Mexico Tlaxcala Rural

Polymorphic Region:

HLA

Demographic Data
	Ethnic origin:	Mixed ancestry
	Geographic Region:	North America
	Latitude:	19º 14' N
	Longitude:	98º 20' W
	Family:	Not Known
	Urban/Rural:	Rural

Sample Data
	Sample Size:	830
	Test date:	2013
	Method(s):	SSP
	Source:	Other
	Loci typed:	A, B, DQB1, DRB1
	Additional notes:	Allele and haplotype frequencies were determined by Maximum Likelihood methods.

Bibliographic Reference
	Author(s):	R. Barquera, I. Hernandez, A. Bravo.
	Publication details:	Pavon Vargas MA, Barquera R, Lopez Gil C, et al. Genetic diversity of the HLA system in Tlaxcala, Mexico. Hum Immunol.Barquera R, Hernandez Zaragoza DI, Bravo Acevedo A, et al. The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure. Hum Immunol.
	Author's e-mail:	barquera@shh.mpg.de

Frequency Data

Allele Frequencies Haplotype Frequencies   Genotype Data (download csv) Ambiguity-resolved Genotype Data (download csv)

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Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
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