Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 229 time(s) and present in 179 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael Bukhara Jews0.12022317See
ISRIsrael Kavkazi Jews0.10252840See
USAUSA NMDP Vietnamese0.075343540See
ISRIsrael Iraq Jews0.069913270See
GEOGeorgia Tibilisi Kurd0.067031See
IRNIran Gorgan0.063064See
VNMVietnam Hanoi Kinh pop 20.0620170See
CAFCentral African Republic Mbenzele Pygmy11.00.056636See
ISRIsrael Druze0.05485914See
TUNTunisia Gabes0.047395See
CHLChile Mapuche0.046266See
MEXMexico Chihuahua Chihuahua City Pop 29.10.045588See
ISRIsrael Arab Druze0.0450101See
PAKPakistan Karachi Parsi0.044091See
ZAFSouth Africa Worcester8.00.0410159See
ISRIsrael Argentina Jews0.03804307See
ISRIsrael USA Jews0.03726058See
IRNIran Tabriz Azeris0.036197See
CHESwitzerland Lausanne0.0355993See
ISRIsrael Poland Jews0.035213871See
BRABrazil Puyanawa6.70.0330150See
ISRIsrael Ashkenazi Jews pop 30.03244625See
ISRIsrael USSR Jews0.032045681See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
IRNIran Baloch0.0280100See
MEXMexico Mexico City Tlalpan5.50.0273330See
TWNTaiwan Hakka5.50.027055See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0260146See
ISRIsrael YemenJews0.024215542See
ISRIsrael Arab pop 20.024012301See
ISRIsrael Ethiopia Jews0.02335928See
ISRIsrael Iran Jews0.02258153See
SAUSaudi Arabia Guraiat and Hail4.20.0210213See
INDIndia West Coast Parsi0.020050See
ISRIsrael Georgia Jews0.01924471See
GHAGhana Ga-Adangbe3.80.0191131See
INDIndia North pop 20.019072See
ISRIsrael Morocco Jews0.018736718See
SDNSudan East Rashaida3.70.018627See
MEXMexico Veracruz Xalapa3.60.017984See
JORJordan Amman0.0170146See
PAKPakistan Brahui0.0170104See
PAKPakistan Mixed Pathan0.0150100See
INDIndia New Delhi0.015071See
CHNChina Guangzhou0.0150102See
SGPSingapore Thai0.0150100See
ZAFSouth Africa Natal Zulu3.00.0150100See
USAUSA Asian pop 20.01441772See
UGAUganda Kampala pop 20.0140175See
DEUGermany DKMS - Turkey minority0.01334856See
USAUSA NMDP South Asian Indian0.0132185391See
USAUSA Asian0.0130358See
PRTAzores Oriental Islands0.013043See
CHNChina Canton Han0.0130264See
GEOGeorgia Svaneti Region Svan0.013080See
KENKenya Nandi0.0130240See
GRCGreece pop 60.0124242See
CHNChina Jiangsu Province Han0.0122334See
DEUGermany DKMS - China minority0.01211282See
HKGHong Kong Chinese2.50.0120569See
CHNChina South Han0.0120284See
CHESwitzerland Lugano0.01201169See
USAUSA NMDP Middle Eastern or North Coast of Africa0.011970890See
CHESwitzerland Zurich0.01184875See
USAUSA NMDP Southeast Asian0.011527978See
USAUSA Philadelphia Caucasian2.20.0110141See
KENKenya Luo0.0110265See
IDNIndonesia Java Western2.10.0110236See
INDIndia Delhi pop 22.20.011090See
NICNicaragua Managua2.10.0105339See
TZATanzania Maasai2.10.0104336See
HKGHong Kong Chinese BMDR0.01027595See
HKGHong Kong Chinese cord blood registry0.01023892See
CHNChina Inner Mongolia Region0.0100102See
ARMArmenia combined Regions0.0100100See
KENKenya, Nyanza Province, Luo tribe2.00.0100100See
KORSouth Korea pop 30.0100485See
PRTPortugal Center0.010050See
SGPSingapore Chinese2.00.0100149See
DEUGermany DKMS - Greece minority0.00981894See
AREUnited Arab Emirates Abu Dhabi0.009652See
IRNIran Yazd0.008956See
PAKPakistan Baloch0.008066See
CHNChina Marrow Donor Registry0.0080600See
STPSao Tome Island Forro0.008066See
ECUEcuador Amerindians0.007963See
INDIndia Tamil Nadu0.00782492See
KORSouth Korea pop 100.00784128See
DEUGermany DKMS - Italy minority0.00781159See
USAUSA NMDP Chinese0.007699672See
MYSMalaysia Peninsular Indian1.50.0074271See
LKASri Lanka Colombo1.40.0070714See
CUBCuba Caucasian1.40.007070See
CHNChina Beijing Shijiazhuang Tianjian Han0.0070618See
USAUSA Caucasian Bethesda1.40.0070307See
SWESweden Southern Sami0.0070130See
USAUSA NMDP Korean0.006477584See
UGAUganda Kampala0.0060161See
USAUSA San Antonio Caucasian0.0060222See
GRCGreece pop 81.20.006083See
IRLIreland South1.20.0060250See
DEUGermany DKMS - Romania minority0.00531234See
CHNChina Hubei Han1.00.00513732See
CHNChina Jiangsu Han0.00503238See
CZECzech Republic0.0050106See
ITAItaly pop 50.0050975See
PAKPakistan Burusho0.005092See
RUSRussia Bering Island Aleuts0.0048104See
CZECzech Republic NMDR0.00465099See
DEUGermany DKMS - Portugal minority0.00431176See
DEUGermany pop 80.004139689See
CHESwitzerland Sion0.0041832See
ZWEZimbabwe Harare Shona0.0040230See
PRTAzores Terceira Island0.0040130See
AUSAustralia New South Wales Caucasian0.0040134See
FRAFrance Southeast0.80.0040130See
MNGMongolia Buryat0.0040141See
MYSMalaysia Peninsular Malay0.70.0037951See
MEXMexico Mexico City Mestizo population0.0035143See
USAUSA Hispanic pop 20.00351999See
RUSRussia Karelia0.00331075See
DEUGermany DKMS - France minority0.00321406See
ENGEngland North West0.70.0030298See
TWNTaiwan Han Chinese0.0030504See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.60.00294335See
FRAFrance French Bone Marrow Donor Registry0.002842623See
USAUSA Caucasian pop 40.00281070See
USAUSA NMDP European Caucasian0.00271242890See
DEUGermany DKMS - Spain minority0.00271107See
CHESwitzerland Bern0.00273545See
MYSMalaysia Peninsular Chinese0.50.0026194See
ISRIsrael Tunisia Jews0.00259070See
POLPoland DKMS0.002420653See
DEUGermany DKMS - German donors0.00243456066See
USAUSA NMDP Hispanic South or Central American0.0021146714See
DEUGermany DKMS - Netherlands minority0.00221374See
NLDNetherlands Leiden0.00201305See
USAUSA Alaska Yupik0.0020252See
USAUSA Caucasian pop 20.0020265See
USAUSA Hispanic0.0020234See
USAUSA San Diego0.30.0020496See
USAUSA San Francisco Caucasian0.0020220See
USAUSA NMDP American Indian South or Central America0.00205926See
USAUSA NMDP Alaska Native or Aleut0.00201376See
USAUSA NMDP Mexican or Chicano0.0020261235See
USAUSA NMDP North American Amerindian0.001735791See
COLColombia Bogotá Cord Blood0.30.00171463See
USAUSA NMDP African0.001628557See
TWNTaiwan Tzu Chi Morrow Donor Registry0.001646682See
DEUGermany pop 60.00178862See
DEUGermany DKMS - Austria minority0.00151698See
USAUSA NMDP Hawaiian or other Pacific Islander0.001511499See
DEUGermany DKMS - United Kingdom minority0.00141043See
DEUGermany DKMS - Croatia minority0.00122057See
USAUSA African American pop 40.00102411See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
TWNTaiwan pop 20.0010364See
USAUSA NMDP Caribean Indian0.001014339See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00101028See
USAUSA NMDP Caribean Hispanic0.0009115374See
USAUSA NMDP Filipino0.000850614See
USAUSA NMDP Caribean Black0.000833328See
ISRIsrael Libya Jews0.00043739See
USAUSA NMDP Japanese0.000324582See
USAUSA NMDP African American pop 20.0003416581See
JPNJapan pop 160.000118604See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
MLIMali Bandiagara0.0000138See
PHLPhilippines Ivatan0.00.000050See
PAKPakistan Mixed Sindhi0.0000101See
PRTPortugal North0.000046See
NIRIreland Northern0.00.00001000See
PAKPakistan Kalash0.000069See
ITAItaly North pop 30.00.000097See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
CUBCuba Mixed Race0.00.000042See
BRABrazil Belo Horizonte Caucasian0.00.000095See
AUSAustralia Yuendumu Aborigine0.0000191See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Aargau-Solothurn0.00001838See
CHNChina Beijing0.000067See
CHNChina North Han0.0000105See
CHNChina Qinghai Province Hui0.0000110See
CHNChina Tibet Region Tibetan0.0000158See
USAUSA North American Native0.0000187See
USAUSA African American Bethesda0.00.0000187See
USAUSA African American0.0000252See
USAUSA South Texas Hispanic0.0000194See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
PRTPortugal South0.000049See
PRTAzores Central Islands0.000059See
STPSao Tome Island Angolar0.000032See
SDNSudan Mixed0.00.0000200See
ZMBZambia Lusaka0.000044See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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