Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 442 time(s) and present in 426 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ESPSpain Ibiza0.244088See
ESPSpain Arratia Valley Basque0.240083See
ESPSpain Pas Valley0.233088See
ESPSpain Gipuzkoa Basque0.2320100See
ESPSpain Catalonia Girona0.213088See
GBRUnited Kingdom Orkney0.203688See
IRLIreland South pop 20.182017624See
CUBCuba Mixed0.179078See
ESPSpain Murcia0.1790173See
ENGEngland Leeds32.00.17535024See
ESPSpain Majorca and Minorca0.174090See
ENGEngland Newcastle31.70.17352739See
ENGEngland Manchester31.60.17291640See
WALWales pop 231.50.172039979See
ENGEngland Sheffield31.40.17174755See
ENGEngland Liverpool31.30.17111343See
PRTPortugal Viana do Castelo0.1710706See
FRAFrance Rennes pop 30.1700200See
BIHBosnia and Herzegovina pop 232.50.1667120See
ENGEngland Lancaster30.50.1663545See
ESPSpain Andalusia0.165099See
JPNJapan Aichi30.40.163050See
FRAFrance Marseille31.40.16301000See
FRAFrance Grenoble, Nantes and Rennes0.16206094See
FRAFrance Rennes pop 430.80.16181000See
ESPSpain, Castilla y Leon, Northwest,30.30.16001743See
PRTPortugal Aveiro0.15805933See
FRAFrance Bordeaux29.00.1551990See
ESPSpain Majorca0.1540407See
PRTPortugal Braga0.15301971See
PRTPortugal Porto0.15207937See
PRTPortugal Coimbra0.15205057See
PRTPortugal Evora0.1510737See
USAUSA OPTN Caucasian0.15008525See
PRTPortugal North0.150046See
FRAFrance Lyon28.40.14954813See
BIHBosnia and Herzegovina0.1492134See
PRTPortugal Lisbon0.149017420See
GBRUnited Kingdom pop 20.1490101See
PRTPortugal South pop 20.14901021See
ISRIsrael Moroccan Jews0.1480113See
USAUSA Caucasian Bethesda27.10.1470307See
PRTPortugal Vila Real0.14601167See
PRTPortugal Viseu0.14602915See
ESPSpain Minorca0.145094See
FRAFrance Grenoble28.30.14481000See
PRTPortugal Santarem0.14403865See
PRTPortugal Setubal0.14405268See
MEXMexico Jalisco, Tonala0.142935See
ESPSpain Sevilla25.90.1421278See
GEOGeorgia Kurds0.142030See
FRAFrance Southeast26.20.1410130See
PRTPortugal North pop 20.14011801See
PRTPortugal Leiria0.14001847See
PRTPortugal Castelo Branco0.1390327See
PRTPortugal Beja0.1390699See
ESPSpain North Cantabria0.138083See
PRTPortugal Faro0.13701242See
TUNTunisia pop 30.1360104See
AUSAustralia West Caucasian25.30.1350891See
NORNorway pop 20.1350576See
PRTPortugal Bragança0.1350301See
PRTPortugal Portalegre0.13401254See
TURTurkey pop 20.1340228See
NORNorway ethnic Norwegians25.00.13364510See
ESPSpain North Cabuerniga0.132095See
ARGArgentina Corrientes25.20.1320155See
ENGEngland North West Mixed pop 224.80.1306379See
AUTAustria Cord Bloods0.12961368See
BRABrazil South Ribeirao Preto0.1290184See
ECUEcuador Amazonia Mixed Ancestry0.128239See
PRTPortugal Guarda0.1270797See
SWESweden pop 423.70.1268966See
RUSRussia Northwest pop 322.00.1250100See
GBRUnited Kingdom North0.1244330See
BRABrazil REDOME Santa Catarina0.1241106673See
CHLChile Santiago0.1239920See
BRABrazil Rio Grande do Sul Caucasoid0.12304428See
PRTMadeira pop 30.1230538See
PRTPortugal Center pop 20.1220562See
BRABrazil Parana Oriental24.20.121033See
KORSouth Korea pop 10.1200324See
MEXMexico Baja California Rural0.120050See
BRABrazil REDOME Acre0.1199859See
SWESweden Uppsala22.30.1185300See
CMRCameroon Ewondo0.118038See
BRABrazil Sao Paulo Mixed22.00.1170239See
BRABrazil Rio Grande do Sul Mixed0.1170324See
BRABrazil REDOME Rio Grande do Sul0.1164241329See
BRABrazil REDOME Minas Gerais0.1162211275See
RUSRussia South Ural Russian22.20.1160207See
BRABrazil REDOME Rio de Janeiro0.1152139322See
ARGArgentina Buenos Aires21.70.1150466See
MARMorocco Casablanca0.1140100See
BRABrazil REDOME Sergipe0.11377321See
BRABrazil REDOME Goias0.113688574See
BRABrazil Rio Grande do Norte Mestizo0.113012973See
BRABrazil Minas Gerais State Mixed21.40.11301000See
PRTAzores Terceira Island0.1130130See
POLPoland pop 321.90.11232907See
ARMArmenia Shirak0.112076See
JPNJapan pop 1121.00.111162See
ZAFSouth Africa Tswana22.00.111041See
BRABrazil REDOME Federal District0.110629549See
BRABrazil REDOME Rio Grande do Norte0.110346603See
PRTMadeira pop 20.1100173See
BRABrazil REDOME Ceara0.1091101217See
SVKSlovakia pop 20.10904234See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.109096See
BRABrazil REDOME Rondonia0.109054396See
GBRUnited Kingdom Central0.1090135See
BRABrazil REDOME Espirito Santo0.108188485See
BRABrazil Parana Caucasian21.70.10802775See
BRABrazil Paraná Caucasian20.60.1076641See
BRABrazil Curitiba-Parana Mixed0.1070264See
BRABrazil REDOME Parana0.1070341639See
COLColombia Barranquilla0.1065188See
GBRUnited Kingdom South West0.1061163See
BRABrazil Sao Paulo Bauru Mixed0.10603542See
BRABrazil REDOME Tocantins0.105520692See
BRABrazil REDOME Sao Paulo0.1054800809See
ARGArgentina Buenos Aires pop 219.50.10501216See
RUSRussia Tatars0.1042355See
MMRMyanmar Rakhine20.80.104248See
LKASri Lanka Colombo Sinhalese0.1040101See
ITAItaly pop 619.00.1033184See
BRABrazil REDOME Pernambuco0.103192332See
BRABrazil REDOME Mato Grosso0.103034649See
KURIraq Kurdistan Region20.60.1030209See
KORSouth Korea pop 80.10307096See
BRABrazil REDOME Alagoas0.102625349See
BRABrazil REDOME Piaui0.102646140See
BRABrazil REDOME Mato Grosso do Sul0.102595667See
MEXMexico Sonora Rural0.1015197See
BRABrazil REDOME Paraiba0.101043868See
BRABrazil Piaui Mixed0.101021943See
RUSRussia Moscow0.10102650See
BRABrazil REDOME Bahia0.100947399See
BRABrazil South East Cord Blood0.100811409See
MEXMexico Chihuahua Rural0.1004236See
MEXMexico Baja California, Tijuana0.100025See
CMRCameroon Bamileke 20.100035See
TTOTrinidad African0.100067See
CZECzech Republic Romani pop 219.60.097846See
CUBCuba Mixed pop 20.0970189See
SVNSlovenia pop 318.50.0970130See
GAZGaza Palestinians0.0960165See
BRABrazil Para State17.10.09605000See
MARMorocco pop 20.0960110See
BRABrazil REDOME Maranhao0.095910180See
MEXMexico Sinaloa Rural0.0956183See
ITAItaly Bergamo17.80.0950101See
ESPSpain North18.00.0944156See
BRABrazil Pernambuco Mixed0.0940101See
BRABrazil Parana Cafuzo18.80.0940319See
MNGMongolia Tarialan Khoton0.094085See
RUSRussia Moscow Pop 218.00.09382000See
ARMArmenia Ghegharkunik0.0930242See
ARMArmenia Lori0.0930102See
RUSRussia Transbaikal Territory Buryats18.00.0930150See
ESPSpain Majorcans Jews0.0930103See
RUSRussia Northwest pop 217.80.0930346See
MEXMexico Mestizo pop 40.0929269See
MEXMexico Jalisco Rural0.0922585See
USAUSA OPTN Hispanic0.09201580See
BGDBangladesh Dhaka Bangalee0.0920141See
DEUGermany Essen17.20.0920174See
ALBAlbanian Kosovo0.0917120See
SRBSerbia pop 317.20.09161992See
BRABrazil REDOME Para0.091672637See
INDIndia North pop 30.0910587See
BRABrazil Parana Mixed race18.30.0910186See
ITAItaly Lombardy16.90.0910674See
MEXMexico Guanajuato, Guanajuato city0.090922See
GBRUnited Kingdom East0.0901163See
USAUSA African American Bethesda17.00.0900187See
ITAItaly North Pavia pop 217.10.09002416See
MEXMexico Guanajuato, Leon0.089778See
MEXMexico Coahuila, Saltillo0.089072See
JPNJapan Tohoku Region0.0890322See
RUSRussia Samara Region0.08902500See
DZAAlgeria pop 217.00.0889106See
MKDMacedonia MBMDR - Macedonian17.10.08851283See
CHNChina Harbin Korean0.0880201See
BRABrazil REDOME Roraima0.08774140See
ITAItaly North Pavia pop 30.0875685See
MEXMexico Sinaloa, Culiacán0.0874103See
MEXMexico Durango Rural0.0872326See
MMRMyanmar Bamar17.40.087046See
ARGArgentina La Plata17.00.0870100See
BRABrazil REDOME Amazonas0.086824129See
MEXMexico Guerrero state0.0868144See
ARGArgentina Cuyo Region16.40.0860420See
MMRMyanmar Mon17.20.085964See
MEXMexico Zacatecas, Fresnillo0.0857103See
SRBSerbia Vojvodina16.50.0850400See
INDIndia Kerala Hindu Nair0.085041See
BRABrazil Belem Mixed17.00.0850100See
BRABrazil Rio Grande do Sul Black0.0840248See
ARMArmenia living in Lebanon0.0840368See
MEXMexico Quintana Roo, Cancun0.083348See
MEXMexico Coahuila Rural0.0826216See
ROMRomania pop 316.10.08231469See
JPNJapan Hyogo Osaka and Nagano0.0820195See
MEXMexico Nuevo Leon, Monterrey city0.0819226See
RUSRussia Northwest15.70.08181011See
MEXMexico Queretaro Rural0.081443See
MEXMexico Veracruz, Coatzacoalcos0.080455See
ROMRomania pop 20.08006936See
GRCGreece pop 70.079911250See
IRQIraq Erbil15.90.0794372See
TUNTunisia Ghannouch0.079082See
BRABrazil REDOME Amapa0.078917864See
MKDMacedonia MBMDR - Albanian13.30.0781128See
ARMArmenia living in Karabakh0.0780445See
MKDMacedonia pop 30.0780172See
ISRIsrael Jews pop 215.10.078023000See
JPNJapan Kyoto and Osaka0.0760165See
MEXMexico Sonora, Hermosillo0.075899See
ARMArmenia Yerevan0.0750445See
TURTurkey pop 50.0740142See
ENGEngland London Ashkenazi Jews0.0730500See
ARMArmenia Syunik0.0730117See
MEXMexico Zacatecas Rural0.0725266See
MEXMexico Coahuila, Torreon0.0725396See
MKDMacedonia MBMDR - Macedonian Muslims14.50.072476See
MEXMexico Nayarit, Tepic0.072297See
MKDMacedonia pop 40.0720216See
BRABrazil Para Cord Blood Unit13.70.0719841See
MEXMexico Jalisco, Guadalajara city0.07161189See
MEXMexico Chihuahua Chihuahua City0.0714119See
MEXMexico Durango, Durango city0.0710153See
ARMArmenia living in Iran0.071085See
MEXMexico Puebla Mestizo0.071099See
MEXMexico Sinaloa Mestizo0.071056See
HRVCroatia pop 314.20.0708120See
BRABrazil Parana Japanese14.00.0703192See
MEXMexico Nayarit Rural0.070364See
ITAItaly East Sicily12.00.070050See
VENVenezuela Caracas Mestizo0.070050See
MEXMexico Chihuahua, Ciudad Juarez0.0694106See
MEXMexico Colima Rural0.068243See
INDIndia North Gujarat13.30.0681338See
GHAGhana Accre Asutuare Akan0.0680429See
CZECzech Republic Kurd13.50.067674See
MEXMexico Guanajuato Rural0.0675162See
GRCGreece pop313.00.0672246See
ALBAlbania pop 213.40.0671432See
MEXMexico Morelos, Cuernavaca0.067182See
RUSRussia South Ural Tatar13.30.0670135See
MEXMexico Morelos Rural0.066730See
INDIndia sub-Himalayan West Bengal Kami13.30.0665158See
NORNorway Sami0.0660200See
USAUSA OPTN African American0.06601510See
BRABrazil Parana Afro Brazilian13.00.065077See
FRAFrance Corsica Island0.0650100See
MEXMexico Mexico City Center0.0649152See
MMRMyanmar Shan13.00.064854See
INDIndia Jalpaiguri Toto12.50.064540See
FRAFrance Reims0.0640102See
ARMArmenia living in USA0.0640233See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks11.60.0630112See
MEXMexico Sonora, Ciudad Obregón0.0629143See
MEXMexico Michoacan, Morelia0.0629150See
MEXMexico Jalisco, Zapopan0.0625168See
MEXMexico Veracruz, Cordoba0.062556See
MYSMalaysia pop 30.06201445See
TZATanzania Dodoma Kongwa0.0620212See
MEXMexico Mexico City Mestizo0.0620121See
CHNChina Shandong Province11.70.06107418See
CHNChina Harbin Manchu0.0610172See
ISRIsrael Ashkenazi Jews pop 20.0610132See
PERPeru Arequipa Mestizo12.20.0610168See
IRQIraq Arabs12.10.0604149See
MYSMalaysia Negeri Sembilan Minangkabau0.060034See
TTOTrinidad South Asian0.060087See
RUSRussia Arkhangelsk Pomor0.060063See
MEXMexico Baja California, La Paz0.060075See
MEXMexico Baja Californa, Mexicali0.0600100See
MEXMexico Mexico City Metropolitan Area Rural0.0592150See
RUSRussia North Ossetian10.20.0591127See
JPNJapan pop 20.0590916See
INDIndia Kerala Malabar Muslim0.059034See
MEXMexico Campeche, Campeche city0.058834See
PAKPakistan Kalash0.058069See
MEXMexico Aguascalientes state0.057995See
MEXMexico Colima, Colima city0.057461See
ECUEcuador Mixed Ancestry0.05711173See
GRCGreece North0.0570500See
ECUEcuador Coast Mixed Ancestry0.0567238See
CHNChina Shandong Province Linqu County10.90.0560139See
ITAItaly North Pavia0.056081See
ECUEcuador Andes Mixed Ancestry0.0558824See
MEXMexico Nuevo Leon Rural0.0557439See
PAKPakistan Karachi Parsi0.055091See
ITAItaly Rome11.00.0550100See
HRVCroatia pop 20.0540100See
MEXMexico Zacatecas, Zacatecas city0.053684See
MEXMexico Jalisco, Tlaquepaque0.051339See
MEXMexico San Luis Potosi, San Luis Potosi city0.050030See
USAUSA OPTN Asian0.0500261See
CHNChina Shaanxi Province Han0.050010000See
MEXMexico Chiapas Rural0.0496121See
RUSRussia Chuvash0.049082See
MNGMongolia Ulaanbaatar Khalkha0.049041See
MEXMexico Tabasco, Villahermosa0.048882See
MEXMexico Michoacan Rural0.0487348See
IRNIran pop 40.0480855See
COLColombia San Basilio de Palenque0.048042See
INDIndia Kerala Syrian Christian0.048031See
GRCGreece Crete0.0480135See
MNGMongolia Oold0.0480104See
JPNJapan Hyogo9.40.047032See
MEXMexico Mexico City Mestizo pop 30.0470256See
VENVenezuela Colonia Tovar0.046586See
PAKPakistan Burusho0.046092See
MEXMexico San Luis Potosi Rural0.046087See
PAKPakistan Mixed Pathan0.0450100See
THAThailand pop 40.045016807See
MEXMexico Mexico City West0.044833See
MEXMexico Veracruz, Poza Rica0.044445See
MEXMexico Queretaro, Queretaro city0.044445See
MEXMexico Oaxaca, Oaxaca city0.0430151See
TWNTaiwan Chinese immigrants from North China0.0430152See
ITAItaly South Campania Region8.40.04291089See
MEXMexico Campeche Rural0.042647See
SDNSudan Central Shaigiya Mixed8.30.042436See
MEXMexico Tabasco Rural0.0423142See
MEXMexico Veracruz, Orizaba0.041760See
IRNIran Royan Cord Blood Bank8.10.041015600See
MEXMexico Veracruz, Veracruz city0.0407171See
MEXMexico Veracruz Rural0.0407539See
MYSMalaysia Perak Rawa0.040023See
PAKPakistan Mixed Sindhi0.0400101See
MNGMongolia Khalkha0.0400200See
RUSRussia Murmansk Saomi Mixed0.040070See
RUSRussia Nenet Mixed0.039055See
MEXMexico Yucatan, Merida0.0385192See
MEXMexico Puebla Rural0.0384833See
CHNChina Jiangsu Province0.038020248See
RUSRussia South Ural Bashkir7.50.0380146See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.037094See
MEXMexico Hidalgo Rural0.037081See
MEXMexico Hidalgo, Pachuca0.036641See
MMRMyanmar Kayah7.30.036455See
BOLBolivia Quechua0.036269See
MEXMexico Puebla, Puebla city0.03511994See
MEXMexico Tapachula, Chiapas Mestizo Population6.90.035072See
MYSMalaysia pop 20.035062See
SAUSaudi Arabia pop 20.0350383See
ITAItaly Sardinia pop30.0350100See
MEXMexico Mexico City North0.0339751See
MEXMexico Jalisco, Tlajomulco0.033330See
GTMGuatemala Mayan0.0330132See
THAThailand Northeast pop 20.0330400See
CHNChina Yunnan Province Nu0.0320107See
BFABurkina Faso Rimaibe0.032047See
CHNChina Yunnan Province Han pop 20.0320129See
MEXMexico Oaxaca Rural0.0318485See
MEXMexico Tamaulipas Rural0.0317125See
MEXMexico Mexico City East0.031379See
IRNIran pop 10.031064See
THAThailand Northeast0.031066See
SDNSudan Khartoum0.030698See
MNGMongolia Khalkha pop 20.0300202See
VNMVietnam Hanoi0.030050See
MEXMexico Veracruz, Xalapa0.0294187See
SAUSaudi Arabia5.60.028418See
MNGMongolia Tsaatan0.0280144See
MEXMexico Tlaxcala Rural0.0253830See
VENVenezuela Zulia Maracaibo Mixed0.025020See
CHNChina Shanghai0.025026266See
INDIndia Kerala Adiya0.024021See
GTMGuatemala, Guatemala City Mixed Ancestry4.70.0236127See
AREUnited Arab Emirates pop 24.60.0230373See
CMRCameroon Podokwo0.023043See
CHNChina Guangdong Province4.50.0227403See
SAUSaudi Arabia pop 44.20.0211499See
MYSMalaysia Sarawak Bidayuh0.020050See
BFABurkina Faso Fulani0.020049See
MEXMexico Tlaxcala, Tlaxcala city0.0193181See
BFABurkina Faso Mossi0.019053See
PAKPakistan Brahui0.0190104See
ARGArgentina Chiriguano3.80.019054See
MEXMexico Chiapas, Tuxtla Gutierrez0.018952See
MEXMexico Yucatan Rural0.0187132See
MMRMyanmar Chin3.60.018255See
MYSMalaysia Sabah Kadazan0.018057See
TWNTaiwan Chinese immigrants from South China0.0150172See
MEXMexico Michoacan Tarasco3.00.0150130See
INDIndia Kerala Hindu Namboothiri0.013040See
SENSenegal Dakar2.70.0130112See
CHNChina Yunnan Province Naxi0.0120118See
MMRMyanmar Kayin2.30.011444See
COLColombia Wayu from Guajira Peninsula0.010448See
MEXMexico Quintana Roo Rural0.010050See
MEXMexico San Vicente Tancuayalab Teenek/Huastecos0.009453See
TWNTaiwan Chinese immigrants from Middle China0.0090211See
MEXMexico Huasteca Region Teenek0.009055See
RUSRussia Sakhalin Island Nivkhi0.009053See
MEXMexico Sinaloa Capomos Mayo Yoremes0.008360See
CHNChina Wuhan1.70.0080121See
MMRMyanmar Kachin1.60.007963See
MEXMexico Mayan Pop 30.007066See
CHNChina Yunnan Province Lisu0.0070111See
PERPeru Lamas City Lama0.006083See
TWNTaiwan Minnan pop 20.00507137See
TWNTaiwan Minnan and Hakka0.0050190See
TWNTaiwan Hakka pop 20.0030714See
RUSRussia Bashkortostan, Tatars0.50.0026192See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Mexico City South0.000052See
TWNTaiwan Aborigine0.0000111See
MEXMexico Nahuas0.000072See
PAKPakistan Baloch0.000066See
ARGArgentina Salta Wichi pop 20.00.000019See
CHNChina North Han0.0000105See
INDIndia Kerala Paniya0.000010See
INDIndia Kerala Malapandaram0.000010See
INDIndia Kerala Kurichiya0.000010See
INDIndia Kerala Kanikkar0.000022See
INDIndia Kerala Kattunaikka0.000017See
INDIndia Kerala Kuruma0.000015See
INDIndia Kerala Hindu Pulaya0.000016See
INDIndia Kerala Hindu Ezhava0.000024See
CMRCameroon Uldeme0.000035See

See also higher resolution data of this allele

Allele  Number of Populations 
 B*44:03:02 41 
 B*44:25 16 
 B*44:27:01 10 
 B*44:05 159 
 B*44:10 76 
 B*44:22 14 
 B*44:20 18 
 B*44:06 93 
 B*44:11 47 
 B*44:21 25 
 B*44:15 38 
 B*44:12 17 
 B*44:03:01 68 
 B*44:26 11 
 B*44:38 16 
 B*44:18 25 
 B*44:02 255 
 B*44:17 26 
 B*44:33 10 
 B*44:29 35 
 B*44:07 67 
 B*44:24 21 
 B*44:02:01:01 18 
 B*44:37 11 
 B*44:03 261 
 B*44:19N 10 
 B*44:32 11 
 B*44:13 17 
 B*44:08 61 
 B*44:27 16 
 B*44:35 17 
 B*44:36 10 
 B*44:05:01 21 
 B*44:16 15 
 B*44:28 18 
 B*44:23N 12 
 B*44:02:01 33 
 B*44:04 123 
 B*44:30 19 
 B*44:09 69 
 B*44:14 26 
 B*44:31 11 
 B*44:34 11 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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