Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 294 time(s) and present in 257 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
GRCGreece pop 816.90.102483See
AREUnited Arab Emirates Abu Dhabi0.096252See
PAKPakistan Brahui0.0920104See
ITAItaly Sardinia pop30.0870100See
TUNTunisia Ghannouch0.085082See
BFABurkina Faso Fulani0.082049See
PAKPakistan Karachi Parsi0.078091See
SDNSudan East Rashaida14.80.076927See
PAKPakistan Kalash0.075069See
SDNSudan Central Shaigiya Mixed13.90.072136See
FRAFrance Southeast13.80.0720130See
PAKPakistan Baloch0.071066See
USAUSA Caucasian pop 30.068088See
IRNIran Baloch0.0670100See
GEOGeorgia Tibilisi Kurd0.067031See
GRCGreece pop 60.0661242See
CHNChina Han HIV negative0.063072See
CHNChina Henan HIV negative0.063016See
CHESwitzerland Graubunden0.0623759See
DEUGermany DKMS - Greece minority0.06131894See
ISRIsrael Druze0.05945914See
ITAItaly Bergamo11.90.0590101See
INDIndia North pop 20.058072See
SCOScotland Orkney10.00.055099See
SDNSudan Mixed11.00.0550200See
FRAFrance Corsica Island0.0550100See
PRTPortugal North0.054046See
ISRIsrael YemenJews0.053115542See
ISRIsrael Morocco Jews0.052836718See
GNBGuinea Bissau Balanta0.052048See
DEUGermany DKMS - Italy minority0.05201159See
PAKPakistan Mixed Pathan0.0510100See
PAKPakistan Mixed Sindhi0.0510101See
PRTAzores Oriental Islands0.051043See
IRNIran Kurd pop 20.050060See
SGPSingapore SGVP. Indian INS0.050086See
USAUSA NMDP Middle Eastern or North Coast of Africa0.049370890See
CHESwitzerland Lausanne0.0493993See
ISRIsrael Iraq Jews0.049113270See
DEUGermany DKMS - Turkey minority0.04904856See
MKDMacedonia pop 40.0490216See
RUSRussia Bering Island Aleuts0.0481104See
CPVCape Verde Northwestern Islands0.048062See
GEOGeorgia Tibilisi0.0480109See
CHESwitzerland Luzern0.04781553See
CHESwitzerland Bern0.04723545See
CHESwitzerland Sion0.0470832See
CHESwitzerland St Gallen0.04502113See
CHESwitzerland Lugano0.04401169See
IRLIreland South8.80.0440250See
USAUSA Caucasian pop 20.0430265See
CHESwitzerland Geneva pop 20.04291267See
BGRBulgaria Romani0.042013See
DEUGermany DKMS - Austria minority0.04121698See
DEUGermany DKMS - Bosnia and Herzegovina minority0.04101028See
ISRIsrael Iran Jews0.04008153See
CPVCape Verde Southeastern Islands0.040062See
ISRIsrael Arab Druze0.0400101See
PRTPortugal Center0.040050See
DEUGermany DKMS - Croatia minority0.03992057See
HRVCroatia pop 40.03934000See
ESPSpain Majorca and Minorca0.039090See
USAUSA NMDP South Asian Indian0.0386185391See
DEUGermany DKMS - France minority0.03841406See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,7.50.03844335See
BFABurkina Faso Mossi0.038053See
GNBGuinea Bissau0.038065See
USAUSA Philadelphia Caucasian7.40.0370141See
ITAItaly pop 50.0370975See
DEUGermany pop 60.03688862See
ISRIsrael Libya Jews0.03653739See
DEUGermany DKMS - Romania minority0.03651234See
DEUGermany pop 80.036439689See
DEUGermany DKMS - Netherlands minority0.03641374See
DEUGermany DKMS - Portugal minority0.03611176See
CUBCuba Mixed Race7.10.036042See
CUBCuba Caucasian7.10.036070See
DEUGermany DKMS - United Kingdom minority0.03601043See
USAUSA NMDP European Caucasian0.03551242890See
PRTPortugal Azores Terceira Island7.00.0351130See
ARMArmenia combined Regions0.0350100See
CHESwitzerland Zurich0.03414875See
USAUSA San Francisco Caucasian0.0340220See
CHESwitzerland Aargau-Solothurn0.03401838See
MARMorocco Atlantic Coast Chaouya0.034098See
MARMorocco Settat Chaouya6.80.034098See
MARMorocco Nador Metalsa pop 20.034073See
AUSAustralia New South Wales Caucasian0.0340134See
FRAFrance French Bone Marrow Donor Registry0.033942623See
DEUGermany DKMS - Spain minority0.03401107See
USAUSA NMDP Caribean Hispanic0.0337115374See
GNBGuinea Bissau Fula0.032031See
NIRIreland Northern6.10.03201000See
CZECzech Republic NMDR0.03185099See
ISRIsrael Arab pop 20.031812301See
ECUEcuador Amerindians0.031763See
ZAFSouth Africa Worcester6.00.0310159See
NLDNetherlands Leiden0.03101305See
PRTPortugal South0.031049See
JORJordan Amman0.0310146See
INDIndia New Delhi0.030071See
INDIndia Khandesh Region Pawra0.030050See
INDIndia West Coast Parsi0.030050See
USAUSA Hispanic0.0300234See
ZAFSouth Africa Caucasians0.0300102See
USAUSA NMDP Southeast Asian0.029927978See
ISRIsrael Ethiopia Jews0.02995928See
CHESwitzerland Basel0.02961888See
MYSMalaysia Peninsular Indian5.90.0295271See
USAUSA NMDP Caribean Indian0.029014339See
POLPoland DKMS0.028620653See
ISRIsrael Kavkazi Jews0.02822840See
USAUSA Eastern European0.0280558See
USAUSA NMDP American Indian South or Central America0.02805926See
INDIndia Tamil Nadu0.02782492See
USAUSA Hispanic pop 20.02711999See
ENGEngland North West5.40.0270298See
PAKPakistan Burusho0.027092See
INDIndia Delhi pop 25.60.027090See
PRTAzores Central Islands0.027059See
TUNTunisia Gabes0.026395See
USAUSA Caucasian pop 40.02621070See
RUSRussia Karelia0.02611075See
USAUSA NMDP Hispanic South or Central American0.0261146714See
USAUSA San Diego5.20.0260496See
ESPSpain Andalusia Romani0.026099See
KENKenya Luo0.0260265See
ISRIsrael USSR Jews0.025745681See
ISRIsrael USA Jews0.02566058See
ISRIsrael Argentina Jews0.02554307See
USAUSA NMDP North American Amerindian0.025435791See
USAUSA NMDP Alaska Native or Aleut0.02501376See
ZAFSouth Africa Natal Zulu5.00.0250100See
ISRIsrael Ashkenazi Jews pop 30.02484625See
USAUSA NMDP Mexican or Chicano0.0247261235See
ISRIsrael Poland Jews0.024313871See
MEXMexico Mestizo4.90.024041See
CZECzech Republic0.0240106See
SAUSaudi Arabia Guraiat and Hail4.70.0240213See
CHNChina North Han0.0240105See
COLColombia Bogotá Cord Blood4.60.02391463See
MEXMexico Veracruz Xalapa4.80.023884See
IRNIran Gorgan0.023064See
MEXMexico Chihuahua Chihuahua City Pop 24.50.022788See
CHNChina Beijing0.022067See
UGAUganda Kampala0.0220161See
USAUSA Caucasian Bethesda4.40.0220307See
USAUSA San Antonio Caucasian0.0211222See
USAUSA North American Native0.0210187See
RUSRussia Tuva pop 20.0210169See
SWESweden Northern Sami0.0210154See
KENKenya, Nyanza Province, Luo tribe4.00.0200100See
USAUSA African American Bethesda3.00.0200187See
BRABrazil Mixed0.0200108See
CMRCameroon Beti0.0200174See
ISRIsrael Tunisia Jews0.02009070See
AUSAustralia Cape York Peninsula Aborigine0.0190103See
KENKenya Nandi0.0190240See
ITAItaly North pop 33.80.019097See
MYSMalaysia Kelantan3.60.018028See
CHNChina Jiangsu Province Han0.0174334See
USAUSA South Texas Hispanic0.0170194See
USAUSA African American pop 20.0170149See
CHNChina Jiangsu Han0.01683238See
LKASri Lanka Colombo3.10.0160714See
USAUSA African American0.0160252See
BRABrazil Belo Horizonte Caucasian3.20.016095See
SGPSingapore SGVP Chinese CHS0.016096See
NLDNetherlands UMCU3.10.015664See
USAUSA NMDP African0.015428557See
CHLChile Mapuche0.015466See
USAUSA NMDP African American pop 20.0150416581See
ISRIsrael Georgia Jews0.01484471See
USAUSA African American pop 40.01412411See
USAUSA African American pop 30.0140564See
MEXMexico Mexico City Tlalpan2.70.0136330See
USAUSA NMDP Caribean Black0.013333328See
ISRIsrael Bukhara Jews0.01322317See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0130146See
GEOGeorgia Svaneti Region Svan0.013080See
USAUSA Asian pop 20.01301772See
DEUGermany DKMS - China minority0.01291282See
SWESweden Southern Sami0.0120130See
NICNicaragua Managua2.40.0120339See
NCLNew Caledonia0.012065See
SGPSingapore SGVP Malay MAS0.012089See
VENVenezuela Colonia Tovar0.011686See
SENSenegal Niokholo Mandenka0.0110165See
INDIndia Andhra Pradesh Golla0.0110111See
CMRCameroon Yaounde0.011092See
USAUSA NMDP Hawaiian or other Pacific Islander0.011011499See
COLColombia North Chimila Amerindians0.010647See
MEXMexico Mixtec0.010097See
ESPSpain Gipuzkoa Basque0.0100100See
CMRCameroon Bakola Pygmy2.00.010050See
CHNChina Inner Mongolia Region0.0100102See
SGPSingapore Javaneses0.010051See
ZAFSouth Africa Natal Tamil0.010051See
VENVenezuela Caracas Mestizo0.010050See
MEXMexico Guadalajara Mestizo pop 20.0100103See
MEXMexico Oaxaca Jamiltepec Mixtec0.010096See
ZWEZimbabwe Harare Shona0.0090230See
CHNChina Qinghai Province Hui0.0090110See
CHNChina Tibet Region Tibetan0.0090158See
CHNChina Marrow Donor Registry0.0090600See
UGAUganda Kampala pop 20.0090175See
MEXMexico Mexico City Mestizo pop 20.0085234See
STPSao Tome Island Forro0.008066See
CHNChina Beijing Shijiazhuang Tianjian Han0.0080618See
USAUSA Asian0.0080358See
MLIMali Bandiagara0.0070138See
SGPSingapore Chinese1.30.0070149See
MEXMexico Oaxaca Zapotec0.007090See
AUSAustralia Groote Eylandt Aborigine0.007075See
USAUSA NMDP Chinese0.006299672See
KORSouth Korea pop 100.00614128See
USAUSA NMDP Korean0.006177584See
ITAItaly North Pavia0.006081See
ESPSpain Catalonia Girona0.006088See
CHNChina Yunnan Province Nu0.0060107See
INDIndia Mumbai Maratha0.006091See
ARGArgentina Rosario Toba1.20.006086See
TWNTaiwan Minnan pop 11.00.0050102See
CHLChile Santiago Mixed1.00.005070See
TWNTaiwan Han Chinese0.0050504See
IDNIndonesia Sundanese and Javanese0.0050201See
TWNTaiwan Tzu Chi Morrow Donor Registry0.004646682See
MYSMalaysia Peninsular Malay0.80.0042951See
TWNTaiwan Tzu Chi Cord Blood Bank0.0040710See
SGPSingapore Riau Malay0.0040132See
HKGHong Kong Chinese0.70.0040569See
HKGHong Kong Chinese cord blood registry0.00393892See
KORSouth Korea pop 30.0030485See
AUSAustralia Yuendumu Aborigine0.0030191See
USAUSA NMDP Filipino0.002850614See
HKGHong Kong Chinese BMDR0.00247595See
TWNTaiwan pop 20.0020364See
THAThailand Northeast0.002066See
USAUSA South Dakota Lakota Sioux0.0020302See
USAUSA NMDP Vietnamese0.001743540See
USAUSA NMDP Japanese0.001724582See
THAThailand Northeast pop 20.0010400See
JPNJapan pop 160.000218604See
STPSao Tome Island Angolar0.000032See
IDNIndonesia Java pop 20.000036See
GNBGuinea Bissau Papel0.000025See
GNBGuinea Bissau Bijago0.000023See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
BFABurkina Faso Rimaibe0.000047See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
CHNChina Guangzhou0.0000102See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Wanigela Keapara0.000066See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CMRCameroon Bamileke0.000077See
INDIndia West Bhil0.000050See
MEXMexico Oaxaca Mixtec0.0000103See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
USAUSA Alaska Yupik0.0000252See
ZMBZambia Lusaka0.000044See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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