Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 239 time(s) and present in 189 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
TWNTaiwan Ami42.90.260098See
USAUSA Arizona Gila River Amerindian0.2180492See
TWNTaiwan Taroko34.50.191055See
TWNTaiwan Atayal33.00.1700106See
USAUSA Arizona Pima0.1690100See
USAUSA Alaska Yupik0.1470252See
NZLNew Zealand Maori with Full Ancestry23.90.141046See
NZLNew Zealand Maori with Admixed History21.90.1240105See
PERPeru Titikaka Lake Uro0.1240105See
PERPeru Titikaka Lake Uros0.1240105See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.1223233See
TWNTaiwan Puyuma24.00.120050See
ASMAmerican Samoa0.100051See
USAUSA New Mexico Canoncito Navajo0.098042See
NZLNew Zealand Polynesians with Full Ancestry14.30.095021See
MEXMexico Chihuahua Tarahumara0.091044See
TWNTaiwan Bunun17.80.0890101See
TWNTaiwan Tsou17.60.088051See
TWNTaiwan Paiwan15.70.088051See
TWNTaiwan Thao16.70.083030See
PHLPhilippines Ivatan16.00.080050See
NZLNew Zealand Polynesians with Admixed History11.10.074027See
MYSMalaysia Kedah Kensiu14.30.071021See
JPNJapan Hokkaido Ainu0.070050See
TWNTaiwan Rukai14.00.070050See
USAUSA NMDP Hawaiian or other Pacific Islander0.069411499See
MEXMexico Oaxaca Jamiltepec Mixtec0.063096See
CHNChina Han HIV negative0.063072See
CHNChina Henan HIV negative0.063016See
MEXMexico Mixtec0.062097See
CHNChina North Han0.0570105See
USAUSA NMDP Alaska Native or Aleut0.05701376See
ARGArgentina Gran Chaco Eastern Toba10.30.0560135See
TWNTaiwan Pazeh10.90.055055See
CHNChina Beijing0.053067See
CHNChina Uyghur HIV negative0.053019See
RUSRussia Bering Island Aleuts0.0529104See
TWNTaiwan Siraya9.80.049051See
CHNChina Inner Mongolia Region0.0490102See
RUSRussia Tuva pop 20.0470169See
MEXMexico Oaxaca Zapotec0.045090See
JPNJapan pop 50.0430117See
MEXMexico Mexico City Mestizo pop 20.0427234See
CHNChina Tibet Region Tibetan0.0410158See
MYSMalaysia Kedah Baling Kensiu0.040025See
TWNTaiwan Tao6.00.040050See
MEXMexico Mexico City Tlalpan7.90.0394330See
TWNTaiwan Saisiat7.80.039051See
MEXMexico Mestizo7.30.037041See
USAUSA NMDP Korean0.036777584See
CHNChina Qinghai Province Hui0.0360110See
ARGArgentina Gran Chaco Western Toba Pilaga7.10.036019See
KORSouth Korea pop 100.03564128See
KORSouth Korea pop 30.0340485See
MEXMexico Sonora Seri0.030034See
JPNJapan Central0.0300371See
MEXMexico Veracruz Xalapa6.00.029884See
JPNJapan pop 160.028818604See
USAUSA NMDP Japanese0.027124582See
JPNJapan pop 30.02701018See
USAUSA NMDP Filipino0.026650614See
CHNChina Guizhou Province Bouyei0.0260109See
USAUSA NMDP Mexican or Chicano0.0254261235See
CHNChina Guizhou Province Shui0.0250153See
USAUSA Asian0.0240358See
DEUGermany DKMS - China minority0.02341282See
CHNChina Shanxi HIV negative0.023022See
CHNChina Jiangsu Han0.02303238See
PNGPapua New Guinea Wanigela Keapara0.023066See
USAUSA South Dakota Lakota Sioux0.0220302See
INDIndia Delhi pop 24.40.022090See
USAUSA Hispanic pop 20.02151999See
USAUSA North American Native0.0210187See
CHNChina Canton Han0.0210264See
USAUSA Asian pop 20.02041772See
TWNTaiwan Minnan pop 13.90.0200102See
CHNChina Beijing Shijiazhuang Tianjian Han0.0200618See
MYSMalaysia Sarawak Bau Bidayuh0.020025See
NCLNew Caledonia0.019065See
MEXMexico Guadalajara Mestizo pop 20.0190103See
CHNChina Guangzhou Han0.0190106See
SDNSudan East Rashaida3.70.018627See
USAUSA NMDP North American Amerindian0.018235791See
PNGPapua New Guinea Madang0.018065See
CHNChina Guizhou Province Miao pop 20.018085See
GEOGeorgia Tibilisi Kurd0.017031See
SGPSingapore Chinese2.70.0170149See
SGPSingapore Chinese Han0.017094See
TWNTaiwan Tzu Chi Cord Blood Bank0.0170710See
CHNChina South Han0.0160284See
IRNIran Gorgan0.016064See
CHNChina Jiangsu Province Han0.0157334See
CHLChile Mapuche0.015466See
CHLChile Santiago Mixed3.00.015170See
COLColombia Bogotá Cord Blood2.90.01471463See
USAUSA NMDP Hispanic South or Central American0.0142146714See
TWNTaiwan pop 30.0140212See
TWNTaiwan Han Chinese0.0140504See
USAUSA Hawaii Okinawa0.0140106See
SDNSudan Central Shaigiya Mixed2.70.013536See
USAUSA NMDP Chinese0.013199672See
USAUSA Hispanic0.0130234See
PNGPapua New Guinea East New Britain Rabaul0.013060See
TWNTaiwan pop 20.0130364See
HKGHong Kong Chinese2.60.0130569See
CHNChina Yunnan Province Nu0.0130107See
BRABrazil Puyanawa2.70.0130150See
TWNTaiwan Tzu Chi Morrow Donor Registry0.012546682See
HKGHong Kong Chinese cord blood registry0.01233892See
CHNChina Marrow Donor Registry0.0120600See
USAUSA NMDP American Indian South or Central America0.01205926See
HKGHong Kong Chinese BMDR0.01167595See
COLColombia North Chimila Amerindians0.010647See
CHNChina Yunnan Province Han0.0100101See
INDIndia North pop 20.010072See
INDIndia Andhra Pradesh Golla0.0100111See
PAKPakistan Burusho0.010092See
USAUSA San Diego1.90.0100496See
MYSMalaysia Peninsular Chinese1.60.0077194See
CHNChina Yunnan Hani0.0070150See
SWESweden Northern Sami0.0070154See
ISRIsrael Argentina Jews0.00624307See
RUSRussia Karelia0.00611075See
THAThailand Northeast0.006066See
ESPSpain Majorca and Minorca0.006090See
USAUSA NMDP Vietnamese0.006043540See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
ISRIsrael Poland Jews0.005413871See
ISRIsrael USSR Jews0.005445681See
MYSMalaysia Peninsular Malay1.10.0053951See
PAKPakistan Mixed Sindhi0.0050101See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0050146See
CHNChina Guangxi Region Maonan0.0050108See
AUSAustralia Cape York Peninsula Aborigine0.0050103See
THAThailand Northeast pop 20.0050400See
SGPSingapore SGVP Chinese CHS0.005096See
ISRIsrael USA Jews0.00486058See
NICNicaragua Managua0.90.0045339See
DEUGermany DKMS - Turkey minority0.00454856See
ISRIsrael Ashkenazi Jews pop 30.00444625See
USAUSA NMDP Southeast Asian0.004427978See
USAUSA South Texas Hispanic0.0040194See
CHNChina Yunnan Province Wa0.0040119See
USAUSA NMDP South Asian Indian0.0037185391See
USAUSA Eastern European0.0030558See
VNMVietnam Hanoi Kinh pop 20.0030170See
IDNIndonesia Sundanese and Javanese0.0030201See
DEUGermany DKMS - Croatia minority0.00292057See
CHESwitzerland Basel0.00281888See
USAUSA NMDP Caribean Hispanic0.0021115374See
USAUSA NMDP Caribean Indian0.002014339See
ENGEngland North West0.30.0020298See
LKASri Lanka Colombo0.40.0020714See
MYSMalaysia Peninsular Indian0.40.0018271See
INDIndia Tamil Nadu0.00182492See
CHESwitzerland Sion0.0016832See
DEUGermany DKMS - Romania minority0.00161234See
POLPoland DKMS0.001620653See
HRVCroatia pop 40.00144000See
DEUGermany DKMS - Greece minority0.00131894See
CHESwitzerland Luzern0.00131553See
NIRIreland Northern0.20.00101000See
USAUSA European American pop 20.00101245See
USAUSA Caucasian pop 40.00091070See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000970890See
DEUGermany DKMS - Italy minority0.00091159See
USAUSA NMDP European Caucasian0.00071242890See
DEUGermany pop 80.000739689See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00074335See
CZECzech Republic NMDR0.00065099See
ISRIsrael Georgia Jews0.00064471See
DEUGermany pop 60.00068862See
USAUSA NMDP African American pop 20.0005416581See
ISRIsrael Tunisia Jews0.00049070See
USAUSA NMDP Caribean Black0.000433328See
DEUGermany DKMS - Portugal minority0.00041176See
DEUGermany DKMS - Spain minority0.00051107See
DEUGermany DKMS - France minority0.00041406See
USAUSA NMDP African0.000428557See
CHESwitzerland Bern0.00033545See
USAUSA African American pop 40.00022411See
ISRIsrael Libya Jews0.00013739See
ISRIsrael YemenJews0.000015542See
ISRIsrael Morocco Jews0.000036718See
ISRIsrael Bukhara Jews0.00002317See
ISRIsrael Kavkazi Jews0.00002840See
ISRIsrael Iran Jews0.00008153See
ITAItaly Sardinia pop30.0000100See
ITAItaly pop 50.0000975See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Oaxaca Mixtec0.0000103See
IDNIndonesia Java pop 20.000036See
NLDNetherlands Leiden0.00001305See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Zurich0.00004875See
CHNChina Yunnan Province Jinuo0.0000109See
CHNChina Guangzhou0.0000102See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Aargau-Solothurn0.00001838See
ARGArgentina Gran Chaco Mataco Wichi0.00.000049See
AUSAustralia Yuendumu Aborigine0.0000191See
AUSAustralia New South Wales Caucasian0.0000134See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
BRABrazil Belo Horizonte Caucasian0.00.000095See
FRAFrance Corsica Island0.0000100See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
USAUSA African American pop 80.0000605See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
USAUSA San Antonio Caucasian0.0000222See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
SGPSingapore SGVP. Indian INS0.000086See
SGPSingapore SGVP Malay MAS0.000089See
THAThailand pop 30.000049See
TWNTaiwan Hakka0.00.000055See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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