Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 227 time(s) and present in 190 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ZAFSouth Africa Natal Zulu22.00.1100100See
CMRCameroon Yaounde0.104092See
CMRCameroon Baka Pygmy0.100010See
ZWEZimbabwe Harare Shona0.0960230See
CMRCameroon Bamileke0.084077See
PRTAzores Central Islands0.080059See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,15.00.07834335See
CMRCameroon Sawa0.077013See
PRTPortugal South0.071049See
PRTPortugal Center0.070050See
MARMorocco Settat Chaouya13.60.068098See
MARMorocco Atlantic Coast Chaouya0.068098See
PRTAzores Oriental Islands0.064043See
CUBCuba Caucasian12.90.064070See
CMRCameroon Beti0.0630174See
DEUGermany DKMS - Spain minority0.06211107See
USAUSA NMDP Caribean Hispanic0.0607115374See
ZMBZambia Lusaka0.058044See
USAUSA San Antonio Caucasian0.0572222See
FRAFrance French Bone Marrow Donor Registry0.056642623See
USAUSA NMDP Caribean Indian0.056014339See
USAUSA African American Bethesda9.90.0540187See
KENKenya Luo0.0530265See
CHESwitzerland Geneva pop 20.05241267See
CHLChile Santiago Mixed10.00.051370See
FRAFrance Southeast10.00.0510130See
UGAUganda Kampala pop 20.0510175See
KENKenya, Nyanza Province, Luo tribe9.00.0500100See
NIRIreland Northern9.50.04901000See
USAUSA Hispanic0.0490234See
COLColombia North Wiwa El Encanto0.048152See
CPVCape Verde Southeastern Islands0.048062See
CUBCuba Mixed Race9.50.048042See
KENKenya Nandi0.0480240See
USAUSA San Francisco Caucasian0.0480220See
NLDNetherlands UMCU9.40.046964See
COLColombia Bogotá Cord Blood9.00.04551463See
USAUSA NMDP Hispanic South or Central American0.0441146714See
USAUSA San Diego8.40.0440496See
PAKPakistan Karachi Parsi0.044091See
USAUSA Caucasian pop 20.0430265See
COLColombia North Chimila Amerindians0.042547See
GNBGuinea Bissau Balanta0.042048See
USAUSA Hispanic pop 20.04171999See
TZATanzania Maasai8.10.0403336See
ECUEcuador Amerindians0.039763See
PRTPortugal Azores Terceira Island7.90.0395130See
USAUSA Caucasian pop 40.03931070See
USAUSA NMDP Mexican or Chicano0.0390261235See
PRTAzores Terceira Island0.0390130See
MEXMexico Mexico City Mestizo population0.0385143See
DEUGermany DKMS - Portugal minority0.03831176See
SENSenegal Niokholo Mandenka0.0380165See
CHESwitzerland Luzern0.03781553See
USAUSA African American pop 40.03642411See
USAUSA African American0.0360252See
USAUSA NMDP European Caucasian0.03531242890See
DEUGermany DKMS - France minority0.03521406See
DEUGermany DKMS - United Kingdom minority0.03521043See
PRTPortugal North0.033046See
MLIMali Bandiagara0.0330138See
USAUSA Caucasian Bethesda5.90.0330307See
IRLIreland South6.40.0320250See
USAUSA NMDP African American pop 20.0318416581See
CHESwitzerland Graubunden0.0317759See
USAUSA NMDP American Indian South or Central America0.03105926See
UGAUganda Kampala0.0310161See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
ISRIsrael Tunisia Jews0.03089070See
USAUSA NMDP African0.030328557See
USAUSA African American pop 20.0300149See
USAUSA South Texas Hispanic0.0300194See
STPSao Tome Island Forro0.030066See
BRABrazil Mixed0.0300108See
AUSAustralia New South Wales Caucasian0.0300134See
USAUSA NMDP Caribean Black0.029333328See
ZAFSouth Africa Worcester6.00.0280159See
USAUSA NMDP North American Amerindian0.027435791See
USAUSA North American Native0.0270187See
INDIndia Delhi pop 25.60.027090See
BRABrazil Belo Horizonte Caucasian5.30.026095See
MEXMexico Mexico City Mestizo pop 20.0256234See
NLDNetherlands Leiden0.02501305See
ARMArmenia combined Regions0.0250100See
DEUGermany DKMS - Austria minority0.02471698See
DEUGermany DKMS - Netherlands minority0.02481374See
CHESwitzerland Aargau-Solothurn0.02431838See
CHESwitzerland Lugano0.02401169See
NICNicaragua Managua4.50.0240339See
MEXMexico Mestizo4.90.024041See
DEUGermany pop 80.023939689See
CHESwitzerland Zurich0.02374875See
DEUGermany pop 60.02358862See
DEUGermany DKMS - German donors0.02303456066See
CHESwitzerland Bern0.02303545See
USAUSA Philadelphia Caucasian4.40.0220141See
DEUGermany DKMS - Italy minority0.02111159See
ITAItaly pop 50.0210975See
USAUSA Eastern European0.0210558See
USAUSA NMDP Alaska Native or Aleut0.02001376See
INDIndia West Coast Parsi0.020050See
ISRIsrael Arab Druze0.0200101See
CZECzech Republic NMDR0.01965099See
USAUSA NMDP Middle Eastern or North Coast of Africa0.019370890See
ITAItaly North pop 33.80.019097See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks3.60.0180112See
CHESwitzerland St Gallen0.01802113See
SDNSudan Mixed3.50.0180200See
USAUSA Caucasian pop 30.017088See
DEUGermany DKMS - Romania minority0.01701234See
GNBGuinea Bissau Fula0.016031See
CPVCape Verde Northwestern Islands0.016062See
STPSao Tome Island Angolar0.016032See
CHESwitzerland Basel0.01591888See
MEXMexico Sonora Seri0.015034See
GNBGuinea Bissau0.015065See
POLPoland DKMS0.014220653See
CZECzech Republic0.0140106See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0130146See
ISRIsrael Ashkenazi Jews pop 30.01284625See
MEXMexico Chiapas Lacandon Mayans0.0115218See
ISRIsrael Libya Jews0.01123739See
USAUSA NMDP Hawaiian or other Pacific Islander0.010711499See
ISRIsrael Poland Jews0.009813871See
AREUnited Arab Emirates Abu Dhabi0.009652See
DEUGermany DKMS - Greece minority0.00951894See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00921028See
HRVCroatia pop 40.00914000See
DEUGermany DKMS - Croatia minority0.00882057See
SWESweden Southern Sami0.0080130See
DEUGermany DKMS - Turkey minority0.00694856See
ISRIsrael Arab pop 20.006712301See
ISRIsrael Morocco Jews0.006536718See
ISRIsrael USA Jews0.00616058See
ISRIsrael YemenJews0.006015542See
USAUSA Arizona Pima0.0060100See
RUSRussia Karelia0.00561075See
ISRIsrael Argentina Jews0.00554307See
USAUSA NMDP Vietnamese0.005043540See
SGPSingapore SGVP Chinese CHS0.005096See
MEXMexico Mixtec0.005097See
MEXMexico Guadalajara Mestizo pop 20.0050103See
MEXMexico Oaxaca Jamiltepec Mixtec0.005096See
GEOGeorgia Tibilisi0.0050109See
RUSRussia Bering Island Aleuts0.0048104See
ISRIsrael USSR Jews0.004345681See
CHESwitzerland Sion0.0041832See
SWESweden Northern Sami0.0040154See
USAUSA Asian0.0040358See
MNGMongolia Buryat0.0040141See
CHNChina Beijing Shijiazhuang Tianjian Han0.0030618See
USAUSA NMDP Filipino0.002950614See
ISRIsrael Druze0.00235914See
USAUSA NMDP Southeast Asian0.002227978See
GRCGreece pop 60.0021242See
CHNChina Jiangsu Han0.00203238See
USAUSA Alaska Yupik0.0020252See
USAUSA NMDP Japanese0.001824582See
CHNChina Jiangsu Province Han0.0018334See
ISRIsrael Kavkazi Jews0.00182840See
USAUSA Asian pop 20.00141772See
DEUGermany DKMS - China minority0.00141282See
USAUSA NMDP South Asian Indian0.0013185391See
USAUSA NMDP Chinese0.001099672See
ISRIsrael Ethiopia Jews0.00095928See
CHNChina Hubei Han0.20.00093732See
HKGHong Kong Chinese cord blood registry0.00093892See
HKGHong Kong Chinese BMDR0.00097595See
USAUSA NMDP Korean0.000777584See
ISRIsrael Iraq Jews0.000413270See
INDIndia Tamil Nadu0.00042492See
ISRIsrael Georgia Jews0.00034471See
ISRIsrael Iran Jews0.00028153See
ISRIsrael Bukhara Jews0.00022317See
KORSouth Korea pop 100.00014128See
KORSouth Korea pop 30.0000485See
PHLPhilippines Ivatan0.00.000050See
MARMorocco Nador Metalsa pop 20.000073See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
SGPSingapore Chinese0.00.0000149See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
HKGHong Kong Chinese0.00.0000569See
GNBGuinea Bissau Papel0.000025See
GNBGuinea Bissau Bijago0.000023See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
AUSAustralia Yuendumu Aborigine0.0000191See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
SGPSingapore SGVP. Indian INS0.000086See
SGPSingapore SGVP Malay MAS0.000089See
CHESwitzerland Lausanne0.0000993See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional