Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.

   

DRB1*12:02

Allele reported 293 time(s) and present in 247 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
CHNChina Yunnan Bulang0.5560116See
IDNIndonesia Java0.534058See
IDNIndonesia Java Yogyakarta Region0.507062See
IDNIndonesia Java pop 20.431036See
BORBorneo Bandjarmasin0.381021See
KIRKiribati0.379062See
IDNIndonesia Sundanese and Javanese0.3680201See
IDNIndonesia Java Western59.70.3650236See
VNMVietnam Hanoi Kinh pop 20.3530170See
MYSMalaysia0.344074See
SGPSingapore Riau Malay0.3240132See
MYSMalaysia Kelantan53.60.321028See
CHNChina Yunnan Hani0.3200150See
MYSMalaysia Mandailing55.60.315027See
MYSMalaysia Sarawak Bidayuh0.310050See
VNMVietnam Hanoi Kinh0.3040103See
MYSMalaysia Pahang Semai50.00.289038See
NRUNauru0.284067See
USAUSA NMDP Vietnamese0.283843540See
MYSMalaysia Sarawak Bau Bidayuh0.260025See
IDNIndonesia Singaporean0.260050See
MYSMalaysia Champa37.90.241029See
MYSMalaysia Sarawak Iban0.235051See
SGPSingapore SGVP Malay MAS0.231089See
MYSMalaysia Patani36.00.220025See
CHNChina Yunnan Province Han0.2170101See
PHLPhilippines0.191034See
THAThailand Bangkok pop 30.1870187See
INDIndia Northeast UCBB30.40.1791296See
THAThailand Kamphaeng Phet0.175097See
CHNChina Guangxi Region Maonan0.1710108See
MYSMalaysia Peninsular Malay26.80.1572951See
IDNIndonesia Nusa Tenggara Islands0.154049See
THAThailand Northeast0.151066See
THAThailand0.1510142See
SGPSingapore SGVP Chinese CHS0.150096See
MYSMalaysia Jelebu Temuan0.146025See
MYSMalaysia Kedah Kensiu28.60.143021See
MYSMalaysia Perak Grik Jehai0.140025See
THAThailand Bangkok pop 20.140050See
HKGHong Kong Chinese BMDR0.13697595See
HKGHong Kong Chinese cord blood registry0.13663892See
CHNChina Yunnan Province Naxi0.1360118See
THAThailand Northeast pop 20.1340400See
CHNChina Canton Han0.1330264See
USAUSA NMDP Filipino0.131350614See
CHNChina Hong Kong and Singapore0.1260135See
IDNIndonesia Moluccan Islands0.125024See
TWNTaiwan Aborigine pop 20.125048See
USAUSA Philippines0.1240105See
USAUSA Colorado Univ Cord Blood Bank Asian0.1170100See
USAUSA NMDP Chinese0.115099672See
TWNTaiwan pop10.1130539See
TWNTaiwan Tzu Chi Morrow Donor Registry0.106646682See
VNMVietnam HoaBinh Muong0.102083See
TWNTaiwan Tzu Chi Cord Blood Bank0.1010710See
TWNTaiwan pop 20.0970364See
CHNChina Southwest Dai0.0970124See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0944233See
CHNChina Jiangsu Province Han0.0914334See
CHNChina Wuhan16.50.0910121See
CHNChina Harbin Manchu0.0900172See
CHNChina Yunnan Province Han pop 20.0890129See
CHNChina Marrow Donor Registry0.0890600See
TWNTaiwan Han Chinese0.0860504See
CHNChina Hubei Han16.80.08413732See
CHNChina Zhejiang Han pop 20.0816833See
USAUSA NMDP Hawaiian or other Pacific Islander0.080911499See
MYSMalaysia Kedah Baling Kensiu0.080025See
JPNJapan Hokkaido Ainu0.080050See
DEUGermany DKMS - China minority0.07881282See
USAUSA Asian pop 20.07411772See
CHNChina Jiangsu Han0.07353238See
THAThailand North Dai Lue0.068096See
USAUSA NMDP Southeast Asian0.066327978See
CHNChina pop111.70.0600103See
CHNChina Urumqi Han0.059059See
CHNChina Beijing Shijiazhuang Tianjian Han0.0590618See
CHNChina Xinjiang Province Uyghur0.054092See
CHNChina Harbin Korean0.0520201See
MYSMalaysia Peninsular Chinese8.80.0516194See
CHNChina Harbin Manchu pop 20.050050See
CHNChina, Xinjiang Uyghur Autonomous Region Han7.50.050070See
KORSouth Korea pop 110.0470149See
KORSouth Korea pop 29.20.0460207See
MNGMongolia Khalkha0.0450200See
INDIndia East UCBB8.50.04252403See
PNGPapua New Guinea Lowland0.039047See
PNGPapua New Guinea South Gidra0.0390192See
KORSouth Korea pop 47.60.0387211See
MNGMongolia Ulaanbaatar Khalkha0.037041See
RUSRussia Transbaikal Territory Buryats7.00.0370150See
INDIndia South UCBB7.10.035511446See
CHNChina Beijing and Xian0.0350171See
USAUSA NMDP Korean0.034577584See
LKASri Lanka Colombo6.60.0340714See
KORSouth Korea pop 100.03344128See
KORSouth Korea pop 30.0330485See
KORSouth Korea pop 60.0300800See
MNGMongolia Khalkha pop 20.0300202See
USAUSA NMDP South Asian Indian0.0299185391See
CHNChina, Xinjiang Uyghur Autonomous Region Hui5.90.029440See
INDIndia North5.80.029485See
INDIndia Northeast Kayastha0.0290190See
INDIndia Northeast Sunni0.0290188See
JPNJapan Kyoto and Osaka0.0270165See
JPNJapan pop 20.0270916See
MYSMalaysia Sabah Kadazan0.026057See
INDIndia Tamil Nadu0.02602492See
INDIndia Lucknow5.00.0250123See
KORSouth Korea pop 10.0250324See
ZAFSouth Africa Worcester5.00.0250159See
INDIndia West UCBB5.00.02485829See
INDIndia Northeast Rastogi0.0230196See
BRABrazil Puyanawa4.70.0230150See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur4.40.021771See
JPNJapan Hyogo Osaka and Nagano0.0210195See
MYSMalaysia Peninsular Indian4.10.0203271See
GRCCretan Islanders0.0202124See
INDIndia Northeast Vaish0.0200198See
INDIndia Uttar Pradesh0.0200202See
JPNJapan0.020050See
MEXMexico Mazahua0.020065See
MEXMexico Jaltepec Mazahuas0.020050See
RUSRussia Tuva0.0200190See
RUSRussia Siberia Kushun Buryat0.020025See
AREUnited Arab Emirates Abu Dhabi0.019252See
GRCGreece Crete0.0190135See
MNGMongolia Oold0.0190104See
INDIndia Central UCBB3.60.01824204See
JPNJapan pop 170.01823078See
JPNJapan pop 160.018118604See
PNGPapua New Guinea Trobriand Island0.018081See
CHNChina Urumqi Uyghur1.80.018057See
USAUSA NMDP Japanese0.017124582See
JPNJapan pop 30.01701018See
JPNJapan pop 113.20.016162See
JPNJapan Hyogo3.10.016032See
INDIndia Northeast Shia0.0160190See
STPSao Tome Island Angolar0.016032See
USAUSA San Diego2.80.0150496See
JPNJapan Central0.0150371See
CZECzech Republic Romani2.90.014634See
INDIndia Andhra Pradesh Golla0.0140111See
NIUNiue0.014070See
USAUSA Hawaii0.013039See
GNQEquatorial Guinea Bioko Island Bubi0.0130100See
JPNJapan pop 42.50.0130525See
JPNJapan South2.40.0120125See
CHNChina Urumqi Kazak0.012042See
MNGMongolia Hoton0.012085See
MNGMongolia Tarialan Khoton0.012085See
RUSRussia Tuva pop 20.0110169See
RUSRussia Tuva pop30.011044See
JPNJapan Aichi2.20.011050See
INDIndia Delhi0.0110112See
INDIndia Northeast Rajbanshi0.010098See
MYSMalaysia Sabah Dusun0.010048See
MTQMartinique0.0100100See
RUSRussia Siberia Chukchi0.008071See
CMRCameroon0.0080126See
INDIndia North UCBB1.50.00755849See
JPNJapan Hokkaido Wajin1.40.007071See
ZWEZimbabwe Harare Shona0.0070230See
USAUSA African American Bethesda1.40.0070187See
USAUSA Southern California Mestizo1.40.007073See
ECUEcuadorean Amerindians0.006775See
MEXMexico Mexico City Mestizo pop 20.0064234See
SAUSaudi Arabia pop 6 (G)0.006228927See
PNGPapua New Guinea Highland0.006094See
COKCook Islands Rarotonga0.006078See
AREUnited Arab Emirates Pop 10.0060570See
AUSAustralia Cape York Peninsula Aborigine0.0050103See
COLColombia Antioquia Paisa0.0050100See
DZAAlgeria pop 21.00.0050106See
ITAItaly Bergamo1.00.0050101See
ESPSpain Andalusia0.005099See
POLPoland Wielkopolska Region0.005099See
SVNSlovenia1.00.0050100See
USAUSA African American pop 70.0050193See
ZAFSouth Africa Caucasians0.0050102See
NLDNetherlands0.90.0045447See
ESPSpain Granada0.0040280See
MEXMexico Mexico City Mestizo population0.0035143See
PRTMadeira pop 20.0030173See
USAUSA NMDP Caribean Indian0.003014339See
USAUSA Caucasian Houston0.60.0030194See
USAUSA Caucasian Pittsburgh0.60.0030177See
USAUSA Caucasian Bethesda0.60.0030307See
INDIndia Northeast Mathur0.0030155See
USAUSA NMDP African American pop 20.0029416581See
USAUSA African American pop 40.00272411See
USAUSA NMDP Caribean Black0.002533328See
DEUGermany DKMS - France minority0.00251406See
COLColombia Barranquilla0.0025188See
USAUSA NMDP African0.002428557See
DEUGermany DKMS - Turkey minority0.00234856See
DEUGermany DKMS - Netherlands minority0.00221374See
GRCGreece pop 60.0021242See
BRABrazil Mato Grosso do Sul0.0020203See
USAUSA NMDP American Indian South or Central America0.00205926See
USAUSA Eastern European0.0020558See
RWARwanda Kigali Hutu and Tutsi0.0020281See
SAUSaudi Arabia Guraiat and Hail0.50.0020213See
TURTurkey pop 10.0020250See
USAUSA Colorado Univ Cord Blood Bank African American0.0020261See
USAUSA South Texas Hispanic0.0020194See
NLDNetherlands Leiden0.00201305See
USAUSA NMDP Mexican or Chicano0.0015261235See
RUSRussia Karelia0.00141075See
DEUGermany DKMS - United Kingdom minority0.00141043See
PANPanama0.0013462See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00101058See
ESPSpain Barcelona0.20.0010941See
USAUSA NMDP Hispanic South or Central American0.0008146714See
CHLChile Santiago0.0008920See
DEUGermany pop 80.000839689See
DEUGermany DKMS - Romania minority0.00081234See
BRABrazil Paraná Caucasian0.20.0008641See
DEUGermany DKMS - Greece minority0.00081894See
USAUSA Hispanic pop 20.00081999See
BELBelgium0.10.000731412See
USAUSA NMDP Caribean Hispanic0.0007115374See
ISRIsrael Poland Jews0.000613871See
CZECzech Republic NMDR0.00065099See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000670890See
ISRIsrael Ashkenazi Jews pop 30.00054625See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00054335See
ISRIsrael Argentina Jews0.00034307See
DEUGermany pop 60.00038862See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00033830See
USAUSA NMDP North American Amerindian0.000335791See
ISRIsrael USSR Jews0.000345681See
DEUGermany DKMS - German donors0.00023456066See
ISRIsrael Bukhara Jews0.00022317See
POLPoland DKMS0.000320653See
ISRIsrael Morocco Jews0.000236718See
ISRIsrael Kavkazi Jews0.00022840See
USAUSA NMDP European Caucasian0.00021242890See
ISRIsrael USA Jews0.00026058See
ISRIsrael Arab pop 20.000112301See
ISRIsrael YemenJews0.000115542See
ISRIsrael Iran Jews0.00018153See
ISRIsrael Tunisia Jews0.00019070See
ISRIsrael Iraq Jews0.000013270See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
INDIndia Northeast Lachung0.000058See
INDIndia Northeast Mech0.000063See
ISRIsrael Moroccan Jews0.0000113See
ISRIsrael Ashkenazi Jews pop 20.0000132See
ITAItaly pop 50.0000975See
JPNJapan Nagano0.00.000057See
JPNJapan pop 60.00.0000129See
FRAFrance Rennes pop 30.0000200See
DNKDenmark0.000055See
ESPSpain Murcia0.0000173See
CZECzech Republic0.0000106See
CZECzech Republic pop 20.00.000099See
CODCongo Kinshasa Bantu0.00.000090See
BRABrazil North East Mixed0.0000205See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BRABrazil Southeast Caucasian0.00.0000103See
BRABrazil Southeast Mixed Race0.00.000042See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CAFCentral African Republic Aka Pygmy0.00.000093See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
USAUSA Philadelphia Caucasian0.00.0000141See
RUSRussia Siberia Khanty Mansi0.000068See
RUSRussia Siberia Ulchi0.000073See
RUSRussia Siberia Negidal0.000035See
RUSRussia Siberia Khabarovsk Evenki0.000025See
SGPSingapore SGVP. Indian INS0.000086See
STPSao Tome Island Forro0.000066See
USAUSA Alaska Yupik0.0000252See
USAUSA San Antonio Caucasian0.0000222See
PRYParaguay Lengua0.000017See
PNGPapua New Guinea East New Britain Tolai0.000048See
PNGPapua New Guinea Highland pop20.000028See
PNGPapua New Guinea Lowland Wosera0.000079See
RUSRussia Siberia Eskimo0.000070See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Irkutsk Tofalar0.000043See
PNGPapua New Guinea Lowland Roro0.000026See
MEXMexico Highlands Mestizos0.00.0000160See
MEXMexico Nuevo Leon Mestizo0.00.000040See
MNGMongolia Tsaatan0.0000144See
WSMWestern Samoa and Tokelau0.000051See
WSMSamoa0.000029See
WSMSamoa West0.000022See

See also higher resolution data of this allele


Allele  Number of Populations 
 DRB1*12:02:01 75 
 DRB1*12:02:01:01 
 DRB1*12:02:02 26 
 DRB1*12:02:03 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

support@allelefrequencies.net


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