Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 259 time(s) and present in 236 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael YemenJews0.157415542See
PRTPortugal North0.141046See
JPNJapan pop 50.1220117See
PRTPortugal South0.112049See
PRTPortugal Center0.110050See
CMRCameroon Beti0.1090174See
INDIndia New Delhi0.106071See
ZAFSouth Africa Natal Zulu20.00.1050100See
ITAItaly North pop 320.00.100097See
SGPSingapore SGVP. Indian INS0.100086See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,18.70.09984335See
ISRIsrael Tunisia Jews0.09919070See
ISRIsrael Bukhara Jews0.09882317See
ISRIsrael Libya Jews0.09723739See
USAUSA NMDP Caribean Indian0.095014339See
CMRCameroon Bakola Pygmy18.00.094450See
IDNIndonesia Java Western17.80.0930236See
USAUSA NMDP Caribean Hispanic0.0894115374See
ISRIsrael Morocco Jews0.088636718See
KORSouth Korea pop 100.08834128See
GHAGhana Ga-Adangbe16.80.0878131See
JPNJapan Central0.0870371See
KORSouth Korea pop 30.0850485See
USAUSA NMDP Korean0.085077584See
CMRCameroon Bamileke0.084077See
LKASri Lanka Colombo16.10.0830714See
DEUGermany DKMS - Portugal minority0.08251176See
FRAFrance French Bone Marrow Donor Registry0.080142623See
USAUSA San Antonio Caucasian0.0783222See
DEUGermany DKMS - Spain minority0.07731107See
PRTAzores Oriental Islands0.077043See
USAUSA NMDP South Asian Indian0.0740185391See
CAFCentral African Republic Mbenzele Pygmy14.00.072636See
PRTAzores Central Islands0.071059See
USAUSA African American Bethesda12.80.0690187See
CHESwitzerland Luzern0.06861553See
JPNJapan pop 160.067518604See
CHESwitzerland Lausanne0.0674993See
USAUSA Caucasian Bethesda11.60.0660307See
ESPSpain Andalusia Romani0.066099See
NIRIreland Northern12.40.06501000See
SCOScotland Orkney12.80.064099See
CUBCuba Caucasian12.90.064070See
SGPSingapore Riau Malay0.0640132See
USAUSA San Diego11.90.0640496See
CHNChina Han HIV negative0.063072See
CHNChina Henan HIV negative0.063016See
MYSMalaysia Peninsular Malay12.30.0626951See
ISRIsrael USA Jews0.06256058See
JPNJapan pop 30.06201018See
CHESwitzerland Aargau-Solothurn0.06111838See
USAUSA NMDP Southeast Asian0.060927978See
USAUSA Hispanic pop 20.06081999See
USAUSA NMDP Japanese0.060524582See
USAUSA San Francisco Caucasian0.0600220See
ISRIsrael Argentina Jews0.05814307See
ISRIsrael USSR Jews0.058145681See
ZWEZimbabwe Harare Shona0.0580230See
USAUSA NMDP Caribean Black0.057733328See
INDIndia Tamil Nadu0.05692492See
USAUSA Caucasian pop 40.05681070See
CHESwitzerland Geneva pop 20.05621267See
COLColombia Bogotá Cord Blood10.70.05601463See
USAUSA Hispanic0.0560234See
USAUSA NMDP Hispanic South or Central American0.0552146714See
ENGEngland North West11.10.0550298See
INDIndia Delhi pop 29.90.055090See
MYSMalaysia Kelantan10.70.054028See
USAUSA African American pop 40.05372411See
CHESwitzerland Sion0.0531832See
ZAFSouth Africa Worcester10.00.0530159See
CHNChina Uyghur HIV negative0.053019See
BRABrazil Belo Horizonte Caucasian9.50.053095See
DEUGermany DKMS - France minority0.05201406See
GEOGeorgia Tibilisi Kurd0.052031See
DEUGermany DKMS - United Kingdom minority0.05131043See
ZAFSouth Africa Natal Tamil0.051051See
CHESwitzerland Zurich0.05044875See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0500146See
CMRCameroon Baka Pygmy0.050010See
ISRIsrael Poland Jews0.049413871See
CZECzech Republic NMDR0.04915099See
DEUGermany DKMS - Austria minority0.04831698See
AREUnited Arab Emirates Abu Dhabi0.048152See
USAUSA European American pop 20.04801245See
CUBCuba Mixed Race9.50.048042See
CHESwitzerland Bern0.04763545See
UGAUganda Kampala0.0470161See
CHNChina Guangzhou Han0.0470106See
USAUSA African American pop 80.0470605See
USAUSA NMDP Mexican or Chicano0.0470261235See
ISRIsrael Ashkenazi Jews pop 30.04684625See
USAUSA NMDP European Caucasian0.04671242890See
CHESwitzerland Graubunden0.0463759See
USAUSA NMDP African American pop 20.0459416581See
MEXMexico Mexico City Mestizo population0.0455143See
CHNChina Shanxi HIV negative0.045022See
USAUSA Asian0.0450358See
IRLIreland South8.80.0440250See
USAUSA NMDP American Indian South or Central America0.04405926See
CHNChina Jiangsu Han0.04403238See
PRTAzores Terceira Island0.0430130See
USAUSA NMDP African0.042428557See
USAUSA Asian pop 20.04241772See
CZECzech Republic0.0420106See
SGPSingapore SGVP Malay MAS0.042089See
POLPoland DKMS0.041720653See
DEUGermany pop 80.041539689See
USAUSA Eastern European0.0410558See
ARGArgentina Rosario Toba8.10.041086See
DEUGermany pop 60.04108862See
NICNicaragua Managua8.10.0407339See
MYSMalaysia Peninsular Indian7.70.0406271See
DEUGermany DKMS - German donors0.04053456066See
INDIndia Khandesh Region Pawra0.040050See
ISRIsrael Iran Jews0.03928153See
NLDNetherlands UMCU7.80.039164See
USAUSA South Texas Hispanic0.0390194See
COLColombia North Wiwa El Encanto0.038552See
DEUGermany DKMS - Italy minority0.03841159See
VNMVietnam Hanoi Kinh pop 20.0380170See
CMRCameroon Sawa0.038013See
USAUSA NMDP North American Amerindian0.037835791See
USAUSA Philadelphia Caucasian7.40.0370141See
CHESwitzerland Basel0.03681888See
NLDNetherlands Leiden0.03601305See
BRABrazil Mixed0.0360108See
CHLChile Santiago Mixed7.00.035670See
CHNChina Jiangsu Province Han0.0353334See
PRTPortugal Azores Terceira Island7.00.0351130See
CHESwitzerland Lugano0.03461169See
DEUGermany DKMS - Netherlands minority0.03471374See
MYSMalaysia Champa6.90.034029See
AUSAustralia New South Wales Caucasian0.0340134See
USAUSA African American0.0340252See
RUSRussia Bering Island Aleuts0.0337104See
DEUGermany DKMS - Romania minority0.03321234See
ISRIsrael Georgia Jews0.03274471See
USAUSA North American Native0.0320187See
USAUSA NMDP Middle Eastern or North Coast of Africa0.030070890See
SGPSingapore Thai0.0300100See
MEXMexico Sonora Seri0.030034See
USAUSA Caucasian pop 20.0300265See
CHNChina Beijing0.030067See
DEUGermany DKMS - Croatia minority0.02972057See
CHNChina Sichuan HIV negative0.029034See
TZATanzania Maasai5.70.0284336See
USAUSA NMDP Hawaiian or other Pacific Islander0.028011499See
MEXMexico Mexico City Mestizo pop 20.0278234See
CHESwitzerland St Gallen0.02782113See
USAUSA NMDP Vietnamese0.027543540See
ITAItaly pop 50.0270975See
CHNChina Beijing Shijiazhuang Tianjian Han0.0260618See
HRVCroatia pop 40.02594000See
DEUGermany DKMS - Bosnia and Herzegovina minority0.02531028See
USAUSA NMDP Alaska Native or Aleut0.02501376See
KENKenya, Nyanza Province, Luo tribe5.00.0250100See
RUSRussia Tuva pop 20.0250169See
DEUGermany DKMS - Greece minority0.02461894See
SRBSerbia pop 24.90.0240102See
SWESweden Southern Sami0.0240130See
USAUSA Hawaii Okinawa0.0240106See
MEXMexico Mestizo4.90.024041See
CHLChile Mapuche0.023866See
DEUGermany DKMS - China minority0.02341282See
ZMBZambia Lusaka0.023044See
RUSRussia Karelia0.02291075See
TUNTunisia Gabes0.021095See
MYSMalaysia Jelebu Temuan0.021025See
ISRIsrael Kavkazi Jews0.02012840See
MYSMalaysia Patani4.00.020025See
SGPSingapore Javaneses0.020051See
ISRIsrael Arab Druze0.0200101See
DEUGermany DKMS - Turkey minority0.01954856See
MYSMalaysia Mandailing3.70.019027See
GEOGeorgia Svaneti Region Svan0.019080See
INDIndia Andhra Pradesh Golla0.0190111See
ISRIsrael Arab pop 20.018612301See
CHNChina Hubei Han3.50.01733732See
CHNChina Canton Han0.0170264See
KENKenya Luo0.0170265See
ISRIsrael Ethiopia Jews0.01635928See
CHNChina South Han0.0160284See
USAUSA NMDP Filipino0.015550614See
SDNSudan Mixed3.00.0150200See
STPSao Tome Island Forro0.015066See
MLIMali Bandiagara0.0150138See
GRCGreece pop 60.0142242See
HKGHong Kong Chinese cord blood registry0.01413892See
USAUSA NMDP Chinese0.014099672See
GEOGeorgia Tibilisi0.0140109See
CHNChina Marrow Donor Registry0.0130600See
GRCGreece pop 82.40.012183See
MEXMexico Chiapas Lacandon Mayans0.0115218See
HKGHong Kong Chinese BMDR0.01157595See
COLColombia North Chimila Amerindians0.010647See
ARMArmenia combined Regions0.0100100See
TWNTaiwan Siraya2.00.010051See
TWNTaiwan Hakka1.80.009055See
TWNTaiwan pop 20.0090364See
HKGHong Kong Chinese1.60.0080569See
KENKenya Nandi0.0080240See
MYSMalaysia Peninsular Chinese1.60.0077194See
AUSAustralia Groote Eylandt Aborigine0.007075See
ITAItaly North Pavia0.006081See
TWNTaiwan Tzu Chi Cord Blood Bank0.0060710See
UGAUganda Kampala pop 20.0060175See
TWNTaiwan Han Chinese0.0060504See
SGPSingapore Chinese Han0.006094See
USAUSA Arizona Pima0.0060100See
USAUSA South Dakota Lakota Sioux0.0050302See
TWNTaiwan pop 30.0050212See
CHNChina Guangzhou0.0050102See
SENSenegal Niokholo Mandenka0.0050165See
TWNTaiwan Minnan pop 11.00.0050102See
SGPSingapore SGVP Chinese CHS0.005096See
MEXMexico Oaxaca Jamiltepec Mixtec0.005096See
MEXMexico Mixtec0.005097See
TWNTaiwan Tzu Chi Morrow Donor Registry0.004146682See
SWESweden Northern Sami0.0040154See
ISRIsrael Druze0.00375914See
CHNChina Yunnan Hani0.0030150See
SGPSingapore Chinese0.70.0030149See
ISRIsrael Iraq Jews0.002913270See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
INDIndia Mumbai Maratha0.000091See
INDIndia West Coast Parsi0.000050See
INDIndia West Bhil0.000050See
AUSAustralia Yuendumu Aborigine0.0000191See
JPNJapan Hokkaido Ainu0.000050See
CHNChina North Han0.0000105See
MARMorocco Nador Metalsa pop 20.000073See
STPSao Tome Island Angolar0.000032See
CHNChina Tibet Region Tibetan0.0000158See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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