To summarise Cytokine data stored in the Allele Frequency Net Database we have classified alleles grouped by
Gene and most frequently are listed on the right side.
Cytokines
Gene
Cytokines reported in Website
Total Entries
AIF-1/
3
6
bFGF/
3
3
EGF/
3
6
GM-CSF/
6
6
IFNgamma/
6
246
IGF-1/
6
6
IL-10/
9
834
IL-12/
3
132
IL-12p40/
3
3
IL-13/
9
12
IL-15/
6
6
IL-18/
12
27
IL-1alpha/
4
153
IL-1beta/
11
298
IL1R/
3
126
IL1RA/
3
129
IL-2/
6
301
IL-4/
15
432
IL-4R alpha/
3
144
IL-4R/
3
6
IL-6/
6
417
IL-8/
3
3
NGF/
3
3
PDGF B/
3
3
RANTES/
3
3
TGFbeta1/
12
450
TNFalpha/
15
540
TNFbeta/
3
42
VEGF/
15
39
Total
180
4,376
Top Cytokine Entries
Cytokine
Total Entries
TNFalpha/ - 308 AA
114
TNFalpha/ - 308 GG
114
TNFalpha/ - 308 AG
114
IL-10/ - 1082 AA
99
IL-10/ - 1082 AG
99
IL-10/ - 1082 GG
99
IL-6/ - 174 CC
98
IL-6/ - 174 CG
98
IL-6/ - 174 GG
98
IL-10/ - 592 AC
90
IL-10/ - 592 AA
90
IL-10/ - 592 CC
90
IL-10/ - 819 CC
89
IL-10/ - 819 CT
89
IL-10/ - 819 TT
89
TGFbeta1/codon 25 CG
74
TGFbeta1/codon 25 CC
74
TGFbeta1/codon 25 GG
74
TGFbeta1/codon 10 CT
68
TGFbeta1/codon 10 TT
68
TGFbeta1/codon 10 CC
68
IL-2/ - 330 TT
57
IL-4/ - 590 CC
57
IL-4/ - 590 CT
57
IL-4/ - 590 TT
57
IL-2/ - 330 GT
56
TNFalpha/ - 238 AG
56
IL-2/ - 330 GG
56
TNFalpha/ - 238 AA
56
TNFalpha/ - 238 GG
56
Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.