Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 284 time(s) and present in 252 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MLIMali Bandiagara0.2280138See
GNBGuinea Bissau Fula0.211031See
GNBGuinea Bissau Papel0.200025See
GNBGuinea Bissau Bijago0.196023See
CMRCameroon Yaounde0.187092See
SENSenegal Niokholo Mandenka0.1770165See
GHAGhana Ga-Adangbe29.80.1756131See
GNBGuinea Bissau Balanta0.166048See
GNBGuinea Bissau0.156065See
CMRCameroon Bamileke0.149077See
CPVCape Verde Southeastern Islands0.148062See
CMRCameroon Beti0.1350174See
ISRIsrael YemenJews0.135015542See
STPSao Tome Island Forro0.128066See
ZWEZimbabwe Harare Shona0.1270230See
USAUSA African American pop 20.1210149See
USAUSA African American0.1110252See
USAUSA NMDP African American pop 20.1099416581See
PRTPortugal North0.109046See
USAUSA African American pop 30.1080564See
USAUSA African American pop 40.10772411See
USAUSA NMDP Caribean Black0.106833328See
USAUSA NMDP African0.104728557See
ZAFSouth Africa Natal Zulu20.00.1000100See
CUBCuba Mixed Race16.70.095042See
STPSao Tome Island Angolar0.092032See
UGAUganda Kampala pop 20.0910175See
KENKenya Luo0.0890265See
ZAFSouth Africa Worcester16.00.0880159See
KENKenya, Nyanza Province, Luo tribe16.00.0850100See
USAUSA African American Bethesda16.80.0840187See
MARMorocco Nador Metalsa pop 20.082073See
ZMBZambia Lusaka0.081044See
CPVCape Verde Northwestern Islands0.081062See
CUBCuba Caucasian14.30.079070See
CHNChina Beijing0.075067See
MARMorocco Settat Chaouya14.80.074098See
MARMorocco Atlantic Coast Chaouya0.074098See
TUNTunisia Gabes0.073695See
KENKenya Nandi0.0710240See
PRTAzores Central Islands0.071059See
UGAUganda Kampala0.0680161See
GEOGeorgia Tibilisi Kurd0.067031See
BRABrazil Pernambuco Mixed0.0640101See
PRTPortugal South0.061049See
ITAItaly North pop 311.50.058097See
SDNSudan Mixed9.50.0580200See
USAUSA NMDP Caribean Indian0.058014339See
ISRIsrael Arab Druze0.0550101See
USAUSA NMDP Caribean Hispanic0.0540115374See
SAUSaudi Arabia Guraiat and Hail10.80.0540213See
BRABrazil Belo Horizonte Caucasian9.50.053095See
ARMArmenia combined Regions0.0500100See
ESPSpain Majorca and Minorca0.050090See
VENVenezuela Colonia Tovar0.046586See
ESPSpain Catalonia Girona0.046088See
CHESwitzerland Sion0.0452832See
ISRIsrael Georgia Jews0.04524471See
CHESwitzerland Lausanne0.0451993See
ISRIsrael Iraq Jews0.042813270See
VENVenezuela Caracas Mestizo0.040050See
USAUSA South Texas Hispanic0.0390194See
MEXMexico Mestizo7.30.037041See
DEUGermany DKMS - Spain minority0.03701107See
DEUGermany DKMS - Portugal minority0.03701176See
USAUSA Hispanic pop 20.03691999See
USAUSA NMDP Hispanic South or Central American0.0368146714See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,7.10.03604335See
NICNicaragua Managua7.20.0359339See
IRNIran Yazd0.035756See
MEXMexico Veracruz Xalapa7.10.035784See
MEXMexico Chihuahua Chihuahua City Pop 26.80.034188See
USAUSA Philadelphia Caucasian6.70.0330141See
COLColombia Bogotá Cord Blood6.40.03281463See
CHESwitzerland Zurich0.03244875See
DEUGermany DKMS - Italy minority0.03241159See
ISRIsrael Arab pop 20.032012301See
DEUGermany DKMS - Austria minority0.03151698See
TZATanzania Maasai6.30.0313336See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.30.031316See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
USAUSA Italy Ancestry0.0310273See
PRTAzores Terceira Island0.0310130See
PRTPortugal Azores Terceira Island6.10.0307130See
USAUSA NMDP Middle Eastern or North Coast of Africa0.029770890See
ISRIsrael Poland Jews0.029713871See
ISRIsrael Tunisia Jews0.02979070See
ISRIsrael Ethiopia Jews0.02965928See
CHESwitzerland Luzern0.02941553See
CZECzech Republic NMDR0.02945099See
DEUGermany DKMS - Turkey minority0.02944856See
CHESwitzerland Bern0.02923545See
RUSRussia Tuva pop 20.0290169See
ISRIsrael Morocco Jews0.028236718See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
MEXMexico Mexico City Tlalpan5.50.0273330See
FRAFrance French Bone Marrow Donor Registry0.027042623See
DEUGermany DKMS - Greece minority0.02691894See
USAUSA NMDP Mexican or Chicano0.0264261235See
CRICosta Rica Cabecar NA-DHS_9 (G)5.30.026319See
MYSMalaysia Pahang Semai5.30.026038See
CHESwitzerland Aargau-Solothurn0.02601838See
PRTAzores Oriental Islands0.026043See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0260146See
ISRIsrael USA Jews0.02546058See
ISRIsrael Ashkenazi Jews pop 30.02534625See
IRNIran Kurd pop 20.025060See
IRNIran Saqqez-Baneh Kurds0.025060See
GRCGreece pop 60.0248242See
HRVCroatia pop 40.02484000See
USAUSA NMDP American Indian South or Central America0.02405926See
ISRIsrael Libya Jews0.02393739See
ECUEcuador Amerindians0.023863See
BOLBolivia/Peru Quechua NA-DHS_12 (G)4.80.023821See
DEUGermany pop 80.023239689See
USAUSA San Francisco Caucasian0.0230220See
CHNChina Shanxi HIV negative0.023022See
IRNIran Gorgan0.023064See
USAUSA Caucasian pop 30.023088See
USAUSA Mexican American Mestizo0.0230553See
POLPoland DKMS0.022820653See
ISRIsrael USSR Jews0.022545681See
DEUGermany DKMS - France minority0.02241406See
ISRIsrael Argentina Jews0.02234307See
AREUnited Arab Emirates Pop 10.0220570See
DEUGermany DKMS - Bosnia and Herzegovina minority0.02211028See
ITAItaly pop 50.0220975See
DEUGermany pop 60.02158862See
COLColombia North Chimila Amerindians0.021247See
DEUGermany DKMS - German donors0.02123456066See
USAUSA San Diego3.90.0210496See
ISRIsrael Druze0.02065914See
DEUGermany DKMS - Croatia minority0.02042057See
FRAFrance Rennes pop 30.0200200See
ESPSpain Gipuzkoa Basque0.0200100See
BRABrazil Mixed0.0200108See
DEUGermany DKMS - Romania minority0.01991234See
USAUSA NMDP European Caucasian0.01971242890See
AREUnited Arab Emirates Abu Dhabi0.019252See
GEOGeorgia Tibilisi0.0190109See
AUSAustralia New South Wales Caucasian0.0190134See
CZECzech Republic0.0190106See
USAUSA Hispanic0.0190234See
USAUSA NMDP North American Amerindian0.018135791See
GRCGreece pop 83.60.018183See
ENGEngland North West3.70.0180298See
USAUSA Caucasian Bethesda3.60.0180307See
MEXMexico Mexico City Mestizo pop 20.0171234See
USAUSA Eastern European0.0170558See
ISRIsrael Iran Jews0.01668153See
CHESwitzerland Lugano0.01601169See
USAUSA North American Native0.0160187See
DEUGermany DKMS - United Kingdom minority0.01541043See
CHLChile Santiago Mixed3.00.015170See
INDIndia New Delhi0.015071See
CHNChina Inner Mongolia Region0.0150102See
PAKPakistan Mixed Pathan0.0150100See
ZAFSouth Africa Caucasians0.0150102See
CHESwitzerland Geneva pop 20.01431267See
NIRIreland Northern2.70.01401000See
MNGMongolia Buryat0.0140141See
JORJordan Amman0.0140146See
RUSRussia Karelia0.01401075See
CHESwitzerland St Gallen0.01352113See
DEUGermany DKMS - Netherlands minority0.01311374See
USAUSA Caucasian pop 40.01311070See
PAKPakistan Mixed Sindhi0.0130101See
USAUSA Caucasian pop 20.0130265See
NLDNetherlands Leiden0.01301305See
USAUSA NMDP Alaska Native or Aleut0.01201376See
SGPSingapore SGVP. Indian INS0.012086See
FRAFrance Southeast2.30.0120130See
ITAItaly North Pavia0.012081See
ISRIsrael Kavkazi Jews0.01202840See
IRNIran Baloch0.0110100See
ITAItaly Bergamo2.00.0110101See
INDIndia North UCBB2.20.01095849See
MEXMexico Mexico City Mestizo population0.0105143See
BRABrazil Puyanawa2.00.0100150See
PRTPortugal Center0.010050See
INDIndia North pop 20.010072See
FRAFrance Corsica Island0.0100100See
CHNChina Qinghai Province Hui0.0090110See
CHNChina Jiangsu Province Han0.0088334See
IRLIreland South1.60.0080250See
CHLChile Mapuche0.007766See
MEXMexico Tixcacaltuyub Maya0.007567See
INDIndia Central UCBB1.50.00744204See
LKASri Lanka Colombo1.40.0070714See
USAUSA NMDP South Asian Indian0.0066185391See
USAUSA NMDP Hawaiian or other Pacific Islander0.006311499See
USAUSA NMDP Southeast Asian0.006127978See
CHESwitzerland Basel0.00601888See
CHNChina Canton Han0.0060264See
ESPSpain Andalusia Romani0.006099See
USAUSA Asian0.0060358See
USAUSA San Antonio Caucasian0.0060222See
IRNIran Tabriz Azeris0.005297See
MYSMalaysia Peninsular Chinese1.00.0052194See
MEXMexico Oaxaca Jamiltepec Mixtec0.005096See
USAUSA Spain Ancestry0.0050279See
MEXMexico Mixtec0.005097See
CHNChina Guangzhou0.0050102See
CHNChina South Han0.0050284See
MEXMexico Guadalajara Mestizo pop 20.0050103See
INDIndia Delhi pop 21.10.005090See
INDIndia West UCBB1.00.00505829See
ISRIsrael Bukhara Jews0.00452317See
DEUGermany DKMS - China minority0.00451282See
CHNChina Southwest Dai0.0040124See
CHNChina Jiangsu Han0.00403238See
CHNChina Beijing Shijiazhuang Tianjian Han0.0040618See
GTMGuatemala Mayan0.0040132See
INDIndia South UCBB0.70.003511446See
INDIndia Tamil Nadu0.00342492See
INDIndia East UCBB0.70.00332403See
MYSMalaysia Peninsular Malay0.60.0032951See
CHESwitzerland Graubunden0.0032759See
USAUSA NMDP Filipino0.003150614See
CHNChina Tibet Region Tibetan0.0030158See
USAUSA Asian pop 20.00231772See
USAUSA NMDP Chinese0.002199672See
MYSMalaysia Peninsular Indian0.40.0018271See
INDIndia Northeast UCBB0.30.0017296See
HKGHong Kong Chinese cord blood registry0.00153892See
HKGHong Kong Chinese BMDR0.00137595See
USAUSA NMDP Japanese0.001124582See
TWNTaiwan pop 20.0010364See
CHNChina Hubei Han0.20.00093732See
USAUSA NMDP Vietnamese0.000743540See
KORSouth Korea pop 100.00044128See
USAUSA NMDP Korean0.000377584See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000346682See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
SGPSingapore SGVP Malay MAS0.000089See
SGPSingapore SGVP Chinese CHS0.000096See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
ITAItaly Sardinia pop30.0000100See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CHNChina North Han0.0000105See
KORSouth Korea pop 30.0000485See
USAUSA Alaska Yupik0.0000252See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
AUSAustralia Yuendumu Aborigine0.0000191See
HKGHong Kong Chinese0.00.0000569See
SGPSingapore Chinese0.00.0000149See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See

See also higher resolution data of this allele

Allele  Number of Populations 
 A*23:01:01 33 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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