Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 271 time(s) and present in 224 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SENSenegal Dakar26.70.1440112See
TUNTunisia Jerba Berber0.082055See
GABGabon Haut-Ogooue Dienga0.0780167See
GNBGuinea Bissau0.077065See
GNQEquatorial Guinea Bioko Island Bubi0.0680100See
KENKenya, Nyanza Province, Luo tribe13.00.0650100See
MNGMongolia Ulaanbaatar Khalkha0.061041See
CODCongo Kinshasa Bantu10.00.056090See
CAFCentral African Republic Aka Pygmy10.70.054093See
MARMorocco Settat Chaouya0.051098See
COLColombia West Embera0.050020See
MARMorocco Atlantic Coast Chaouya0.050098See
RWARwanda Kigali Hutu and Tutsi0.0480281See
ZWEZimbabwe Harare Shona0.0460230See
USAUSA African American Bethesda7.00.0420187See
CPVCape Verde Southeastern Islands0.040062See
SDNSudan Mixed7.00.0400200See
USAUSA African American pop 30.0400564See
USAUSA African American pop 40.03912411See
USAUSA Colorado Univ Cord Blood Bank African American0.0390261See
USAUSA NMDP African American pop 20.0388416581See
USAUSA NMDP African0.036828557See
USAUSA NMDP Caribean Black0.036733328See
COLColombia San Basilio de Palenque0.036042See
USAUSA African American pop 70.0340193See
TUNTunisia pop 30.0340104See
ESPSpain Murcia0.0320173See
COLColombia Barranquilla0.0320188See
COLColombia Bogota and Medellin Mestizo0.031065See
PRTPortugal Azores Terceira Island6.10.0307130See
DZAAlgeria pop 26.00.0304106See
ARGArgentina Rio Negro Mapuche0.029034See
PRTAzores Terceira Island0.0270130See
COLColombia West Cauca0.025020See
BRABrazil Mixed0.0250108See
DZAAlgeria Oran0.0250100See
IRNIran Azeri0.0250100See
ZAFSouth Africa Worcester5.00.0250159See
STPSao Tome Island Forro0.023066See
USAUSA NMDP Caribean Indian0.023014339See
USAUSA NMDP Caribean Hispanic0.0228115374See
ARGArgentina Chubut Tehuelche0.022023See
PRTPortugal North0.022046See
ISRIsrael Ethiopian Jews0.0210122See
PRTPortugal Center0.020050See
PRTPortugal South0.020049See
ITAItaly Bergamo3.00.0200101See
ESPSpain Granada0.0200280See
TUNTunisia Matmata Berber0.019081See
SVNSlovenia pop 23.60.0181140See
ISRIsrael Ethiopia Jews0.01815928See
HRVCroatia Krk Island Vrbnik0.018028See
ESPSpain North Cantabria0.018083See
ESPSpain Barcelona3.40.0170941See
COLColombia West Waunana0.017030See
IRNIran pop 20.0170120See
JPNJapan pop 113.20.016162See
STPSao Tome Island Angolar0.016032See
TUNTunisia Gabes Arab0.016096See
CPVCape Verde Northwestern Islands0.016062See
ESPSpain Pas Valley0.016088See
CHLChile Santiago Mixed3.00.015170See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,3.00.01514335See
CUBCuba Mixed0.015078See
ESPSpain Andalusia0.015099See
IRNIran Yazd Zoroastrian0.015065See
RUSRussia Northwest Slavic0.0150200See
MARMorocco Nador Metalsa0.015099See
ITAItaly Central0.0150380See
BRABrazil North East Mixed0.0140205See
TURTurkey pop 10.0140250See
IRNIran Fars Parsi0.014073See
ENGEngland pop 62.80.0140177See
ESPSpain Tenerife Island0.014083See
USAUSA Southern California Mestizo2.70.013573See
USAUSA Hispanic pop 20.01301999See
INDIndia Northeast Shia0.0130190See
BRABrazil Puyanawa2.70.0130150See
NICNicaragua Managua2.40.0120339See
MEXMexico Nuevo Leon Mestizo2.50.012040See
FRAFrance Southeast2.30.0120130See
BRABrazil Southeast Mixed Race2.40.012042See
SAUSaudi Arabia pop 6 (G)0.011728927See
USAUSA NMDP Hispanic South or Central American0.0113146714See
CHESwitzerland Luzern0.01121553See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.01101058See
ISRIsrael Moroccan Jews0.0110113See
COLColombia North Chimila Amerindians0.010647See
TUNTunisia Gabes0.010595See
TUNTunisia pop 20.0100111See
USAUSA Caucasian Houston1.20.0100194See
FRAFrance West2.00.0100100See
CZECzech Republic0.0100106See
GRCGreece pop32.00.0100246See
SAUSaudi Arabia Guraiat and Hail1.90.0100213See
USAUSA NMDP Mexican or Chicano0.0099261235See
AREUnited Arab Emirates Abu Dhabi0.009652See
CHESwitzerland Graubunden0.0095759See
COLColombia Bogotá Cord Blood1.80.00921463See
DEUGermany DKMS - Spain minority0.00931107See
USAUSA Mexican American Mestizo pop 30.0090116See
ISRIsrael Arab0.0090109See
PRTAzores Central Islands0.009059See
USAUSA Caucasian Pittsburgh1.80.0090177See
MEXMexico Mexico City Mestizo pop 20.0085234See
CHESwitzerland Basel0.00831888See
CHESwitzerland Lugano0.00801169See
MEXMexico Mexico City Mestizo pop 30.0080256See
ECUEcuador Cayapa0.0080183See
BRABrazil Paraná Caucasian1.60.0078641See
DEUGermany DKMS - Portugal minority0.00771176See
CHESwitzerland St Gallen0.00712113See
USAUSA NMDP American Indian South or Central America0.00705926See
BRABrazil Mato Grosso do Sul0.0070203See
USAUSA Eastern European0.0070558See
USAUSA Philadelphia Caucasian1.40.0070141See
INDIndia Northeast Mathur0.0070155See
ARGArgentina Buenos Aires1.40.0070466See
USAUSA Caucasian Bethesda1.40.0070307See
CHESwitzerland Aargau-Solothurn0.00661838See
ITAItaly pop 50.0060975See
MEXMexico Veracruz Xalapa1.20.006084See
COKCook Islands Rarotonga0.006078See
ETHEthiopia Oromo0.006083See
GEOGeorgia Svaneti Region Svan0.006080See
LBNLebanon Yuhmur0.006082See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
CHESwitzerland Zurich0.00554875See
BRABrazil Southeast Caucasian1.00.0050103See
ESPSpain North Cabuerniga0.005095See
ITAItaly Rome1.00.0050100See
POLPoland Wielkopolska Region0.005099See
MEXMexico Guanajuato and Jalisco Mestizo1.00.0050101See
IRNIran Kurd0.0050100See
INDIndia Uttar Pradesh0.0050202See
FRAFrance Rennes0.0050200See
CZECzech Republic pop 21.00.005099See
GRCGreece pop 40.005098See
INDIndia Northeast Vaish0.0050198See
USAUSA Philippines0.0050105See
FRAFrance Rennes pop 30.0050200See
HRVCroatia Krk Island0.0050212See
ARMArmenia combined Regions0.0050100See
CHLChile Santiago0.0049920See
RUSRussia Bering Island Aleuts0.0048104See
CHESwitzerland Sion0.0046832See
MEXMexico Mexico City Tlalpan0.90.0045330See
USAUSA San Antonio Caucasian0.0045222See
CHESwitzerland Lausanne0.0044993See
USAUSA NMDP North American Amerindian0.004435791See
GRCGreece pop 60.0041242See
SWESweden Southern Sami0.0040130See
USAUSA San Diego0.80.0040496See
CHNChina Wuhan0.80.0040121See
GRCGreece Crete0.0040135See
ISRIsrael Ashkenazi Jews pop 20.0040132See
USAUSA Caucasian pop 40.00391070See
DEUGermany DKMS - France minority0.00391406See
PRTMadeira pop 20.0030173See
NZLNew Zealand Maori0.0030200See
GAZGaza Palestinians0.0030165See
RUSRussia Tuva0.0030190See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00303830See
ENGEngland Bedfordshire0.60.0030354See
INDIndia Northeast Rastogi0.0030196See
LBNLebanon pop 20.0030191See
INDIndia Northeast Sunni0.0030188See
MEXMexico Highlands Mestizos0.60.0030160See
DEUGermany DKMS - United Kingdom minority0.00301043See
DEUGermany pop 80.002939689See
USAUSA NMDP Middle Eastern or North Coast of Africa0.002970890See
USAUSA NMDP European Caucasian0.00281242890See
DEUGermany DKMS - Austria minority0.00271698See
CZECzech Republic NMDR0.00265099See
DEUGermany DKMS - Italy minority0.00261159See
USAUSA Caucasian0.50.002561655See
USAUSA South Texas Hispanic0.0020194See
IRLIreland South0.40.0020250See
DEUGermany DKMS - Romania minority0.00201234See
USAUSA San Francisco Caucasian0.0020220See
USAUSA NMDP Alaska Native or Aleut0.00201376See
USAUSA Caucasian pop 50.0020268See
DEUGermany DKMS - Croatia minority0.00192057See
HRVCroatia pop 40.00184000See
DEUGermany pop 60.00178862See
ISRIsrael Arab pop 20.001512301See
USAUSA NMDP Hawaiian or other Pacific Islander0.001411499See
ISRIsrael Morocco Jews0.001436718See
CHESwitzerland Bern0.00123545See
POLPoland DKMS0.001220653See
NLDNetherlands Leiden0.00101305See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
NIRIreland Northern0.20.00101000See
DEUGermany DKMS - Netherlands minority0.00071374See
ISRIsrael Argentina Jews0.00064307See
ISRIsrael Poland Jews0.000413871See
ISRIsrael Druze0.00035914See
ISRIsrael Tunisia Jews0.00039070See
ISRIsrael USSR Jews0.000345681See
USAUSA NMDP Filipino0.000350614See
USAUSA NMDP Southeast Asian0.000227978See
DEUGermany DKMS - Turkey minority0.00024856See
DEUGermany DKMS - Greece minority0.00031894See
ISRIsrael USA Jews0.00026058See
KORSouth Korea pop 100.00014128See
USAUSA NMDP Japanese0.000124582See
USAUSA NMDP Vietnamese0.000143540See
USAUSA NMDP South Asian Indian0.0001185391See
USAUSA NMDP Chinese0.000199672See
ISRIsrael Ashkenazi Jews pop 30.00014625See
ISRIsrael Iraq Jews0.000013270See
ISRIsrael YemenJews0.000015542See
USAUSA NMDP Korean0.000077584See
ZAFSouth Africa Caucasians0.0000102See
CHESwitzerland Geneva pop 20.00001267See
CZECzech Republic Romani0.00.000034See
ARGArgentina Salta Wichi0.000024See
PRYParaguay Lengua0.000017See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
BRABrazil South Caucasian0.000073See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
ETHEthiopia Amhara0.000098See
BRABrazil Guarani Nandeva0.000086See
KORSouth Korea pop 20.00.0000207See
USAUSA Alaska Yupik0.0000252See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
MKDMacedonia pop 10.0000158See
BRABrazil Kaingang0.0000235See
MNGMongolia Tarialan Khoton0.000085See
PRYParaguay Aché0.000087See
PERPeru Quechua0.000044See
BRABrazil East Amazon0.000041See
WSMWestern Samoa and Tokelau0.000051See
IDNIndonesia Java Yogyakarta Region0.000062See
ISRIsrael Libyan Jews0.0000119See
ISRIsrael Iranian Jews0.0000101See
PRTAzores Oriental Islands0.000043See
CHNChina Urumqi Han0.000059See
CHNChina Urumqi Kazak0.000042See
CHNChina Urumqi Uyghur0.00.000057See
LBNLebanon Kafar Zubian0.000094See
LBNLebanon Niha el Shouff0.000061See
KORSouth Korea pop 30.0000485See
BRABrazil Central Plateau Xavante0.000074See
ARGArgentina Gran Chaco Eastern Toba0.0000135See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
USAUSA Asian pop 20.00001772See
INDIndia Northeast Lachung0.000058See
INDIndia Northeast Mech0.000063See
INDIndia Northeast Rajbanshi0.000098See
INDIndia Northeast Kayastha0.0000190See
ISRIsrael Yemenite Jews0.000076See
SAUSaudi Arabia0.00.000018See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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