JPNJapan pop 64.70.0237129See
JPNJapan Hyogo3.10.023032See
JPNJapan pop 160.021518604See
JPNJapan pop 170.02153078See
JPNJapan Hyogo Osaka and Nagano0.0200195See
KORSouth Korea pop 110.0200149See
MNGMongolia Khalkha pop 20.0200202See
JPNJapan pop 43.80.0190525See
USAUSA NMDP Japanese0.018224582See
JPNJapan pop 20.0180916See
JPNJapan pop 30.01801018See
JPNJapan Central0.0180371See
INDIndia North3.50.017685See
MEXMexico Oaxaca Mixtec0.0150103See
NCLNew Caledonia0.015065See
RUSRussia Siberia Negidal0.014035See
RUSRussia Siberia Irkutsk Tofalar0.012043See
MNGMongolia Ulaanbaatar Khalkha0.012041See
KORSouth Korea pop 22.40.0120207See
KORSouth Korea pop 42.40.0120211See
ARGArgentina Mapuche0.012048See
CHNChina Urumqi Kazak0.012042See
KORSouth Korea pop 60.0110800See
RUSRussia Tuva pop30.011044See
KORSouth Korea pop 100.01044128See
KORSouth Korea pop 30.0100485See
MNGMongolia Oold0.0100104See
MEXMexico Guanajuato and Jalisco Mestizo2.00.0100101See
TWNTaiwan Minnan pop 12.00.0100102See
TWNTaiwan Hakka1.80.009055See
USAUSA Arizona Gila River Amerindian0.0090492See
USAUSA Mexican American Mestizo pop 30.0090116See
MEXMexico Oaxaca Mixe0.009055See
PNGPapua New Guinea East New Britain Rabaul0.009060See
LBNLebanon Niha el Shouff0.009061See
KORSouth Korea pop 10.0090324See
CHNChina Yunnan Province Nu0.0090107See
USAUSA NMDP Korean0.008577584See
CHNChina Yunnan Province Han pop 20.0080129See
CHNChina Yunnan Province Wa0.0080119See
CHNChina Urumqi Han0.008059See
JPNJapan South1.60.0080125See
JPNJapan pop 111.60.008062See
PNGPapua New Guinea Dorogori0.008059See
CHNChina Beijing and Xian0.0070171See
GTMGuatemala Mayan0.0070132See
CUBCuba Mixed0.007078See
USAUSA South Dakota Lakota Sioux0.0070302See
RUSRussia Siberia Ulchi0.007073See
COKCook Islands Rarotonga0.006078See
ARGArgentina Rosario Toba1.20.006086See
MEXMexico Oaxaca Zapotec0.006090See
GRCGreece pop 81.20.006083See
MEXMexico Mixtec0.005097See
NZLNew Zealand Maori0.0050200See
ARGArgentina Buenos Aires1.00.0050466See
CHNChina pop11.00.0050103See
CHNChina Harbin Korean0.0050201See
CHNChina Inner Mongolia Region Ewenki0.005094See
INDIndia Andhra Pradesh Golla0.0050111See
RUSRussia Northwest Slavic0.0050200See
TWNTaiwan Minnan and Hakka0.0050190See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00501058See
USAUSA Hispanic pop 20.00481999See
MEXMexico Mexico City Mestizo pop 20.0043234See
ESPSpain Granada0.0040280See
USAUSA Mexican American Mestizo0.0040553See
RWARwanda Kigali Hutu and Tutsi0.0040281See
USAUSA Asian pop 20.00371772See
USAUSA NMDP Hispanic South or Central American0.0035146714See
COLColombia Bogotá Cord Blood0.70.00341463See
INDIndia Tamil Nadu0.00342492See
ECUEcuador Cayapa0.0030183See
MEXMexico Highlands Mestizos0.60.0030160See
RUSRussia Tuva0.0030190See
RUSRussian Federation - Transbaikal Territory - Buryats1.00.0030150See
ZAFSouth Africa Black0.0030200See
GRCGreece pop 60.0021242See
LKASri Lanka Colombo0.40.0020714See
CHNChina Jiangsu Han0.00203238See
CHNChina Canton Han0.0020264See
BRABrazil Mato Grosso do Sul0.0020203See
USAUSA Colorado Univ Cord Blood Bank African American0.0020261See
TWNTaiwan Han Chinese0.0020504See
USAUSA San Diego0.40.0020496See
USAUSA Italy Ancestry0.0020273See
USAUSA Spain Ancestry0.0020279See
USAUSA NMDP Mexican or Chicano0.0020261235See
DEUGermany DKMS - China minority0.00201282See
CHNChina Jiangsu Province Han0.0018334See
USAUSA NMDP North American Amerindian0.001635791See
USAUSA NMDP Chinese0.001599672See
USAUSA NMDP South Asian Indian0.0015185391See
USAUSA NMDP Southeast Asian0.001427978See
USAUSA NMDP Vietnamese0.001443540See
USAUSA Eastern European0.0010558See
USAUSA Caucasian pop 40.00101070See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
ITAItaly Sardinia pop20.10.00101129See
USAUSA NMDP Filipino0.000850614See
DEUGermany DKMS - Romania minority0.00081234See
DEUGermany DKMS - Turkey minority0.00084856See
BRABrazil Paraná Caucasian0.20.0008641See
HKGHong Kong Chinese cord blood registry0.00063892See
USAUSA African American pop 40.00062411See
HKGHong Kong Chinese BMDR0.00067595See
CHLChile Santiago0.0005920See
DEUGermany DKMS - Italy minority0.00041159See
USAUSA NMDP African0.000428557See
ISRIsrael Arab pop 20.000312301See
USAUSA NMDP Caribean Hispanic0.0003115374See
DEUGermany pop 80.000239689See
USAUSA NMDP Caribean Black0.000133328See
USAUSA NMDP African American pop 20.0001416581See
ISRIsrael Argentina Jews0.00014307See
HRVCroatia pop 40.00014000See
POLPoland DKMS0.000220653See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
USAUSA NMDP European Caucasian0.00011242890See
ISRIsrael USSR Jews0.000045681See
FRAFrance West0.00.0000100See
FRAFrance Rennes pop 30.0000200See
IDNIndonesia Java Yogyakarta Region0.000062See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
IDNIndonesia Singaporean0.000050See
CZECzech Republic0.0000106See
ESPSpain Barcelona0.00.0000941See
ESPSpain Murcia0.0000173See
COKCook Islands0.000050See
COLColombia Bogota and Medellin Mestizo0.000065See
CODCongo Kinshasa Bantu0.00.000090See
CHNChina Yunnan Province Yao0.000066See
CHNChina Yunnan Province Jinuo0.0000109See
CHNChina Urumqi Uyghur0.00.000057See
CHNChina Harbin Manchu0.0000172See
CHNChina Xinjiang Province Uyghur0.000092See
CHNChina Hong Kong and Singapore0.0000135See
CAFCentral African Republic Aka Pygmy0.00.000093See
CANCanada British Columbia Penutian0.000026See
BRABrazil North East Mixed0.0000205See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BRABrazil Southeast Caucasian0.00.0000103See
BRABrazil Southeast Mulatto0.00.000042See
BORBorneo Bandjarmasin0.000021See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
ITAItaly pop 50.0000975See
LBNLebanon Yuhmur0.000082See
LBNLebanon Kafar Zubian0.000094See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
MKDMacedonia pop 10.0000158See
MNGMongolia Khalkha0.0000200See
MNGMongolia Tsaatan0.0000144See
MNGMongolia Tarialan Khoton0.000085See
MNGMongolia Hoton0.000085See
PHLPhilippines Ivatan0.00.000050See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea East New Britain Tolai0.000048See
PNGPapua New Guinea Madang0.000065See
USAUSA Southeast African American0.00.0000112See
USAUSA Caucasian Houston0.00.0000194See
USAUSA Caucasian Pittsburgh0.00.0000177See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00003830See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
TWNTaiwan Aborigine pop 20.000048See
USAUSA Philadelphia Caucasian0.00.0000141See
PRYParaguay Lengua0.000017See
RUSRussia Siberia Kushun Buryat0.000025See
RUSRussia Siberia Khanty Mansi0.000068See
RUSRussia Siberia Sulamai Ket0.000022See
RUSRussia Siberia Polygus Evenk0.000035See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia Khabarovsk Evenki0.000025See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Chukotka Peninsula Chukchi0.000059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
WSMWestern Samoa and Tokelau0.000051See
WSMSamoa West0.000022See
WSMSamoa pop20.000050See
ZAFSouth Africa Caucasians0.0000102See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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