Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 320 time(s) and present in 244 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia West Coast Parsi0.090050See
COLColombia Inga NA-DHS_11 (G)14.30.071416See
PAKPakistan Karachi Parsi0.055091See
MEXMexico Chihuahua Chihuahua City Pop 210.20.051188See
ZMBZambia Lusaka0.046044See
MEXMexico Sinaloa Mestizo0.045056See
ZAFSouth Africa Natal Zulu8.00.0400100See
MEXMexico Morelos Rural0.033330See
MEXMexico Veracruz, Poza Rica0.033345See
IRNIran Tabriz Azeris0.030997See
CUBCuba Caucasian5.70.029070See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
MEXMexico Veracruz, Coatzacoalcos0.026855See
CHLChile Huilliche NA-DHS_14 (G)5.00.025020See
MEXMexico Sinaloa Rural0.0246183See
IRLIreland South4.80.0240250See
PAKPakistan Baloch0.023066See
NIRIreland Northern4.30.02201000See
MEXMexico Campeche Rural0.021347See
KORSouth Korea pop 30.0210485See
CMRCameroon Bakola Pygmy4.00.020250See
PAKPakistan Mixed Sindhi0.0200101See
PRTPortugal South0.020049See
MEXMexico Sinaloa, Culiacán0.0194103See
COLColombia North Wiwa El Encanto0.019252See
SDNSudan East Rashaida3.70.018627See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,3.60.01854335See
MEXMexico Tabasco, Villahermosa0.018382See
MEXMexico Mexico City Tlalpan3.60.0182330See
PRTAzores Central Islands0.018059See
MEXMexico Veracruz Xalapa3.60.017984See
PRTPortugal Azores Terceira Island3.50.0175130See
MEXMexico Guerrero state0.0174144See
MEXMexico San Luis Potosi Rural0.017287See
UGAUganda Kampala0.0160161See
PRTAzores Terceira Island0.0160130See
MEXMexico Mexico City West0.014933See
DEUGermany DKMS - Spain minority0.01451107See
CMRCameroon Beti0.0140174See
MEXMexico Sonora, Ciudad Obregón0.0140143See
PAKPakistan Brahui0.0140104See
MARMorocco Nador Metalsa pop 20.014073See
SDNSudan Central Shaigiya Mixed2.70.013536See
DEUGermany DKMS - Portugal minority0.01321176See
CMRCameroon Bamileke0.013077See
USAUSA European American pop 20.01301245See
PRTAzores Oriental Islands0.013043See
ZWEZimbabwe Harare Shona0.0130230See
CHESwitzerland Lausanne0.0129993See
MEXMexico Michoacan Rural0.0129348See
ECUEcuador Amazonia Mixed Ancestry0.012839See
MEXMexico Guanajuato, Leon0.012878See
MEXMexico Jalisco, Tlaquepaque0.012839See
KORSouth Korea pop 100.01244128See
MEXMexico Morelos, Cuernavaca0.012282See
USAUSA NMDP Korean0.012277584See
MEXMexico Mestizo2.40.012041See
MEXMexico Mexico City Mestizo0.0120121See
ITAItaly pop 50.0120975See
FRAFrance Southeast2.30.0120130See
MEXMexico Jalisco, Zapopan0.0119168See
MEXMexico Tamaulipas Rural0.0119125See
FRAFrance French Bone Marrow Donor Registry0.011442623See
ISRIsrael YemenJews0.011215542See
MEXMexico Queretaro, Queretaro city0.011145See
KENKenya Luo0.0110265See
MLIMali Bandiagara0.0110138See
CMRCameroon Yaounde0.011092See
AUSAustralia New South Wales Caucasian0.0110134See
USAUSA Hispanic0.0110234See
USAUSA San Francisco Caucasian0.0110220See
CHESwitzerland Sion0.0108832See
CHESwitzerland Zurich0.01074875See
MEXMexico Mexico City Mestizo population0.0105143See
MEXMexico Aguascalientes state0.010595See
MEXMexico Yucatan, Merida0.0103192See
USAUSA NMDP European Caucasian0.01021242890See
CHESwitzerland Graubunden0.0101759See
SRBSerbia pop 22.00.0100102See
NCLNew Caledonia0.010065See
NZLNew Zealand Maori with Admixed History1.90.0100105See
MEXMexico Quintana Roo Rural0.010050See
MEXMexico Guadalajara Mestizo pop 20.0100103See
MEXMexico Oaxaca Mixtec0.0100103See
ENGEngland North West2.00.0100298See
USAUSA NMDP American Indian South or Central America0.01005926See
USAUSA NMDP Alaska Native or Aleut0.01001376See
MEXMexico Michoacan, Morelia0.0099150See
MEXMexico Durango, Durango city0.0097153See
USAUSA African American pop 40.00932411See
DEUGermany DKMS - United Kingdom minority0.00911043See
USAUSA Hispanic pop 20.00901999See
ZAFSouth Africa Worcester2.00.0090159See
USAUSA NMDP Hispanic South or Central American0.0089146714See
CHESwitzerland Basel0.00891888See
MEXMexico Veracruz, Cordoba0.008956See
COLColombia Bogotá Cord Blood1.80.00891463See
USAUSA NMDP Mexican or Chicano0.0087261235See
ECUEcuador Mixed Ancestry0.00851173See
MEXMexico Mexico City Mestizo pop 20.0085234See
ECUEcuador Coast Mixed Ancestry0.0084238See
IRNIran Saqqez-Baneh Kurds0.008360See
MEXMexico Colima, Colima city0.008261See
IRNIran Gorgan0.008064See
IRNIran Kurd pop 20.008060See
SWESweden Southern Sami0.0080130See
USAUSA African American0.0080252See
USAUSA NMDP African American pop 20.0079416581See
ECUEcuador Andes Mixed Ancestry0.0079824See
USAUSA NMDP North American Amerindian0.007935791See
DEUGermany DKMS - France minority0.00781406See
MEXMexico Nayarit Rural0.007864See
NLDNetherlands UMCU1.60.007864See
CHLChile Mapuche0.007766See
MEXMexico Durango Rural0.0076326See
MEXMexico Sonora Rural0.0076197See
USAUSA Caucasian pop 40.00751070See
USAUSA NMDP African0.007428557See
MEXMexico Zacatecas Rural0.0074266See
CHESwitzerland Geneva pop 20.00731267See
CHESwitzerland Bern0.00713545See
USAUSA Italy Ancestry0.0070273See
USAUSA African American pop 80.0070605See
MEXMexico Tabasco Rural0.0070142See
MARMorocco Atlantic Coast Chaouya0.007098See
MARMorocco Settat Chaouya1.40.007098See
AUSAustralia Groote Eylandt Aborigine0.007075See
USAUSA NMDP Caribean Hispanic0.0067115374See
DEUGermany DKMS - Italy minority0.00651159See
USAUSA NMDP Caribean Black0.006233328See
DEUGermany DKMS - Austria minority0.00621698See
MEXMexico Guanajuato Rural0.0061162See
MEXMexico Zacatecas, Zacatecas city0.006084See
USAUSA Arizona Pima0.0060100See
USAUSA African American pop 30.0060564See
TUNTunisia pop 30.0060104See
USAUSA San Antonio Caucasian0.0060222See
DEUGermany DKMS - German donors0.00553456066See
DEUGermany DKMS - Netherlands minority0.00551374See
MEXMexico Mexico City North0.0053751See
MEXMexico Sonora, Hermosillo0.005199See
MEXMexico Jalisco Rural0.0051585See
MEXMexico Oaxaca Jamiltepec Mixtec0.005096See
NLDNetherlands Leiden0.00501305See
PAKPakistan Mixed Pathan0.0050100See
ZAFSouth Africa Caucasians0.0050102See
CHESwitzerland Luzern0.00501553See
SDNSudan Mixed1.00.0050200See
USAUSA Mexican American Mestizo0.0050553See
USAUSA Spain Ancestry0.0050279See
MEXMexico Mixtec0.005097See
FRAFrance Reims0.0050102See
ARMArmenia combined Regions0.0050100See
AUSAustralia Cape York Peninsula Aborigine0.0050103See
BRABrazil Belo Horizonte Caucasian1.10.005095See
USAUSA African American Bethesda1.10.0050187See
USAUSA North American Native0.0050187See
USAUSA NMDP Caribean Indian0.005014339See
USAUSA NMDP Middle Eastern or North Coast of Africa0.004970890See
DEUGermany pop 80.004939689See
CHESwitzerland St Gallen0.00492113See
RUSRussia Bering Island Aleuts0.0048104See
MEXMexico Puebla, Puebla city0.00481994See
MEXMexico Zacatecas, Fresnillo0.0048103See
MEXMexico Jalisco, Guadalajara city0.00461189See
MEXMexico Veracruz Rural0.0046539See
NICNicaragua Managua0.90.0045339See
DEUGermany pop 60.00468862See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00441028See
MEXMexico Chihuahua Chihuahua City0.0042119See
CZECzech Republic NMDR0.00415099See
CHESwitzerland Aargau-Solothurn0.00401838See
USAUSA Eastern European0.0040558See
USAUSA Caucasian pop 20.0040265See
USAUSA South Texas Hispanic0.0040194See
MEXMexico Tlaxcala Rural0.0036830See
POLPoland DKMS0.003520653See
HRVCroatia pop 40.00344000See
DEUGermany DKMS - Croatia minority0.00342057See
ISRIsrael Arab pop 20.003312301See
MEXMexico Mexico City Center0.0032152See
MEXMexico Oaxaca Rural0.0031485See
AREUnited Arab Emirates pop 20.50.0030373See
UGAUganda Kampala pop 20.0030175See
CHESwitzerland Lugano0.00301169See
JORJordan Amman0.0030146See
DEUGermany Essen0.60.0030174See
USAUSA San Diego0.60.0030496See
TZATanzania Maasai0.60.0030336See
USAUSA NMDP Hawaiian or other Pacific Islander0.002811499See
USAUSA Asian pop 20.00281772See
MEXMexico Veracruz, Xalapa0.0027187See
MEXMexico Coahuila, Torreon0.0025396See
MEXMexico Puebla Rural0.0024833See
GRCGreece pop 60.0024242See
DEUGermany DKMS - Greece minority0.00241894See
MEXMexico Nuevo Leon Rural0.0023439See
MEXMexico Nuevo Leon, Monterrey city0.0022226See
DEUGermany DKMS - Turkey minority0.00214856See
MEXMexico Chihuahua Rural0.0021236See
USAUSA Arizona Gila River Amerindian0.0020492See
CHNChina Canton Han0.0020264See
CHNChina South Han0.0020284See
KENKenya Nandi0.0020240See
MKDMacedonia pop 40.0020216See
SAUSaudi Arabia pop 6 (G)0.002028927See
RUSRussia Karelia0.00191075See
ISRIsrael Ethiopia Jews0.00195928See
ISRIsrael Tunisia Jews0.00189070See
DEUGermany DKMS - Romania minority0.00161234See
ISRIsrael Libya Jews0.00113739See
USAUSA NMDP Filipino0.001050614See
USAUSA Asian0.0010358See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
ISRIsrael USA Jews0.00086058See
USAUSA NMDP Japanese0.000724582See
ISRIsrael Argentina Jews0.00054307See
ISRIsrael USSR Jews0.000545681See
ISRIsrael Ashkenazi Jews pop 30.00044625See
ISRIsrael Poland Jews0.000413871See
ISRIsrael Morocco Jews0.000436718See
USAUSA NMDP Southeast Asian0.000427978See
ISRIsrael Kavkazi Jews0.00042840See
DEUGermany DKMS - China minority0.00041282See
CHNChina Jiangsu Han0.00033238See
USAUSA NMDP Chinese0.000299672See
JPNJapan pop 160.000218604See
USAUSA NMDP South Asian Indian0.0002185391See
USAUSA NMDP Vietnamese0.000243540See
ISRIsrael Iraq Jews0.000113270See
CHNChina Hubei Han0.00.00013732See
ISRIsrael Iran Jews0.00018153See
ISRIsrael Bukhara Jews0.00002317See
ITAItaly North pop 30.00.000097See
MEXMexico Oaxaca Zapotec0.000090See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Mexico City East0.000079See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Puebla Mestizo0.000099See
MEXMexico Oaxaca, Oaxaca city0.0000151See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
AUSAustralia Yuendumu Aborigine0.0000191See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina North Han0.0000105See
CUBCuba Mixed Race0.00.000042See
HKGHong Kong Chinese0.00.0000569See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
SGPSingapore Chinese0.00.0000149See
PRTPortugal North0.000046See
PRTPortugal Center0.000050See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
MEXMexico Baja California Rural0.000050See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Queretaro Rural0.000043See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Colima Rural0.000043See
MEXMexico Coahuila Rural0.0000216See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Wanigela Keapara0.000066See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PHLPhilippines Ivatan0.00.000050See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Yucatan Rural0.0000132See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA Alaska Yupik0.0000252See
USAUSA Philadelphia Caucasian0.00.0000141See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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