Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 241 time(s) and present in 214 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHLChile Mapuche0.353866See
MEXMexico Veracruz Xalapa33.30.178684See
MEXMexico Chiapas Lacandon Mayans0.1445218See
MEXMexico Mexico City Tlalpan25.80.1379330See
ARGArgentina Rosario Toba22.10.122086See
BRABrazil Puyanawa22.00.1200150See
COLColombia North Chimila Amerindians0.106347See
AREUnited Arab Emirates Abu Dhabi0.096252See
BFABurkina Faso Mossi0.094053See
INDIndia Delhi pop 218.90.094090See
MEXMexico Chihuahua Tarahumara0.091044See
COLColombia North Wiwa El Encanto0.086552See
PAKPakistan Burusho0.082092See
RUSRussia Bering Island Aleuts0.0817104See
MEXMexico Mexico City Mestizo pop 20.0791234See
SENSenegal Niokholo Mandenka0.0700165See
USAUSA NMDP South Asian Indian0.0676185391See
USAUSA NMDP Alaska Native or Aleut0.06401376See
LKASri Lanka Colombo11.90.0640714See
ECUEcuador Amerindians0.063563See
GEOGeorgia Svaneti Region Svan0.063080See
PRTPortugal Center0.060050See
INDIndia Tamil Nadu0.05862492See
SDNSudan East Rashaida11.10.057127See
IRNIran Tabriz Azeris0.056797See
USAUSA North American Native0.0560187See
SAUSaudi Arabia Guraiat and Hail9.90.0560213See
SGPSingapore SGVP. Indian INS0.056086See
NICNicaragua Managua10.80.0554339See
CHESwitzerland Sion0.0544832See
IRNIran Yazd0.053656See
USAUSA South Texas Hispanic0.0520194See
COLColombia Bogotá Cord Blood9.90.05191463See
USAUSA NMDP Mexican or Chicano0.0518261235See
CHESwitzerland Basel0.05081888See
CMRCameroon Baka Pygmy0.050010See
USAUSA NMDP Southeast Asian0.049927978See
CHESwitzerland Zurich0.04954875See
MEXMexico Mexico City Mestizo population0.0490143See
USAUSA NMDP Hispanic South or Central American0.0480146714See
SWESweden Southern Sami0.0470130See
USAUSA Hispanic pop 20.04691999See
CHESwitzerland Lugano0.04661169See
USAUSA Alaska Yupik0.0460252See
ISRIsrael Ethiopia Jews0.04595928See
MEXMexico Chihuahua Chihuahua City Pop 29.10.045588See
PAKPakistan Mixed Sindhi0.0450101See
SCOScotland Orkney8.80.044099See
CHESwitzerland Aargau-Solothurn0.04391838See
NLDNetherlands Leiden0.04301305See
GEOGeorgia Tibilisi0.0430109See
USAUSA NMDP Caribean Indian0.043014339See
DEUGermany DKMS - Croatia minority0.04212057See
GNBGuinea Bissau Balanta0.042048See
USAUSA NMDP American Indian South or Central America0.04205926See
CHESwitzerland St Gallen0.04162113See
AUSAustralia New South Wales Caucasian0.0410134See
DEUGermany DKMS - Greece minority0.04071894See
HRVCroatia pop 40.04014000See
USAUSA African American Bethesda7.90.0400187See
USAUSA NMDP African American pop 20.0395416581See
PRTPortugal Azores Terceira Island7.90.0395130See
DEUGermany DKMS - Austria minority0.03951698See
GRCGreece pop 60.0393242See
CHNChina Inner Mongolia Region0.0390102See
PRTAzores Terceira Island0.0390130See
DEUGermany DKMS - Turkey minority0.03894856See
USAUSA NMDP Caribean Hispanic0.0385115374See
GHAGhana Ga-Adangbe6.90.0382131See
USAUSA NMDP North American Amerindian0.038135791See
PRTAzores Oriental Islands0.038043See
STPSao Tome Island Forro0.038066See
CMRCameroon Sawa0.038013See
USAUSA NMDP African0.037828557See
DEUGermany DKMS - Bosnia and Herzegovina minority0.03751028See
USAUSA NMDP Caribean Black0.036933328See
USAUSA African American pop 40.03682411See
DEUGermany pop 60.03638862See
MLIMali Bandiagara0.0360138See
MEXMexico Mixtec0.036097See
MEXMexico Oaxaca Jamiltepec Mixtec0.036096See
DEUGermany DKMS - German donors0.03593456066See
RUSRussia Karelia0.03581075See
DEUGermany pop 80.035439689See
CHESwitzerland Luzern0.03541553See
CHESwitzerland Bern0.03503545See
ZAFSouth Africa Worcester7.00.0350159See
DEUGermany DKMS - Netherlands minority0.03481374See
IRLIreland South6.00.0340250See
USAUSA San Diego6.80.0340496See
DEUGermany DKMS - Spain minority0.03391107See
MYSMalaysia Peninsular Indian6.60.0332271See
ITAItaly pop 50.0330975See
POLPoland DKMS0.033020653See
CHESwitzerland Lausanne0.0323993See
CMRCameroon Beti0.0320174See
GNBGuinea Bissau Fula0.032031See
USAUSA NMDP European Caucasian0.03191242890See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
BFABurkina Faso Fulani0.031049See
DEUGermany DKMS - France minority0.03091406See
DEUGermany DKMS - United Kingdom minority0.03091043See
DEUGermany DKMS - Portugal minority0.03071176See
CZECzech Republic NMDR0.03035099See
USAUSA San Antonio Caucasian0.0301222See
USAUSA Caucasian pop 20.0300265See
PRTPortugal South0.030049See
SDNSudan Mixed6.00.0300200See
USAUSA Philadelphia Caucasian5.90.0300141See
ARMArmenia combined Regions0.0300100See
USAUSA NMDP Middle Eastern or North Coast of Africa0.030070890See
USAUSA Caucasian pop 40.02991070See
UGAUganda Kampala0.0280161See
ESPSpain Majorca and Minorca0.028090See
ISRIsrael Iraq Jews0.027713270See
DEUGermany DKMS - Romania minority0.02711234See
PRTAzores Central Islands0.027059See
USAUSA African American0.0260252See
USAUSA Hispanic0.0260234See
CHNChina Uyghur HIV negative0.026019See
CHESwitzerland Graubunden0.0258759See
USAUSA San Francisco Caucasian0.0250220See
ISRIsrael Arab pop 20.024112301See
PAKPakistan Baloch0.024066See
FRAFrance French Bone Marrow Donor Registry0.023842623See
NLDNetherlands UMCU4.70.023464See
IRNIran Gorgan0.023064See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,4.60.02304335See
ESPSpain Catalonia Girona0.023088See
DEUGermany DKMS - Italy minority0.02281159See
CHNChina Beijing0.022067See
GNBGuinea Bissau Bijago0.022023See
CHLChile Santiago Mixed4.00.020270See
CHESwitzerland Geneva pop 20.02001267See
FRAFrance Corsica Island0.0200100See
GNBGuinea Bissau Papel0.020025See
MYSMalaysia Patani4.00.020025See
UGAUganda Kampala pop 20.0200175See
USAUSA Asian pop 20.01861772See
ENGEngland North West3.70.0180298See
ITAItaly Bergamo2.90.0160101See
KENKenya Luo0.0150265See
MEXMexico Sonora Seri0.015034See
ESPSpain Andalusia0.015099See
USAUSA Caucasian Bethesda3.00.0150307See
ISRIsrael Kavkazi Jews0.01482840See
ISRIsrael Druze0.01455914See
SWESweden Northern Sami0.0140154See
USAUSA NMDP Hawaiian or other Pacific Islander0.013611499See
ISRIsrael YemenJews0.013215542See
CMRCameroon Bamileke0.013077See
MYSMalaysia Peninsular Malay2.50.0121951See
TZATanzania Maasai2.10.0119336See
ISRIsrael Iran Jews0.01128153See
NZLNew Zealand Maori with Admixed History1.00.0100105See
CMRCameroon Bakola Pygmy2.00.010050See
ESPSpain Gipuzkoa Basque0.0100100See
DEUGermany DKMS - China minority0.00991282See
CHNChina Qinghai Province Hui0.0090110See
ZWEZimbabwe Harare Shona0.0090230See
VNMVietnam Hanoi Kinh pop 20.0090170See
IRNIran Saqqez-Baneh Kurds0.008360See
IRNIran Kurd pop 20.008060See
ISRIsrael Ashkenazi Jews pop 30.00724625See
KENKenya Nandi0.0060240See
CMRCameroon Yaounde0.006092See
CHNChina Hubei Han1.20.00603732See
USAUSA NMDP Vietnamese0.005743540See
ISRIsrael Tunisia Jews0.00579070See
CHNChina Jiangsu Han0.00563238See
CHNChina Jiangsu Province Han0.0053334See
ISRIsrael Morocco Jews0.005236718See
ITAItaly Sardinia pop30.0050100See
KENKenya, Nyanza Province, Luo tribe1.00.0050100See
CHNChina Beijing Shijiazhuang Tianjian Han0.0050618See
AUSAustralia Cape York Peninsula Aborigine0.0050103See
SGPSingapore SGVP Chinese CHS0.005096See
ISRIsrael Bukhara Jews0.00502317See
ISRIsrael Poland Jews0.004813871See
ISRIsrael USSR Jews0.004445681See
RUSRussian Federation Vologda Region0.80.0042119See
ISRIsrael USA Jews0.00416058See
ISRIsrael Libya Jews0.00413739See
USAUSA NMDP Chinese0.004099672See
THAThailand Northeast0.004066See
THAThailand Northeast pop 20.0040400See
TWNTaiwan Han Chinese0.0040504See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0040146See
FRAFrance Southeast0.80.0040130See
CHNChina Marrow Donor Registry0.0040600See
HKGHong Kong Chinese cord blood registry0.00333892See
ISRIsrael Argentina Jews0.00334307See
USAUSA NMDP Filipino0.003250614See
USAUSA Asian0.0030358See
USAUSA NMDP Korean0.002477584See
HKGHong Kong Chinese BMDR0.00247595See
KORSouth Korea pop 100.00244128See
ISRIsrael Georgia Jews0.00204471See
USAUSA NMDP Japanese0.001724582See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
KORSouth Korea pop 30.0010485See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000246682See
JPNJapan pop 160.000118604See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
CHNChina Guangzhou0.0000102See
CHNChina North Han0.0000105See
AUSAustralia Yuendumu Aborigine0.0000191See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
PRTPortugal North0.000046See
PHLPhilippines Ivatan0.00.000050See
STPSao Tome Island Angolar0.000032See
SGPSingapore SGVP Malay MAS0.000089See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
ZMBZambia Lusaka0.000044See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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