Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 305 time(s) and present in 243 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
USAUSA Arizona Pima pop20.794018See
USAUSA Arizona Gila River Amerindian0.7460492See
COLColombia East Amazon Region Nukak0.650020See
COLColombia Waunana NA-DHS_20 (G)75.00.475020See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.420032See
COLColombia North Eastern Plains Sikuani0.407027See
COLColombia Sierra Nevada de Santa Marta Arsario0.350018See
RUSRussia Siberia Gvaysugi Udege0.350025See
CANCanada British Columbia Athabaskan0.347062See
CANCanada British Columbia Penutian0.346026See
USAUSA New Mexico Canoncito Navajo0.338042See
USAUSA New Mexico Zuni0.320051See
MEXMexico Chihuahua Tarahumara0.318044See
BRABrazil Central Plateau Xavante0.303074See
PRYParaguay/Argentina Guarani NA-DHS_23 (G)60.00.300010See
COLColombia Jaidukama0.288039See
COLColombia West Waunana0.267030See
ARGArgentina Gran Chaco Mataco Wichi0.264049See
COLColombia Northwest Tule0.259029See
ARGArgentina Salta Wichi0.250024See
CRICosta Rica and Panama Mestizo0.240056See
RUSRussia Siberia Chukotka Peninsula Eskimo0.240080See
RUSRussia Siberia North East Kamchatka Koryak0.230092See
USAUSA Alaska Yupik0.2220252See
RUSRussia Siberia Chukotka Peninsula Chukchi0.220059See
ARGArgentina Chubut Tehuelche0.217023See
ARGArgentina Chiriguano37.50.214054See
BRABrazil Guarani Kaiowa0.2060155See
PRYParaguay Lengua0.206017See
BRABrazil Guarani Nandeva0.203086See
COLColombia West Embera0.200020See
CANCanada Ojibwa NA-DHS_4 (G)37.50.187516See
COLColombia Embera NA-DHS_19 (G)35.70.178614See
COLColombia Kogi NA-DHS_17 (G)35.70.178615See
BRABrazil Terena32.20.178060See
USAUSA NMDP Alaska Native or Aleut0.17001376See
MEXMexico Sonora Seri0.167034See
PERPeru Lamas City Lama0.164083See
CHLChile Mapuche0.161566See
COLColombia Sierra Nevada de Santa Marta Kogi pop 30.161031See
CANCanada Chipewyan NA-DHS_2 (G)32.00.160025See
PERPeru Titikaka Lake Uro0.1580105See
PERPeru Titikaka Lake Uros0.1570105See
RUSRussia Siberia Chukchi0.156071See
BOLBolivia La Paz Aymaras0.155087See
USAUSA South Dakota Lakota Sioux0.1510302See
CHLChile Huilliche NA-DHS_14 (G)25.00.150020See
ECUEcuador Cayapa0.1500183See
ARGArgentina Rosario Toba27.90.145086See
PERPeru Quechua0.136044See
COLColombia Sierra Nevada de Santa Marta Kogi0.134042See
ARGArgentina Mapuche0.128048See
BOLBolivia/Peru Quechua NA-DHS_12 (G)23.80.119021See
ARGArgentina Rio Negro Mapuche0.118034See
COLColombia Sierra Nevada de Santa Marta Arhuaco0.1140107See
ARGArgentina Gran Chaco Eastern Toba0.1060135See
CRICosta Rica Cabecar NA-DHS_9 (G)21.10.105319See
ARGArgentina Gran Chaco Western Toba Pilaga0.093019See
CRICosta Rica Amerindians (G)15.10.0920125See
USAUSA South Dakota Sioux0.0890101See
RUSRussia Siberia Negidal0.086035See
BRABrazil East Amazon0.085041See
COLColombia Bogota and Medellin Mestizo0.085065See
CANCanada Cree NA-DHS_3 (G)16.70.083318See
COLColombia Guajira Peninsula Wayuu0.080088See
BOLBolivia Quechua0.079769See
COLColombia North Wiwa El Encanto0.076952See
BOLBolivia/Chile Aymara NA-DHS_13 (G)15.00.075020See
MEXMexico Mayan pop 20.0740163See
RUSRussia Siberia Eskimo0.074070See
AUSAustralia Cape York Peninsula Aborigine0.0710103See
COLColombia Wayuu NA-DHS_15 (G)13.30.066715See
RUSRussia Sakhalin Island Nivkhi0.066053See
MEXMexico Veracruz Xalapa13.10.065584See
USAUSA NMDP North American Amerindian0.063535791See
USAUSA Mexican American Mestizo pop 30.0600116See
MEXMexico Chiapas Lacandon Mayans0.0573218See
MEXMexico San Vicente Tancuayalab Teenek/Huastecos0.056653See
MEXMexico Huasteca Region Teenek0.056055See
GTMGuatemala Kaqchikel NA-DHS_8 (G)10.50.052619See
MEXMexico Zapotec NA-DHS_7 (G)10.50.052620See
PRYParaguay Aché0.052087See
MEXMexico Chihuahua Chihuahua City Pop 210.20.051188See
MEXMexico Mixe NA-DHS_6 (G)10.00.050020See
AUSAustralia Kimberly Aborigine0.049041See
MEXMexico Oaxaca Mixtec0.0490103See
VENVenezuela Sierra de Perija Yucpa0.046073See
MEXMexico Oaxaca Zapotec0.045090See
MEXMexico Mexico City Mestizo pop 30.0450256See
MEXMexico Mexico City Tlalpan8.80.0439330See
BRABrazil Puyanawa8.70.0430150See
USAUSA Southern California Mestizo8.20.041873See
BRABrazil South Caucasian0.041773See
PRYParaguay/Argentina Ache NA-DHS_24 (G)8.30.041713See
COLColombia Zenu NA-DHS_18 (G)8.30.041716See
GTMGuatemala Mayan0.0410132See
RUSRussia Siberia Ulchi0.041073See
NICNicaragua Managua7.50.0404339See
USAUSA NMDP American Indian South or Central America0.04005926See
COLColombia Bogotá Cord Blood7.40.03831463See
MEXMexico Highlands Mestizos7.50.0380160See
CHLChile Santiago0.0379920See
MEXMexico Oaxaca Mixe0.036055See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.03501058See
MEXMexico Mazatecan0.035089See
MEXMexico Mayan0.033016See
COLColombia Sierra Nevada de Santa Marta Ijka pop 20.033030See
USAUSA Mexican American Mestizo0.0320553See
COLColombia Inga NA-DHS_11 (G)6.30.031216See
MEXMexico Oaxaca Jamiltepec Mixtec0.031096See
MEXMexico Mixtec0.031097See
COLColombia Arhuaco NA-DHS_16 (G)5.90.029417See
NICNicaragua Mestizo (G)5.80.0290155See
AUSAustralia Yuendumu Aborigine0.0290191See
INDIndia Northeast Rastogi0.0280196See
CRICosta Rica Guaymi NA-DHS_10 (G)5.60.027818See
USAUSA NMDP Hispanic South or Central American0.0256146714See
CHLChile Santiago Mixed5.00.025370See
ISRIsrael Ashkenazi Jews0.025080See
BRABrazil Southeast Caucasian4.80.0240103See
USAUSA NMDP Mexican or Chicano0.0238261235See
USAUSA Hispanic pop 20.02381999See
MEXMexico Mexico City Mestizo pop 20.0235234See
CRICosta Rica Central Valley Mestizo (G)4.00.0200221See
CHNChina Harbin Manchu pop 20.020050See
RUSRussia Siberia Khabarovsk Evenki0.020025See
MEXMexico Guanajuato and Jalisco Mestizo4.00.0200101See
CRICosta Rica Guanacaste Mestizo (G)3.60.0180110See
INDIndia Northeast Shia0.0180190See
INDIndia Northeast Vaish0.0170198See
COLColombia Providencia Island African0.017030See
DZAAlgeria Oran0.0150100See
RUSRussia Tuva0.0150190See
BRABrazil North East Mixed0.0150205See
BRABrazil Kaingang0.0150235See
ARGArgentina Buenos Aires2.90.0140466See
USAUSA Spain Ancestry0.0140279See
RUSRussia Tuva pop 20.0130169See
BRABrazil Southeast Mixed Race2.40.012042See
MEXMexico Nuevo Leon Mestizo2.50.012040See
JPNJapan Aichi2.20.011050See
CHNChina Lijiang Naxi0.0110100See
INDIndia Northeast Kayastha0.0110190See
BRABrazil Mato Grosso do Sul0.0100203See
USAUSA South Texas Hispanic0.0100194See
MNGMongolia Khalkha0.0100200See
MNGMongolia Khalkha pop 20.0100202See
RUSRussia Bering Island Aleuts0.0096104See
BRABrazil Paraná Caucasian1.90.0094641See
MEXMexico Sinaloa Capomos Mayo Yoremes0.008360See
COLColombia Barranquilla0.0080188See
INDIndia Northeast Sunni0.0080188See
INDIndia Northeast Mathur0.0070155See
INDIndia Uttar Pradesh0.0070202See
FINFinland pop20.0070150See
RUSRussia Transbaikal Territory Buryats1.00.0070150See
LBNLebanon pop 20.0060191See
ITAItaly North Pavia0.006081See
ISRIsrael Non Ashkenazi Jews0.006080See
USAUSA NMDP Caribean Hispanic0.0055115374See
USAUSA NMDP Caribean Indian0.005014339See
GRCGreece pop 40.005098See
CHNChina pop11.00.0050103See
BRABrazil Guarani M bya0.005093See
CHNChina Xinjiang Province Uyghur0.005092See
KORSouth Korea pop 21.00.0050207See
BRABrazil Mixed0.0050108See
JPNJapan pop 60.80.0040129See
INDIndia Lucknow0.80.0040123See
CHNChina Jiangsu Province Han0.0035334See
VNMVietnam Hanoi Kinh pop 20.0030170See
USAUSA African American pop 30.0030564See
CHNChina Beijing and Xian0.0030171See
USAUSA Caucasian Bethesda0.60.0030307See
JPNJapan Hyogo Osaka and Nagano0.0030195See
KORSouth Korea pop 40.50.0025211See
USAUSA San Antonio Caucasian0.0023222See
USAUSA Colorado Univ Cord Blood Bank African American0.0020261See
TURTurkey pop 10.0020250See
THAThailand Northeast0.002066See
JPNJapan pop 40.40.0020525See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
USAUSA San Diego0.40.0020496See
CHNChina Inner Mongolia Autonomous Region Northeast0.40.0020496See
CHESwitzerland Graubunden0.0018759See
CHESwitzerland St Gallen0.00142113See
INDIndia Tamil Nadu0.00102492See
LKASri Lanka Colombo0.30.0010714See
THAThailand Northeast pop 20.0010400See
TWNTaiwan pop 20.0010364See
KORSouth Korea pop 60.0010800See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
JPNJapan pop 30.00101018See
JPNJapan pop 20.0010916See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00103830See
ITAItaly Central0.0010380See
DEUGermany DKMS - Spain minority0.00091107See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.20.00094335See
USAUSA NMDP African American pop 20.0008416581See
USAUSA NMDP African0.000728557See
CHESwitzerland Geneva pop 20.00071267See
USAUSA NMDP Caribean Black0.000733328See
USAUSA NMDP Southeast Asian0.000727978See
USAUSA NMDP Hawaiian or other Pacific Islander0.000611499See
JPNJapan pop 160.000618604See
USAUSA African American pop 40.00062411See
ISRIsrael Argentina Jews0.00064307See
CHESwitzerland Luzern0.00051553See
CHESwitzerland Lugano0.00051169See
USAUSA Caucasian0.10.000561655See
ESPSpain Barcelona0.10.0005941See
USAUSA NMDP Filipino0.000550614See
USAUSA NMDP South Asian Indian0.0004185391See
CHESwitzerland Basel0.00041888See
DEUGermany DKMS - France minority0.00041406See
USAUSA NMDP Korean0.000477584See
USAUSA NMDP European Caucasian0.00031242890See
DEUGermany DKMS - China minority0.00041282See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000370890See
USAUSA NMDP Vietnamese0.000343540See
USAUSA NMDP Japanese0.000224582See
USAUSA NMDP Chinese0.000299672See
KORSouth Korea pop 100.00024128See
CHNChina Jiangsu Han0.00023238See
DEUGermany pop 80.000239689See
DEUGermany DKMS - Croatia minority0.00022057See
USAUSA Asian pop 20.00031772See
ISRIsrael USA Jews0.00026058See
HKGHong Kong Chinese BMDR0.00017595See
HKGHong Kong Chinese cord blood registry0.00013892See
ISRIsrael Arab pop 20.000112301See
ISRIsrael Ashkenazi Jews pop 30.00014625See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
DEUGermany pop 60.00018862See
DEUGermany DKMS - Turkey minority0.00014856See
POLPoland DKMS0.000120653See
SAUSaudi Arabia pop 6 (G)0.000128927See
ISRIsrael Poland Jews0.000013871See
ISRIsrael USSR Jews0.000045681See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
NLDNetherlands Leiden0.00001305See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
ITAItaly pop 50.0000975See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
USAUSA Caucasian pop 40.00001070See
JPNJapan pop 110.00.000062See
INDIndia Northeast Lachung0.000058See
INDIndia Northeast Mech0.000063See
INDIndia Northeast Rajbanshi0.000098See
NIRIreland Northern0.00.00001000See
ESPSpain Murcia0.0000173See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
MKDMacedonia pop 10.0000158See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
CZECzech Republic0.0000106See
MNGMongolia Oold0.0000104See
MNGMongolia Tsaatan0.0000144See
CHNChina Hong Kong and Singapore0.0000135See
USAUSA African American Bethesda0.00.0000187See
FRAFrance West0.00.0000100See
USAUSA Caucasian Houston0.00.0000194See
USAUSA Caucasian Pittsburgh0.00.0000177See
CAFCentral African Republic Aka Pygmy0.00.000093See
CODCongo Kinshasa Bantu0.00.000090See
RUSRussia Siberia Sulamai Ket0.000022See
RUSRussia Siberia Polygus Evenk0.000035See
MNGMongolia Hoton0.000085See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
CHNChina Harbin Manchu0.0000172See
CHNChina Harbin Korean0.0000201See
ENGEngland pop 60.00.0000177See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
IDNIndonesia Singaporean0.000050See
KORSouth Korea pop 30.0000485See
USAUSA Philadelphia Caucasian0.00.0000141See
RUSRussia Tuva pop30.000044See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Irkutsk Tofalar0.000043See
RUSRussia Siberia Kushun Buryat0.000025See
RUSRussia Siberia Khanty Mansi0.000068See
CHNChina Urumqi Han0.000059See
CHNChina Urumqi Kazak0.000042See
CHNChina Urumqi Uyghur0.00.000057See
ISRIsrael Moroccan Jews0.0000113See
ISRIsrael Ashkenazi Jews pop 20.0000132See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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